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1. 发明申请

US20060014302A1 Point of care diagnostic systems 审中-公开
公开(公告)号：US20060014302A1
公开(公告)日：2006-01-19
申请号：US11219216
申请日：2005-09-02
申请人： Ricardo Martinez , Gail Marzolf , Ronald Pong , Lynn Jones , Robert Hussa , Andrew Senyei , Emory Anderson , Edward Nemec , Jerome Lapointe , Duane Desieno
发明人： Ricardo Martinez , Gail Marzolf , Ronald Pong , Lynn Jones , Robert Hussa , Andrew Senyei , Emory Anderson , Edward Nemec , Jerome Lapointe , Duane Desieno
IPC分类号： G01N33/48 , C12M1/34 , G01N33/543
CPC分类号： G01N21/474 , G01N21/8483 , G01N33/558 , G01N33/6887 , G01N33/689 , G01N2333/78 , G01N2800/368 , G06F19/321 , G16H10/40 , G16H10/60 , G16H15/00 , G16H50/20 , Y02A90/26 , Y10S436/811 , Y10S436/814
摘要： Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate result is desired. The systems and methods process patient data, particularly data from point of care diagnostic tests or assays, including immunoassays, electrocardiograms, X-rays and other such tests, and provide an indication of a medical condition or risk or absence thereof. The systems include an instrument for reading or evaluating the test data and software for converting the data into diagnostic or risk assessment information.

2. 发明授权

US06394952B1 Point of care diagnostic systems 失效
标题翻译：护理点诊断系统
公开(公告)号：US06394952B1
公开(公告)日：2002-05-28
申请号：US09063497
申请日：1998-04-20
申请人： Emory V. Anderson , Jerome Lapointe , Ricardo Martinez , Gail Marzolf , Ronald Pong , Lynn Jones , Robert O. Hussa , Edward Nemec , Andrew E. Senyei , Duane DeSieno
发明人： Emory V. Anderson , Jerome Lapointe , Ricardo Martinez , Gail Marzolf , Ronald Pong , Lynn Jones , Robert O. Hussa , Edward Nemec , Andrew E. Senyei , Duane DeSieno
IPC分类号： A61B500
CPC分类号： G01N21/474 , G01N21/8483 , G01N33/558 , G01N33/6887 , G01N33/689 , G01N2333/78 , G01N2800/368 , G06F19/00 , G06F19/321 , G16H10/40 , G16H10/60 , G16H15/00 , G16H50/20 , Y02A90/26 , Y10S436/811 , Y10S436/814
摘要： Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate result is desired. The systems and methods process patient data, particularly data from point of care diagnostic tests or assays, including immunoassays, electrocardiograms, X-rays and other such tests, and provide an indication of a medical condition or risk or absence thereof. The systems include an instrument for reading or evaluating the test data and software for converting the data into diagnostic or risk assessment information.
摘要翻译：提供了用于医疗诊断或患者风险评估的系统和方法。这些系统和方法被设计为在护理点使用，例如在急诊室和手术室中，或在需要快速和准确的结果的任何情况下使用。系统和方法处理患者数据，特别是来自护理诊断测试或测定的数据，包括免疫测定，心电图，X射线和其他此类测试，并提供医疗状况或其风险或不存在的指示。系统包括用于读取或评估测试数据的工具，以及用于将数据转换为诊断或风险评估信息的软件。

3. 发明授权

US06936476B1 Point of care diagnostic systems 有权
公开(公告)号：US06936476B1
公开(公告)日：2005-08-30
申请号：US09717355
申请日：2000-11-20
申请人： Emory V. Anderson , Jerome Lapointe , Ricardo Martinez , Gail Marzolf , Ronald Pong , Lynn Jones , Robert O. Hussa , Edward Nemec , Andrew E. Senyei , Duane DeSieno
发明人： Emory V. Anderson , Jerome Lapointe , Ricardo Martinez , Gail Marzolf , Ronald Pong , Lynn Jones , Robert O. Hussa , Edward Nemec , Andrew E. Senyei , Duane DeSieno
IPC分类号： G01N33/53 , G01N21/27 , G01N21/47 , G01N33/558 , G01N33/68 , G06F19/00 , G06Q50/00 , B01N33/543
CPC分类号： G01N21/474 , G01N21/8483 , G01N33/558 , G01N33/6887 , G01N33/689 , G01N2333/78 , G01N2800/368 , G06F19/00 , G06F19/321 , G16H10/40 , G16H10/60 , G16H15/00 , G16H50/20 , Y02A90/26 , Y10S436/811 , Y10S436/814
摘要： Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate result is desired. The systems and methods process patient data, particularly data from point of care diagnostic tests or assays, including immunoassays, electrocardiograms, X-rays and other such tests, and provide an indication of a medical condition or risk or absence thereof. The systems include an instrument for reading or evaluating the test data and software for converting the data into diagnostic or risk assessment information.

4. 发明授权

US06267722B1 Point of care diagnostic systems 失效
标题翻译：护理点诊断系统
公开(公告)号：US06267722B1
公开(公告)日：2001-07-31
申请号：US09017901
申请日：1998-02-03
申请人： Emory V. Anderson , Edward Nemec , Jerome Lapointe , Duane DeSieno , Ricardo Martinez , Gail Marzolf , Ronald Pong , Lynn Jones , Robert O. Hussa , Andrew E. Senyei
发明人： Emory V. Anderson , Edward Nemec , Jerome Lapointe , Duane DeSieno , Ricardo Martinez , Gail Marzolf , Ronald Pong , Lynn Jones , Robert O. Hussa , Andrew E. Senyei
IPC分类号： A61B500
CPC分类号： G01N21/474 , G01N21/8483 , G06F19/00 , G16H10/60 , G16H15/00 , Y02A90/26 , Y10S436/811 , Y10S436/814
摘要： Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate result is desired. The systems and methods process patient data, particularly data from point of care diagnostic tests or assays, including immunoassays, electrocardiograms, X-rays and other such tests, and provide an indication of a medical condition or risk or absence thereof. The systems include an instrument for reading or evaluating the test data and software for converting the data into diagnostic or risk assessment information.
摘要翻译：提供了用于医疗诊断或患者风险评估的系统和方法。这些系统和方法被设计为在护理点使用，例如在急诊室和手术室中，或在需要快速和准确的结果的任何情况下使用。系统和方法处理患者数据，特别是来自护理诊断测试或测定的数据，包括免疫测定，心电图，X射线和其他此类测试，并提供医疗状况或其风险或不存在的指示。系统包括用于读取或评估测试数据的工具，以及用于将数据转换为诊断或风险评估信息的软件。

5. 发明授权

US06867051B1 Point of care diagnostic systems 有权
标题翻译：护理点诊断系统
公开(公告)号：US06867051B1
公开(公告)日：2005-03-15
申请号：US09717478
申请日：2000-11-20
申请人： Emory V. Anderson , Jerome Lapointe , Ricardo Martinez , Gail Marzolf , Ronald Pong , Lynn Jones , Robert O. Hussa , Edward Nemec , Andrew E. Senyei , Duane DeSieno
发明人： Emory V. Anderson , Jerome Lapointe , Ricardo Martinez , Gail Marzolf , Ronald Pong , Lynn Jones , Robert O. Hussa , Edward Nemec , Andrew E. Senyei , Duane DeSieno
IPC分类号： G01N33/53 , G01N21/27 , G01N21/47 , G01N33/558 , G01N33/68 , G06F19/00 , G06Q50/00 , G01N33/543
CPC分类号： G01N21/474 , G01N21/8483 , G01N33/558 , G01N33/6887 , G01N33/689 , G01N2333/78 , G01N2800/368 , G06F19/00 , G06F19/321 , G16H10/40 , G16H10/60 , G16H15/00 , G16H50/20 , Y02A90/26 , Y10S436/811 , Y10S436/814
摘要： Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate result is desired. The systems and methods process patient data, particularly data from point of care diagnostic tests or assays, including immunoassays, electrocardiograms, X-rays and other such tests, and provide an indication of a medical condition or risk or absence thereof. The systems include an instrument for reading or evaluating the test data and software for converting the data into diagnostic or risk assessment information.
摘要翻译：提供了用于医疗诊断或患者风险评估的系统和方法。这些系统和方法被设计为在护理点使用，例如在急诊室和手术室中，或在需要快速和准确的结果的任何情况下使用。系统和方法处理患者数据，特别是来自护理诊断测试或测定的数据，包括免疫测定，心电图，X射线和其他此类测试，并提供医疗状况或其风险或不存在的指示。系统包括用于读取或评估测试数据的工具，以及用于将数据转换为诊断或风险评估信息的软件。

6. 发明申请

US20060008923A1 Point of care diagnostic systems 审中-公开
公开(公告)号：US20060008923A1
公开(公告)日：2006-01-12
申请号：US11218807
申请日：2005-09-02
申请人： Emory Anderson , Edward Nemec , Jerome Lapointe , Duane Desieno , Ricardo Martinez , Robert Hussa
发明人： Emory Anderson , Edward Nemec , Jerome Lapointe , Duane Desieno , Ricardo Martinez , Robert Hussa
IPC分类号： G01N33/48 , G06F19/00
CPC分类号： G01N21/474 , G01N21/8483 , G01N33/558 , G01N33/6887 , G01N33/689 , G01N2333/78 , G01N2800/368 , G06F19/321 , G16H10/40 , G16H10/60 , G16H15/00 , G16H50/20 , Y02A90/26 , Y10S436/811 , Y10S436/814
摘要： Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate result is desired. The systems and methods process patient data, particularly data from point of care diagnostic tests or assays, including immunoassays, electrocardiograms, X-rays and other such tests, and provide an indication of a medical condition or risk or absence thereof. The systems include an instrument for reading or evaluating the test data and software for converting the data into diagnostic or risk assessment information.

7. 发明申请

US20060024723A1 Methods for detecting oncofetal fibronectin 有权
公开(公告)号：US20060024723A1
公开(公告)日：2006-02-02
申请号：US11193789
申请日：2005-07-29
申请人： Robert Hussa , Mark Fischer-Colbrie , Jerome Lapointe , Simon Shorter , Andrew Senyei
发明人： Robert Hussa , Mark Fischer-Colbrie , Jerome Lapointe , Simon Shorter , Andrew Senyei
IPC分类号： C12Q1/68 , G01N33/53
CPC分类号： G01N33/689 , B01L3/5023 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07K16/18 , C07K16/30 , C12Q1/6834 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/564 , G01N33/57476 , G01N33/6887 , G01N2333/471 , G01N2333/78 , G01N2500/00 , G01N2800/36 , G01N2800/368
摘要： Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronection for selection of concepti are provided.

8. 发明授权

US06678669B2 Method for selecting medical and biochemical diagnostic tests using neural network-related applications 失效
标题翻译：使用神经网络相关应用程序选择医学和生化诊断测试的方法
公开(公告)号：US06678669B2
公开(公告)日：2004-01-13
申请号：US08912133
申请日：1997-08-14
申请人： Jerome Lapointe , Duane DeSieno
发明人： Jerome Lapointe , Duane DeSieno
IPC分类号： G06N302
CPC分类号： G16H50/20 , G06F19/00 , G16H10/20 , G16H10/60 , G16H15/00 , G16H50/70
摘要： Methods are provided for developing medical diagnostic tests using decision-support systems, such as neural networks. Patient data or information, typically patient history or clinical data, are analyzed by the decision-support systems to identify important or relevant variables and decision-support systems are trained on the patient data. Patient data are augmented by biochemical test data, or results, where available, to refine performance. The resulting decision-support systems are employed to evaluate specific observation values and test results, to guide the development of biochemical or other diagnostic tests, too assess a course of treatment, to identify new diagnostic tests and disease markers, to identify useful therapies, and to provide the decision-support functionality for the test. Methods for identification of important input variables for a medical diagnostic tests for use in training the decision-support systems to guide the development of the tests, for improving the sensitivity and specificity of such tests, and for selecting diagnostic tests that improve overall diagnosis of, or potential for, a disease state and that permit the effectiveness of a selected therapeutic protocol to be assessed are provided. The methods for identification can be applied in any field in which statistics are used to determine outcomes. A method for evaluating the effectiveness of any given diagnostic test is also provided.
摘要翻译：提供了使用决策支持系统（如神经网络）开发医疗诊断测试的方法。患者数据或信息（通常为患者病史或临床数据）由决策支持系统进行分析，以确定重要或相关变量，并对患者数据进行培训。患者数据通过生物化学测试数据或结果（如果可用）来增强，以提高性能。由此产生的决策支持系统用于评估具体的观察值和测试结果，指导生物化学或其他诊断测试的开发，同时评估治疗过程，确定新的诊断测试和疾病标志物，以确定有用的治疗方法，以及为测试提供决策支持功能。识别用于培训决策支持系统的医学诊断测试的重要输入变量的方法，以指导测试的开发，用于提高这些测试的灵敏度和特异性，以及选择改善整体诊断的诊断测试，或潜在的疾病状态，并且允许评估所选择的治疗方案的有效性。识别方法可以应用于统计学用于确定结果的任何领域。还提供了用于评估任何给定诊断测试的有效性的方法。

9. 发明申请

US20060024724A1 Oncofetal fibronectin as a marker for health and disease 审中-公开
标题翻译： Oncofetal纤连蛋白作为健康和疾病的标志物
公开(公告)号：US20060024724A1
公开(公告)日：2006-02-02
申请号：US11193806
申请日：2005-07-29
申请人： Robert Hussa , Mark Fischer-Colbrie , Jerome Lapointe , Simon Shorter
发明人： Robert Hussa , Mark Fischer-Colbrie , Jerome Lapointe , Simon Shorter
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： G01N33/689 , B01L3/5023 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07K16/18 , C07K16/30 , C12Q1/6834 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/564 , G01N33/57476 , G01N33/6887 , G01N2333/471 , G01N2333/78 , G01N2500/00 , G01N2800/36 , G01N2800/368
摘要： Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronection for selection of concepti are provided.
摘要翻译：提供了检测样品中表达分子的支原体纤连蛋白的方法和产品。提供了成骨纤维连接蛋白成像方法。在本文提供的一些方法中，用试剂处理样品和/或与非特异性粘合剂接触。提供了测试受试者以确定健康和疾病状态并评估发展疾病或病症的风险的方法。还提供了通过各种方法如免疫测定和质谱法检测指示分子的成纤维细胞蛋白的存在的方法。提供了用于检测骨髓纤维连接以选择概念的方法和产品。

10. 发明申请

US20060024722A1 Samples for detection of oncofetal fibronectin and uses thereof 审中-公开
标题翻译：用于检测成纤维细胞纤连蛋白的样品及其用途
公开(公告)号：US20060024722A1
公开(公告)日：2006-02-02
申请号：US11193771
申请日：2005-07-29
申请人： Mark Fischer-Colbrie , Jerome Lapointe , Durlin Hickok
发明人： Mark Fischer-Colbrie , Jerome Lapointe , Durlin Hickok
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： G01N33/689 , B01L3/5023 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07K16/18 , C07K16/30 , C12Q1/6834 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/564 , G01N33/57476 , G01N33/6887 , G01N2333/471 , G01N2333/78 , G01N2500/00 , G01N2800/36 , G01N2800/368
摘要： Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronection for selection of concepti are provided.
摘要翻译：提供了检测样品中表达分子的支原体纤连蛋白的方法和产品。提供了成骨纤维连接蛋白成像方法。在本文提供的一些方法中，用试剂处理样品和/或与非特异性粘合剂接触。提供了测试受试者以确定健康和疾病状态并评估发展疾病或病症的风险的方法。还提供了通过各种方法如免疫测定和质谱法检测指示分子的成纤维细胞蛋白的存在的方法。提供了用于检测骨髓纤维连接以选择概念的方法和产品。

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