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1. 发明申请

US20070049862A1 Method and Device for Preventing or Reducing Proliferation or Migration of Epithelial Cells at the Inside of a Lens-Capsule Bag of a Human or Animal Eye 审中-公开
标题翻译：用于预防或减少人或动物眼的镜片胶囊袋内的上皮细胞增殖或迁移的方法和装置
公开(公告)号：US20070049862A1
公开(公告)日：2007-03-01
申请号：US11553782
申请日：2006-10-27
申请人： Reinhardt Thyzel
发明人： Reinhardt Thyzel
IPC分类号： A61M1/00 , A61B17/20 , A61B19/00
CPC分类号： A61F9/00825 , A61B17/3203 , A61F2009/0087
摘要： The invention relates to a device for preventing or reducing proliferation or migration of epithelial cells at the inside of a lens capsule bag of a human or animal eye. The device comprises means for generating pressure pulses in a liquid medium inside the lens capsule bag during which the liquid medium is adjacent to or covers the epithelial cells to be removed. These pressure pulses are selected or provided in such a manner that the epithelial cells can be or are removed from the wall of the lens capsule bag by the impinging pressure pulses whereby, at the same time, no opening or comparable damage, in particular, caused by the pressure pulses occurs in the wall of the lens capsule bag when removing the epithelial cells. the invention relates to a device for preventing or reducing proliferation or migration of epithelial cells at the inside of a lens capsule bag of a human or animal eye. The device comprises means for generating pressure pulses in a liquid medium inside the lens capsule bag during which the liquid medium is adjacent to or covers the epithelial cells to be removed. These pressure pulses are selected or provided in such a manner that the epithelial cells can be or are removed from the wall of the lens capsule bag by the impinging pressure pulses whereby, at the same time, no opening or comparable damage, in particular, caused by the pressure pulses occurs in the wall of the lens capsule bag when removing the epithelial cells.
摘要翻译：本发明涉及一种用于预防或减少人或动物眼的晶状体囊袋内部的上皮细胞增殖或迁移的装置。该装置包括用于在透镜胶囊袋内产生液体介质中的压力脉冲的装置，在液体介质中液体介质邻近或覆盖待移除的上皮细胞。选择或提供这些压力脉冲，使得上皮细胞可以通过撞击压力脉冲从透镜胶囊袋的壁或从其的壁移除，由此同时没有打开或类似的损伤，特别是引起当去除上皮细胞时，通过压力脉冲发生在镜片囊袋的壁中。本发明涉及用于预防或减少人或动物眼的晶状体囊袋内部的上皮细胞增殖或迁移的装置。该装置包括用于在透镜胶囊袋内产生液体介质中的压力脉冲的装置，在液体介质中液体介质邻近或覆盖待移除的上皮细胞。选择或提供这些压力脉冲，使得上皮细胞可以通过撞击压力脉冲从透镜胶囊袋的壁或从其的壁移除，由此同时没有打开或类似的损伤，特别是引起当去除上皮细胞时，通过压力脉冲发生在镜片囊袋的壁中。

2. 发明申请

US20070043340A1 Method and device for preventing or reducing proliferation or migration of epithelial cells at the inside of a lens-capsule bag of a human or animal eye 审中-公开
标题翻译：用于预防或减少人或动物眼的透镜胶囊袋内部的上皮细胞增殖或迁移的方法和装置
公开(公告)号：US20070043340A1
公开(公告)日：2007-02-22
申请号：US11588526
申请日：2006-10-26
申请人： Reinhardt Thyzel
发明人： Reinhardt Thyzel
IPC分类号： A61B18/18
CPC分类号： A61F9/00825 , A61B17/3203 , A61F2009/0087
摘要： The invention relates to a device for preventing or reducing proliferation or migration of epithelial cells at the inside of a lens capsule bag of a human or animal eye. The device comprises means for generating pressure pulses in a liquid medium inside the lens capsule bag during which the liquid medium is adjacent to or covers the epithelial cells to be removed. These pressure pulses are selected or provided in such a manner that the epithelial cells can be or are removed from the wall of the lens capsule bag by the impinging pressure pulses whereby, at the same time, no opening or comparable damage, in particular, caused by the pressure pulses occurs in the wall of the lens capsule bag when removing the epithelial cells. the invention relates to a device for preventing or reducing proliferation or migration of epithelial cells at the inside of a lens capsule bag of a human or animal eye. The device comprises means for generating pressure pulses in a liquid medium inside the lens capsule bag during which the liquid medium is adjacent to or covers the epithelial cells to be removed. These pressure pulses are selected or provided in such a manner that the epithelial cells can be or are removed from the wall of the lens capsule bag by the impinging pressure pulses whereby, at the same time, no opening or comparable damage, in particular, caused by the pressure pulses occurs in the wall of the lens capsule bag when removing the epithelial cells.
摘要翻译：本发明涉及一种用于预防或减少人或动物眼的晶状体囊袋内部的上皮细胞增殖或迁移的装置。该装置包括用于在透镜胶囊袋内产生液体介质中的压力脉冲的装置，在液体介质中液体介质邻近或覆盖待移除的上皮细胞。选择或提供这些压力脉冲，使得上皮细胞可以通过撞击压力脉冲从透镜胶囊袋的壁或从其的壁移除，由此同时没有打开或类似的损伤，特别是引起当去除上皮细胞时，通过压力脉冲发生在镜片囊袋的壁中。本发明涉及用于预防或减少人或动物眼的晶状体囊袋内部的上皮细胞增殖或迁移的装置。该装置包括用于在透镜胶囊袋内产生液体介质中的压力脉冲的装置，在液体介质中液体介质邻近或覆盖待移除的上皮细胞。选择或提供这些压力脉冲，使得上皮细胞可以通过撞击压力脉冲从透镜胶囊袋的壁或从其的壁移除，由此同时没有打开或类似的损伤，特别是引起当去除上皮细胞时，通过压力脉冲发生在镜片囊袋的壁中。

3. 发明授权

US11234865B2 Method for changing the perceptual color appearance of the iris of a human's or animal's eye 有权
公开(公告)号：US11234865B2
公开(公告)日：2022-02-01
申请号：US16340077
申请日：2017-09-20
申请人： Reinhardt Thyzel
发明人： Reinhardt Thyzel
IPC分类号： A61F9/008
摘要： The underlying invention is directed to a method for changing the human perceptual color appearance of the iris of a human's or animal's eye by selectively decreasing the density of pigments of the anterior stroma layer of the iris. The method comprises generating, by a generator module, a plurality of predefined energy quantities; and applying, by the generator module, one or more of the predefined energy quantities to the anterior stroma layer, wherein each of the predefined energy quantities is generated and applied, such that the energy quantities ablate, at least in part, melanocytes of the stroma whilst leaving non-melanocyte tissue of at least the stroma essentially undamaged, and wherein the predefined energy quantities generated and applied to the anterior stroma layer in the form of pressure waves and/or pulses generated within a fluid medium that is in fluidical communication with the anterior stroma layer.

4. 发明申请

US20200093637A1 DEVICE AND OPERATIONAL METHOD FOR PLASMA TREATMENT OF BIOLOGICAL TISSUE 审中-公开
公开(公告)号：US20200093637A1
公开(公告)日：2020-03-26
申请号：US16582898
申请日：2019-09-25
申请人： Reinhardt Thyzel
发明人： Reinhardt Thyzel
IPC分类号： A61F9/007
摘要： A device for plasma treatment of biological tissue can comprise a hollow needlelike tubular section with a distal end for applying a light-induced plasma to the tissue, wherein the tubular section comprises subsequent to the distal end an inner plasma chamber configured for generating therein a light-induced plasma. In one embodiment, the plasma chamber is communicatively coupled with a distal, central axial aperture in the distal end, and adjoins, within the tubular section, a light injection section for injecting light, in particular laser light pulses, into the plasma chamber for plasma generation.

5. 发明申请

US20120172408A1 ACTIVE INGREDIENT COMPRISING INDOCYANINE GREEN AND/OR INFRACYANINE GREEN 审中-公开
标题翻译：主要成分包括印度尼西亚绿色和/或葡萄糖绿色
公开(公告)号：US20120172408A1
公开(公告)日：2012-07-05
申请号：US13181295
申请日：2011-07-12
申请人： Reinhardt Thyzel
发明人： Reinhardt Thyzel
IPC分类号： A61K31/403 , A61P31/00 , A61P29/00 , C07D403/06
CPC分类号： A61K41/0057 , A61K6/0041 , A61K6/0061 , A61K6/0067 , A61K31/404 , A61N5/062
摘要： The present invention relates to an active ingredient including indocyanine green and/or infracyanine green for use in treating dental or periodontal infectious diseases under irradiation with light, more particularly laser light, from a wavelength range between 790 nm and 830 nm.
摘要翻译：本发明涉及包含吲哚菁绿和/或赤霉素绿的活性成分，用于治疗牙齿或牙周感染性疾病，在光线照射下，特别是激光，从790nm和830nm之间的波长范围。

6. 发明授权

US5258992A Laser tube for a gas laser 失效
标题翻译：激光管用于气体激光
公开(公告)号：US5258992A
公开(公告)日：1993-11-02
申请号：US895887
申请日：1992-06-10
申请人： Reinhardt Thyzel
发明人： Reinhardt Thyzel
IPC分类号： H01S3/034 , H01S3/086 , H01S3/03
CPC分类号： H01S3/086 , H01S3/034
摘要： A laser tube for a gas laser that has on at least one end side a tube flange for the detachable fastening of a laser window or of a laser mirror. The laser tube has a first adjusting flange that is gastightly mounted on the tube flange, an elastic tube-shaped element, in the interior of which the laser beam extends, and which is gastightly connected with the adjusting flange. On its other end, the tube-shaped element is gastightly connected with a second adjusting flange at which a mirror flange is gastightly mounted which carries the laser window or the laser mirror. Between the two adjusting flanges, at least two adjusting screws and at least one element which generates a restoring force are inserted.
摘要翻译：一种用于气体激光器的激光管，其在至少一个端侧具有用于激光窗口或激光反射镜的可拆卸紧固的管法兰。激光管具有气密地安装在管凸缘上的第一调节凸缘，弹性管状元件，其内部激光束延伸，并且与调节凸缘气密连接。在另一端，管状元件与第二调节凸缘气密性地连接，在第二调节凸缘处，气密地安装反射镜法兰，其携带激光窗或激光反射镜。在两个调节凸缘之间插入至少两个调节螺钉和产生恢复力的至少一个元件。

7. 发明授权

US08715273B2 Method and device for removing and/or inhibiting of molecular structures and/or cells from or at human or animal tissue 有权
标题翻译：从人体或动物组织中去除和/或抑制分子结构和/或细胞的方法和装置
公开(公告)号：US08715273B2
公开(公告)日：2014-05-06
申请号：US11944597
申请日：2007-11-23
申请人： Reinhardt Thyzel
发明人： Reinhardt Thyzel
IPC分类号： A61B18/20
CPC分类号： A61F9/00825 , A61B17/3203 , A61F2009/0087
摘要： One exemplary method for removing and/or inhibiting unwanted molecular structures and/or cells from or at human or animal tissue, can include the steps of a) supplying fluid medium so that the fluid medium is adjacent to or covers the molecular structures and/or cells that are to be removed and/or inhibited, b) generating pressure pulses in the fluid medium, wherein preferably each pressure pulse comprises a pressure current and/or a pressure wave and/or a shock wave and/or wherein preferably the pressure pulses have the form of a pressure jet of the fluid medium that is or can be directed onto the molecular structures and/or cells, and/or exhibit at least one preferential direction or main propagation direction, c) removing the molecular structures and/or cells from the tissue by the impacting pressure pulses and/or inhibiting molecular structures and/or cells which remain at the tissue by the impacting pressure pulses, d) wherein the pressure pulses are so formed or selected that during removing and/or inhibiting of the molecular structures or cells no hole or comparable damage is produced in the adjacent tissue by the pressure pulses.
摘要翻译：从人体或动物组织中去除和/或抑制不想要的分子结构和/或细胞的一个示例性方法可以包括以下步骤：a）提供流体介质，使得流体培养基邻近或覆盖分子结构和/或要被去除和/或抑制的细胞，b）在流体介质中产生压力脉冲，其中优选地，每个压力脉冲包括压力电流和/或压力波和/或冲击波，和/或其中优选的压力脉冲具有流体介质的压力射流的形式，其是或可以被引导到分子结构和/或细胞上，和/或表现出至少一个优先方向或主要传播方向，c）去除分子结构和/或细胞通过冲击压力脉冲从组织和/或通过冲击压力脉冲抑制在组织处的分子结构和/或细胞，d）其中压力脉冲被形成或选择为dur 去除和/或抑制分子结构或细胞，通过压力脉冲在相邻组织中不产生孔或类似的损伤。

8. 发明申请

US20110301581A1 DEVICE FOR IRRADIATING TISSUE 审中-公开
标题翻译：用于辐射组织的装置
公开(公告)号：US20110301581A1
公开(公告)日：2011-12-08
申请号：US13156036
申请日：2011-06-08
申请人： Reinhardt Thyzel
发明人： Reinhardt Thyzel
IPC分类号： A61B18/22
CPC分类号： A61B18/22 , A61B2018/00434 , A61N5/06 , A61N5/0601 , A61N2005/0612 , A61N2005/063 , A61N2005/0644 , A61N2005/0659
摘要： The present application is directed to a device 1 for irradiating human or animal tissue, in particular nerves, with laser light. In order to obtain gentle and effective destruction of tissue, the device 1 comprises a laser light source L adapted to generate laser light in a wavelength between 690 nm and 710 nm, and a light guide 3 for guiding through the laser light. A first end 3a of the light guide 3 is coupled the laser light source L and a second end 3b of the light guide 3 is coupled to an applicator 2 adapted to apply the laser light to the tissue.
摘要翻译：本申请涉及用激光照射人或动物组织，特别是神经的装置1。为了获得对组织的温和和有效的破坏，装置1包括适于产生690nm和710nm之间的波长的激光的激光光源L和用于引导激光的光导3。光导3的第一端3a与激光光源L相连，导光体3的第二端3b连接到适于将激光施加到组织上的施加器2上。

9. 发明申请

US20100286672A1 Laser Scalpel 审中-公开
标题翻译：激光手术刀
公开(公告)号：US20100286672A1
公开(公告)日：2010-11-11
申请号：US12718689
申请日：2010-03-05
申请人： Rudolf Walker , Gerd Volland , Reinhardt Thyzel
发明人： Rudolf Walker , Gerd Volland , Reinhardt Thyzel
IPC分类号： A61B18/20
CPC分类号： A61B18/22 , A61B17/3211 , A61B18/24 , A61B2018/00589 , A61B2018/2261 , A61B2018/2266 , A61B2090/306
摘要： The invention is based on the object of specifying a laser scalpel, by means of which a high proportion of the laser light coupled into the scalpel body can be provided on the scalpel edge or is able to emerge therefrom. According to a first aspect, the invention is based on the idea of coupling the laser light into the scalpel body at an acute angle, with respect to the surface normal of the coupling-in surface, that is to say with respect to the direction or axis perpendicular or normal to the coupling-in surface.
摘要翻译：本发明是基于指定激光手术刀的目的，其中通过该激光手术刀可以将高比例的耦合到手术刀主体中的激光提供在解剖刀刀刃上或能够从其解除。根据第一方面，本发明基于将激光以锐角相对于接合表面的表面法线（即相对于方向或相对的方向）以锐角耦合到手术刀主体中的想法，轴垂直或垂直于耦合入表面。

10. 发明申请

US20070223862A1 Coupling Device for a Light Guide 审中-公开
标题翻译：光导耦合器
公开(公告)号：US20070223862A1
公开(公告)日：2007-09-27
申请号：US11569652
申请日：2005-10-20
申请人： Reinhardt Thyzel
发明人： Reinhardt Thyzel
IPC分类号： G02B6/26
CPC分类号： G02B6/4292 , G02B6/3825 , G02B6/3833
摘要： A coupling device includes a first coupling element having a first passage, and an end section connected to the free end of the light guide; as well as a second coupling element with a second passage for holding/fixing an intermediate section following the end section of the light guide. In one implementation, the first coupling element and the second coupling element can be detachably joined in a coupled state, where the first passage and the second passage form a common passage and/or have (or surround) a common longitudinal axis. The first passage can be configured with a funnel-shaped section that, in the coupled state, the first passage faces the second passage and widens toward the second passage. In addition, the first coupling element may be formed from ceramic material at least on its inner surface in the region of the funnel-shaped section.
摘要翻译：联接装置包括具有第一通道的第一联接元件和连接到光导的自由端的端部; 以及具有第二通道的第二联接元件，用于在导光体的端部之后保持/固定中间部分。在一个实施方式中，第一联接元件和第二联接元件可以在联接状态下可拆卸地接合，其中第一通道和第二通道形成公共通道和/或具有（或围绕）共同的纵向轴线。第一通道可以被配置为漏斗形部分，在联接状态下，第一通道面向第二通道并朝向第二通道变宽。此外，第一联接元件可以至少在其漏斗形截面区域的内表面上由陶瓷材料形成。

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