专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5610164A (Thiophen-2-yl)-piperidin or tetrahydropyridin azabicyclocarboxamides 失效
标题翻译：（噻吩-2-基） - 哌啶或四氢吡啶氮杂双环羧酰胺
公开(公告)号：US5610164A
公开(公告)日：1997-03-11
申请号：US685132
申请日：1996-07-24
申请人： Reinhardt B. Baudy , James A. Nelson , Mira A. Kanzelberger
发明人： Reinhardt B. Baudy , James A. Nelson , Mira A. Kanzelberger
IPC分类号： C07D451/02 , A61K31/435
CPC分类号： C07D451/02
摘要： This invention provides compounds having the structure ##STR1## wherein R is hydrogen, alkyl, alkenyl, alkynyl, --COR.sup.2, phenyl, or phenylalkyl; the dotted line represents an optional double bond;R.sup.1 is hydrogen, --OH, OR.sup.3, or is absent if the optional double bond is present;R.sup.2 and R.sup.3 are each, independently, alkyl, alkenyl, alkynyl, phenyl, or phenylalkyl;R.sup.4 is hydrogen, --OR.sup.5, alkyl, alkenyl, alkynyl, --COR.sup.5, --CO.sub.2 R.sup.5, --CONR.sup.5 R.sup.6, perhaloalkyl, halogen, phenyl, or phenylalkyl;R.sup.5 and R.sup.6 are each, independently, hydrogen, alkyl, alkenyl, alkynyl, phenyl, or phenylalkyl; andn=0-2or a pharmaceutically acceptable salt thereof that are useful as antipsychotic, antidepressant and anxiolytic agents useful in the treatment and relief of the symptoms of these disease states.
摘要翻译：本发明提供了具有结构“IMAGE”的化合物，其中R是氢，烷基，烯基，炔基，-COR 2，苯基或苯基烷基; 虚线表示可选的双键; R1是氢，-OH，OR3，如果存在任选的双键，则不存在; R2和R3各自独立地为烷基，烯基，炔基，苯基或苯基烷基; R 4是氢，-OR 5，烷基，烯基，炔基，-COR 5，-CO 2 R 5，-CONR 5 R 6，全卤代烷基，卤素，苯基或苯基烷基; R 5和R 6各自独立地为氢，烷基，烯基，炔基，苯基或苯基烷基; 和n = 0-2或其药学上可接受的盐，其可用作抗精神病药，抗抑郁药和抗焦虑剂，其用于治疗和缓解这些疾病状态。

2. 发明授权

US06228880B1 4-amino-(ethylamino)-oxindole dopamine autoreceptor agonists 失效
标题翻译： 4-氨基 - （乙基氨基） - 氧吲哚多巴胺自身受体激动剂
公开(公告)号：US06228880B1
公开(公告)日：2001-05-08
申请号：US09287675
申请日：1999-04-07
申请人： James A. Nelson , Mira A. Kanzelberger , Richard E. Mewshaw
发明人： James A. Nelson , Mira A. Kanzelberger , Richard E. Mewshaw
IPC分类号： A61K31404
CPC分类号： C07D209/34
摘要： Compounds having dopaminegic activity are provided, having the formula: wherein R1 and R2 are each, independently, hydrogen, C1-10 alkyl, or (CH2)mR4, wherein R4 is phenyl or naphthyl which may be substituted by one or two substituents selected from the group consisting of C1-6 alkyl, halogen, C1-6 alkoxide and trifluoromethyl and m is 1 to 5; and R3 is hydrogen or C1-6 alkyl; or pharmaceutically acceptable salts thereof.
摘要翻译：提供了具有多巴胺活性的化合物，其具有下式：其中R 1和R 2各自独立地为氢，C 1-10烷基或（CH 2）m R 4，其中R 4为苯基或萘基，其可以被一个或两个选自由C 1-6烷基，卤素，C 1-6烷氧基和三氟甲基组成的组，m为1至5; 和R 3是氢或C 1-6烷基; 其药学上可接受的盐。

3. 发明授权

US5610154A Bicyclic carboxamides 失效
标题翻译：双环甲酰胺
公开(公告)号：US5610154A
公开(公告)日：1997-03-11
申请号：US448962
申请日：1995-05-24
申请人： Ian A. Cliffe , Howard L. Mansell , Terence J. Ward , James A. Nelson , Uresh S. Shah , Mira A. Kanzelberger
发明人： Ian A. Cliffe , Howard L. Mansell , Terence J. Ward , James A. Nelson , Uresh S. Shah , Mira A. Kanzelberger
IPC分类号： A61K31/495 , A61K31/55 , A61P9/12 , A61P25/18 , A61P25/20 , A61P43/00 , C07D209/44 , C07D209/52 , C07D223/14 , C07D295/185 , C07D403/12 , C07D451/02 , C07D295/16
CPC分类号： C07D295/185 , C07D209/52 , C07D223/14 , C07D451/02
摘要： Bicyclic carboxamides of formula I ##STR1## and the pharmaceutically acceptable acid addition salts are 5-HT.sub.1A binding agents, particularly 5-HT.sub.1A antagonists and may be used, for example, as anxiolytics. In the formulaX represents --CR.sup.2 .dbd.CR.sup.2 -- or --(CR.sup.2)q--;m represents 0,1 or 2; n represents 0,1 or 2; p represents 0,1,2 or 3 and q represents 0,1,2 or 3;A is an alkylene chain of 1 or 2 carbon atoms optionally substituted by one or more lower alkyl groups,R is a mono or bicyclic aryl or heteroaryl radical,R.sup.1 is an aryl or aryl(lower)alkyl radicaland each R.sup.2 is independently hydrogen or lower alkyl.
摘要翻译：式I的双环甲酰胺（I）和药学上可接受的酸加成盐是5-HT1A结合剂，特别是5-HT 1A拮抗剂，并且可以用于例如抗焦虑剂。式X表示-CR2 = CR2-或 - （CR2）q-; m表示0,1或2; n表示0,1或2; p表示0,1,2或3，q表示0,1,2或3; A是任选被一个或多个低级烷基取代的1或2个碳原子的亚烷基链，R是单或双环芳基或杂芳基，R 1是芳基或芳基（低级）烷基，每个R 2独立地是氢或低级烷基。

4. 发明授权

US10472886B2 Micro gap roller shade system and method of installation 有权
公开(公告)号：US10472886B2
公开(公告)日：2019-11-12
申请号：US15721515
申请日：2017-09-29
申请人： James A. Nelson
发明人： James A. Nelson
IPC分类号： E06B9/42 , E06B9/44 , E06B9/72
摘要： The invention is a roller shade tube assembly with a main housing having a lumen divided into two sections by an internal spring stop. The distal end of the main housing has a recessed mounting cavity coupleable to a motor. The proximal end of the main housing has one or more interlocking fingers. A spring inside the proximal lumen abuts the spring stop. An inner guide cylinder is coupled to slide inside the main housing against the spring and coupled to a lumen of an auxiliary housing that is movably coupled to the main housing. The distal end of the auxiliary housing includes one or more complementary interlocking fingers and a second recessed mounting cavity at its proximal end. Wall mounting brackets on each side of the tube assembly are configured to fit into the recessed mounting cavities. A shade fabric is coupled to the roller shade tube assembly.

5. 发明授权

US5071988A Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives 失效
标题翻译：取代的苯甲酰基苯，联苯基和2-恶唑烷酸衍生物
公开(公告)号：US5071988A
公开(公告)日：1991-12-10
申请号：US661734
申请日：1991-02-27
申请人： Amedeo A. Failli , Anthony F. Kreft, III , John H. Musser , Annette L. Banker , James A. Nelson , Uresh S. Shah
发明人： Amedeo A. Failli , Anthony F. Kreft, III , John H. Musser , Annette L. Banker , James A. Nelson , Uresh S. Shah
IPC分类号： C07C45/00 , C07C45/63 , C07C45/72 , C07C59/90 , C07C69/738 , C07C205/45 , C07C255/40 , C07D215/14 , C07D263/32 , C07D413/12
CPC分类号： C07D413/10 , C07C205/45 , C07C255/40 , C07C45/004 , C07C45/63 , C07C45/72 , C07C59/90 , C07C69/738 , C07D215/14 , C07D263/32
摘要： There are disclosed compounds of the formulaA(CH.sub.2).sub.n O--BwhereinA is ##STR1## n is 1-2; B is ##STR2## wherein R.sup.4 and R.sup.5 are each, independently, hydrogen or lower alkyl;R.sup.6 is hydrogen, halo or nitro; ##STR3## R.sup.8 is lower alkyl; m is 0-3;and the pharmacologically acceptable salts thereof, and their use in the treatment of inflammatory conditions, such as rheumatoid arthritis, ulcerative colitis, psoriasis and other immediate hypersensitivity reactions; in the treatment of leukotriene-mediated nasobronchial obstructive air-passageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like; and as gastric cytoprotective agents.
摘要翻译：公开了式A（CH 2）n O-B的化合物，其中A是n是1-2; B是，其中R 4和R 5各自独立地是氢或低级烷基; R6是氢，卤素或硝基; R8是低级烷基; m为0-3; 及其药理学上可接受的盐及其在治疗炎性病症如类风湿性关节炎，溃疡性结肠炎，牛皮癣和其他立即超敏反应中的用途; 治疗白三烯介导的鼻支气管阻塞性通气条件如过敏性鼻炎，过敏性支气管哮喘等; 和作为胃细胞保护剂。

6. 再颁专利

USRE33334E Vehicle wash and dryer 失效
标题翻译：洗车和烘干机
公开(公告)号：USRE33334E
公开(公告)日：1990-09-18
申请号：US259339
申请日：1988-10-18
申请人： James A. Nelson
发明人： James A. Nelson
IPC分类号： B60S3/00 , B60S3/06
CPC分类号： B60S3/002 , B60S3/06
摘要： An apparatus for both washing and drying an automotive vehicle. The apparatus includes a track gantry that moves along the track and over the vehicle. Water outlets and brushes are on the gantry to wash the car. The apparatus further includes a blower, nozzle, and oscillator. The blower, also mounted on the gantry, expels air onto the vehicle. The nozzle, positioned on the blower, defines an orientation and directs the air from the blower substantially parallel to the orientation. The oscillator periodically changes the orientation of the nozzle and the direction of the air from the blower.

7. 发明授权

US4685169A Vehicle wash and dryer 失效
标题翻译：洗车和烘干机
公开(公告)号：US4685169A
公开(公告)日：1987-08-11
申请号：US769666
申请日：1985-08-26
申请人： James A. Nelson
发明人： James A. Nelson
IPC分类号： B60S3/00 , B60S3/06
CPC分类号： B60S3/002 , B60S3/06 , Y10S15/02
摘要： An apparatus for both washing and drying an automotive vehicle. The apparatus includes a track gantry that moves along the track and over the vehicle. Water outlets and brushes are on the gantry to wash the car. The apparatus further includes a blower, nozzle, and oscillator. The blower, also mounted on the gantry, expels air onto the vehicle. The nozzle, positioned on the blower, defines an orientation and directs the air from the blower substantially parallel to the orientation. The oscillator periodically changes the orientation of the nozzle and the direction of the air from the blower.
摘要翻译：一种用于洗涤和干燥机动车辆的装置。该装置包括沿轨道和车辆上方移动的轨道台架。龙门架上的出水口和刷子都要洗车。该装置还包括鼓风机，喷嘴和振荡器。也安装在龙门架上的鼓风机将空气排出到车辆上。定位在鼓风机上的喷嘴限定了取向，并将来自鼓风机的空气基本上平行于取向引导。振荡器周期性地改变喷嘴的方向和来自鼓风机的空气的方向。

8. 发明授权

US4553960A Peritoneal fluid treatment apparatus, package and method 失效
公开(公告)号：US4553960A
公开(公告)日：1985-11-19
申请号：US632956
申请日：1984-07-20
申请人： Harrison Lazarus , James A. Nelson
发明人： Harrison Lazarus , James A. Nelson
IPC分类号： A61B17/34 , A61B19/02 , A61M25/01 , A61M5/00
CPC分类号： A61B17/3415 , A61B50/33 , A61M25/0111
摘要： The cannula of a conventional intravascular catheter is placed into the peritoneal cavity through a small shallow incision in antiseptically prepared skin. The stylet or trocar of the conventional catheter is removed; and a stainless steel elongated flexible guide is inserted through the catheter's cannula into the peritoneal cavity. The catheter's cannula is removed and a flexible elongated cannula inserted into the cavity over the guide and secured in place with a suture. Fluid operation means is connected to the elongated cannula by connector means to permit fluid treatment after removal of the guide. Apparatus to effect peritoneal fluid treatment are placed in sterile openable sealed packages for storage and transport.

9. 发明授权

US4479792A Peritoneal fluid treatment apparatus, package and method 失效
标题翻译：腹膜液治疗仪，包装及方法
公开(公告)号：US4479792A
公开(公告)日：1984-10-30
申请号：US423034
申请日：1982-09-24
申请人： Harrison Lazarus , James A. Nelson
发明人： Harrison Lazarus , James A. Nelson
IPC分类号： A61B17/34 , A61B19/02 , A61M25/01 , A61M25/00
CPC分类号： A61B17/3415 , A61B50/33 , A61M25/0111
摘要： The cannula of a conventional intravascular catheter is placed into the peritoneal cavity through a small shallow incision in antiseptically prepared skin. The stylet or trocar of the conventional catheter is removed; and a stainless steel elongated flexible guide is inserted through the catheter's cannula into the peritoneal cavity. The catheter's cannula is removed and a flexible elongated cannula inserted into the cavity over the guide and secured in place with a suture. Fluid operation means is connected to the elongated cannula by connector means to permit fluid treatment after removal of the guide. Apparatus to effect peritoneal fluid treatment are placed in sterile openable sealed packages for storage and transport.
摘要翻译：常规血管内导管的插管通过在防腐剂制备的皮肤中的小的浅切口放入腹腔。去除常规导管的探针或套管针; 并且将不锈钢细长的柔性引导件穿过导管的插管插入腹膜腔中。去除导管的套管，并将柔性细长插管插入引导件上的空腔中并用缝合线固定在适当位置。流体操作装置通过连接器装置连接到细长插管，以在移除引导件之后允许流体处理。用于进行腹膜液处理的装置放置在用于储存和运输的无菌可打开的密封包装中。

10. 发明授权

US06374670B1 Non-invasive gut motility monitor 失效
标题翻译：非侵入性肠动力监测仪
公开(公告)号：US06374670B1
公开(公告)日：2002-04-23
申请号：US08402872
申请日：1995-03-13
申请人： Francis A. Spelman , Page Read , N. Mani Prakash , James A. Nelson , Charles E. Pope , Margaret Heitkemper , James D. Rothermel
发明人： Francis A. Spelman , Page Read , N. Mani Prakash , James A. Nelson , Charles E. Pope , Margaret Heitkemper , James D. Rothermel
IPC分类号： A61B522
CPC分类号： A61B5/42 , A61B5/0031 , A61B5/06 , A61B5/062
摘要： An apparatus (4) and method of non-invasive monitoring of gut motility. An ingestible magnet (10, M) is swallowed by the patient (12) and then linear and rotational movement is directionally detected by an external compass (14, 16). In preferred form, movements of the magnet (10, M) are recorded by a memory means (18) and graphically presented (20) over a period of predetermined time. An alternate embodiment includes multiple compasses (C1, C2) for directionally locating the magnet (10, M) within the patient (12).
摘要翻译：一种无创性监测肠道运动的装置（4）和方法。可摄入的磁体（10，M）被患者（12）吞咽，然后线性和旋转运动由外部指南针（14,16）定向检测。在优选形式中，磁体（10，M）的移动由存储装置（18）记录并在预定时间段内以图形方式呈现（20）。替代实施例包括用于将患者（12）内的磁体（10，M）定向定位的多个罗盘（C1，C2）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式