专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US6095648A Process and arrangement for examining a section of the eye 有权
标题翻译：检查眼睛部分的过程和安排
公开(公告)号：US6095648A
公开(公告)日：2000-08-01
申请号：US263844
申请日：1999-03-08
申请人： Reginald Birngruber , Christian Scholz , Peter Koch , Ralf Engelhardt
发明人： Reginald Birngruber , Christian Scholz , Peter Koch , Ralf Engelhardt
IPC分类号： A61B3/12 , A61B3/10
CPC分类号： A61B3/1225
摘要： Systems, methods, and apparatus are provided for deriving the relative position of an eye by tracking a boundary of the eye such as the limbus (i.e., the interface between the white sclera and the colored iris). A technique for tracking the position of the eye of patient comprises directing light to an annular region of the eye between the sclera and the iris and receiving reflected light from that region. The intensity of the reflected light is then measured to determine a relative position of the eye. In some embodiments, the measured region is scanned around the boundary. In other embodiments, a light spot is scanned around a substantially annular trajectory radially outward from the pupil. The signals corresponding to the intensity of the reflected light are then processed and measured to determine the eye's position. A flap of tissue covering the boundary may be automatically detected so as to selectively measure the boundary away from the flap. The invention also provides for integrating the eye tracker into a laser eye surgery system.
摘要翻译：提供系统，方法和装置，用于通过跟踪眼睛的边界（例如，白色巩膜和彩色虹膜之间的界面）来导出眼睛的相对位置。用于跟踪患者眼睛位置的技术包括将光引导到巩膜和虹膜之间的眼睛的环形区域并且接收来自该区域的反射光。然后测量反射光的强度以确定眼睛的相对位置。在一些实施例中，测量的区域围绕边界扫描。在其他实施例中，光斑围绕从瞳孔径向向外的基本上环形的轨迹被扫描。然后对与反射光强度相对应的信号进行处理和测量，以确定眼睛的位置。可以自动检测覆盖边界的组织瓣，以便选择性地测量远离瓣的边界。本发明还提供将眼睛跟踪器整合到激光眼睛手术系统中。

2. 发明授权

US08774904B2 Device with an OCT system for examining and treating living tissue by means of heating of the tissue by absorbing electromagnetic radiation 有权
标题翻译：具有OCT系统的装置，用于通过吸收电磁辐射来加热组织来检查和处理活组织
公开(公告)号：US08774904B2
公开(公告)日：2014-07-08
申请号：US13642212
申请日：2011-04-16
申请人： Reginald Birngruber , Ralf Brinkmann , Gereon Huettmann , Heike Mueller
发明人： Reginald Birngruber , Ralf Brinkmann , Gereon Huettmann , Heike Mueller
IPC分类号： A61B6/00
CPC分类号： A61B5/0066 , A61B5/0097 , A61B5/015 , A61B5/05 , A61B5/7225 , A61B5/742 , A61B18/20 , A61B2018/00636 , A61F9/008 , A61N5/00
摘要： A device for examining or treating living tissue by means of local heating of the tissue by absorbing electromagnetic radiation, with at least one radiation source emitting electromagnetic radiation, a control unit for controlling the irradiation parameters of the radiation source, and at least one FD-OCT apparatus with a light source emitting a measurement light for illuminating that tissue region in which the electromagnetic radiation is absorbed by the tissue, characterized by a computational unit for carrying out the following steps: determining the depth-resolved tissue velocity in the radiation direction of the measurement light at a predetermined measurement point of the tissue from the phase information from the FD-OCT interference light, integrating the established tissue velocity over time, differentiating the calculated time integral with respect to space, and displaying the spatial derivative as a function of space and time and/or feeding the spatial derivative as a function of space and time to an evaluation module and/or feeding the spatial derivative as a function of space and time to the control unit.
摘要翻译：一种用于通过吸收电磁辐射的局部加热来检查或处理生物体组织的装置，具有至少一个发射电磁辐射的辐射源，用于控制辐射源的照射参数的控制单元和至少一个FD- OCT装置，具有发射用于照射组织区域的测量光的光源，其中电磁辐射被组织吸收，其特征在于用于执行以下步骤的计算单元：确定辐射方向上的深度分辨组织速度根据来自FD-OCT干涉光的相位信息在组织的预定测量点处的测量光，将所建立的组织速度随时间积分，将所计算的时间积分与空间进行微分，并将空间导数作为空间和时间和/或馈送空间导数作为功能 n到评估模块的空间和时间和/或将空间导数作为空间和时间的函数馈送到控制单元。

3. 发明申请

US20130102894A1 Device With an OCT System for Examining and Treating Living Tissue by Means of Heating of the Tissue by Absorbing Electromagnetic Radiation 有权
标题翻译：具有通过吸收电磁辐射通过组织加热检查和处理生活组织的OCT系统的装置
公开(公告)号：US20130102894A1
公开(公告)日：2013-04-25
申请号：US13642212
申请日：2011-04-16
申请人： Reginald Birngruber , Ralf Brinkmann , Gereon Huettmann , Heike Mueller
发明人： Reginald Birngruber , Ralf Brinkmann , Gereon Huettmann , Heike Mueller
IPC分类号： A61B5/00 , A61N5/00
CPC分类号： A61B5/0066 , A61B5/0097 , A61B5/015 , A61B5/05 , A61B5/7225 , A61B5/742 , A61B18/20 , A61B2018/00636 , A61F9/008 , A61N5/00
摘要： A device for examining or treating living tissue by means of local heating of the tissue by absorbing electromagnetic radiation, with at least one radiation source emitting electromagnetic radiation, a control unit for controlling the irradiation parameters of the radiation source, and at least one FD-OCT apparatus with a light source emitting a measurement light for illuminating that tissue region in which the electromagnetic radiation is absorbed by the tissue, characterized by a computational unit for carrying out the following steps: determining the depth-resolved tissue velocity in the radiation direction of the measurement light at a predetermined measurement point of the tissue from the phase information from the FD-OCT interference light, integrating the established tissue velocity over time, differentiating the calculated time integral with respect to space, and displaying the spatial derivative as a function of space and time and/or feeding the spatial derivative as a function of space and time to an evaluation module and/or feeding the spatial derivative as a function of space and time to the control unit.
摘要翻译：一种用于通过吸收电磁辐射的局部加热来检查或处理生物体组织的装置，具有至少一个发射电磁辐射的辐射源，用于控制辐射源的照射参数的控制单元和至少一个FD- OCT装置，具有发射用于照射组织区域的测量光的光源，其中电磁辐射被组织吸收，其特征在于用于执行以下步骤的计算单元：确定辐射方向上的深度分辨组织速度根据来自FD-OCT干涉光的相位信息在组织的预定测量点处的测量光，将所建立的组织速度随时间积分，将所计算的时间积分与空间进行微分，并将空间导数作为空间和时间和/或馈送空间导数作为功能 n到评估模块的空间和时间和/或将空间导数作为空间和时间的函数馈送到控制单元。

4. 发明授权

US4741612A Device for performing a photocoagulation operation on a biological tissue, especially on the fundus of an eye 失效
标题翻译：用于对生物组织进行光凝固操作的装置，特别是在眼底
公开(公告)号：US4741612A
公开(公告)日：1988-05-03
申请号：US877823
申请日：1986-06-30
申请人： Reginald Birngruber , Veit-Peter Gabel
发明人： Reginald Birngruber , Veit-Peter Gabel
IPC分类号： A61B17/00 , A61B18/20 , A61F9/008 , A61B3/10 , A61B17/36
CPC分类号： A61F9/00821 , A61B18/20 , A61F9/008 , A61F2009/00863
摘要： A control system for use with a conventional photocoagulation device for controlling the exposure parameters of irradiation of biological tissue, such as the fundus of an eye. The photocoagulation device includes a source of radiation, a means for initiating and terminating the source of radiation, and sensing means for measuring the extent of coagulation of the biological tissue. Exposure parameters of the device include exposure time and the wavelength spot size and power of the irradiating beam. The control system cooperates with the device for determining and regulating the exposure parameters in accordance with the unique mathematical relationship between the extent and progression of coagulation during a photocoagulation operation, thereby to terminate the photocoagulation operation should unsatisfactory results be anticipated.
摘要翻译：一种用于常规光凝设备的控制系统，用于控制诸如眼底的生物组织的照射的曝光参数。光凝设备包括辐射源，用于启动和终止辐射源的装置，以及用于测量生物组织凝固程度的感测装置。设备的曝光参数包括曝光时间和照射光束的波长光斑尺寸和光焦度。控制系统与装置配合，以根据光凝固操作期间凝固程度和进展之间的独特数学关系来确定和调节曝光参数，从而如果不能令人满意的结果预期结束，则停止光凝术操作。

5. 发明申请

US20150182166A1 SYSTEM AND METHOD FOR MONITORING AND TREATING A SURFACE OF A SUBJECT 有权
标题翻译：用于监控和处理主体表面的系统和方法
公开(公告)号：US20150182166A1
公开(公告)日：2015-07-02
申请号：US14413571
申请日：2013-07-10
申请人： Conor L. Evans , Gabriela Apiou , Reginald Birngruber , Alexander J. Nichols , Emmanouil Rousakis , Zongxi Li
发明人： Conor L. Evans , Gabriela Apiou , Reginald Birngruber , Alexander J. Nichols , Emmanouil Rousakis , Zongxi Li
IPC分类号： A61B5/00 , A61B19/00 , A61B5/1455
CPC分类号： A61K49/0015 , A61B5/0022 , A61B5/14551 , A61B5/14552 , A61B5/14556 , A61B5/443 , A61B5/4839 , A61B5/6832 , A61B5/6833 , A61B5/743 , A61B90/39 , A61B2562/12 , A61F2013/0097 , C07D487/22
摘要： A system and method are provided for the design and assembly of a device including a sensor capable and a compatible matrix material incorporated into a dressing. The sensor is capable of detecting analytes such as molecular oxygen, carbon dioxide, nitric oxides, dissolved analytes in plasma, and hydrogen ions, and the matrix is at least partially permeable to the analyte. The device emits a detectable signal when the sensor is excited in the presence of the analyte.
摘要翻译：提供了一种系统和方法，用于设计和组装包括传感器能力的装置以及并入敷料中的相容的基质材料。该传感器能够检测分析物，如分子氧，二氧化碳，一氧化氮，等离子体中溶解的分析物和氢离子，基质至少部分可渗透分析物。当传感器在分析物存在下被激发时，该装置发出可检测的信号。

6. 发明授权

US06234633B1 Method for the topographic display of fluorescent interior surfaces 失效
标题翻译：荧光内表面的地形显示方法
公开(公告)号：US06234633B1
公开(公告)日：2001-05-22
申请号：US09431162
申请日：1999-11-01
申请人： Reginald Birngruber , Joachim Noack , Ursula Schmidt-Erfurth
发明人： Reginald Birngruber , Joachim Noack , Ursula Schmidt-Erfurth
IPC分类号： A61B300
CPC分类号： A61B3/1225
摘要： A method for the topographic display of interior surfaces of an object, for example, leakages on vessels of biological material by means of fluorescence angiography, in the case of which fluorescence images are produced in several planes of different depths and a fluorescent segmental chart is obtained therefrom.
摘要翻译：获得物体内表面的地形显示的方法，例如通过荧光血管造影在生物材料的血管上的泄漏，在其中在不同深度的几个平面中产生荧光图像和荧光分段图的情况下由此。

7. 发明授权

US10016164B2 System and method for monitoring and treating a surface of a subject 有权
公开(公告)号：US10016164B2
公开(公告)日：2018-07-10
申请号：US14413571
申请日：2013-07-10
申请人： Conor L. Evans , Gabriela Apiou , Reginald Birngruber , Alexander J. Nichols , Emmanouil Rousakis , Zongxi Li
发明人： Conor L. Evans , Gabriela Apiou , Reginald Birngruber , Alexander J. Nichols , Emmanouil Rousakis , Zongxi Li
IPC分类号： A61B5/1455 , A61B5/00 , A61B90/00 , A61F13/00
CPC分类号： A61K49/0015 , A61B5/0022 , A61B5/14551 , A61B5/14552 , A61B5/14556 , A61B5/443 , A61B5/4839 , A61B5/6833 , A61B5/743 , A61B90/39 , A61B2562/12 , A61F2013/0097 , C07D487/22
摘要： A system and method are provided for the design and assembly of a device including a sensor capable and a compatible matrix material incorporated into a dressing. The sensor is capable of detecting analytes such as molecular oxygen, carbon dioxide, nitric oxides, dissolved analytes in plasma, and hydrogen ions, and the matrix is at least partially permeable to the analyte. The device emits a detectable signal when the sensor is excited in the presence of the analyte.

8. 发明授权

US5302259A Method and apparatus for altering the properties in light absorbing material 失效
标题翻译：用于改变光吸收材料性能的方法和装置
公开(公告)号：US5302259A
公开(公告)日：1994-04-12
申请号：US22773
申请日：1993-02-23
申请人： Reginald Birngruber
发明人： Reginald Birngruber
IPC分类号： A61B17/00 , A61B18/20 , B01J19/12 , G02B6/13 , C25F5/00
CPC分类号： G02B6/13 , A61B18/20 , B01J19/121 , B01J19/122 , A61B2017/00146 , A61B2017/00154 , Y10S204/901
摘要： A method and apparatus are disclosed for altering the properties of light sensitive material, for example, biological material, which has a plurality of randomly spaced light absorbing structures thereon. A beam of light, for example, from a laser, is directed, as by scanning, onto a site of the material to be influenced. In order to achieve changes in the properties of the light sensitive material substantially only at each light absorbing structure, the light beam is modulated with a pattern of successive pulses, the pattern being a plurality of pulses of selected duration, energy level, and repetition frequency. The light induced changes may be thermal, mechanical, or chemical in nature.
摘要翻译：公开了用于改变光敏材料的性质的方法和装置，例如生物材料，其上具有多个随机间隔的光吸收结构。例如，来自激光器的光束通过扫描被引导到待影响的材料的位置上。为了基本上仅在每个光吸收结构处实现光敏材料的性质的变化，光束被连续脉冲的图案调制，该图形是选定持续时间，能级和重复频率的多个脉冲。光诱导的变化本质上可能是热，机械或化学的。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式