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1. 发明申请

US20060020046A1 Compositions comprising lycopene for the treatment and prevention of angiogenesis associated pathologies 审中-公开
标题翻译：包含番茄红素用于治疗和预防血管生成相关病理的组合物
公开(公告)号：US20060020046A1
公开(公告)日：2006-01-26
申请号：US10504829
申请日：2003-02-06
申请人： Regina Goralczyk , Klaus Jung , Michael Lein , Luca Barella , Ulrich Siler , Elisabeth Stocklin , Karin Wertz
发明人： Regina Goralczyk , Klaus Jung , Michael Lein , Luca Barella , Ulrich Siler , Elisabeth Stocklin , Karin Wertz
IPC分类号： A61K31/015 , A61K31/21 , A61K31/7048 , A61K31/7008
CPC分类号： A61K31/05 , A23L33/105 , A23V2002/00 , A61K31/01 , A61K31/015 , A61K31/355 , A61K31/375 , A61K2300/00 , A23V2250/213 , A23V2250/712 , A23V2250/708 , A23V2250/211
摘要： The invention is concerned with the use of lycopene, optionally in combination with vitamin E and/or C or other biologically active ingredients as disclosed in the specification, in the manufacture of a composition for the primary and secondary prevention of angiogenesis-associated pathologies and coadjuvant treatment thereof; as well as with particular novel formulations comprising lycopene.
摘要翻译：本发明涉及使用番茄红素，任选地与维生素E和/或C或本说明书中公开的其它生物活性成分组合，用于制备用于一级和二级预防血管生成相关病理学和辅助剂的组合物治疗; 以及包含番茄红素的特定新型制剂。

2. 发明申请

US20090326056A1 NOVEL ACTIVES AGAINST PROSTATE CARCINOMA 审中-公开
标题翻译：对前瞻性癌症的新兴活动
公开(公告)号：US20090326056A1
公开(公告)日：2009-12-31
申请号：US12299825
申请日：2007-05-15
申请人： Regina Goralczyk , Ulrich Siler , Karin Wertz
发明人： Regina Goralczyk , Ulrich Siler , Karin Wertz
IPC分类号： A61K31/352
CPC分类号： A61K31/01 , A61K31/353 , A61K31/355 , A61K2300/00
摘要： The present invention relates to the use of a composition comprising lycopene and genistein in the prevention and coadjuvant treatment of prostate carcinoma. The present invention is also directed to the use of a composition comprising lycopene and epigallocatechin gallate in the prevention and coadjuvant treatment of prostate carcinoma. More specifically, the present invention relates to the use of one of these compositions in the primary prevention (i.e., the prophylactic supplementation of healthy subjects) of the onset of prostate carcinoma, in the coadjuvant treatment (i.e. the supplementation accompanying a running therapy of prostate carcinoma) and in the secondary prevention (i.e., the supplementation after a successful therapy for the prevention of relapse) of prostate carcinoma. Furthermore, the present invention is also directed to the reduction/decrease of the PSA plasma level in the blood of subjects to whom either a composition comprising lycopene and genistein or to whom either a composition comprising lycopene and epigallocatechin gallate are administered. Further compounds that may preferably also be present in the composition of the present invention are vitamin E, resveratrol and polyunsaturated fatty acid (derivative)s.
摘要翻译：本发明涉及包含番茄红素和染料木素的组合物在预防和辅助治疗前列腺癌中的用途。本发明还涉及包含番茄红素和表没食子儿茶素没食子酸酯的组合物在预防和辅助治疗前列腺癌中的用途。更具体地说，本发明涉及这些组合物中的一种在辅助治疗中的一级预防（即健康受试者的预防性补充）前列腺癌发作的用途（即伴随前列腺的运行治疗的补充）癌症）和前列腺癌的二次预防（即成功治疗预防复发后的补充）。此外，本发明还涉及给予包含番茄红素和染料木素的组合物或包含番茄红素和表没食子儿茶素没食子酸酯的组合物的受试者的血液中PSA血浆水平的降低/降低。还可以存在于本发明组合物中的其它化合物是维生素E，白藜芦醇和多不饱和脂肪酸（衍生物）。

3. 发明申请

US20060069151A1 Novel use of lycopene 审中-公开
标题翻译：小说使用番茄红素
公开(公告)号：US20060069151A1
公开(公告)日：2006-03-30
申请号：US10537452
申请日：2003-12-04
申请人： Luca Barella , Regina Goralczyk , Ulrich Siler , Karin Wertz
发明人： Luca Barella , Regina Goralczyk , Ulrich Siler , Karin Wertz
IPC分类号： A61K31/375 , A61K31/355 , A61K31/353 , A61K31/015
CPC分类号： A61K31/355 , A61K31/01 , A61K31/375 , A61K2300/00
摘要： Lycopene can be used in the primary prevention and incidence risk reduction of non-cancerous symptoms and/or pathologies (i.e., the prophylactic supplementation of the healthy subjects), in the treatment or the coadjuvant treatment of non-can-cerous symptoms and/or pathologies (i.e. the supplementation as therapy or accompanying a running therapy) and in the secondary prevention of non-cancerous symptoms and/or pahtologies (i.e., the supplementation after a successful therapy for the prevention of the relapse), which are associated with, favored by or caused by androgen signalling or which are sensitive to a reduction of androgen signalling.
摘要翻译：番茄红素可用于非癌症症状和/或非癌症症状的治疗或辅助治疗中非癌症症状和/或病态（即健康受试者的预防性补充）的一级预防和发病风险降低病理学（即作为治疗或伴随运行疗法的补充剂）和二次预防非癌症症状和/或睑炎（即，成功治疗以后用于预防复发的补充剂）与青睐相关由雄激素信号传导或由其引起，或对雄激素信号传导的降低敏感。

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