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1. 发明授权

US06643545B2 Method and apparatus for delivering an optimum shock duration in treating cardiac arrhythmias 失效
标题翻译：用于在治疗心律失常中提供最佳休克持续时间的方法和装置
公开(公告)号：US06643545B2
公开(公告)日：2003-11-04
申请号：US09915898
申请日：2001-07-26
申请人： Raymond E. Ideker , Gregory P. Walcott , Stephen J. Hahn
发明人： Raymond E. Ideker , Gregory P. Walcott , Stephen J. Hahn
IPC分类号： A61N139
CPC分类号： A61N1/3937
摘要： The present invention provides apparatus and methods for delivering an optimum electrical shock in treating cardiac arrhythmias. The apparatus comprises means for producing an electrical waveform signal at least two electrodes The voltage or current of the signal is then detected to determine the signal time constant. The signal time constant is then used in conjunction with a model time constant to determine when the peak amplitude is reached. The waveform is then interrupted when the peak amplitude is reached. Also provided are methods of selecting a cardiac defibrillator by measuring the impedance of implanted electrodes and then selecting a defibrillator having a capacitor which provides an RC time constant equal to that of a model time constant.
摘要翻译：本发明提供了用于在治疗心律失常中递送最佳电击的装置和方法。该装置包括用于在至少两个电极产生电波形信号的装置。然后检测信号的电压或电流以确定信号时间常数。然后将信号时间常数与模型时间常数结合使用以确定何时达到峰值振幅。当达到峰值振幅时，波形中断。还提供了通过测量注入电极的阻抗然后选择具有提供等于模型时间常数的RC时间常数的电容器的除颤器来选择心脏除颤器的方法。

2. 发明授权

US5540723A Method and apparatus for delivering an optimum shock duration in treating cardiac arrhythmias 失效
标题翻译：用于在治疗心律失常中提供最佳休克持续时间的方法和装置
公开(公告)号：US5540723A
公开(公告)日：1996-07-30
申请号：US132373
申请日：1993-10-06
申请人： Raymond E. Ideker , Gregory P. Walcott , Stephen J. Hahn
发明人： Raymond E. Ideker , Gregory P. Walcott , Stephen J. Hahn
IPC分类号： A61N1/39
CPC分类号： A61N1/3937
摘要： The present invention provides apparatus and methods for delivering an optimum electrical shock in treating cardiac arrhythmias. The invention comprises apparatus for producing an electrical waveform signal at least at two electrodes. The voltage or current of the signal is then detected to determine the signal time constant. The signal time constant is then used in conjunction with a model time constant to determine when the peak amplitude is reached. The waveform is then interrupted when the peak amplitude is reached. Also provided are methods of selecting a cardiac defibrillator by measuring the impedance of implanted electrodes and then selecting a defibrillator having a capacitor which provides an RC time constant equal to that of a model time constant.
摘要翻译：本发明提供了用于在治疗心律失常中递送最佳电击的装置和方法。本发明包括至少在两个电极产生电波形信号的装置。然后检测信号的电压或电流以确定信号时间常数。然后将信号时间常数与模型时间常数结合使用以确定何时达到峰值振幅。当达到峰值振幅时，波形中断。还提供了通过测量注入电极的阻抗然后选择具有提供等于模型时间常数的RC时间常数的电容器的除颤器来选择心脏除颤器的方法。

3. 发明授权

US06556865B2 Method for improving cardiac function following delivery of a defibrillation shock 有权
公开(公告)号：US06556865B2
公开(公告)日：2003-04-29
申请号：US09772225
申请日：2001-01-29
申请人： Gregory P. Walcott , Fred William Chapman , Raymond E. Ideker
发明人： Gregory P. Walcott , Fred William Chapman , Raymond E. Ideker
IPC分类号： A61N139
CPC分类号： A61N1/3962
摘要： A method of reducing the likelihood of pulseless electrical activity (PEA) after defibrillation in a subject comprises administering to a subject afflicted with fibrillation a first treatment waveform, the first treatment waveform insufficient to defibrillate the heart; and then administering to the subject a second treatment waveform that defibrillates the heart and restores organized electrical activity in the heart. The first treatment waveform reduces the likelihood of onset of PEA following the second treatment waveform, as compared to that likelihood which would be present in the absence of the first treatment waveform.

4. 发明授权

US5222501A Methods for the diagnosis and ablation treatment of ventricular tachycardia 失效
标题翻译：室性心动过速的诊断和消融治疗方法
公开(公告)号：US5222501A
公开(公告)日：1993-06-29
申请号：US829457
申请日：1992-01-31
申请人： Raymond E. Ideker , Gregory P. Walcott
发明人： Raymond E. Ideker , Gregory P. Walcott
IPC分类号： A61B18/20 , A61B5/0464 , A61B8/12 , A61B17/00 , A61B17/22 , A61B17/32 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/24 , A61N1/05
CPC分类号： A61B8/12 , A61B18/1492 , A61B5/0464 , A61N1/056 , A61B17/22012 , A61B18/082 , A61B18/14 , A61B18/18 , A61B18/24 , A61B2017/00243 , A61B2017/00292
摘要： A closed-heart method for treating ventricular tachycardia in a myocardial infarct patient afflicted with ventricular tachycardia is disclosed. The method comprises, first, defining a thin layer of spared myocardial tissue positioned between the myocardial infarct scar tissue and the inner surface of the myocardium (the endocardium) of the patient, and then ablating the thin layer of spared myocardial tissue by a closed-heart procedure with an ablation catheter. Apparatus for carrying out the method is also disclosed.Also disclosed is a method for prognosing the likelihood of ventricular tachycardia occuring in a myocardial infarct patient not previously diagnosed as afflicted with ventricular tachycardia. The method comprises detecting a thin layer of spared myocardial tissue positioned between the myocardial infarct scar tissue and the inner surface of the myocardium (the endocardium) in the patient.
摘要翻译：公开了一种用于治疗患有心室心动过速的心肌梗死患者的室性心动过速的闭心方法。该方法包括：首先定义位于心肌梗塞瘢痕组织和患者心肌（内膜）内表面之间的剩余心肌组织的薄层，然后通过封闭的心脏组织切除稀释的心肌组织薄层，心脏手术与消融导管。还公开了用于执行该方法的装置。还公开了一种预测在以前未被诊断为患有心室性心动过速的心肌梗塞患者中发生的室性心动过速的可能性的方法。该方法包括检测位于心肌梗塞瘢痕组织和患者心肌（内心膜）内表面之间的休息心肌组织薄层。

5. 发明授权

US08843195B2 Methods, systems and computer program products to inhibit ventricular fibrillation during cardiopulmonary resuscitation 有权
标题翻译：方法，系统和计算机程序产品在心肺复苏期间抑制心室颤动
公开(公告)号：US08843195B2
公开(公告)日：2014-09-23
申请号：US12766290
申请日：2010-04-23
申请人： Raymond E. Ideker , Gregory P. Walcott
发明人： Raymond E. Ideker , Gregory P. Walcott
IPC分类号： A61N1/39
CPC分类号： A61N1/39 , A61H31/00 , A61H31/005 , A61H31/006 , A61H31/007 , A61H2201/10 , A61H2201/5007 , A61H2201/5043 , A61H2201/5048 , A61H2201/5058 , A61H2203/03 , A61H2230/04
摘要： Methods, systems and computer program products determine and identify a favorable time to deliver cardiac compression to a subject to avoid a vulnerable period of a spontaneous intrinsic cardiac cycle.
摘要翻译：方法，系统和计算机程序产品确定并确定向对象递送心脏压缩的有利时间，以避免自发内在心脏周期的脆弱时期。

6. 发明申请

US20100204623A1 Methods, Systems and Computer Program Products to Inhibit Ventricular Fibrillation During Cardiopulmonary Resuscitation 有权
标题翻译：方法，系统和计算机程序产品在心肺复苏期间抑制心室纤颤
公开(公告)号：US20100204623A1
公开(公告)日：2010-08-12
申请号：US12766290
申请日：2010-04-23
申请人： Raymond E. Ideker , Gregory P. Walcott
发明人： Raymond E. Ideker , Gregory P. Walcott
IPC分类号： A61H31/00 , A61N1/00
CPC分类号： A61N1/39 , A61H31/00 , A61H31/005 , A61H31/006 , A61H31/007 , A61H2201/10 , A61H2201/5007 , A61H2201/5043 , A61H2201/5048 , A61H2201/5058 , A61H2203/03 , A61H2230/04
摘要： Methods, systems and computer program products determine and identify a favorable time to deliver cardiac compression to a subject to avoid a vulnerable period of a spontaneous intrinsic cardiac cycle.
摘要翻译：方法，系统和计算机程序产品确定并确定向对象递送心脏压缩的有利时间，以避免自发内在心脏周期的脆弱时期。

7. 发明授权

US6006131A Dual current pathway atrial defibrillation apparatus 失效
标题翻译：双通道心房除颤装置
公开(公告)号：US6006131A
公开(公告)日：1999-12-21
申请号：US700694
申请日：1996-08-13
申请人： Randolph A. Cooper , Raymond E. Ideker , Gregory P. Walcott
发明人： Randolph A. Cooper , Raymond E. Ideker , Gregory P. Walcott
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3918 , A61N1/395
摘要： An implantable system for the defibrillation of the atria of a patient's heart includes a first pair of atrial defibrillation electrodes configured for delivering a first atrial defibrillation pulse along a first current pathway in the heart, and a pulse generator operatively associated with the first pair of atrial defibrillation electrodes for delivering the first atrial defibrillation pulse. A second pair of atrial defibrillation electrodes configured for delivering a second atrial defibrillation pulse along a second current pathway in the heart is also included, with the second current pathway being different from the first current pathway. A pulse generator is operatively associated with the second pair of atrial defibrillation electrodes for delivering the second atrial defibrillation pulse after the first defibrillation pulse.
摘要翻译：用于对患者心脏的心房进行除颤的可植入系统包括：第一对心房除颤电极，其被配置为沿着心脏中的第一电流通路输送第一心房除颤脉冲;以及脉冲发生器，其与第一对心房用于递送第一心房除颤脉冲的除颤电极。还包括第二对心房除颤电极，其被配置用于沿着心脏中的第二电流通路递送第二心房除颤脉冲，其中第二电流通路不同于第一电流通路。脉冲发生器可操作地与第二对心房除颤电极相关联，用于在第一除颤脉冲之后输送第二心房除颤脉冲。

8. 发明授权

US5997526A Shape memory catheter 失效
标题翻译：形状记忆导管
公开(公告)号：US5997526A
公开(公告)日：1999-12-07
申请号：US621232
申请日：1996-03-25
申请人： Jeffrey J. Giba , Gregory P. Walcott , Raymond E. Ideker , Donald A. Richardson
发明人： Jeffrey J. Giba , Gregory P. Walcott , Raymond E. Ideker , Donald A. Richardson
IPC分类号： A61M25/00 , A61M25/01 , A61M25/16
CPC分类号： A61M25/0041 , A61M25/0043 , A61B2018/00916 , A61M25/0158 , Y10T29/49865
摘要： A conformable catheter comprising a catheter handle, an elongated catheter tube, and a distal tip portion of the catheter tube, capable of assuming a desired pre-programmed shape. A wire member is disposed within the core of the catheter's tip portion and is formed of a material, such as, for example, a shape-memory binary nickel-titanium alloy, that will assume a pre-programmed shape after pre-shaping, heat treatment, cooling and subsequent heating. To pre-program the shape of the wire member, prior to assembly of the catheter, the wire member is wound around a shaped, heat resistant fixture, heated until the temperature of the wire member exceeds the temperature at which the shape of the wire member on the fixture becomes programmed into the wire member, and cooled. Upon subsequent heating of the wire member above its activation temperature after inclusion of the wire member into the catheter tubing, such as by controllably connecting the wire member to an electrical power source, the wire member, and thus the catheter's tip portion, assumes the pre-programmed curved or bent shape from its normally straight, generally linear disposition.
摘要翻译：包括导管手柄，细长导管管和导管管的远端尖端部分的适形导管能够呈现所需的预编程形状。线构件设置在导管的尖端部分的芯部内，并且由诸如例如形状记忆二元镍钛合金的材料形成，其将在预成形之后呈现预编程形状，热量处理，冷却和随后的加热。为了对线材的形状进行预编程，在组装导管之前，将线材卷绕在成形的耐热夹具上，加热直到线材的温度超过线材的形状的温度在夹具上编程成线材，并冷却。在将线构件插入导管中之后，例如通过将线构件可控地连接到电源上，随后将丝线构件加热到其活化温度以上，线构件以及因此导管的尖端部分呈现预先编程的弯曲或弯曲形状从其通常的直线，大致线性的布置。

9. 发明授权

US07734344B2 Methods, systems and computer program products to inhibit ventricular fibrillation during cardiopulmonary resuscitation 有权
标题翻译：方法，系统和计算机程序产品在心肺复苏期间抑制心室颤动
公开(公告)号：US07734344B2
公开(公告)日：2010-06-08
申请号：US10727123
申请日：2003-12-02
申请人： Raymond E. Ideker , Gregory P. Walcott
发明人： Raymond E. Ideker , Gregory P. Walcott
IPC分类号： A61N1/39
CPC分类号： A61N1/39 , A61H31/00 , A61H31/005 , A61H31/006 , A61H31/007 , A61H2201/10 , A61H2201/5007 , A61H2201/5043 , A61H2201/5048 , A61H2201/5058 , A61H2203/03 , A61H2230/04
摘要： Methods, systems and computer program products determine and identify a favorable time to deliver cardiac compression to a subject to avoid a vulnerable period of a spontaneous intrinsic cardiac cycle.
摘要翻译：方法，系统和计算机程序产品确定并确定向对象递送心脏压缩的有利时间，以避免自发内在心脏周期的脆弱时期。

10. 发明授权

US07162298B2 Devices for detecting the presence of cardiac activity following administration of defibrillation therapy 有权
标题翻译：用于在除颤治疗后检测心脏活动的存在的装置
公开(公告)号：US07162298B2
公开(公告)日：2007-01-09
申请号：US10238340
申请日：2002-09-10
申请人： Raymond E. Ideker , Gregory P. Walcott
发明人： Raymond E. Ideker , Gregory P. Walcott
IPC分类号： A61N1/39
CPC分类号： A61N1/3925
摘要： The present invention provides systems, methods and computer program products for detecting the presence of cardiac activity in a patient. The present invention includes a detector circuit that is configured to detect the influence of a first defibrillation shock on the patient immediately subsequent to termination of a first defibrillation shock.
摘要翻译：本发明提供用于检测患者心脏活动的存在的系统，方法和计算机程序产品。本发明包括检测器电路，其被配置为在第一除颤电击结束之后立即检测第一除颤电击对患者的影响。

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