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1. 发明申请

US20060041278A1 Automatic defibrillator module for integration with standard patient monitoring equipment 审中-公开
公开(公告)号：US20060041278A1
公开(公告)日：2006-02-23
申请号：US11180396
申请日：2005-07-13
申请人： Raymond Cohen , Dongping Lin , Mike Norton , Patrick Bradley , Gary Mezack , David Clark
发明人： Raymond Cohen , Dongping Lin , Mike Norton , Patrick Bradley , Gary Mezack , David Clark
IPC分类号： A61N1/39
CPC分类号： A61N1/39 , A61N1/3925
摘要： A defibrillator module is described which includes a cardiac sensor, a pulse generator and a controller that generates commands responsive to intrinsic cardiac signals for the operation of said pulse generator. The defibrillator module synergistic and arranged so that it can be coupled to a generic patient monitor so that the two can share certain functions. For example, operational parameters and other signals indicative of the operation of the defibrillator module can be shown to the clinician by the patient monitor. Data between the defibrillator module and the patient monitor is exchanged using either a standard or a customized protocol.

2. 发明授权

US07006865B1 Automatic defibrillator module for integration with standard patient monitoring equipment 失效
标题翻译：自动除颤器模块，用于与标准的患者监测设备集成
公开(公告)号：US07006865B1
公开(公告)日：2006-02-28
申请号：US09523912
申请日：2000-03-09
申请人： Raymond W. Cohen , Dongping Lin , Mike Norton , Patrick Bradley , Gary Mezack , David Clark
发明人： Raymond W. Cohen , Dongping Lin , Mike Norton , Patrick Bradley , Gary Mezack , David Clark
IPC分类号： A61N1/40
CPC分类号： A61N1/39 , A61N1/3925
摘要： A defibrillator module is described which includes a cardiac sensor, a pulse generator and a controller that generates commands responsive to intrinsic cardiac signals for the operation of said pulse generator. The defibrillator module synergistic and arranged so that it can be coupled to a generic patient monitor so that the two can share certain functions. For example, operational parameters and other signals indicative of the operation of the defibrillator module can be shown to the clinician by the patient monitor. Data between the defibrillator module and the patient monitor is exchanged using either a standard or a customized protocol.
摘要翻译：描述了除颤器模块，其包括心脏传感器，脉冲发生器和控制器，其产生响应于内部心脏信号用于所述脉冲发生器的操作的命令。除颤器模块协同和布置，使得其可以耦合到通用的患者监护仪，使得两者可以共享某些功能。例如，可以由患者监视器向临床医生显示指示除颤器模块的操作的操作参数和其它信号。除颤器模块和患者监护仪之间的数据使用标准或定制协议进行交换。

3. 发明申请

US20090131997A1 AUTOMATIC DEFIBRILLATOR MODULE FOR INTEGRATION WITH STANDARD PATIENT MONITORING EQUIPMENT 审中-公开
标题翻译：用于整合标准患者监测设备的自动消除器模块
公开(公告)号：US20090131997A1
公开(公告)日：2009-05-21
申请号：US12326685
申请日：2008-12-02
申请人： Raymond W. Cohen , Dongping Lin , Mike Norton , Patrick Bradley , Gary Mezack , David Clark
发明人： Raymond W. Cohen , Dongping Lin , Mike Norton , Patrick Bradley , Gary Mezack , David Clark
IPC分类号： A61N1/365 , A61B5/0402
CPC分类号： A61N1/39 , A61N1/3925
摘要： A defibrillator module is described which includes a cardiac sensor, a pulse generator and a controller that generates commands responsive to intrinsic cardiac signals for the operation of said pulse generator. The defibrillator module synergistic and arranged so that it can be coupled to a generic patient monitor so that the two can share certain functions. For example, operational parameters and other signals indicative of the operation of the defibrillator module can be shown to the clinician by the patient monitor. Data between the defibrillator module and the patient monitor is exchanged using either a standard or a customized protocol.
摘要翻译：描述了除颤器模块，其包括心脏传感器，脉冲发生器和控制器，其产生响应于内部心脏信号用于所述脉冲发生器的操作的命令。除颤器模块协同和布置，使得其可以耦合到通用的患者监护仪，使得两者可以共享某些功能。例如，可以由患者监视器向临床医生显示指示除颤器模块的操作的操作参数和其它信号。除颤器模块和患者监护仪之间的数据使用标准或定制协议进行交换。

4. 发明授权

US08515529B2 Detecting sleep disorders using heart activity 有权
标题翻译：使用心脏活动检测睡眠障碍
公开(公告)号：US08515529B2
公开(公告)日：2013-08-20
申请号：US12370090
申请日：2009-02-12
申请人： Yachuan Pu , Charles Gropper , Dongping Lin
发明人： Yachuan Pu , Charles Gropper , Dongping Lin
IPC分类号： A61B5/04
CPC分类号： A61B5/4818 , A61B5/0022 , A61B5/02405 , A61B5/02438 , A61B5/0402 , A61B5/0464 , A61B5/11 , A61B5/4806 , A61B5/7207 , A61B5/7264
摘要： Systems, methods, apparatus, and computer program products for detecting the existence of a sleep disorder in an individual using heart activity. In one aspect, machine-implemented methods include the actions of analyzing a machine-readable heart rate series of a monitored individual in the time domain using one or more digital data processing devices, detecting a cyclic variation in heart rate in the heart rate series as a result of the analysis in the time domain, and outputting, over an output, a report characterizing a sleep disorder event based on the detection of the cyclic variation in heart rate in the heart rate series. The cyclic variation in heart rate is indicative of a sleep disorder.
摘要翻译：用于使用心脏活动来检测个体中睡眠障碍的存在的系统，方法，装置和计算机程序产品。在一个方面，机器实现的方法包括使用一个或多个数字数据处理设备分析在时域中监视的个体的机读可读心率系列的动作，检测心率系列中心率的循环变化作为在时域中进行分析的结果，并且通过输出，基于心率序列中的心率的循环变化的检测，输出表征睡眠障碍事件的报告。心率的循环变化表示睡眠障碍。

5. 发明授权

US06490478B1 System and method for complexity analysis-based cardiac tachyarrhythmia detection 有权
标题翻译：基于复杂性分析的心脏快速性心律失常检测系统与方法
公开(公告)号：US06490478B1
公开(公告)日：2002-12-03
申请号：US09669020
申请日：2000-09-25
申请人： Xu-Sheng Zhang , Dongping Lin
发明人： Xu-Sheng Zhang , Dongping Lin
IPC分类号： A61B50464
CPC分类号： A61N1/39 , A61N1/362 , A61N1/36514 , A61N1/395 , A61N1/3956
摘要： A system and method based on electrocardiogram (ECG) complexity analysis for real-time detecting shockable ventricular fibrillation (VF) and ventricular tachycardia (VT), and discriminating them from non-shockable tachyarrhythmia (e.g. supraventricular tachycardia (SVT) and atrial fibrillation (AF)) and high-frequency noise. In the disclosed invention, complexity measure CM (0 to 100), quantitatively characterizing the complexity nature of the non-linear dynamics underlying cardiac arrhythmia, is extracted from the sensed patient ECG signal using ECG complexity analysis. From the calculated complexity measure, by three thresholds (low complexity threshold (LCT), mediate complexity threshold (MCT), and high complexity threshold (HCT)), different kinds of tachyarrhythmia (i.e. heart rate (HR) above a preset rate threshold) and high-frequency noise are discriminated from each other: for non-shockable tachyarrhythmia, CM≦LCT; for VT, LCT
摘要翻译：一种基于心电图（ECG）复杂度分析的系统和方法，用于实时检测可震颤性心室颤动（VF）和室性心动过速（VT），并将其与不可震颤的快速性心律失常（例如室上性心动过速（SVT）和心房颤动（AF）））和高频噪声。在所公开的发明中，使用ECG复杂性分析从感测的患者ECG信号中提取定量表征心律不齐的非线性动力学的复杂性的复杂度测量CM（0至100）。从计算的复杂度测量中，通过三个阈值（低复杂度阈值（LCT），中介复杂度阈值（MCT）和高复杂度阈值（HCT）），不同种类的快速性心律失常（即高于预设速率阈值的心率（HR）），并且高频噪声彼此区分：对于不可震荡的快速性心律失常，CM <= LCT; 对于VT，LCT

6. 发明授权

US06480734B1 Cardiac arrhythmia detector using ECG waveform-factor and its irregularity 有权
标题翻译：心律失常检测器采用ECG波形因子及其不规则
公开(公告)号：US06480734B1
公开(公告)日：2002-11-12
申请号：US09609558
申请日：2000-06-30
申请人： Xu-Sheng Zhang , Dongping Lin
发明人： Xu-Sheng Zhang , Dongping Lin
IPC分类号： A61B504
CPC分类号： A61N1/39 , A61B5/046 , A61B5/0464 , A61N1/36514 , A61N1/3925 , A61N1/395 , A61N1/3956
摘要： A cardiac monitor is provided that monitors the condition of the heart of a cardiac patient and generates signals indicating one of several conditions, such as supraventricular tachycardia, ventricular tachycardia and ventricular fibrillation. In order to generate these signals, the ECG from the patient is analyzed to determine a cardiac interval and heart rate, as well as a waveform factor and a waveform factor irregularity. The waveform factor is derived from the average of the ECG amplitudes during a cardiac interval and the peak value of the ECG during the same interval. Preferably, a running average is calculated over several intervals. This waveform factor is then used to detect shockable ventricular arrhythmia. The waveform factor irregularity is indicative of the variability of the waveform factor and is used to differentiate between ventricular tachycardia and ventricular defibrillation.
摘要翻译：提供了一种监测心脏病患者心脏状态的心脏监测器，并产生指示若干情况之一的信号，例如室上性心动过速，室性心动过速和心室颤动。为了产生这些信号，分析来自患者的ECG以确定心脏间隔和心率，以及波形因子和波形因子不规则性。波形因子来自心脏间隔期间的ECG幅度的平均值，以及在相同间隔期间的ECG的峰值。优选地，在几个间隔上计算运行平均值。然后将该波形因子用于检测可震荡的室性心律失常。波形因子不规则表示波形因子的变异性，用于区分室性心动过速和心室除颤。

7. 发明授权

US06246907B1 Automatic external cardioverter/defibrillator with cardiac rate detector and method of operating the same 有权
标题翻译：具有心率检测器的自动外部心律转复/除纤颤器及其操作方法
公开(公告)号：US06246907B1
公开(公告)日：2001-06-12
申请号：US09452496
申请日：1999-12-01
申请人： Dongping Lin , Raul Ybarra , Prabodh Mathur
发明人： Dongping Lin , Raul Ybarra , Prabodh Mathur
IPC分类号： A61N139
CPC分类号： A61B5/0464 , A61B5/0456 , A61N1/3925
摘要： An external defibrillator includes a detector used to detect a life threatening condition of a patient, a controller operating the defibrillator automatically and a therapy delivery circuit that delivers appropriate therapy. The defibrillator is attached to a patient and is adapted to monitor the patient and when a life threatening condition is detected, to apply therapy automatically. An averaging scheme is used to determine a current cardiac rate by taking a first average of the intervals between a preset number of successive cardiac events, establishing a differential between this average and the intervals, dropping the interval corresponding to the largest differential. In this manner, the effects of over- and undersensing are eliminated or at least reduced.
摘要翻译：外部除颤器包括用于检测患者的危及生命的状况的检测器，自动地操作除颤器的控制器和递送适当治疗的治疗传递电路。除颤器连接到患者身上，适用于监测患者，何时检测出危及生命的状况，自动进行治疗。平均方案用于通过取预设数量的连续心脏事件之间的间隔的第一平均值来确定当前心率，建立该平均值和间隔之间的差值，丢弃对应于最大差异的间隔。以这种方式，消除或至少减少过度和不足的影响。

8. 发明授权

US09655518B2 Ambulatory and centralized processing of a physiological signal 有权
公开(公告)号：US09655518B2
公开(公告)日：2017-05-23
申请号：US12413290
申请日：2009-03-27
申请人： Dongping Lin
发明人： Dongping Lin
IPC分类号： A61B5/0452 , A61B5/00
CPC分类号： A61B5/0002 , G06F19/00
摘要： A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.

9. 发明授权

US08200319B2 Locating fiducial points in a physiological signal 有权
标题翻译：在生理信号中定位基准点
公开(公告)号：US08200319B2
公开(公告)日：2012-06-12
申请号：US12368976
申请日：2009-02-10
申请人： Yachuan Pu , Charles Gropper , Dongping Lin
发明人： Yachuan Pu , Charles Gropper , Dongping Lin
IPC分类号： A61B5/0402
CPC分类号： A61B5/0452 , A61B5/0402 , A61B5/7253
摘要： Systems, devices, methods, and techniques relating to the identification of fiducial points. In one aspect, a machine implemented method includes obtaining a first time varying physiological signal and a second time varying physiological signal that relate to biological activity of an organism, the first time varying physiological signal and the second time varying physiological signal forming an analytic pair wherein the analytic pair has a time varying phase angle, defining a reference line by a lower boundary of a representation of the time varying phase angle with respect to a time period, and identifying a fiducial point based on the reference line.
摘要翻译：与识别基准点相关的系统，设备，方法和技术。一方面，机器实现的方法包括获得与生物体的生物活性相关的第一时变生理信号和第二时变生理信号，第一时变生理信号和形成分析对的第二时变生理信号，其中分析对具有时变相位角，通过相对于时间段的时变相位角的表示的下边界来定义参考线，以及基于参考线识别基准点。

10. 发明授权

US06993386B2 Public access defibrillator 有权
公开(公告)号：US06993386B2
公开(公告)日：2006-01-31
申请号：US10688362
申请日：2003-10-16
申请人： Dongping Lin , Prabodh Mathur , Raul Ybarra
发明人： Dongping Lin , Prabodh Mathur , Raul Ybarra
IPC分类号： A61N1/39
CPC分类号： A61N1/39
摘要： A publically available external defibrillator includes a detector used to detect a life threatening condition of a patient, a controller operating the defibrillator automatically and a therapy delivery circuit that delivers appropriate therapy. The defibrillator is attached to a patient by any attendant or bystander and once it is attached, the defibrillator is adapted to monitor the patient and when a life threatening condition is detected, to apply therapy automatically, i.e., without any involvement by the patient or the attendant.

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