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1. 发明授权

US07025253B2 Method of examining an object by means of elastography 失效
标题翻译：通过弹性成像检查物体的方法
公开(公告)号：US07025253B2
公开(公告)日：2006-04-11
申请号：US10506456
申请日：2003-02-26
申请人： Ralph Sinkus , Steffen Weiss
发明人： Ralph Sinkus , Steffen Weiss
IPC分类号： G01V3/00
CPC分类号： G01R33/56358 , A61B5/0051 , A61B5/055
摘要： In a method of elastography, diagnostic performance is improved in that the variation in time of the excursion whereby a region responds to excitation by mechanical oscillations is analyzed and the non-linear distortions are measured. Such non-linear distortions are a measure of the non-linear elastic properties of the region and constitute a diagnostically relevant item of information.
摘要翻译：在弹性成像方法中，诊断性能得到改善，分析了区域响应于机械振荡激发的偏移时间的变化，并测量了非线性失真。这种非线性失真是对该区域的非线性弹性特性的度量，并构成了诊断上相关的信息项。

2. 发明申请

US20060258934A1 Magnetic resonance locating method 审中-公开
标题翻译：磁共振定位方法
公开(公告)号：US20060258934A1
公开(公告)日：2006-11-16
申请号：US10554307
申请日：2004-04-13
申请人： Michael Zenge , Steffen Weiss , Tobias Schaeffter , Ralph Sinkus
发明人： Michael Zenge , Steffen Weiss , Tobias Schaeffter , Ralph Sinkus
IPC分类号： A61B5/05
CPC分类号： G01R33/286
摘要： The invention relates to a magnetic resonance method for locating interventional devices, in particular in vivo, in which the interventional device bears a marking which in magnetic resonance images influences the measured signals or generates its own measured signals, where the measured signals are processed by means of a one-dimensional signal processing method in order to suppress noise and artefacts. This may in particular be the maximum entropy method, which can be further expanded by the use of model functions. These model functions are subtracted from the measured signals during the iterative method in order in this way to additionally improve the elimination of artefacts. As an alternative to the use of the maximum entropy method, the use of filters, in particular Wiener filters or bandpass filters, is also possible.
摘要翻译：本发明涉及用于定位介入装置，特别是体内的磁共振方法，其中介入装置具有在磁共振图像中影响测量信号或产生其自身测量信号的标记，其中测量信号通过装置的一维信号处理方法，以便抑制噪声和伪影。这可能特别是最大熵方法，可以通过使用模型函数进一步扩展。在迭代方法中，从测量信号中减去这些模型函数，以此方式另外提高了人为因素的消除。作为使用最大熵方法的替代方案，也可以使用滤波器，特别是维纳滤波器或带通滤波器。

3. 发明申请

US20050104588A1 Method of examing an object by means of elastography 失效
标题翻译：通过弹性成像检查物体的方法
公开(公告)号：US20050104588A1
公开(公告)日：2005-05-19
申请号：US10506456
申请日：2003-02-26
申请人： Ralph Sinkus , Steffen Weiss
发明人： Ralph Sinkus , Steffen Weiss
IPC分类号： G01R33/28 , A61B5/055 , G01R33/563 , G01V3/00
CPC分类号： G01R33/56358 , A61B5/0051 , A61B5/055
摘要： The invention relates to a method of elastography whose diagnostic performance is improved in that the variation in time of the excursion whereby a region responds to excitation by mechanical oscillations is analyzed and the non-linear distortions are measured. Such distortions are a measure of the non-linear elastic properties of the region and constitute a diagnostically relevant item of information.
摘要翻译：本发明涉及一种弹性成像方法，其诊断性能得到改善，分析了区域对机械振荡对激发作出反应的偏移时间的变化，并测量了非线性失真。这种扭曲是衡量该地区的非线性弹性性质，并构成了诊断上相关的信息项目。

4. 发明授权

US09968277B2 Magnetic resonance guidance of a shaft to a target zone 有权
公开(公告)号：US09968277B2
公开(公告)日：2018-05-15
申请号：US14007990
申请日：2012-04-04
申请人： Steffen Weiss , Ronaldus Frederik Johannes Holthuizen , Sascha Krueger , Peter Koken , Daniel Wirtz , Thomas Erik Amthor , Falk Uhlemann
发明人： Steffen Weiss , Ronaldus Frederik Johannes Holthuizen , Sascha Krueger , Peter Koken , Daniel Wirtz , Thomas Erik Amthor , Falk Uhlemann
IPC分类号： A61B5/055 , G01R33/28 , A61B5/06 , A61B5/00 , G01R33/34
CPC分类号： A61B5/055 , A61B5/064 , A61B5/6832 , A61B5/72 , G01R33/287 , G01R33/34084
摘要： A medical apparatus (1100) comprising a magnetic resonance imaging system and an interventional device (300) comprising a shaft (302, 1014, 1120). The medical apparatus further comprises a toroidal magnetic resonance fiducial marker (306, 600, 800, 900, 1000, 1122) attached to the shaft. The shaft passes through a center point (610, 810, 908, 1006) of the fiducial marker. The medical apparatus further comprises machine executable instructions (1150, 1152, 1154, 1156, 1158) for execution by a processor. The instructions cause the processor to acquire (100, 200) magnetic resonance data, to reconstruct (102, 202) a magnetic resonance image (1142), and to receive (104, 204) the selection of a target volume (1118, 1144, 1168). The instructions further cause the processor to repeatedly: acquire (106, 206) magnetic resonance location data (1146) from the fiducial marker and render (108, 212) a view (1148, 1162) indicating the position of the shaft relative to the target zone.

5. 发明授权

US09575146B2 Method of characterizing 有权
标题翻译：表征方法
公开(公告)号：US09575146B2
公开(公告)日：2017-02-21
申请号：US13882293
申请日：2011-10-26
申请人： Johan Van Den Brink , Ingmar Graesslin , Sascha Krueger , Steffen Weiss , Peter Vernickel
发明人： Johan Van Den Brink , Ingmar Graesslin , Sascha Krueger , Steffen Weiss , Peter Vernickel
IPC分类号： G01R33/36 , G01R33/24 , G01R33/44 , G01R33/561 , G01R33/58
CPC分类号： G01R33/36 , G01R33/246 , G01R33/44 , G01R33/5612 , G01R33/583
摘要： The invention relates to a method of characterizing the RF transmit chain of a magnetic resonance imaging scanner (1) using a local transmit/receive coil system (204; 210), comprising a first local NMR probe and a first local magnetic resonance coil, the first NMR probe being spatially located in immediate neighborhood to the first coil, a local receive coil system (206; 208), comprising a second local NMR probe and a second local magnetic resonance coil, the second NMR probe being spatially located in immediate neighborhood to the second coil, wherein the transmit chain comprises an external MR coil (9; 11; 12; 13), the method comprising: determining with the first magnetic resonance coil, a first MR signal phase evolution of the local RF transmit field generated by MR excitation of the first probe using the first magnetic resonance coil by measuring the RF response of the first probe upon said excitation, determining with the second magnetic resonance coil a second MR signal phase evolution of the local RF transmit field generated by MR excitation of the second probe using the external MR coil (9; 11; 12; 13) by measuring the RF response of the second probe upon said excitation, calculating a phase offset between the first and second MR signal phase evolution.
摘要翻译：本发明涉及一种使用本地发射/接收线圈系统（204; 210）来表征磁共振成像扫描仪（1）的RF发射链的方法，该系统包括第一局部NMR探针和第一局部磁共振线圈，空间上位于第一线圈周围的第一NMR探针，包括第二局部NMR探针和第二局部磁共振线圈的局部接收线圈系统（206; 208），所述第二NMR探针在空间上位于紧邻附近所述第二线圈，其中所述发射链包括外部MR线圈（9; 11; 12; 13），所述方法包括：利用所述第一磁共振线圈确定由MR产生的所述本地RF发射场的第一MR信号相位演变通过在所述激发时测量第一探针的RF响应，使用第一磁共振线圈激发第一探针，用第二磁共振线圈确定第二MR信号相位ev 使用外部MR线圈（9; 9）对第二探针的MR激发产生的局部RF发射场的清零。 11; 12; 13）通过在所述激励时测量第二探针的RF响应，计算第一和第二MR信号相位演变之间的相位偏移。

6. 发明授权

US09429637B2 Interventional MR imaging with motion compensation 有权
标题翻译：介入MR成像与运动补偿
公开(公告)号：US09429637B2
公开(公告)日：2016-08-30
申请号：US13266261
申请日：2010-04-14
申请人： Sascha S. Krueger , Steffen Weiss , Bernd David , Oliver Lips , Robert Manzke
发明人： Sascha S. Krueger , Steffen Weiss , Bernd David , Oliver Lips , Robert Manzke
IPC分类号： A61B5/055 , G01R33/567 , A61B5/06 , A61B5/00 , G01R33/28 , G01R33/48 , G01R33/565
CPC分类号： G01R33/5673 , A61B5/055 , A61B5/064 , A61B5/7207 , A61B2034/2051 , G01R33/287 , G01R33/4824 , G01R33/56509
摘要： A method of magnetic resolution (MR) imaging of a moving portion of a body of a patient placed in an examination volume of a MR device. For the purpose of enabling improved interventional MR imaging from acquiring a MR signal data with motion compensation, the invention proposes that the method includes repeated acts of collecting tracking data from an interventional instrument introduced into the portion of the body, subjecting the portion of the body to an imaging sequence for acquiring one or more MR signals therefrom, wherein parameters of the imaging sequence are adjusted on the basis of the tracking data, and reconstructing one or more MR images from the MR signal data set.
摘要翻译：一种放置在MR装置的检查体积中的患者身体的移动部分的磁分辨（MR）成像方法。为了能够通过运动补偿获取MR信号数据来实现改进的介入MR成像，本发明提出了该方法包括从引入到身体部分的介入仪器收集跟踪数据的重复动作，使身体部分涉及从其获取一个或多个MR信号的成像序列，其中基于跟踪数据调整成像序列的参数，以及从MR信号数据集重建一个或多个MR图像。

7. 发明授权

US09348005B2 Interventional or non-interventional instrument for use in an MRI apparatus 有权
标题翻译：用于MRI装置的介入或非介入性仪器
公开(公告)号：US09348005B2
公开(公告)日：2016-05-24
申请号：US14240602
申请日：2012-08-29
申请人： Jouke Smink , Steffen Weiss
发明人： Jouke Smink , Steffen Weiss
IPC分类号： A61B5/05 , G01R33/28 , G01R33/36 , A61B5/01 , A61B5/042 , A61B5/00 , A61B10/02 , A61M25/01 , G01R33/54 , A61B5/055
CPC分类号： G01R33/287 , A61B5/01 , A61B5/042 , A61B5/055 , A61B5/6852 , A61B10/0233 , A61M25/0127 , G01R33/288 , G01R33/3685 , G01R33/54
摘要： An interventional or a non-interventional instrument like a catheter, a surgical device, a biopsy needle, a pointer, a stent or another invasive or non-invasive device, like a position marker, or a surface or local coil like a head coil is disclosed, wherein these instruments are provided with an MR-safe RF transmission line or cable (2, 3) for connecting the instrument with related RF transmit/MR receive units or other signal processing units for operating the instrument during an MR imaging or MR examination of an examination object. Basically, MR safety is obtained or increased by means of a plurality of fuses (6) which are serially connected into the transmission line or cable (2, 3).
摘要翻译：诸如导管，手术装置，活检针，指针，支架或另一侵入性或非侵入性装置（例如位置标记）或诸如头部线圈的表面或局部线圈的介入或非介入手段是公开了这些仪器，其中这些仪器设置有用于在MR成像或MR检查期间将仪器与相关的RF发射/ MR接收单元或其他信号处理单元连接以用于操作仪器的MR安全RF传输线或电缆（2,3）的考试对象。基本上，通过串联连接到传输线或电缆（2,3）中的多个保险丝（6）获得或增加了MR安全性。

8. 发明授权

US08847072B2 Transmission cable for use in radio-frequency magnetic or electrical fields 有权
标题翻译：用于射频磁场或电场的传输电缆
公开(公告)号：US08847072B2
公开(公告)日：2014-09-30
申请号：US12665947
申请日：2008-06-27
申请人： Sascha Krueger , Bernd David , Oliver Lips , Steffen Weiss , Daniel Wirtz
发明人： Sascha Krueger , Bernd David , Oliver Lips , Steffen Weiss , Daniel Wirtz
IPC分类号： H02G3/00 , H01R4/00 , H02G3/06 , H02G15/08 , H01B7/00 , H01B11/02 , H01P1/10 , H01H1/20 , H01H1/36 , G01R33/28 , G01R33/36 , A61B19/00 , A61B18/00 , A61N1/08 , A61B18/14
CPC分类号： G01R33/36 , A61B18/14 , A61B2018/00178 , A61B2090/374 , A61N1/086 , G01R33/287 , G01R33/288 , G01R33/3664
摘要： A transmission cable including a transmission line, at least two electrically conductive line segments separated by a non-conductive gap, a bridging unit including at least one electrically conductive bridge segment capable of bridging the non-conductive gap, and a switching unit arranged to move the bridging unit and/or the transmission line to electrically connect the two line segments by closing the non-conductive gap using the bridge segment or to electrically disconnect the two line segments by opening the non-conductive gap.
摘要翻译：一种传输电缆，包括传输线，由非导电间隙分开的至少两个导电线段，包括能够桥接非导电间隙的至少一个导电桥接段的桥接单元和布置成移动桥接单元和/或传输线，以通过使用桥接段闭合非导电间隙来电连接两个线段，或通过打开非导电间隙来电连接两个线段。

9. 发明申请

US20140121648A1 COMPOSITE FIBER GUIDEWIRES 审中-公开
标题翻译：复合纤维指南
公开(公告)号：US20140121648A1
公开(公告)日：2014-05-01
申请号：US14125737
申请日：2012-06-11
申请人： Steffen Weiss
发明人： Steffen Weiss
IPC分类号： A61M25/09 , B29C70/52
CPC分类号： A61M25/09 , A61B5/01 , A61B5/02154 , A61B5/055 , A61B5/11 , A61B5/6851 , A61B2562/12 , A61M2025/09108 , A61M2025/09133 , A61M2025/09175 , B29C70/52
摘要： A guide wire (400, 500, 600, 700, 800, 900, 1000, 1200, 1300) is adapted for use in magnetic resonance imaging systems. The guide wire has a shaft region (402) and a distal tip region (404). The shaft region comprises a composite shaft (406) comprising reinforcing fibers aligned with a length extension (403) of the shaft region. The fibers extend at least partially into the distal tip region. The fibers form a taper (410) within the distal tip region. The distal tip region comprises a sensor (504, 604, 702, 704, 804, 904, 1006, 1008). The shaft comprises a cable (502, 602, 702, 704, 802, 902, 1002, 1004). The cable is connected to the sensor.
摘要翻译：引导线（400,500,600,700,800,900,1000,1200,1300）适用于磁共振成像系统。引导线具有轴区域（402）和远端尖端区域（404）。轴区域包括复合轴（406），其包括与轴区域的长度延伸部（403）对准的增强纤维。纤维至少部分延伸到远侧末端区域。纤维在远端尖端区域内形成锥形（410）。远端尖端区域包括传感器（504,604,702,704,804,904,1006,1008）。轴包括电缆（502,602,702,704,802,902,1002,1004）。电缆连接到传感器。

10. 发明申请

US20140018664A1 MAGNETIC RESONANCE GUIDANCE OF A SHAFT TO A TARGET ZONE 有权
标题翻译：对目标区域的磁共振指导
公开(公告)号：US20140018664A1
公开(公告)日：2014-01-16
申请号：US14007990
申请日：2012-04-04
申请人： Steffen Weiss , Ronaldus Frederik Johannes Holthuizen , Sascha Krueger , Peter Koken , Daniel Wirtz , Thomas Erik Amthor , Alk Uhlemann
发明人： Steffen Weiss , Ronaldus Frederik Johannes Holthuizen , Sascha Krueger , Peter Koken , Daniel Wirtz , Thomas Erik Amthor , Alk Uhlemann
IPC分类号： A61B5/055 , A61B5/00 , A61B5/06
CPC分类号： A61B5/055 , A61B5/064 , A61B5/6832 , A61B5/72 , G01R33/287 , G01R33/34084
摘要： A medical apparatus (1100) comprising a magnetic resonance imaging system and an interventional device (300) comprising a shaft (302, 1014, 1120). The medical apparatus further comprises a toroidal magnetic resonance fiducial marker (306, 600, 800, 900, 1000, 1122) attached to the shaft. The shaft passes through a center point (610, 810, 908, 1006) of the fiducial marker. The medical apparatus further comprises machine executable instructions (1150, 1152, 1154, 1156, 1158) for execution by a processor. The instructions cause the processor to acquire (100, 200) magnetic resonance data, to reconstruct (102, 202) a magnetic resonance image (1142), and to receive (104, 204) the selection of a target volume (1118, 1144, 1168). The instructions further cause the processor to repeatedly: acquire (106, 206) magnetic resonance location data (1146) from the fiducial marker and render (108, 212) a view (1148, 1162) indicating the position of the shaft relative to the target zone.
摘要翻译：一种包括磁共振成像系统和包括轴（302,1014,1120）的介入装置（300）的医疗装置（1100）。医疗装置还包括连接到轴的环形磁共振基准标记（306,600,800,900,1000,1122）。轴通过基准标记的中心点（610,810,908,1006）。医疗设备还包括用于由处理器执行的机器可执行指令（1150,1152,1154,1156,1158）。所述指令使得所述处理器获取（100,200）磁共振数据，以重建（102,202）磁共振图像（1142），并且接收（104,204）所述目标体积（1118,1144， 1168）。所述指令还使所述处理器重复地：从所述基准标记获取（106,206）磁共振位置数据（1146），并且渲染（108,212）指示所述轴相对于所述目标的位置的视图（1148,1162）区。

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