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1. 发明申请

US20100174343A1 APPARATUS AND METHODS FOR FACILITATING WOUND HEALING AND TREATING SKIN 审中-公开
标题翻译：促进创伤和治疗皮肤的装置和方法
公开(公告)号：US20100174343A1
公开(公告)日：2010-07-08
申请号：US12537670
申请日：2009-08-07
申请人： Rafael Victor Andino , Christopher J. Brooks , Michael J. Keating , Courtney F. Morgan , Donald Van Royen
发明人： Rafael Victor Andino , Christopher J. Brooks , Michael J. Keating , Courtney F. Morgan , Donald Van Royen
IPC分类号： A61N1/02
CPC分类号： A61N1/205 , A61N1/326
摘要： Electrode systems and methods are provided for applying electrical stimulation to a wound or skin. The electrode systems may include a feedback sensor configured to detect at least one wound healing factor or other treatment factors and may adjust the electrical stimulation based on feedback sensor measurements. The electrode systems may include multiple center electrodes for attachment to the wound. Multiple therapies may be stored on the electrode systems and a selected one of the stored therapies may be applied. A timer may be included to indicate the length of time a therapy has been applied. The electrode system may include a control module configured as a flexible circuit which conforms to the shape of the wound or the skin to which it is applied. In addition, a medical kit may be supplied for use in applying therapies, including multiple control modules and multiple electrodes.
摘要翻译：提供电极系统和方法以对伤口或皮肤施加电刺激。电极系统可以包括被配置为检测至少一个伤口愈合因子或其他治疗因素的反馈传感器，并且可以基于反馈传感器测量来调节电刺激。电极系统可以包括用于附接到伤口的多个中心电极。可以将多种疗法存储在电极系统上，并且可以应用所选存储的疗法。可以包括定时器以指示已经应用治疗的时间长度。电极系统可以包括配置为柔性电路的控制模块，其符合伤口或其所施加的皮肤的形状。此外，可以提供医疗套件用于应用治疗，包括多个控制模块和多个电极。

2. 发明申请

US20080027509A1 Apparatus and methods for facilitating wound healing and treating skin 审中-公开
标题翻译：用于促进伤口愈合和治疗皮肤的装置和方法
公开(公告)号：US20080027509A1
公开(公告)日：2008-01-31
申请号：US11494819
申请日：2006-07-28
申请人： Rafael Victor Andino , Christopher J. Brooks , Michael J. Keating , Courtney F. Morgan , Donald Van Royen
发明人： Rafael Victor Andino , Christopher J. Brooks , Michael J. Keating , Courtney F. Morgan , Donald Van Royen
IPC分类号： A61N1/18
CPC分类号： A61N1/205 , A61N1/326
摘要： Electrode systems and methods are provided for applying electrical stimulation to a wound or skin. The electrode systems may include a feedback sensor configured to detect at least one wound healing factor or other treatment factors and may adjust the electrical stimulation based on feedback sensor measurements. The electrode systems may include multiple center electrodes for attachment to the wound. Multiple therapies may be stored on the electrode systems and a selected one of the stored therapies may be applied. A timer may be included to indicate the length of time a therapy has been applied. The electrode system may include a control module configured as a flexible circuit which conforms to the shape of the wound or the skin to which it is applied. In addition, a medical kit may be supplied for use in applying therapies, including multiple control modules and multiple electrodes.
摘要翻译：提供电极系统和方法以对伤口或皮肤施加电刺激。电极系统可以包括被配置为检测至少一个伤口愈合因子或其他治疗因素的反馈传感器，并且可以基于反馈传感器测量来调节电刺激。电极系统可以包括用于附接到伤口的多个中心电极。可以将多种疗法存储在电极系统上，并且可以应用所选存储的疗法。可以包括定时器以指示已经应用治疗的时间长度。电极系统可以包括配置为柔性电路的控制模块，其符合伤口或其所施加的皮肤的形状。此外，可以提供医疗套件用于应用治疗，包括多个控制模块和多个电极。

3. 发明授权

US07122050B2 Delivery mechanism for implantable stent 有权
公开(公告)号：US07122050B2
公开(公告)日：2006-10-17
申请号：US10357985
申请日：2003-02-04
申请人： Scott L. Randall , Christopher J. Brooks , Brendan J. McCrea , Donald Van Royen
发明人： Scott L. Randall , Christopher J. Brooks , Brendan J. McCrea , Donald Van Royen
IPC分类号： A61F2/06 , A61F11/00
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9517
摘要： A delivery mechanism for an implantable stent which provides a high mechanical advantage to the surgeon and convenient operation so as to facilitate smooth withdrawal of an outer catheter sheath following placement of the stent in the desired location within the patient's vessel. Preferred embodiments include a moving rail actuated by a V-shaped lever, a hydraulic actuator, a rack and pinion drive, and a power screw system. The delivery mechanism has a movable member that is attached to the outer catheter sheath so that actuating the mechanism results in an incremental movement of the moveable member, which in turn results in an incremental movement of the outer catheter sheath. Once the outer catheter sheath is retracted from the stent, the stent is deployed into the patient's vessel and the remaining parts of the mechanism, including an inner tube, an atraumatic tip, and a stabilizing element, are easily removed.

4. 发明授权

US06514261B1 Delivery mechanism for implantable stent 有权
标题翻译：植入式支架的输送机制
公开(公告)号：US06514261B1
公开(公告)日：2003-02-04
申请号：US09409210
申请日：1999-09-30
申请人： Scott L. Randall , Brendan J. McCrea , Christopher J. Brooks , Donald Van Royen
发明人： Scott L. Randall , Brendan J. McCrea , Christopher J. Brooks , Donald Van Royen
IPC分类号： A61B1700
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9517
摘要： A delivery mechanism for an implantable stent which provides a high mechanical advantage to the surgeon and convenient operation so as to facilitate smooth withdrawal of an outer catheter sheath following placement of the stent in the desired location within the patient's vessel. Preferred embodiments include a moving rail actuated by a V-shaped lever, a hydraulic actuator, a rack and pinion drive, and a power screw system. The delivery mechanism has a movable member that is attached to the outer catheter sheath so that actuating the mechanism results in an incremental movement of the moveable member, which in turn results in an incremental movement of the outer catheter sheath. Once the outer catheter sheath is retracted from the stent, the stent is deployed into the patient's vessel and the remaining parts of the mechanism, including an inner tube, an atraumatic tip, and a stabilizing element, are easily removed.
摘要翻译：用于可植入支架的输送机构，其为外科医生提供高机械优点并且方便的操作，以便在将支架放置在患者血管内的期望位置之后促进外导管套管的顺利抽出。优选实施例包括由V形杠杆，液压致动器，齿条和小齿轮驱动器以及动力螺杆系统致动的移动轨道。递送机构具有附接到外导管护套的可移动构件，使得致动机构导致可移动构件的增量运动，这又导致外导管护套的增量运动。一旦外导管护套从支架缩回，支架将展开到患者的血管中，机构的其余部分（包括内管，无创尖端和稳定元件）容易被移除。

5. 发明授权

US07691120B2 Access systems and methods for minimally invasive surgery 有权
标题翻译：用于微创手术的接入系统和方法
公开(公告)号：US07691120B2
公开(公告)日：2010-04-06
申请号：US10926840
申请日：2004-08-26
申请人： Alan E. Shluzas , Gene P. DiPoto , Gary L. Lowery , Karl Dallas Kirk, III , Walter Stoeckmann , Donald Van Royen
发明人： Alan E. Shluzas , Gene P. DiPoto , Gary L. Lowery , Karl Dallas Kirk, III , Walter Stoeckmann , Donald Van Royen
IPC分类号： A61M29/00
CPC分类号： A61B1/313 , A61B1/00149 , A61B1/00154 , A61B1/31 , A61B1/3135 , A61B17/00 , A61B17/02 , A61B17/0218 , A61B17/1757 , A61B17/32002 , A61B17/3403 , A61B17/3423 , A61B17/3439 , A61B17/3462 , A61B17/7001 , A61B17/7007 , A61B17/701 , A61B17/7032 , A61B17/7037 , A61B17/7038 , A61B17/7041 , A61B17/7044 , A61B17/7058 , A61B17/7082 , A61B17/7083 , A61B17/7085 , A61B17/8875 , A61B34/70 , A61B90/11 , A61B90/30 , A61B90/361 , A61B90/50 , A61B2017/00261 , A61B2017/00557 , A61B2090/062 , A61B2090/08021 , A61B2090/306 , A61B2217/005 , A61B2217/007
摘要： A device for provides access to a surgical location within a patient. The device has an elongate body that has a proximal portion, a distal portion, a first slot segment, and a second slot segment that is angled relative to said first slot segment. The elongate body defines a passage for accessing the surgical location with surgical instruments. The elongate body has a contracted configuration for insertion into the patient and an expanded configuration for providing access to the surgical location. The cross-sectional area of the passage at a first location of the elongate body is greater than the cross-sectional area of said passage at a second location of the elongate body. A movable tab is configured to extend into the second slot segment when the elongate body is in the expanded configuration to retain the elongate body in the expanded configuration.
摘要翻译：用于提供对患者内的手术位置的访问的装置。该装置具有细长主体，其具有近端部分，远侧部分，第一狭槽部分和相对于所述第一狭槽部分成角度的第二狭槽部分。细长主体限定了一个通过手术器械进入手术位置的通道。细长体具有用于插入到患者体内的收缩构造和用于提供对手术位置的通路的扩张构型。在细长主体的第一位置处的通道的横截面积大于在细长主体的第二位置处的所述通道的横截面面积。可移动突出部构造成当细长主体处于膨胀构型中时延伸到第二槽段中，以将细长主体保持在膨胀构型中。

6. 发明申请

US20090048504A1 Medical electrode systems and methods 审中-公开
公开(公告)号：US20090048504A1
公开(公告)日：2009-02-19
申请号：US11893815
申请日：2007-08-17
申请人： Rafael V. Andino , Christopher Brooks , Michael Keating , Courtney Morgan , Donald Van Royen
发明人： Rafael V. Andino , Christopher Brooks , Michael Keating , Courtney Morgan , Donald Van Royen
IPC分类号： A61B5/04
CPC分类号： A61N1/0468 , A61B5/445 , A61B2562/043 , A61N1/0472 , A61N1/0476 , A61N1/0492 , A61N1/0496 , A61N1/205
摘要： Systems, methods, and devices are provided for creating and applying electrodes and electrode systems to a wound or skin. An electrode may be applied as a single electrode strip using a dispenser. An electrode may also be cut to size from a single sheet of electrode. Additionally, an electrode may be formed from a plurality of electrode segments which may be connected together. Electrodes can also be incorporated as part of drainage tubes. A medical electrode kit may be provided that includes multiple electrode segments and connectors, multiple electrodes, and multiple control modules. In addition, electrodes or electrode systems may be provided with a color scoring chart. An electrode system may be configured to interface with a selected body part. Electrode systems may include sensors and electrodes configured for application to areas outside of a wound or the skin intended to be treated.

7. 发明申请

US20090048635A1 Medical electrode systems and methods 审中-公开
标题翻译：医用电极系统及方法
公开(公告)号：US20090048635A1
公开(公告)日：2009-02-19
申请号：US11893814
申请日：2007-08-17
申请人： Rafael V. Andino , Christopher Brooks , Michael Keating , Courtney Morgan , Donald Van Royen
发明人： Rafael V. Andino , Christopher Brooks , Michael Keating , Courtney Morgan , Donald Van Royen
IPC分类号： A61N1/00
CPC分类号： A61N1/0468 , A61F15/002 , A61N1/0472 , A61N1/0476 , A61N1/0492 , A61N1/0496 , A61N1/205
摘要： Systems, methods, and devices are provided for creating and applying electrodes and electrode systems to a wound or skin. An electrode may be applied as a single electrode strip using a dispenser. An electrode may also be cut to size from a single sheet of electrode. Additionally, an electrode may be formed from a plurality of electrode segments which may be connected together. Electrodes can also be incorporated as part of drainage tubes. A medical electrode kit may be provided that includes multiple electrode segments and connectors, multiple electrodes, and multiple control modules. In addition, electrodes or electrode systems may be provided with a color scoring chart. An electrode system may be configured to interface with a selected body part. Electrode systems may include sensors and electrodes configured for application to areas outside of a wound or the skin intended to be treated.
摘要翻译：提供了系统，方法和装置，用于创建和应用电极和电极系统到伤口或皮肤。电极可以使用分配器作为单个电极条施加。电极也可以从单片电极切割成尺寸。另外，电极可以由可以连接在一起的多个电极段形成。电极也可作为排水管的一部分。可以提供包括多个电极段和连接器，多个电极和多个控制模块的医疗电极套件。此外，电极或电极系统可以设置有颜色评分图。电极系统可以被配置为与所选择的身体部分相接。电极系统可以包括被配置用于施加到伤口外面的区域或要被治疗的皮肤的传感器和电极。

8. 发明授权

US06631294B2 Apparatus and methods for facilitating wound healing 有权
标题翻译：用于促进伤口愈合的装置和方法
公开(公告)号：US06631294B2
公开(公告)日：2003-10-07
申请号：US09872956
申请日：2001-06-01
申请人： Rafael Andino , Christopher Brooks , Donald Van Royen
发明人： Rafael Andino , Christopher Brooks , Donald Van Royen
IPC分类号： A61N104
CPC分类号： A61N1/0468 , A61N1/0476 , A61N1/0492 , A61N1/0496 , A61N1/205
摘要： An electrode system is provided that generates a current flow that envelops and permeates an entire wound site. The electrode system includes two electrodes that are shaped and oriented to cause the current to flow from one electrode through the wound to the other electrode. A first electrode is applied to the wound site and the second electrode encircles the first electrode and is applied to the skin surrounding the wound cite. The two electrodes may be mounted to an oxygen-permeable layer that provides support for the electrodes and allows the wound site to breathe. An electrically insulative element may be disposed between the two electrodes. A power supply, which may be local to or remote from the electrode system, is provided for applying a voltage potential across the electrodes. In another suitable embodiment, the two electrodes are comprised of oppositely charged polymers.
摘要翻译：提供电极系统，其产生包围并渗透整个伤口部位的电流。电极系统包括两个电极，其形状和取向以使电流从一个电极通过伤口流动到另一个电极。将第一电极施加到伤口部位，并且第二电极环绕第一电极并施加到围绕伤口的皮肤上。两个电极可以被安装到氧气渗透层，其提供对电极的支撑并允许伤口部位呼吸。电绝缘元件可以设置在两个电极之间。电源可以是局部的或远离电极系统，用于在电极两端施加电压电位。在另一个合适的实施方案中，两个电极由带相反电荷的聚合物构成。

9. 发明申请

US20070032860A1 Delivery mechanism for implantable stent 有权
标题翻译：植入式支架的输送机制
公开(公告)号：US20070032860A1
公开(公告)日：2007-02-08
申请号：US11581645
申请日：2006-10-16
申请人： Christopher Brooks , Brendan McCrea , Scott Randall , Donald Van Royen
发明人： Christopher Brooks , Brendan McCrea , Scott Randall , Donald Van Royen
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9517
摘要： A delivery system including an inner catheter with a reinforcing element and an outer catheter having a proximal end attached to a movable member. An abutment element may be attached to a distal end of the reinforcing element, configured to engage an implantable device disposed between the inner catheter and the outer catheter.
摘要翻译：一种输送系统，包括具有加强元件的内导管和具有附接到可移动元件的近端的外导管。邻接元件可以附接到加强元件的远端，构造成接合设置在内导管和外导管之间的可植入装置。

10. 发明授权

US06907294B2 Apparatus and methods for facilitating wound healing 有权
标题翻译：用于促进伤口愈合的装置和方法
公开(公告)号：US06907294B2
公开(公告)日：2005-06-14
申请号：US10620727
申请日：2003-07-15
申请人： Rafael Andino , Christopher Brooks , Donald Van Royen
发明人： Rafael Andino , Christopher Brooks , Donald Van Royen
IPC分类号： A61N1/04 , A61N1/20
CPC分类号： A61N1/0468 , A61N1/0476 , A61N1/0492 , A61N1/0496 , A61N1/205
摘要： An electrode system is provided that generates a current flow that envelops and permeates an entire wound site. The electrode system includes two electrodes that are shaped and oriented to cause the current to flow from one electrode through the wound to the other electrode. A first electrode is applied to the wound site and the second electrode encircles the first electrode and is applied to the skin surrounding the wound cite. The two electrodes may be mounted to an oxygen-permeable layer that provides support for the electrodes and allows the wound site to breathe. An electrically insulative element may be disposed between the two electrodes. A power supply, which may be local to or remote from the electrode system, is provided for applying a voltage potential across the electrodes. In another suitable embodiment, the two electrodes are comprised of oppositely charged polymers.
摘要翻译：提供电极系统，其产生包围并渗透整个伤口部位的电流。电极系统包括两个电极，其形状和取向以使电流从一个电极通过伤口流动到另一个电极。将第一电极施加到伤口部位，并且第二电极环绕第一电极并施加到围绕伤口的皮肤上。两个电极可以被安装到氧气渗透层，其提供对电极的支撑并允许伤口部位呼吸。电绝缘元件可以设置在两个电极之间。电源可以是局部的或远离电极系统，用于在电极两端施加电压电位。在另一个合适的实施方案中，两个电极由带相反电荷的聚合物构成。

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