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1. 发明申请

US20070191921A1 SENSORS HAVING PROTECTIVE ELUTING COATING AND METHOD THEREFOR 有权
标题翻译：具有保护性涂层涂层的传感器及其方法
公开(公告)号：US20070191921A1
公开(公告)日：2007-08-16
申请号：US11738251
申请日：2007-04-20
申请人： Qingsheng Zhu , Ronald Heil , Mudit Jain
发明人： Qingsheng Zhu , Ronald Heil , Mudit Jain
IPC分类号： A61N1/05
CPC分类号： A61B5/14546 , A61B5/14532 , A61N1/0568
摘要： An apparatus includes an implantable device, such as a chronically implantable device that has a device body. One or more chemical sensors are coupled with the device body. A drug eluting substance is disposed at a location including at least one of on, directly adjacent, or near the one or more chemical sensors, where the drug eluting substance prevents fibrotic growth on the one or more chemical sensors.
摘要翻译：一种装置包括可植入装置，例如具有装置主体的长期可植入装置。一个或多个化学传感器与装置本体结合。药物洗脱物质被布置在包括一个或多个化学传感器中的至少一个，直接相邻或接近的位置，其中药物洗脱物质防止在一个或多个化学传感器上的纤维化生长。

2. 发明申请

US20050070768A1 Sensors having protective eluting coating and method therefor 有权
标题翻译：具有保护性洗脱涂层的传感器及其方法
公开(公告)号：US20050070768A1
公开(公告)日：2005-03-31
申请号：US10677144
申请日：2003-09-30
申请人： Qingsheng Zhu , Ronald Heil , Mudit Jain
发明人： Qingsheng Zhu , Ronald Heil , Mudit Jain
IPC分类号： A61B5/00 , A61N1/05
CPC分类号： A61B5/14546 , A61B5/14532 , A61N1/0568
摘要： An apparatus includes an implantable device, such as a chronically implantable device that has a device body. One or more chemical sensors are coupled with the device body. A drug eluting substance is disposed at a location including at least one of on, directly adjacent, or near the one or more chemical sensors, where the drug eluting substance prevents fibrotic growth on the one or more chemical sensors.
摘要翻译：一种装置包括可植入装置，例如具有装置主体的长期可植入装置。一个或多个化学传感器与装置本体结合。药物洗脱物质被布置在包括一个或多个化学传感器中的至少一个，直接相邻或接近的位置，其中药物洗脱物质防止在一个或多个化学传感器上的纤维化生长。

3. 发明授权

US07225024B2 Sensors having protective eluting coating and method therefor 有权
标题翻译：具有保护性洗脱涂层的传感器及其方法
公开(公告)号：US07225024B2
公开(公告)日：2007-05-29
申请号：US10677144
申请日：2003-09-30
申请人： Qingsheng Zhu , Ronald W. Heil, Jr. , Mudit Jain
发明人： Qingsheng Zhu , Ronald W. Heil, Jr. , Mudit Jain
IPC分类号： A61N1/365 , A61B5/00
CPC分类号： A61B5/14546 , A61B5/14532 , A61N1/0568
摘要： A cardiac management implantable device that has an intravascular device body, and one or more chemical sensors coupled with the intravascular device body. A drug eluting substance is disposed at a location including at least one of on, directly adjacent, or near the one or more chemical sensors, where the drug eluting substance prevents fibrotic growth on the one or more chemical sensors.
摘要翻译：一种具有血管内装置体的心脏管理可植入装置，以及与血管内装置本体结合的一个或多个化学传感器。药物洗脱物质被布置在包括一个或多个化学传感器中的至少一个，直接相邻或接近的位置，其中药物洗脱物质防止在一个或多个化学传感器上的纤维化生长。

4. 发明授权

US08131364B2 Sensors having protective eluting coating and method therefor 有权
标题翻译：具有保护性洗脱涂层的传感器及其方法
公开(公告)号：US08131364B2
公开(公告)日：2012-03-06
申请号：US12984161
申请日：2011-01-04
申请人： Qingsheng Zhu , Ronald W. Heil, Jr. , Mudit Jain
发明人： Qingsheng Zhu , Ronald W. Heil, Jr. , Mudit Jain
IPC分类号： A61N1/00
CPC分类号： A61B5/14546 , A61B5/14532 , A61N1/0568
摘要： An apparatus includes an implantable device, such as a chronically implantable device that has a device body. One or more chemical sensors are coupled with the device body. A drug eluting substance is disposed at a location including at least one of on, directly adjacent, or near the one or more chemical sensors, where the drug eluting substance prevents fibrotic growth on the one or more chemical sensors.
摘要翻译：一种装置包括可植入装置，例如具有装置主体的长期可植入装置。一个或多个化学传感器与装置本体结合。药物洗脱物质被布置在包括一个或多个化学传感器中的至少一个，直接相邻或接近的位置，其中药物洗脱物质防止在一个或多个化学传感器上的纤维化生长。

5. 发明授权

US07890171B2 Sensors having protective eluting coating and method therefor 有权
标题翻译：具有保护性洗脱涂层的传感器及其方法
公开(公告)号：US07890171B2
公开(公告)日：2011-02-15
申请号：US11738251
申请日：2007-04-20
申请人： Qingsheng Zhu , Ronald W. Heil, Jr. , Mudit Jain
发明人： Qingsheng Zhu , Ronald W. Heil, Jr. , Mudit Jain
IPC分类号： A61N1/00
CPC分类号： A61B5/14546 , A61B5/14532 , A61N1/0568
摘要： An apparatus includes an implantable device, such as a chronically implantable device that has a device body. One or more chemical sensors are coupled with the device body. A drug eluting substance is disposed at a location including at least one of on, directly adjacent, or near the one or more chemical sensors, where the drug eluting substance prevents fibrotic growth on the one or more chemical sensors.
摘要翻译：一种装置包括可植入装置，例如具有装置主体的长期可植入装置。一个或多个化学传感器与装置本体结合。药物洗脱物质被布置在包括一个或多个化学传感器中的至少一个，直接相邻或接近的位置，其中药物洗脱物质防止在一个或多个化学传感器上的纤维化生长。

6. 发明申请

US20110098547A1 SENSORS HAVING PROTECTIVE ELUTING COATING AND METHOD THEREFOR 有权
标题翻译：具有保护性涂层涂层的传感器及其方法
公开(公告)号：US20110098547A1
公开(公告)日：2011-04-28
申请号：US12984161
申请日：2011-01-04
申请人： Qingsheng Zhu , Ronald W. Heil, JR. , Mudit Jain
发明人： Qingsheng Zhu , Ronald W. Heil, JR. , Mudit Jain
IPC分类号： A61B5/145
CPC分类号： A61B5/14546 , A61B5/14532 , A61N1/0568
摘要： An apparatus includes an implantable device, such as a chronically implantable device that has a device body. One or more chemical sensors are coupled with the device body. A drug eluting substance is disposed at a location including at least one of on, directly adjacent, or near the one or more chemical sensors, where the drug eluting substance prevents fibrotic growth on the one or more chemical sensors.
摘要翻译：一种装置包括可植入装置，例如具有装置主体的长期可植入装置。一个或多个化学传感器与装置本体结合。药物洗脱物质被布置在包括一个或多个化学传感器中的至少一个，直接相邻或接近的位置，其中药物洗脱物质防止在一个或多个化学传感器上的纤维化生长。

7. 发明授权

US06909919B2 Cardiac lead incorporating strain gauge for assessing cardiac contractility 失效
标题翻译：用于评估心脏收缩力的心脏导联
公开(公告)号：US06909919B2
公开(公告)日：2005-06-21
申请号：US10236310
申请日：2002-09-06
申请人： Mudit Jain , Qingsheng Zhu , Rodney W. Salo
发明人： Mudit Jain , Qingsheng Zhu , Rodney W. Salo
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： For chronic monitoring of the effects of pacing and/or drug therapy in treating CHF, a strain gauge element is disposed at the distal end of a cardiac lead and is effective to produce a signal relating to the amount of flexure being induced into the lead by the beating action of the heart.
摘要翻译：为了慢性监测起搏和/或药物治疗在治疗CHF中的作用，应变计元件设置在心脏引线的远端，并且有效地产生与通过引导引入的弯曲量相关的信号心跳的动作。

8. 发明授权

US08825155B2 Systems, devices and methods relating to endocardial pacing for resynchronization 有权
标题翻译：与心内膜起搏相关的系统，装置和方法用于再同步
公开(公告)号：US08825155B2
公开(公告)日：2014-09-02
申请号：US13223919
申请日：2011-09-01
申请人： Qingsheng Zhu , Daniel Felipe Ortega
发明人： Qingsheng Zhu , Daniel Felipe Ortega
IPC分类号： A61N1/362 , A61N1/36 , A61N1/368 , A61N1/05
CPC分类号： A61N1/3627 , A61N1/056 , A61N1/0565 , A61N1/36114 , A61N1/3625 , A61N1/368 , A61N1/3684
摘要： Disclosed are certain methods, apparatus, and processor-readable mediums that may be used to treat a conduction abnormality of the heart. In one example, the apparatus includes an implantable pacing profile generator configured to generate a specified pacing electrostimulation profile for delivery to a heart via electrodes located near a septal region of the right ventricle of the heart near the His bundle, the pacing profile including a first pulse for delivery via a first electrode; and a second pulse for delivery via a second electrode; and wherein the first and second pulses are at least partially concurrent in time and opposite in polarity to each other.
摘要翻译：公开了可用于治疗心脏传导异常的某些方法，装置和处理器可读介质。在一个示例中，该装置包括植入式起搏分布生成器，其被配置为产生指定的起搏电刺激曲线，用于经由靠近His束的位于心脏右心室附近的电极的电极递送至心脏，起搏曲线包括第一用于经由第一电极传送的脉冲; 以及用于经由第二电极传送的第二脉冲; 并且其中所述第一和第二脉冲在时间上至少部分同时并且彼此极性相反。

9. 发明授权

US08326423B2 Devices and methods for steering electrical stimulation in cardiac rhythm management 有权
标题翻译：用于在心律管理中转向电刺激的装置和方法
公开(公告)号：US08326423B2
公开(公告)日：2012-12-04
申请号：US12147317
申请日：2008-06-26
申请人： Qingsheng Zhu , Daniel Felipe Ortega
发明人： Qingsheng Zhu , Daniel Felipe Ortega
IPC分类号： A61N1/372
CPC分类号： A61N1/37 , A61N1/3627
摘要： Tools and methods are particularly suited for certain cardiac conditions involving use of a catheter for pacing of the right and left ventricles from a lead in the right ventricle, e.g., to facilitate mechanically and/or electrically synchronous contractions for resynchronization. Certain aspects involve pacing and/or mapping by delivering pulses to a cardiac site useful for improving heart function as measured, e.g., by QRS width, fractionation, late LV activation timing, mechanical synchronicity of free wall and septal wall, effective throughput/pressure, or a combination thereof. In one embodiment, a catheter arrangement includes a fixation mechanism to attach the catheter arrangement to heart tissue, individually-addressable electrodes for providing pacing signals to the heart tissue, and an elongated structure that supports the fixation mechanism and the electrodes. The elongated structure is used to direct an end thereof to the target region in the right ventricle, and deliver an electrical pacing signal to different portions within the target region of the heart when the fixation mechanism is operative to attach to heart tissue and also when the fixation mechanism is not attaching the catheter arrangement to heart tissue.
摘要翻译：工具和方法特别适合于某些心脏状况，包括使用导管将右心室和左心室从右心室中的引线起搏，例如为了促进用于再同步的机械和/或电同步收缩。某些方面涉及通过将脉搏递送到心脏位置，用于改善心脏功能，例如通过QRS宽度，分级，晚期LV激活时间，游离壁和间隔壁的机械同步性，有效吞吐量/压力，或其组合。在一个实施例中，导管装置包括用于将导管装置附接到心脏组织的固定机构，用于向心脏组织提供起搏信号的单独寻址电极，以及支撑固定机构和电极的细长结构。细长结构用于将其末端引导到右心室中的目标区域，并且当固定机构可操作地附接到心脏组织时，以及当心脏组织工作时，将电起搏信号递送到心脏的目标区域内的不同部分固定机构不将导管装置附接到心脏组织。

10. 发明申请

US20120209130A1 APPARATUS AND METHOD FOR OUTPUTTING HEART SOUNDS 有权
标题翻译：用于输出心脏声音的装置和方法
公开(公告)号：US20120209130A1
公开(公告)日：2012-08-16
申请号：US13456795
申请日：2012-04-26
申请人： Avram Scheiner , Qingsheng Zhu , Arthur L. Olive , Don Villalta
发明人： Avram Scheiner , Qingsheng Zhu , Arthur L. Olive , Don Villalta
IPC分类号： A61B5/0402 , A61B7/00
CPC分类号： A61B7/04 , A61B5/0002 , A61B5/0031 , A61B5/04012 , A61B5/04014 , A61B5/0402 , A61B5/042 , A61B5/044 , A61B5/0452 , A61B5/1118 , A61B5/742 , A61B7/023 , G06F19/00
摘要： An apparatus for outputting heart sounds includes an implantable system and an external system. The implantable system includes a sensor for generating sensed signals representing detected heart sounds, an interface circuit and a control circuit for receiving the sensed signals, generating data representing the heart sounds therefrom, and transmitting the data to the external system via the interface circuit. The external system includes an interface circuit for communicating with the implantable system, and a control circuit for receiving the data representing the heart sounds and for generating control signals that cause an output device to generate outputs representing the sounds. The implantable system may also include a sensor(s) for detecting cardiac electrical signals. In this case, outputs representing the cardiac electrical signals are also output.
摘要翻译：用于输出心音的装置包括可植入系统和外部系统。可植入系统包括用于产生表示检测到的心音的感测信号的传感器，接口电路和用于接收感测信号的控制电路，产生表示心音的数据，以及经由接口电路将数据发送到外部系统。外部系统包括用于与可植入系统进行通信的接口电路，以及用于接收表示心脏声音的数据的控制电路，以及用于产生使输出设备产生表示声音的输出的控制信号。可植入系统还可以包括用于检测心脏电信号的传感器。在这种情况下，还输出表示心电信号的输出。

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