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    • 8. 发明授权
    • Patient identification for the pacing therapy using LV-RV pressure loop
    • 使用LV-RV压力回路进行起搏治疗的患者鉴定
    • US06280389B1
    • 2001-08-28
    • US09439228
    • 1999-11-12
    • Jiang DingYinghong YuJulio Spinelli
    • Jiang DingYinghong YuJulio Spinelli
    • A61B5021
    • A61N1/365A61N1/3622A61N1/3627A61N1/37
    • A method and apparatus for determining whether a patient with congestive heart failure (CHF) will benefit from pacing therapy through the use of an implantable cardiac rhythm management device. A patient's right ventricular and left ventricular pressures are measured, and the patient's PP_Area is calculated for each normal heartbeat that occurs during the testing period. Depending upon the value of the patient's mean PP_Area, it can be determined whether the patient will or will not respond well acutely to pacing therapy. A mean PP_Area value of greater than or equal to a predetermined threshold, which is about 0.3, indicates that the patient is a responder to pacing therapy, while a value of less than the predetermined threshold of about 0.3 indicates that the patient is a non-responder.
    • 一种用于确定患有充血性心力衰竭(CHF)的患者是否将通过使用植入式心律管理装置从起搏治疗中受益的方法和装置。 测量患者的右心室和左心室压力,并计算在测试期间发生的每个正常心跳的患者的PP_Area。 根据患者平均PP_Area的价值,可以确定患者是否会或不会对起搏治疗产生很好的反应。 大于或等于预定阈值(约0.3)的平均PP_Area值表示患者是起搏治疗的应答​​者,而小于约0.3的预定阈值的值表示患者是非 - 响应者。
    • 9. 发明申请
    • METHOD AND APPARATUS FOR PREDICTING ACUTE RESPONSE TO CARDIAC RESYNCHRONIZATION THERAPY
    • 预防心脏康复治疗急性反应的方法和装置
    • US20080097542A1
    • 2008-04-24
    • US11962708
    • 2007-12-21
    • Yinghong YuJiang DingJulio SpinelliAngelo Auricchio
    • Yinghong YuJiang DingJulio SpinelliAngelo Auricchio
    • A61N1/365
    • A61N1/3627A61N1/3682
    • A method and apparatus for predicting acute response to cardiac resynchronization therapy is disclosed. The method can comprise measuring a first interval during an intrinsic systolic cycle and measuring a second interval during a stimulated systolic cycle. The acute response can be predicted by comparing the percent change in duration between the first interval and the second interval against a pre-determined threshold value. The first and second time intervals can be measured using, for example, a surface ECG or, alternatively, an intracardiac electrogram. In one embodiment, the first interval can be the duration of an intrinsic QRS complex measured during a non-stimulated systolic cycle. Similarly, the second interval can be the duration of a stimulated QRS complex measured during a stimulated systolic cycle.
    • 公开了用于预测心脏再同步治疗的急性反应的方法和装置。 该方法可以包括在本征收缩周期期间测量第一间隔并且在刺激的收缩期期间测量第二间隔。 可以通过将第一间隔和第二间隔之间的持续时间的百分比变化与预定阈值进行比较来预测急性反应。 第一和第二时间间隔可以使用例如表面ECG或者心内电描记图来测量。 在一个实施例中,第一间隔可以是在非刺激的收缩期期间测量的固有QRS复合物的持续时间。 类似地,第二间隔可以是在刺激的收缩期期间测量的受激QRS复合物的持续时间。
    • 10. 发明授权
    • Method and apparatus for predicting acute response to cardiac resynchronization therapy
    • 用于预测心脏再同步治疗急性反应的方法和装置
    • US07313433B2
    • 2007-12-25
    • US10780794
    • 2004-02-18
    • Yinghong YuJiang DingJulio SpinelliAngelo Aurichio
    • Yinghong YuJiang DingJulio SpinelliAngelo Aurichio
    • A61B5/04
    • A61N1/3627A61N1/3682
    • A method and apparatus for predicting acute response to cardiac resynchronization therapy is disclosed. The method can comprise measuring a first interval during an intrinsic systolic cycle and measuring a second interval during a stimulated systolic cycle. The acute response can be predicted by comparing the percent change in duration between the first interval and the second interval against a pre-determined threshold value. The first and second time intervals can be measured using, for example, a surface ECG or, alternatively, an intracardiac electrogram. In one embodiment, the first interval can be the duration of an intrinsic QRS complex measured during a non-stimulated systolic cycle. Similarly, the second interval can be the duration of a stimulated QRS complex measured during a stimulated systolic cycle.
    • 公开了用于预测心脏再同步治疗的急性反应的方法和装置。 该方法可以包括在本征收缩周期期间测量第一间隔并且在刺激的收缩期期间测量第二间隔。 可以通过将第一间隔和第二间隔之间的持续时间的百分比变化与预定阈值进行比较来预测急性反应。 第一和第二时间间隔可以使用例如表面ECG或者心内电描记图来测量。 在一个实施例中,第一间隔可以是在非刺激的收缩期期间测量的固有QRS复合物的持续时间。 类似地,第二间隔可以是在刺激的收缩期期间测量的受激QRS复合物的持续时间。