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1. 发明授权

US09772408B2 Method and device for extracting scintillation pulse information 有权
公开(公告)号：US09772408B2
公开(公告)日：2017-09-26
申请号：US14112535
申请日：2011-05-10
申请人： Qingguo Xie , Peng Xiao , Xi Wang , Na Li , Yuanbao Chen , Wei Liu
发明人： Qingguo Xie , Peng Xiao , Xi Wang , Na Li , Yuanbao Chen , Wei Liu
IPC分类号： G01T1/20 , G01T1/17
CPC分类号： G01T1/2006 , G01T1/17
摘要： A method for extracting scintillation pulse information includes followed steps: 1. obtaining a peak value of the scintillation pulse in a certain energy spectrum, and setting at least three threshold voltages according to the peak value; 2. determining the time when the scintillation pulse passes through the each threshold voltage, wherein each time value and its corresponding threshold voltage form a sampling point; 3. selecting multiple sampling points as sampling points for reconstructing and reconstructing pulse waveform; 4. obtaining the data of original scintillation pulse by using reconstructed pulse waveform. A device for extracting scintillation pulse information includes a threshold voltage setting module (100), a time sampling module (200), a pulse reconstruction module (300) and an information acquiring module (400).

2. 发明申请

US20140052414A1 METHOD AND DEVICE FOR EXTRACTING SCINTILLATION PULSE INFORMATION 有权
标题翻译：提取激光脉冲信息的方法和装置
公开(公告)号：US20140052414A1
公开(公告)日：2014-02-20
申请号：US14112535
申请日：2011-05-10
申请人： Qingguo Xie , Peng Xiao , Xi Wang , Na Li , Yuanbao Chen , Wei Liu
发明人： Qingguo Xie , Peng Xiao , Xi Wang , Na Li , Yuanbao Chen , Wei Liu
IPC分类号： G01T1/20
CPC分类号： G01T1/2006 , G01T1/17
摘要： A method for extracting scintillation pulse information includes followed steps: 1. obtaining a peak value of the scintillation pulse in a certain energy spectrum, and setting at least three threshold voltages according to the peak value; 2. determining the time when the scintillation pulse passes through the each threshold voltage, wherein each time value and its corresponding threshold voltage form a sampling point; 3. selecting multiple sampling points as sampling points for reconstructing and reconstructing pulse waveform; 4. obtaining the data of original scintillation pulse by using reconstructed pulse waveform. A device for extracting scintillation pulse information includes a threshold voltage setting module (100), a time sampling module (200), a pulse reconstruction module (300) and an information acquiring module (400).
摘要翻译：提取闪烁脉冲信息的方法包括以下步骤：1.获得特定能谱中的闪烁脉冲的峰值，并根据峰值设定至少三个阈值电压; 2.确定闪烁脉冲通过每个阈值电压的时间，其中每个时间值及其相应的阈值电压形成采样点; 3.选择多个采样点作为重建和重构脉搏波形的采样点; 4.通过重建脉冲波形获得原始闪烁脉冲的数据。用于提取闪烁脉冲信息的装置包括阈值电压设定模块（100），时间采样模块（200），脉冲重建模块（300）和信息获取模块（400）。

3. 发明授权

US10930031B2 Synchronization method and system for single event list type data in PET imaging 有权
公开(公告)号：US10930031B2
公开(公告)日：2021-02-23
申请号：US14408935
申请日：2012-08-14
申请人： Qingguo Xie , Yuanbao Chen , Jun Zhu , Xin Chen , Zhongyi Wu , Luyao Wang
发明人： Qingguo Xie , Yuanbao Chen , Jun Zhu , Xin Chen , Zhongyi Wu , Luyao Wang
IPC分类号： G06T11/00 , G01T1/29 , A61B6/03
摘要： A method for synchronizing list-mode data of single events in a PET imaging includes: acquiring list-mode data of single events of each independent detector module, calculating a probability density of time intervals between occurrences of single events in detector module and setting initial parameters, determining detection starting time difference of each detector module with iterative peak searching and graded time window, and performing synchronization correction and coincidence discrimination on the single event data in each detector module based on the detection starting time difference. A system for synchronizing list-mode data of single events in a PET imaging includes: a data acquisition and frequency difference compensation module, an initial parameter setting module, a coarse time scale coincidence module, a fine time scale coincidence module and a data synchronization correction and coincidence discrimination module.

4. 发明授权

US07199370B2 Device and method for digitizing gamma ray energy and characterizing peak time and decay time constant without the use of ADC 有权
标题翻译：用于数字化伽马射线能量并表征峰值时间和衰减时间常数而不使用ADC的装置和方法
公开(公告)号：US07199370B2
公开(公告)日：2007-04-03
申请号：US11097121
申请日：2005-04-04
申请人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
发明人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
IPC分类号： G01T1/164
CPC分类号： G01T1/2985 , A61B6/037
摘要： A device and method used in high resolution positron emission tomography (PET) systems for digitizing gamma ray energy and characterizing peak time and decay time constant, models a voltage pulse generated upon a PET event detection as a fast linearly rising edge followed by a slower exponential decay. The model includes parameters of the voltage pulse that are relevant for PET event detection including a decay constant, a peak voltage value, and a peak time, which are determined from time interval measurements of the voltage pulse. The time interval measurements are made using comparators and counters in an exemplary electronic implementation.
摘要翻译：在用于数字化伽马射线能量并表征峰值时间和衰减时间常数的高分辨率正电子发射断层摄影（PET）系统中使用的装置和方法，将在PET事件检测时产生的电压脉冲建模为快速线性上升沿，随后是较慢的指数衰变。该模型包括与包括衰减常数，峰值电压值和峰值时间相关的PET事件检测的电压脉冲的参数，其由电压脉冲的时间间隔测量确定。在示例性电子实现中使用比较器和计数器进行时间间隔测量。

5. 发明申请

US20060000979A1 Device and method for digitizing pet radiation events 有权
标题翻译：宠物辐射事件数字化的装置和方法
公开(公告)号：US20060000979A1
公开(公告)日：2006-01-05
申请号：US11097153
申请日：2005-04-04
申请人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
发明人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
IPC分类号： G01T1/164
CPC分类号： G01T1/17 , A61B6/037 , G01T1/1647 , G01T1/2985
摘要： A device and method used in the high resolution Positron Emission Tomography (PET) systems for digitizing radiation events for a scintillation camera and a data acquisition system. The device comprises a scintillation digitizer, including a plurality of comparators and amplifiers, two ADCs, and an analyzer for resolving the digital values of radiation events. The method comprises comparing a plurality of analog electric pulses generated upon radiation event detections with a reference voltage corresponding to an energy level of interest, amplifying all of the signals with two groups of coefficients, summing the two groups of amplified signals, digitizing the summed signals, and analyzing the digitized sums to determine digital values corresponding to a plurality of the radiation events.
摘要翻译：用于数字化用于闪烁照相机和数据采集系统的辐射事件的高分辨率正电子发射断层扫描（PET）系统中的装置和方法。该装置包括闪烁数字转换器，包括多个比较器和放大器，两个ADC和用于分辨辐射事件的数字值的分析器。该方法包括将辐射事件检测所产生的多个模拟电脉冲与对应于感兴趣能级的参考电压进行比较，用两组系数放大所有信号，对两组放大信号求和，对相加的信号进行数字化并且分析数字化和以确定对应于多个辐射事件的数字值。

6. 发明申请

US20130087697A1 POSITRON EMISSION TOMOGRAPHY METHOD AND DEVICE WITH APPLICATION ADAPTABILITY 有权
标题翻译： POSITRON排放测量方法和具有应用适应性的设备
公开(公告)号：US20130087697A1
公开(公告)日：2013-04-11
申请号：US13703625
申请日：2011-01-04
申请人： Qingguo Xie , Jingjing Liu
发明人： Qingguo Xie , Jingjing Liu
IPC分类号： G01T1/166
CPC分类号： G01T1/166 , A61B6/037 , A61B6/4258 , A61B6/4275 , A61B6/488 , A61B6/508 , A61B6/5205 , A61B6/545 , A61B6/585
摘要： A positron emission tomography method and a device with application adaptability. The method includes: 1. scanning a tested object initially for obtaining initial activity information of the tested object; 2. programming and adjusting a detector module based on the result of the initial scan so as to obtain a new system structure, and rapidly calibrating the new system structure; 3. performing a scan with the new system structure for obtaining activity information of the tested object; 4. analyzing the activity information of the tested object obtained at step 3. If quality of the activity information can satisfy requirements of the application, the scan is finished; otherwise programming and adjusting the detector module is repeated, rapid calibration is performed, and the activity information of the tested object is obtained again with the new system structure until the activity information satisfies requirements of the application. The device includes a detector module (1), a detector control module (2), an image reconstruction module (3) and a detector programming module (4).
摘要翻译：正电子发射断层摄影方法和具有应用适应性的装置。该方法包括：1.最初扫描被测对象以获得被测对象的初始活动信息; 2.基于初始扫描的结果对检测器模块进行编程和调整，以获得新的系统结构，并快速校准新的系统结构; 3.使用新的系统结构执行扫描以获得被测对象的活动信息; 4.分析在步骤3中获得的测试对象的活动信息。如果活动信息的质量满足应用要求，则扫描结束; 否则重复编程和调整检测器模块，执行快速校准，并且用新的系统结构再次获得测试对象的活动信息，直到活动信息满足应用要求。该装置包括检测器模块（1），检测器控制模块（2），图像重建模块（3）和检测器编程模块（4）。

7. 发明授权

US07342232B2 Device and method for digitizing pet radiation events 有权
标题翻译：宠物辐射事件数字化的装置和方法
公开(公告)号：US07342232B2
公开(公告)日：2008-03-11
申请号：US11097153
申请日：2005-04-04
申请人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
发明人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
IPC分类号： G01T1/164
CPC分类号： G01T1/17 , A61B6/037 , G01T1/1647 , G01T1/2985
摘要： A device and method used in the high resolution Positron Emission Tomography (PET) systems for digitizing radiation events for a scintillation camera and a data acquisition system. The device comprises a scintillation digitizer, including a plurality of comparators and amplifiers, two ADCs, and an analyzer for resolving the digital values of radiation events. The method comprises comparing a plurality of analog electric pulses generated upon radiation event detections with a reference voltage corresponding to an energy level of interest, amplifying all of the signals with two groups of coefficients, summing the two groups of amplified signals, digitizing the summed signals, and analyzing the digitized sums to determine digital values corresponding to a plurality of the radiation events.
摘要翻译：用于数字化用于闪烁照相机和数据采集系统的辐射事件的高分辨率正电子发射断层扫描（PET）系统中的装置和方法。该装置包括闪烁数字转换器，包括多个比较器和放大器，两个ADC和用于分辨辐射事件的数字值的分析器。该方法包括将辐射事件检测所产生的多个模拟电脉冲与对应于感兴趣能级的参考电压进行比较，用两组系数放大所有信号，对两组放大信号求和，对相加的信号进行数字化并且分析数字化和以确定对应于多个辐射事件的数字值。

8. 发明授权

US08664611B2 Positron emission tomography method and device with application adaptability 有权
标题翻译：具有应用适应性的正电子发射断层摄影法和装置
公开(公告)号：US08664611B2
公开(公告)日：2014-03-04
申请号：US13703625
申请日：2011-01-04
申请人： Qingguo Xie , Jingjing Liu
发明人： Qingguo Xie , Jingjing Liu
IPC分类号： G01T1/166 , G12B13/00
CPC分类号： G01T1/166 , A61B6/037 , A61B6/4258 , A61B6/4275 , A61B6/488 , A61B6/508 , A61B6/5205 , A61B6/545 , A61B6/585
摘要： A positron emission tomography method and a device with application adaptability. The method includes: step 1, scanning a tested object for obtaining initial activity information of the tested object; step 2, programming and adjusting a detector module based on the result of the initial scan to obtain a new system structure, and rapidly calibrating the new system structure; step 3, performing a scan with the new system structure for obtaining activity information of the tested object; step 4, analyzing the activity information of the tested object obtained at step 3. If quality of the activity information can satisfy requirements of the application, the scan is finished; otherwise programming and adjusting the detector module is repeated, rapid calibration is performed, and the activity information of the tested object is obtained again with the new system structure until the activity information satisfies requirements.
摘要翻译：正电子发射断层摄影方法和具有应用适应性的装置。该方法包括：步骤1，扫描测试对象以获得测试对象的初始活动信息; 步骤2，根据初始扫描结果编制和调整检测器模块，获得新的系统结构，并快速校准新的系统结构; 步骤3，使用新的系统结构执行扫描以获得被测对象的活动信息; 步骤4，分析在步骤3中获得的测试对象的活动信息。如果活动信息的质量满足应用的要求，则扫描结束; 否则重复编程和调整检测器模块，执行快速校准，并且用新的系统结构再次获得测试对象的活动信息，直到活动信息满足要求。

9. 发明申请

US20050247879A1 Device and method for digitizing gamma ray energy and characterizing peak time and decay time constant without the use of ADC 有权
标题翻译：用于数字化伽马射线能量并表征峰值时间和衰减时间常数而不使用ADC的装置和方法
公开(公告)号：US20050247879A1
公开(公告)日：2005-11-10
申请号：US11097121
申请日：2005-04-04
申请人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
发明人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
IPC分类号： G01T1/161 , A61B6/03 , G01T1/164 , G01T1/17 , G01T1/29
CPC分类号： G01T1/2985 , A61B6/037
摘要： A device and method used in high resolution positron emission tomography (PET) systems for digitizing gamma ray energy and characterizing peak time and decay time constant, models a voltage pulse generated upon a PET event detection as a fast linearly rising edge followed by a slower exponential decay. The model includes parameters of the voltage pulse that are relevant for PET event detection including a decay constant, a peak voltage value, and a peak time, which are determined from time interval measurements of the voltage pulse. The time interval measurements are made using comparators and counters in an exemplary electronic implementation.
摘要翻译：在用于数字化伽马射线能量并表征峰值时间和衰减时间常数的高分辨率正电子发射断层摄影（PET）系统中使用的装置和方法，将在PET事件检测时产生的电压脉冲建模为快速线性上升沿，随后是较慢的指数衰变。该模型包括与包括衰减常数，峰值电压值和峰值时间相关的PET事件检测的电压脉冲的参数，其由电压脉冲的时间间隔测量确定。在示例性电子实现中使用比较器和计数器进行时间间隔测量。

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