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    • 1. 发明申请
    • LV threshold measurement and capture management
    • LV阈值测量和捕获管理
    • US20060149328A1
    • 2006-07-06
    • US11311984
    • 2005-12-20
    • Purvee ParikhJohn StroebelTodd SheldonKaren Kleckner
    • Purvee ParikhJohn StroebelTodd SheldonKaren Kleckner
    • A61N1/365
    • A61N1/3627A61N1/3684A61N1/371
    • The invention provides methods and apparatus for determining in a non-tracking pacing mode (e.g., DDI/R, VVI/R) whether a ventricular pacing stimulus is capturing a paced ventricle, including some or all of the following aspects. For example, increasing a ventricular pacing rate a nominal amount to an overdrive pacing rate higher than a most recent heart rate and evaluating a conduction interval from a first pacing ventricle to a second sensing ventricle and then continuing to monitor the underlying rate to ensure that a threshold testing pacing rate will not exceed a predetermined minimum interval and providing pacing stimulation to the first ventricle and sensing the second ventricle to determine whether the pacing stimulation to the first ventricle was one of sub-threshold and supra-threshold. The methods and apparatus are especially useful in conjunction with ensuring actual delivery of a ventricular pacing regime (e.g., cardiac resynchronization therapy or “CRT”).
    • 本发明提供了用于在非跟踪起搏模式(例如,DDI / R,VVI / R)中确定心室起搏刺激是否捕获节奏心室的方法和装置,包括以下方面中的一些或全部。 例如,将心室起搏速率提高到高于最近心率的超速起搏速率的标称值,并评估从第一起搏心室到第二感测心室的传导间隔,然后继续监测潜在速率,以确保 阈值测试起搏速率不会超过预定的最小间隔,并且向第一脑室提供起搏刺激并且感测第二脑室以确定对第一脑室的起搏刺激是否是子阈值和超阈值之一。 所述方法和装置与确保心室起搏方案(例如,心脏再同步治疗或“CRT”)的实际递送相结合特别有用。
    • 5. 发明申请
    • Method of optimizing cardiac resynchronization therapy using sensor signals of septal wall motion
    • 使用间隔壁运动的传感器信号优化心脏再同步治疗的方法
    • US20050027320A1
    • 2005-02-03
    • US10631551
    • 2003-07-30
    • Robert NehlsTodd Sheldon
    • Robert NehlsTodd Sheldon
    • A61N1/362A61N1/365A61N1/368
    • A61N1/3627A61N1/36542A61N1/3682A61N1/3684
    • The present invention relates to monitoring septal wall motion of the atrial and/or ventricular chambers of a heart for optimizing cardiac pacing intervals based on signals derived from said wall motion. At least one lead of medical device is equipped with a motion sensor adapted to couple to septal tissue. The device receives and may post-process (e.g., suitably filter, rectify and/or integrate) motion signals to determine acceleration, velocity or displacement. During pacing interval optimization the wall motion is measured for many pacing intervals and the pacing interval setting(s) that produce minimal wall motion are implemented for therapy delivery. In addition, the present invention provides methods for periodically determining whether to cease or resume delivery of a bi-ventricular pacing therapy to a patient that may have experienced beneficial reverse remodeling of the heart.
    • 本发明涉及基于从所述壁运动得到的信号来监测心脏的心房和/或室室的间隔壁运动以优化心脏起搏间隔。 医疗装置的至少一个引线配备有适于耦合到间隔组织的运动传感器。 设备接收并且可以后处理(例如,适当地过滤,整流和/或整合)运动信号以确定加速度,速度或位移。 在起搏间期优化过程中,测量了许多起搏间隔的壁运动,并且实施了产生最小壁运动的起搏间隔设置用于治疗递送。 此外,本发明提供了周期性地确定是否停止或恢复对可能经历有益的逆转重建的患者的双心室起搏疗法的递送的方法。
    • 8. 发明申请
    • PERFORMING EXTENDED CAPTURE DETECTION TEST AFTER DETECTING INADEQUATE CAPTURE
    • 在检测到不正确的捕获后执行扩展捕获检测测试
    • US20100198295A1
    • 2010-08-05
    • US12362905
    • 2009-01-30
    • Todd SheldonLynn A. Davenport
    • Todd SheldonLynn A. Davenport
    • A61N1/37
    • A61N1/371
    • Techniques are described for performing an extended capture detection test after detecting inadequate capture during a first capture detection test. An example system includes an implantable medical device that delivers pacing pulses to a patient, that periodically performs a first capture detection test to detect capture or loss of capture of the pacing pulses, and that detects inadequate capture during the first capture detection test, wherein in response to detecting the inadequate capture, the implantable medical device performs a second capture detection test that is longer than the first test. The system also includes a programmer device that programs the implantable medical device and that retrieves data from the implantable medical device corresponding to the second capture detection test. The example system may conserve battery power and prevent loss of current by performing the extended capture detection test only after detection of inadequate capture during the first test.
    • 描述了在第一捕获检测测试中检测到不充分捕获之后进行扩展捕获检测测试的技术。 示例性系统包括向患者传送起搏脉冲的可植入医疗装置,其周期性地执行第一捕获检测测试以检测起搏脉冲的捕获或丢失,并且在第一捕获检测测试期间检测不充分的捕获,其中 响应于检测到不充分的捕获,可植入医疗装置执行比第一测试更长的第二捕获检测测试。 该系统还包括编程器设备,其对可植入医疗设备进行编程,并从与第二捕获检测测试相对应的可植入医疗设备中检索数据。 该示例系统可以仅在第一次测试中检测到不充分的捕获之后执行扩展捕获检测测试来节省电池电力并防止电流损失。