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1. 发明授权

US07875284B2 Methods of manufacturing and modifying taxane coatings for implantable medical devices 有权
标题翻译：制造和修饰可植入医疗器械的紫杉烷涂层的方法
公开(公告)号：US07875284B2
公开(公告)日：2011-01-25
申请号：US11823283
申请日：2007-06-27
申请人： Priscilla Reyes , William F. Moore , Randy Joe Myers , Patrick H. Ruane , Melinda S. Morrell
发明人： Priscilla Reyes , William F. Moore , Randy Joe Myers , Patrick H. Ruane , Melinda S. Morrell
IPC分类号： A61F2/00
CPC分类号： A61K31/335 , A61F2/0095 , A61F2/91 , A61F2250/0067 , A61F2250/0091
摘要： This disclosure relates to endolumenal medical devices coated with a taxane therapeutic agent in one or more solid form(s) having varying dissolution rates. Particularly preferred coatings comprise amorphous paclitaxel, dihydrate paclitaxel, or combinations thereof that provide durable coatings that release paclitaxel over a desired period of time, which can be on the order of hours, days or weeks. Preferred embodiments relate to medical device coatings of paclitaxel, or paclitaxel analogs or derivatives, having one or more polymorph solid forms that provide a prolonged release of paclitaxel within a body vessel without requiring a polymer carrier or barrier layer to achieve the desired rate of paclitaxel elution.
摘要翻译：本公开涉及用一种或多种具有不同溶解速率的固体形式涂覆紫杉烷治疗剂的腔内医疗器械。特别优选的涂层包括无定形紫杉醇，二水合紫杉醇或其组合，其提供耐久性涂层，其在期望的时间段内释放紫杉醇，其可以是数小时，数天或数周的数量级。优选实施方案涉及具有一种或多种多晶型固体形式的紫杉醇或紫杉醇类似物或衍生物的医疗器械涂层，其提供紫杉醇在体内容器内的延长释放，而不需要聚合物载体或阻挡层来实现所需的紫杉醇洗脱速率。

2. 发明授权

US09216277B2 Hemostasis mechanism and method 有权
标题翻译：止血机制及方法
公开(公告)号：US09216277B2
公开(公告)日：2015-12-22
申请号：US13769510
申请日：2013-02-18
申请人： Randy Joe Myers
发明人： Randy Joe Myers
IPC分类号： A61M5/178 , A61M39/06 , A61M25/10 , A61M29/02
CPC分类号： A61M39/0613 , A61M25/10182 , A61M29/02 , A61M2039/062 , A61M2039/0626 , A61M2039/0673
摘要： A hemostasis mechanism includes a housing, and a pressure responsive seal positioned within the housing and having an outer seal surface exposed to a fluid pressure of a port formed in the housing. A pressurization device is in fluid communication with the port, and includes a detent having a release state, and an engaged state holding a plunger of the pressurization device at an advanced position to maintain an increased fluid pressure supplied to the pressure responsive seal to maintain sealing engagement about a transluminal device. Related methodology is also disclosed.
摘要翻译：止血机构包括壳体和位于壳体内的压力响应密封件，并且具有暴露于形成在壳体中的端口的流体压力的外部密封表面。加压装置与端口流体连通，并且包括具有释放状态的止动器和将加压装置的柱塞保持在前进位置的接合状态，以保持提供给压力响应密封件的增加的流体压力以保持密封关于一个经验的设备。还公开了相关方法。

3. 发明授权

US07799201B2 Method of electropolishing medical implants 有权
标题翻译：电抛光医用植入物的方法
公开(公告)号：US07799201B2
公开(公告)日：2010-09-21
申请号：US12732748
申请日：2010-03-26
申请人： Darin G. Schaeffer , Randy Joe Myers
发明人： Darin G. Schaeffer , Randy Joe Myers
IPC分类号： B23H3/02 , C25F7/00
CPC分类号： C25F7/00 , A61F2/91 , A61F2240/00 , C25F3/16
摘要： An electropolishing apparatus and method are provided for polishing stents and other medical implants. The apparatus includes a motor that rotates a roller. The roller continuously rotates the medical implant to be electropolished. One of the advantages of the apparatus and method is that marks generated around the electrical contact between the anode and the medical implant are minimized. In addition, the medical implant is polished more evenly than conventional electropolishing systems.
摘要翻译：提供了用于抛光支架和其他医疗植入物的电抛光装置和方法。该装置包括使滚筒旋转的马达。滚筒将医疗植入物连续旋转以进行电解抛光。该装置和方法的优点之一是使阳极和医用植入物之间的电接触周围产生的标记最小化。此外，医疗植入物比常规电抛光系统更均匀地抛光。

4. 发明申请

US20100181206A1 METHOD OF ELECTROPOLISHING MEDICAL IMPLANTS 有权
标题翻译：电植物植入物的方法
公开(公告)号：US20100181206A1
公开(公告)日：2010-07-22
申请号：US12732748
申请日：2010-03-26
申请人： Darin G. Schaeffer , Randy Joe Myers
发明人： Darin G. Schaeffer , Randy Joe Myers
IPC分类号： C25F3/16 , C25F7/00
CPC分类号： C25F7/00 , A61F2/91 , A61F2240/00 , C25F3/16
摘要： An electropolishing apparatus and method are provided for polishing stents and other medical implants. The apparatus includes a motor that rotates a roller. The roller continuously rotates the medical implant to be electropolished. One of the advantages of the apparatus and method is that marks generated around the electrical contact between the anode and the medical implant are minimized. In addition, the medical implant is polished more evenly than conventional electropolishing systems.
摘要翻译：提供了用于抛光支架和其他医疗植入物的电抛光装置和方法。该装置包括使滚筒旋转的马达。滚筒将医疗植入物连续旋转以进行电解抛光。该装置和方法的优点之一是使阳极和医用植入物之间的电接触周围产生的标记最小化。此外，医疗植入物比常规电抛光系统更均匀地抛光。

5. 发明申请

US20110152715A1 BIOPSY NEEDLE WITH VACUUM ASSIST 审中-公开
标题翻译：生物针与真空辅助
公开(公告)号：US20110152715A1
公开(公告)日：2011-06-23
申请号：US12645106
申请日：2009-12-22
申请人： Dennis J. Delap , Cleve S. Koehler , Robert S. Childress , Randy Joe Myers
发明人： Dennis J. Delap , Cleve S. Koehler , Robert S. Childress , Randy Joe Myers
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B10/0283 , A61B2010/0208
摘要： A surgical cutting device comprises a cannula attached to an actuation mechanism that moves the cannula from a cocked position to a cutting position, a stylet including a distal portion having a sharp distal end, a sample collection region, a vacuum port, and a lumen extending from the vacuum port to the sample collection region such that the sample collection region is in fluid communication with the first vacuum port. When the cannula is in the cocked position, the sample collection region of the stylet is disposed distal of the cannula. The device also includes a fixed volume vacuum source. When cannula is in the cocked position, the vacuum port is not in fluid communication with the fixed volume vacuum source, and when said cannula is in the cutting position, the vacuum port is in fluid communication with the fixed volume vacuum source.
摘要翻译：外科切割装置包括附接到致动机构的套管，其将套管从被压缩位置移动到切割位置，探针包括具有尖锐远端的远侧部分，样本收集区域，真空端口和延伸的管腔从所述真空口到所述样品采集区域，使得所述样品收集区域与所述第一真空口流体连通。当套管处于被压缩位置时，探针的样品收集区域设置在套管的远侧。该装置还包括固定体积的真空源。当套管处于压缩位置时，真空口不与固定体积真空源流体连通，并且当所述套管处于切割位置时，真空口与固定体积的真空源流体连通。

6. 发明申请

US20100049167A1 INTRODUCER SHEATH HAVING REINFORCED DISTAL TAPER 审中-公开
标题翻译：介绍带有加强型密封圈的护套
公开(公告)号：US20100049167A1
公开(公告)日：2010-02-25
申请号：US12194717
申请日：2008-08-20
申请人： Randy Joe Myers
发明人： Randy Joe Myers
IPC分类号： A61M25/01 , B29C65/00
CPC分类号： B29C65/68 , A61M25/0662 , B29C61/006 , B29C63/42 , B29C66/1122 , B29C66/30341 , B29C66/52272 , B29C66/63 , B29C66/71 , B29C66/964 , B29D23/001 , B29K2027/12 , B29K2027/18 , B29K2077/00 , B29K2105/08 , B29K2105/0845 , B29K2305/00 , B29K2995/0049 , B29L2009/00 , B29L2023/007 , B29L2031/008 , Y10T156/1002
摘要： An introducer sheath has an inner liner having a first length comprising a major diameter, a second length comprising a minor diameter, and a tapered third length axially disposed between the first and second lengths. A coil is positioned over the inner liner and spans at least a portion of each of the first, second, and third lengths. An outer jacket is positioned longitudinally around the reinforcing member and the inner liner, and is bonded to the outer surface of the inner liner. The outer jacket has a first length comprising a major diameter, a second length comprising a minor diameter, and a tapered third length axially disposed between the first and second lengths. The outer diameter first, second, and third lengths substantially correspond to and are disposed radially outwardly of the respective inner liner first, second, and third lengths.
摘要翻译：引导器护套具有内衬，其具有第一长度，该第一长度包括大直径，包括小直径的第二长度和轴向地设置在第一和第二长度之间的锥形第三长度。线圈被定位在内衬上并且跨越第一，第二和第三长度中的每一个的至少一部分。外护套纵向设置在加强构件和内衬的周围，并且结合到内衬的外表面。外护套具有第一长度，该第一长度包括大直径，包括小直径的第二长度和轴向地设置在第一和第二长度之间的锥形第三长度。外径第一，第二和第三长度基本上对应于径向向外设置在相应的内衬套第一，第二和第三长度上。

7. 发明申请

US20130253565A1 Hemostasis Mechanism And Method 有权
标题翻译：止血机制及方法
公开(公告)号：US20130253565A1
公开(公告)日：2013-09-26
申请号：US13769510
申请日：2013-02-18
申请人： Randy Joe Myers
发明人： Randy Joe Myers
IPC分类号： A61M29/02
CPC分类号： A61M39/0613 , A61M25/10182 , A61M29/02 , A61M2039/062 , A61M2039/0626 , A61M2039/0673
摘要： A hemostasis mechanism includes a housing, and a pressure responsive seal positioned within the housing and having an outer seal surface exposed to a fluid pressure of a port formed in the housing. A pressurization device is in fluid communication with the port, and includes a detent having a release state, and an engaged state holding a plunger of the pressurization device at an advanced position to maintain an increased fluid pressure supplied to the pressure responsive seal to maintain sealing engagement about a transluminal device. Related methodology is also disclosed.
摘要翻译：止血机构包括壳体和位于壳体内的压力响应密封件，并且具有暴露于形成在壳体中的端口的流体压力的外部密封表面。加压装置与端口流体连通，并且包括具有释放状态的止动器和将加压装置的柱塞保持在前进位置的接合状态，以保持提供给压力响应密封件的增加的流体压力以保持密封关于一个经验的设备。还公开了相关方法。

8. 发明授权

US07879387B2 Process of electrostatically coating a stent on a catheter 有权
标题翻译：在支架上静电涂覆支架的过程
公开(公告)号：US07879387B2
公开(公告)日：2011-02-01
申请号：US12013927
申请日：2008-01-14
申请人： Randy Joe Myers
发明人： Randy Joe Myers
IPC分类号： A61L33/00
CPC分类号： A61L31/16 , A61F2/958 , A61F2250/0067 , A61L31/088 , A61L2300/606
摘要： A process for electrostatically coating a stent on a catheter. A conductor which is permanently affixed to the catheter contacts a stent mounted on the catheter. Conductive ink applied to the catheter may be used as the conductor. An electrical charge is applied to the conductor. The stent is then coated using an electrostatic coating process.
摘要翻译：用于在导管上静电涂覆支架的方法。永久固定在导管上的导体接触安装在导管上的支架。可以使用施加到导管的导电油墨作为导体。对导体施加电荷。然后使用静电涂覆方法涂覆支架。

9. 发明授权

US07799183B2 Electropolishing apparatus and method for medical implants 有权
标题翻译：医疗植入物的电抛光装置及方法
公开(公告)号：US07799183B2
公开(公告)日：2010-09-21
申请号：US11803103
申请日：2007-05-11
申请人： Darin G. Schaeffer , Randy Joe Myers
发明人： Darin G. Schaeffer , Randy Joe Myers
IPC分类号： B23H3/02 , C25F7/00
CPC分类号： C25F7/00 , A61F2/91 , A61F2240/00 , C25F3/16
摘要： An electropolishing apparatus and method are provided for polishing stents and other medical implants. The apparatus includes a motor that rotates a roller. The roller continuously rotates the medical implant to be electropolished. One of the advantages of the apparatus and method is that marks generated around the electrical contact between the anode and the medical implant are minimized. In addition, the medical implant is polished more evenly than conventional electropolishing systems.
摘要翻译：提供了用于抛光支架和其他医疗植入物的电抛光装置和方法。该装置包括使滚筒旋转的马达。滚筒将医疗植入物连续旋转以进行电解抛光。该装置和方法的优点之一是使阳极和医用植入物之间的电接触周围产生的标记最小化。此外，医疗植入物比常规电抛光系统更均匀地抛光。

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