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1. 发明授权

US6162820A Method for removing parasites and in particular ectoparasites of vertebrates, in particular of mammals, and compositions for the implementation of this method 失效
标题翻译：用于去除脊椎动物，特别是哺乳动物的寄生虫，特别是外寄生虫的方法，以及用于实施该方法的组合物
公开(公告)号：US6162820A
公开(公告)日：2000-12-19
申请号：US891047
申请日：1997-07-10
申请人： Philippe Jeannin , Marc Teichner , Philid Reid Timmons , Kenneth Anthony Kukorowski , Bruno Julia , Jean-Yves Vienot , Tai-Teh Wu
发明人： Philippe Jeannin , Marc Teichner , Philid Reid Timmons , Kenneth Anthony Kukorowski , Bruno Julia , Jean-Yves Vienot , Tai-Teh Wu
IPC分类号： B82B1/00 , A01N43/56 , A01N47/02 , A61K31/415
CPC分类号： A01N43/56 , A01N47/02 , A61K31/415 , A01N25/00 , A01N2300/00
摘要： Methods for removing parasites and in particular ectoparasites of vertebrates, in particular of mammals, and compositions for the implementation of this method.Methods for removing parasites of vertebrates, and in particular arthropods, mainly insects and Arachnida, wherein an effectively parasiticidal amount of a compound of formula (I) ##STR1## in particular of fipronil, is administered to the animal via an administration route which makes possible systemic distribution and good absorption.
摘要翻译：用于去除寄生虫，特别是脊椎动物，特别是哺乳动物的寄生虫的方法和用于实施该方法的组合物。用于去除脊椎动物的寄生虫的方法，特别是节肢动物，主要是昆虫和蛛形纲，其中将有效杀寄生虫剂量的式（I）化合物，特别是氟虫腈的化合物通过使得可能的系统分布的给药途径施用于动物，吸收力好

2. 发明授权

US06426333B1 Spot-on formulations for combating parasites 有权
标题翻译：用于防治寄生虫的现货配方
公开(公告)号：US06426333B1
公开(公告)日：2002-07-30
申请号：US09376736
申请日：1999-08-17
申请人： Anne-Marie Huet , Bruno Julia , Jean-Pierre Etchegaray , André Weil , Philippe Jeannin
发明人： Anne-Marie Huet , Bruno Julia , Jean-Pierre Etchegaray , André Weil , Philippe Jeannin
IPC分类号： A61K3170
CPC分类号： A01N43/56 , A01N47/02 , A61K31/70 , A01N2300/00 , A61K2300/00
摘要： In particular this invention provides for spot-on compositions for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: (1) a composition comprising (A) an effective amount of a 1-phenylpyrazole derivative; and/or (B) an effective amount of a macrocyclic lactone antihelmintic or antiparasitic agent; (2) an acceptable liquid carrier vehicle; and (3) optionally, a crystallization inhibitor. The invention also provides for a method of treating parasitic infestations or for the prophylaxis of parasite infestations in mammals or birds which comprises topically applying to said mammal treating parasitic infestations or for the prophylaxis of parasite infestations in mammals or birds which comprises topically applying to said mammal or bird an effective amount of a composition according to the present invention.
摘要翻译：特别地，本发明提供了用于治疗或预防哺乳动物或鸟类寄生虫侵袭的斑点组合物，其包括：（1）包含（A）有效量的1-苯基吡唑衍生物的组合物; 和/或（B）有效量的大环内酯类抗真菌剂或抗寄生虫剂;（2）可接受的液体载体载体; 本发明还提供了一种治疗寄生虫侵袭或预防哺乳动物或鸟类寄生虫侵袭的方法，其包括局部应用于所述哺乳动物治疗寄生虫侵袭或预防寄生虫侵袭哺乳动物或鸟类，其包括向所述哺乳动物或鸟类局部施用有效量的根据本发明的组合物。

3. 发明授权

US06482425B1 Parasiticidal combination 有权
标题翻译：寄生组合
公开(公告)号：US06482425B1
公开(公告)日：2002-11-19
申请号：US09271470
申请日：1999-03-17
申请人： Anne-Marie Huet , Bruno Julia , Jean-Pierre Etchegaray , André Weil , Philippe Jeannin
发明人： Anne-Marie Huet , Bruno Julia , Jean-Pierre Etchegaray , André Weil , Philippe Jeannin
IPC分类号： A01N2532
CPC分类号： A01N43/56 , A01N47/02 , A61K31/70 , A01N43/90 , A61K31/415 , A01N2300/00 , A61K2300/00
摘要： The invention concerns a method and a composition against parasites and particularly ectoparasites and, preferably also endoparasites of small mammals and in particular dogs and cats. The composition contains a compound (A) of formula (I) and a compound (B) consisting of an endectoparasiticide of the macrocylic lactone type.
摘要翻译：本发明涉及针对寄生虫，特别是外寄生虫的方法和组合物，并且优选地还涉及小哺乳动物，特别是狗和猫的寄生虫。该组合物含有式（I）的化合物（A）和由大环内酯型的内消旋杀虫剂组成的化合物（B）。

4. 发明授权

US06962713B2 Spot-on formulations for combating parasites 有权
标题翻译：用于防治寄生虫的现货配方
公开(公告)号：US06962713B2
公开(公告)日：2005-11-08
申请号：US10155397
申请日：2002-05-24
申请人： Anne-Marie Huet , Bruno Julia , Jean-Pierre Etchegaray , André Weil , Philippe Jeannin
发明人： Anne-Marie Huet , Bruno Julia , Jean-Pierre Etchegaray , André Weil , Philippe Jeannin
IPC分类号： A01N43/56 , A01N47/02 , A01N25/04
CPC分类号： A01N43/56 , A01N47/02 , A61K31/70 , A01N2300/00 , A61K2300/00
摘要： In particular this invention provides for spot-on compositions for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: (1) a composition comprising (A) an effective amount of a 1-phenylpyrazole derivative; and/or (B) an effective amount of a macrocyclic lactone antihelmintic or antiparasitic agent; (2) an acceptable liquid carrier vehicle; and (3) optionally, a crystallization inhibitor. The invention also provides for a method of treating parasitic infestations or for the prophylaxis of parasite infestations in mammals or birds which comprises topically applying to said mammal treating parasitic infestations or for the prophylaxis of parasite infestations in mammals or birds which comprises topically applying to said mammal or bird an effective amount of a composition according to the present invention.
摘要翻译：特别地，本发明提供了用于治疗或预防哺乳动物或鸟类寄生虫侵袭的斑点组合物，其包括：（1）包含（A）有效量的1-苯基吡唑衍生物的组合物; 和/或（B）有效量的大环内酯类抗体或抗寄生虫剂; （2）可接受的液体载体载体; 和（3）任选的结晶抑制剂。本发明还提供了一种治疗寄生虫侵袭或预防哺乳动物或鸟类中的寄生虫侵袭的方法，其包括局部施用于所述哺乳动物治疗寄生虫侵袭或预防哺乳动物或鸟类中的寄生虫侵袭，其包括局部施用于所述哺乳动物或鸟类有效量的根据本发明的组合物。

5. 发明授权

US06716442B2 Process and means for the eradication of fleas in the habitats of small mammals 有权
标题翻译：在小型哺乳动物栖息地消灭跳蚤的过程和手段
公开(公告)号：US06716442B2
公开(公告)日：2004-04-06
申请号：US09381794
申请日：1999-12-27
申请人： James S. Hunter , Jean-Pierre Etchegaray , Bruno Julia , Philippe Jeannin
发明人： James S. Hunter , Jean-Pierre Etchegaray , Bruno Julia , Philippe Jeannin
IPC分类号： A01N2502
CPC分类号： A01N43/56 , A01N47/02 , A01N51/00 , A01N25/00 , A01N2300/00
摘要： Method for eradicating fleas in domestic or accommodation premises of a domestic or laboratory mammal is provided. The method involves topically applying, at least monthly, to the domestic or laboratory mammal, a parasitically effective amount of compound of Formula I.
摘要翻译：提供了在家庭或实验室哺乳动物的家庭或住宿场所消灭跳蚤的方法。该方法至少每月至少应用于国内或实验室哺乳动物，即寄生有效量的式I化合物。

6. 发明授权

US6083519A N-phenylpyrazole-based anti-flea and anti-tick collar for cats and dogs 有权
标题翻译：用于猫和狗的基于N-苯基吡唑的防跳蚤和抗蜱衣领
公开(公告)号：US6083519A
公开(公告)日：2000-07-04
申请号：US174598
申请日：1998-10-19
申请人： Philippe Jeannin
发明人： Philippe Jeannin
IPC分类号： A01N25/34 , A01N43/56 , A01N47/02
CPC分类号： A01N43/56 , A01N47/02
摘要： Collar or other external device for a pet, in particular a cat or dog, made of a matrix in which is incorporated from 0.1 to 40% by weight, preferably from 1 to 15% by weight, relative to the collar, of a substance which is active against ectoparasites such as fleas and ticks, this active substance being formed of at least one compound corresponding to formula (I) below: ##STR1## this collar or other external device being designed to ensure more than 6 months of efficacy against fleas and more than 3 months of efficacy against ticks, the efficacy being maintained for several weeks even if the collar or other external device is taken off or lost or if there is a variation in the release of the compound.
摘要翻译：用于由基质制成的宠物，特别是猫或狗的衣领或其他外部装置，其中相对于衣领以0.1至40重量％，优选1至15重量％的重量掺入对于外寄生物如跳蚤和蜱是有活性的，该活性物质由至少一种对应于下式（I）的化合物形成：该衣领或其他外部装置被设计成确保超过6个月对跳蚤的功效，并且超过3 几个月对蜱的功效，即使衣领或其他外部装置脱落或丢失，或化合物的释放有变化，效力也保持数周。

7. 发明授权

US06413542B1 Direct pour-on antiparasitic skin solution and methods for treating, preventing and controlling myasis 有权
标题翻译：直接注射抗寄生虫皮肤溶液及治疗，预防和控制瘀血的方法
公开(公告)号：US06413542B1
公开(公告)日：2002-07-02
申请号：US09450186
申请日：1999-11-29
申请人： Jean-Pierre Etchegaray , Philippe Jeannin
发明人： Jean-Pierre Etchegaray , Philippe Jeannin
IPC分类号： A01N2502
CPC分类号： A61K31/4439 , A01N43/56 , A01N47/02 , A61K31/415 , A01N2300/00 , A61K2300/00
摘要： The direct pour-on skin solution intended to eliminate parasites, in particular Boophilus microplus, from cattle and sheep comprises from 0.05 to 25%, preferably from 0.05 to 10%, and in particular from 0.1 to 2% weight/volume, relative to the total solution, of a compound of formula (I): in a formulation at low volume, designed to release the compound (I) onto the skin and the hairs for a contact action against parasites.
摘要翻译：用于消除来自牛和绵羊的寄生虫，特别是Boophilus microplus的直接倾倒皮肤溶液相对于牛和羊来说包含0.05至25％，优选0.05至10％，特别是0.1至2％重量/体积式（I）化合物的总溶液：在低体积的制剂中，设计用于将化合物（I）释放到皮肤和毛发上用于与寄生虫接触的作用。

8. 发明授权

US06358988B1 Process and composition for the antiparasitic treatment of the surroundings of animals 失效
标题翻译：用于动物周围环境的反寄生虫治疗的过程和组成
公开(公告)号：US06358988B1
公开(公告)日：2002-03-19
申请号：US09230283
申请日：1999-04-23
申请人： Philippe Jeannin , James William Smith , Samuel Perry Yenne
发明人： Philippe Jeannin , James William Smith , Samuel Perry Yenne
IPC分类号： H01N4356
CPC分类号： A01N47/02 , A01N43/56 , A01N47/22 , A01N25/00 , A01N2300/00
摘要： Processes for the antiparasitic control of darkling beetles utilizing 1-arylpyrazole insecticides and for applying said insecticides to animal litter, especially for animal rearing, are described. Also described are mixtures of carbaryl and 1-arylpyrazole insecticides.
摘要翻译：描述了使用1-芳基吡唑杀虫剂和将所述杀虫剂施用于动物垫料，特别是用于动物饲养的暗甲虫的防寄生虫防治方法。还描述了甲氰酰和1-芳基吡唑杀虫剂的混合物。

9. 发明授权

US5885607A N-phenylpyrazole-based anti-flea and anti-tick external device for cats and dogs 失效
标题翻译：用于猫和狗的基于N-苯基吡唑的防跳蚤和抗蜱外部装置
公开(公告)号：US5885607A
公开(公告)日：1999-03-23
申请号：US863182
申请日：1997-05-27
申请人： Philippe Jeannin
发明人： Philippe Jeannin
IPC分类号： A01N25/34 , A01N43/56 , A01N47/02
CPC分类号： A01N43/56 , A01N47/02
摘要： Collar or other external device for a pet, in particular a cat or dog, made of a matrix in which is incorporated from 0.1 to 40% by weight, preferably from 1 to 15 % by weight, relative to the external device, of a substance which is active against ectoparasites such as fleas and ticks, this active substance being formed of at least one compound corresponding to formula (I) below: ##STR1## this collar or other external device being designed to ensure more than 6 months of efficacy against fleas and more than 3 months of efficacy against ticks, the efficacy being maintained for several weeks even if the collar or other external device is taken off or lost or if there is a variation in the release of the compound.
摘要翻译：用于宠物，特别是猫或狗的衣领或其他外部装置，其由相对于外部装置的0.1至40重量％，优选1至15重量％的基质掺入的基质该活性物质由至少一种对应于下式（I）的化合物形成：（I）该衣领或其它外部装置被设计成确保超过6个月的针对蚤的功效以及超过3个月对蜱的功效，即使衣领或其他外部装置脱落或丢失，或化合物的释放有所变化，效力也保持数周。

10. 发明授权

US06797724B2 Direct spot-on antiparasitic skin solution for domestic animals 有权
标题翻译：用于家畜的直接点对抗寄生虫皮肤溶液
公开(公告)号：US06797724B2
公开(公告)日：2004-09-28
申请号：US10120691
申请日：2002-04-11
申请人： Jean-Pierre Etchegaray , Philippe Jeannin
发明人： Jean-Pierre Etchegaray , Philippe Jeannin
IPC分类号： A01N4356
CPC分类号： A61K31/4439 , A01N43/56 , A01N47/02 , A61K31/415 , A01N2300/00 , A61K2300/00
摘要： A spot-on composition for the treatment or protection of a domestic animal against parasitic infestation comprising, (a) an insecticidal active substance of the formula (X): (b) an organic solvent; and (c) a vehicle; and (d) an emollient; wherein the composition comprises from 0.05 to 25% weight/volume of the compound of formula (X), and the compound of formula (X) is applied in a dose between 0.1 and 2 mg/kg animal weight.
摘要翻译：用于治疗或保护家畜免于寄生虫侵袭的斑点组合物，其包含：（a）式（X）的杀虫活性物质:( b）有机溶剂; 及（c）车辆; 和（d）润肤剂; 其中所述组合物包含0.05至25重量％体积的式（X）化合物，并且式（X）化合物以0.1至2mg / kg动物重量的剂量施用。

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