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1. 发明授权

US5970164A System and method for diagnosis of living tissue diseases 失效
标题翻译：用于诊断活组织疾病的系统和方法
公开(公告)号：US5970164A
公开(公告)日：1999-10-19
申请号：US803328
申请日：1997-02-21
申请人： Philippe Bamberger , Isaac Leichter , Scott Fields , Yuriy Alexandrov , Vlad Mendelevich
发明人： Philippe Bamberger , Isaac Leichter , Scott Fields , Yuriy Alexandrov , Vlad Mendelevich
IPC分类号： G06T5/00 , G06T5/40 , G06K9/00 , A61B6/04 , G06F15/00 , G06K9/38
CPC分类号： G06T7/0081 , G06T5/009 , G06T5/40 , G06T2207/10008 , G06T2207/10116 , G06T2207/30068 , G06T2207/30096
摘要： A system and method for diagnosis of living tissue diseases is described. The system includes a computer device for controlling its operation. An operator control device is coupled to the computer device. A viewing screen is coupled to the computer device for displaying digitized images of the living tissue. The operator, using the control device, selects desired portions of the digitized image for further image enhancement according to a desired image enhancement feature selectable from a plurality of image enhancement features. The image enhancement features include any combination of grey scale stretching, contrast enhancement based on logarithmic histogram equalization, spot enhancement and magnification. The system further includes means for visualization and quantification of micro-calcifications, and means for visualization and quantification of mass spiculations.
摘要翻译：描述了用于诊断活组织疾病的系统和方法。该系统包括用于控制其操作的计算机设备。操作员控制装置耦合到计算机装置。观察屏幕耦合到计算机设备，用于显示生物体组织的数字化图像。使用控制装置的操作者根据从多个图像增强特征中可选择的期望的图像增强特征来选择数字化图像的期望部分用于进一步的图像增强。图像增强特征包括基于对数直方图均衡，斑点增强和放大的灰度拉伸，对比度增强的任何组合。该系统还包括用于微钙化的可视化和定量的装置，以及用于大量刺激的可视化和定量的装置。

2. 发明授权

US5854851A System and method for diagnosis of living tissue diseases using digital image processing 失效
标题翻译：使用数字图像处理诊断活组织疾病的系统和方法
公开(公告)号：US5854851A
公开(公告)日：1998-12-29
申请号：US289381
申请日：1994-08-11
申请人： Philippe Bamberger , Isaac Leichter , Scott Fields
发明人： Philippe Bamberger , Isaac Leichter , Scott Fields
IPC分类号： G06T5/40 , G06K9/00
CPC分类号： G06T5/008 , G06T5/40 , G06T2207/30068
摘要： A system and method for diagnosis of living tissue diseases is described. The system includes a computer device for controlling its operation. An operator control device is coupled to the computer device. A viewing screen is coupled to the computer device for displaying digitized images of the living tissue. The operator, using the control device, selects desired portions of the digitized image for further image enhancement according to a desired image enhancement feature selectable from a plurality of image enhancement features. The image enhancement features include any combination of grey scale stretching, contrast enhancement based on logarithmic histogram equalization, spot enhancement and magnification. The system further includes means for visualization and quantification of micro-calcifications, and means for visualization and quantification of mass spiculations.
摘要翻译：描述了用于诊断活组织疾病的系统和方法。该系统包括用于控制其操作的计算机设备。操作员控制装置耦合到计算机装置。观察屏幕耦合到计算机设备，用于显示生物体组织的数字化图像。使用控制装置的操作者根据从多个图像增强特征中可选择的期望图像增强特征来选择数字化图像的期望部分以进一步增强图像。图像增强特征包括基于对数直方图均衡，斑点增强和放大的灰度拉伸，对比度增强的任何组合。该系统还包括用于微钙化的可视化和定量的装置，以及用于大量刺激的可视化和定量的装置。

3. 发明授权

US5946407A System and method for scanning medical images using adjustable exposure time and brightness 失效
标题翻译：使用可调曝光时间和亮度扫描医学图像的系统和方法
公开(公告)号：US5946407A
公开(公告)日：1999-08-31
申请号：US811783
申请日：1997-03-06
申请人： Philippe Bamberger , Isaac Leichter , Scott Fields
发明人： Philippe Bamberger , Isaac Leichter , Scott Fields
IPC分类号： G06T5/40 , G06K9/00
CPC分类号： G06T5/008 , G06T5/40 , G06T2207/30068
摘要： A system and method for diagnosis of living tissue diseases is described. The system includes a computer device for controlling its operation. An operator control device is coupled to the computer device. A viewing screen is coupled to the computer device for displaying digitized images of the living tissue. The operator, using the control device, selects desired portions of the digitized image for further image enhancement according to a desired image enhancement feature selectable from a plurality of image enhancement features. The image enhancement features include any combination of grey scale stretching, contrast enhancement based on logarithmic histogram equalization, spot enhancement and magnification. The system further includes means for visualization and quantification of micro-calcifications, and means for visualization and quantification of mass spiculations.
摘要翻译：描述了用于诊断活组织疾病的系统和方法。该系统包括用于控制其操作的计算机设备。操作员控制装置耦合到计算机装置。观察屏幕耦合到计算机设备，用于显示生物体组织的数字化图像。使用控制装置的操作者根据从多个图像增强特征中可选择的期望的图像增强特征来选择数字化图像的期望部分用于进一步的图像增强。图像增强特征包括基于对数直方图均衡，斑点增强和放大的灰度拉伸，对比度增强的任何组合。该系统还包括用于微钙化的可视化和定量的装置，以及用于大量刺激的可视化和定量的装置。

4. 发明授权

US07418119B2 Display for computer-aided evaluation of medical images and for establishing clinical recommendation therefrom 有权
标题翻译：显示计算机辅助评估医学图像和建立临床推荐
公开(公告)号：US07418119B2
公开(公告)日：2008-08-26
申请号：US10754622
申请日：2004-01-12
申请人： Isaac Leichter , Philippe Bamberger , Richard Lederman
发明人： Isaac Leichter , Philippe Bamberger , Richard Lederman
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06F19/00 , G06K9/033 , G06K2209/05 , G06Q50/22 , G06T2207/30068
摘要： A method for displaying a computer-generated determination of the overall likelihood of malignancy in a mammogram lesion. The method requires providing a digitized image of a mammogram, displaying the digitized image, and selecting a region of interest directly on the displayed digitized image. The digitized image is then processed so that classifier data of the lesion in the user-selected region of interest are generated and displayed. The overall likelihood of malignancy is generated from the classifier data and also displayed. A clinical recommendation for further assessing the lesion is derived from the overall evaluation of malignancy and presented to the user. A system for displaying a determination of the overall likelihood of malignancy in a mammogram lesion and for presenting a clinical recommendation to the user is also provided. A method for integrating the overall likelihood of malignancy with a physician's independent score for the lesion is discussed.
摘要翻译：一种用于显示计算机产生的确定乳腺X线照片损伤中恶性肿瘤的总体可能性的方法。该方法需要提供乳房X线照片的数字化图像，显示数字化图像，并且在显示的数字化图像上直接选择感兴趣区域。然后处理数字化图像，使得生成并显示用户选择的感兴趣区域中的病变的分类器数据。从分类数据生成恶性肿瘤的总体可能性，并显示。进一步评估病变的临床推荐来自恶性肿瘤的总体评估并呈现给用户。还提供了一种用于显示乳房X线照片损伤中的恶性肿瘤的整体可能性的确定并向用户呈现临床推荐的系统。讨论了将恶性肿瘤的整体可能性与病灶的医师独立评分相结合的方法。

5. 发明授权

US07203350B2 Display for computer-aided diagnosis of mammograms 有权
标题翻译：显示乳腺X线照片的计算机辅助诊断
公开(公告)号：US07203350B2
公开(公告)日：2007-04-10
申请号：US10284213
申请日：2002-10-31
申请人： Isaac Leichter , Philippe Bamberger , Boris Novak
发明人： Isaac Leichter , Philippe Bamberger , Boris Novak
IPC分类号： G06K9/00 , A61B5/55 , A61B6/00
CPC分类号： G06K9/033 , G06K2209/05 , G06T7/0012 , G06T2207/30068
摘要： A method for displaying a computer-generated determination of the likelihood of malignancy in a mammogram lesion. The method requires providing a digitized image of a mammogram, displaying the digitized image, and selecting a region of interest directly on the displayed digitized image. The digitized image is then processed so that classifier data of the lesion in the user-selected region of interest are generated and displayed. A system for displaying a determination of the likelihood of malignancy in a mammogram lesion. The system includes a display for presenting a digitized mammogram and an input device in communication with the display for selectably indicating a region of interest on the displayed mammogram. The system also includes a processor for generating classifier data related to a characterization feature within the region of interest. The classifier data is presented on the display.
摘要翻译：一种用于显示计算机产生的在乳房X线照片损伤中恶性肿瘤可能性的确定的方法。该方法需要提供乳房X线照片的数字化图像，显示数字化图像，并且在显示的数字化图像上直接选择感兴趣区域。然后处理数字化图像，使得生成并显示用户选择的感兴趣区域中的病变的分类器数据。用于显示乳房X线照片损伤中恶性肿瘤可能性的确定的系统。该系统包括用于呈现数字化乳房X线照片的显示器和与显示器通信的输入设备，用于可选地指示所显示的乳房X线照片上的感兴趣区域。该系统还包括用于生成与感兴趣区域内的表征特征相关的分类器数据的处理器。分类器数据显示在显示屏上。

6. 发明申请

US20050111721A1 Workstation for computerized analysis in mammography and methods for use thereof 审中-公开
标题翻译：乳房X线照相术计算机分析工作站及其使用方法
公开(公告)号：US20050111721A1
公开(公告)日：2005-05-26
申请号：US10722307
申请日：2003-11-25
申请人： Philippe Bamberger , Nicolas Merlet , Gil Guggenheim
发明人： Philippe Bamberger , Nicolas Merlet , Gil Guggenheim
IPC分类号： G06F19/00 , G06K9/00 , G06K9/36 , G06T7/00
CPC分类号： G06T7/0012 , G06T2207/30068
摘要： A method for determining if the digitized image of a scanned film mammogram represents a left or right breast. The method also determines if the projection therein represents a craniocaudal projection or mediolateral oblique projection. Additionally, the method allows for automatic ordering of a set of digitized images according to a pre-selected order. A method is also provided for determining if the digitized image of a scanned film mammogram represents an improperly flipped or rotated view, automatically correcting the problem. Additionally the present invention provides for easy restarting of a workstation when the processing and/or scanning systems crash or an examination fails.
摘要翻译：一种用于确定扫描的胶片乳腺X线照片的数字化图像是否表示左乳房或右乳房的方法。该方法还确定其中的突出物是否表示头颈部突起或中间向斜投影。此外，该方法允许根据预先选择的顺序自动排序一组数字化图像。还提供了一种用于确定扫描的胶片乳房X线照片的数字化图像是否表示不正确翻转或旋转视图的方法，自动地纠正该问题。此外，本发明提供了当处理和/或扫描系统崩溃或检查失败时容易重新启动工作站。

7. 发明申请

US20080107323A1 Computer Diagnosis of Malignancies and False Positives 有权
标题翻译：电脑诊断恶性肿瘤和假阳性
公开(公告)号：US20080107323A1
公开(公告)日：2008-05-08
申请号：US11876851
申请日：2007-10-23
申请人： Eliahu Ratner , Philippe Bamberger
发明人： Eliahu Ratner , Philippe Bamberger
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06F19/00 , G06T7/30 , G06T2207/30068
摘要： A method for diagnosing malignancy of suspect regions in a 2D imaging projection of a body organ of a subject comprising the steps of: normalizing the image projection to map regions thereof onto a standard shape; extracting location of regions mapped on the standard shape and using normalized position of a suspect region to assess likelihood that it is malignant.
摘要翻译：一种用于诊断对象的身体器官的2D成像投影中的可疑区域的恶性的方法，包括以下步骤：将图像投影归一化以将其区域映射到标准形状; 提取在标准形状上映射的区域的位置，并使用可疑区域的归一化位置来评估其恶性的可能性。

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