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1. 发明授权

US08670810B2 Regional oximetry analog front end 有权
标题翻译：区域血氧仪模拟前端
公开(公告)号：US08670810B2
公开(公告)日：2014-03-11
申请号：US12794420
申请日：2010-06-04
申请人： Philip O. Isaacson
发明人： Philip O. Isaacson
IPC分类号： A61B5/05
CPC分类号： A61B5/14552 , H03F3/087 , H03F3/45475 , H03F2200/261
摘要： An apparatus includes a first amplifier having a first input coupled to a first optical detector. The first amplifier includes a first output corresponding to a logarithm of the first input. The apparatus includes a second amplifier having a second input coupled to a second optical detector and having a second output corresponding to a logarithm of the second input. The apparatus includes a differential amplifier configured to amplify a difference between the first output and the second output.
摘要翻译：一种装置包括具有耦合到第一光学检测器的第一输入的第一放大器。第一放大器包括对应于第一输入的对数的第一输出。该装置包括第二放大器，其具有耦合到第二光学检测器的第二输入端，并具有对应于第二输入的对数的第二输出。该装置包括：差分放大器，被配置为放大第一输出和第二输出之间的差。

2. 发明申请

US20090299675A1 LED CONTROL UTILIZING AMBIENT LIGHT OR SIGNAL QUALITY 审中-公开
标题翻译： LED控制利用环境光或信号质量
公开(公告)号：US20090299675A1
公开(公告)日：2009-12-03
申请号：US12476687
申请日：2009-06-02
申请人： Philip O. Isaacson , Josh D. Schilling
发明人： Philip O. Isaacson , Josh D. Schilling
IPC分类号： G06F19/00
CPC分类号： A61B5/14551 , A61B5/7221 , A61B5/7242 , A61B2560/0209
摘要： A system and method for controlling a light emitting device for an optical sensor based on signal quality and/or power consumption requirements. Drive current and/or integration time is controlled as a function of detected ambient light or signal quality. As the signal quality decreases the drive current or integration time can be adjusted to provide a more usable signal. If after some criteria for reduction, such as “time on” or high signal quality, then the drive current can be decreased.
摘要翻译：一种用于基于信号质量和/或功率消耗要求来控制用于光学传感器的发光器件的系统和方法。作为检测到的环境光或信号质量的函数控制驱动电流和/或积分时间。随着信号质量的降低，可以调节驱动电流或积分时间以提供更可用的信号。如果经过一些减少的标准，例如“开启时间”或高信号质量，则可以减小驱动电流。

3. 发明申请

US20100312080A1 REGIONAL OXIMETRY ANALOG FRONT END 有权
标题翻译：区域氧化物模拟前端
公开(公告)号：US20100312080A1
公开(公告)日：2010-12-09
申请号：US12794420
申请日：2010-06-04
申请人： Philip O. Isaacson
发明人： Philip O. Isaacson
IPC分类号： A61B5/1455 , H03F3/68 , H03F3/45
CPC分类号： A61B5/14552 , H03F3/087 , H03F3/45475 , H03F2200/261
摘要： An apparatus includes a first amplifier having a first input coupled to a first optical detector. The first amplifier includes a first output corresponding to a logarithm of the first input. The apparatus includes a second amplifier having a second input coupled to a second optical detector and having a second output corresponding to a logarithm of the second input. The apparatus includes a differential amplifier configured to amplify a difference between the first output and the second output.
摘要翻译：一种装置包括具有耦合到第一光学检测器的第一输入的第一放大器。第一放大器包括对应于第一输入的对数的第一输出。该装置包括第二放大器，其具有耦合到第二光学检测器的第二输入端，并具有对应于第二输入的对数的第二输出。该装置包括：差分放大器，被配置为放大第一输出和第二输出之间的差。

4. 发明申请

US20100130840A1 OPTICAL SENSOR PATH SELECTION 有权
标题翻译：光传感器路径选择
公开(公告)号：US20100130840A1
公开(公告)日：2010-05-27
申请号：US12618120
申请日：2009-11-13
申请人： Philip O. Isaacson
发明人： Philip O. Isaacson
IPC分类号： A61B5/1455
CPC分类号： A61B5/14553 , A61B5/14552 , A61B5/6814 , A61B2503/045 , A61B2562/0233 , A61B2562/0242 , A61B2562/043 , A61B2562/228
摘要： A device includes a sensor for measuring a parameter for tissue. The sensor includes a plurality of optical elements including a plurality of detectors and at least one emitter. Separation distances between the various optical elements are selected based on a depth corresponding to a region of interest in the tissue and based on a depth corresponding to an exclusion region in the tissue.
摘要翻译：一种装置包括用于测量组织参数的传感器。传感器包括多个光学元件，包括多个检测器和至少一个发射器。基于对应于组织中的感兴趣区域的深度并且基于对应于组织中的排除区域的深度来选择各种光学元件之间的分离距离。

5. 发明授权

US4773422A Single channel pulse oximeter 失效
标题翻译：单通道脉搏血氧仪
公开(公告)号：US4773422A
公开(公告)日：1988-09-27
申请号：US44329
申请日：1987-04-30
申请人： Philip O. Isaacson , David W. Gadtke , Vernon D. Heidner , Neal F. Nordling
发明人： Philip O. Isaacson , David W. Gadtke , Vernon D. Heidner , Neal F. Nordling
IPC分类号： A61B5/00
CPC分类号： A61B5/14551
摘要： An electronic apparatus for sensing the percentage of different blood constituents in arterial blood. Light of a plurality of separate wave lengths is sequentially made to pass through a portion of the body, either by direct transmission or scattering so that the pulsatile blood flow modulates the intensity of the light. A signal processing circuit functioning in accordance with the Lambert-Beer Law is used to determine the percentage of different blood constituents from the fluctuations component of the logarithm of the light absorption. The sampling of the separate wave lengths is time-multiplexed through a common channel, thus obviating the need for a separate channel of similar electronics for each constituent to be monitored. The signal processing circuitry is also effective to compensate for noise due to ambient light or other stray sources, thus improving the overall accuracy.
摘要翻译：一种用于感测动脉血中不同血液成分的百分比的电子设备。依次通过直接透射或散射使多个分开的波长的光通过身体的一部分，使得脉动血流调制光的强度。根据朗伯 - 比尔定律起作用的信号处理电路用于确定不同血液成分与光吸收对数的波动分量的百分比。通过公共通道对单独波长的采样进行时间复用，从而避免了对于要监视的每个组分的类似电子设备的单独通道的需要。信号处理电路还能够有效地补偿由于环境光或其他杂散源引起的噪声，从而提高整体精度。

6. 发明授权

US09700249B2 Non-invasive optical sensor 有权
公开(公告)号：US09700249B2
公开(公告)日：2017-07-11
申请号：US12423985
申请日：2009-04-15
申请人： Timothy L. Johnson , Franz Ulrich , Philip O. Isaacson
发明人： Timothy L. Johnson , Franz Ulrich , Philip O. Isaacson
IPC分类号： A61B5/1455 , A61B5/00
CPC分类号： A61B5/14553 , A61B5/14552 , A61B5/6825 , A61B5/6833 , A61B5/6843
摘要： An apparatus includes a sensor body, a circuit board, a cable, at least one light emitting device, and at least one photodetector. The circuit board is enclosed within the sensor body and includes at least one conductive trace and at least one aperture. The cable is coupled to the at least one conductive trace. The cable includes a shield conductor and a signal conductor. The at least one light emitting device is coupled to the circuit board and is configured to emit light into a tissue. The at least one photodetector includes a planar active area coupled to the circuit board and is configured to provide an output signal based on light detected by the active area. The planar active area is aligned with the aperture. The output signal is coupled to the cable.

7. 发明授权

US09480408B2 Home uterine activity monitoring 有权
标题翻译：家庭子宫活动监测
公开(公告)号：US09480408B2
公开(公告)日：2016-11-01
申请号：US13484888
申请日：2012-05-31
申请人： Philip O. Isaacson , Bryant Austin Jones , Timothy L. Johnson
发明人： Philip O. Isaacson , Bryant Austin Jones , Timothy L. Johnson
IPC分类号： G01L1/00 , G01L5/00 , A61B5/03 , A61B5/00
CPC分类号： A61B5/033 , A61B5/6831 , A61B5/6843
摘要： A device includes a guard member, at least one bias sensor, a display, and a measurement sensor. The guard member includes an aperture on an axis. The at least one bias sensor is coupled to the guard member. The at least one bias sensor is configured to provide a bias signal corresponding to a bias force on the guard member. The bias force is aligned parallel with the axis. The display is coupled to the at least one bias sensor and is configured to provide a visible indication of the bias force. The measurement sensor is configured to provide an output signal corresponding to a measured force proximate the aperture.
摘要翻译：一种装置包括防护件，至少一个偏置传感器，显示器和测量传感器。防护构件包括轴上的孔。所述至少一个偏置传感器联接到所述防护构件。所述至少一个偏置传感器被配置为提供对应于所述防护构件上的偏置力的偏置信号。偏压力与轴平行。显示器耦合到至少一个偏置传感器并且被配置为提供偏置力的可见指示。测量传感器被配置为提供对应于靠近孔径的被测力的输出信号。

8. 发明授权

US08725226B2 Optical sensor path selection 有权
标题翻译：光学传感器路径选择
公开(公告)号：US08725226B2
公开(公告)日：2014-05-13
申请号：US12618120
申请日：2009-11-13
申请人： Philip O. Isaacson
发明人： Philip O. Isaacson
IPC分类号： A61B5/00
CPC分类号： A61B5/14553 , A61B5/14552 , A61B5/6814 , A61B2503/045 , A61B2562/0233 , A61B2562/0242 , A61B2562/043 , A61B2562/228
摘要： A device includes a sensor for measuring a parameter for tissue. The sensor includes a plurality of optical elements including a plurality of detectors and at least one emitter. Separation distances between the various optical elements are selected based on a depth corresponding to a region of interest in the tissue and based on a depth corresponding to an exclusion region in the tissue.
摘要翻译：一种装置包括用于测量组织参数的传感器。传感器包括多个光学元件，包括多个检测器和至少一个发射器。基于对应于组织中的感兴趣区域的深度并且基于对应于组织中的排除区域的深度来选择各种光学元件之间的分离距离。

9. 发明申请

US20080221420A1 Fetal Pulse Oximetry and ECG Sensor 审中-公开
标题翻译：胎儿血氧饱和度和心电图传感器
公开(公告)号：US20080221420A1
公开(公告)日：2008-09-11
申请号：US11683777
申请日：2007-03-08
申请人： Vladimir Grubac , Peter R. Rosendahl , Douglas R. Maser , Philip O. Isaacson
发明人： Vladimir Grubac , Peter R. Rosendahl , Douglas R. Maser , Philip O. Isaacson
IPC分类号： A61B5/1464
CPC分类号： A61B5/0448 , A61B5/0205 , A61B5/14542 , A61B5/1464 , A61B5/4362 , A61B5/6882 , A61B2503/02
摘要： A medical device configured to be temporarily secured at a tissue field, such as a fetal skull, via a spiral probe. The spiral probe functions to both secure the sensor in place and provide an electrode for ECG purposes. The spiral probe is non-uniform and includes one or more of a stop element, a cross bar element and a collapsed portion adapted to engage tissue after a predetermined rotation of the probe into the tissue field. The probe diameter can expand with an increase in torque applied to a drive rod, leading to disengagement of the drive rod from the probe. The spiral probe and drive rod may define a detent mechanism whereby upon reaching a predetermined torque the drive rod is disengaged from the probe and freely rotates without further entry of the spiral probe into the tissue field.
摘要翻译：一种被配置为经由螺旋探针临时固定在诸如胎儿头骨的组织场的医疗装置。螺旋探头用于将传感器固定到位，并提供用于ECG目的的电极。螺旋探针是不均匀的，并且包括止动元件，横杆元件和折叠部分中的一个或多个，其适于在将探针预定旋转到组织区域中之后接合组织。探头直径可以随施加在驱动杆上的扭矩的增加而膨胀，导致驱动杆与探头分离。螺旋探针和驱动杆可以限定制动机构，由此当达到预定扭矩时，驱动杆从探头脱离并自由旋转，而不再进一步将螺旋探针进入组织区域。

10. 发明授权

US5800349A Offset pulse oximeter sensor 失效
标题翻译：偏移脉搏血氧计传感器
公开(公告)号：US5800349A
公开(公告)日：1998-09-01
申请号：US970232
申请日：1997-11-14
申请人： Philip O. Isaacson , David W. Gadtke
发明人： Philip O. Isaacson , David W. Gadtke
IPC分类号： A61B5/00
CPC分类号： A61B5/6816 , A61B5/14552 , A61B5/6826 , A61B5/6829 , A61B5/6838
摘要： In accordance with the present invention, a transmittance pulse oximeter sensor having an emitter that is offset from the detector. Offsetting the emitter and detector allows more light to pass through a thin tissue pulsating arterial bed than does a vertically aligned design. The offset between the emitter and the detector increases the effective arterial blood component without increasing artifact. Thus, the arterial blood component strength relative to the artifact strength is increased resulting in an improved signal and an improved pulse oximetry reading. The offset pulse oximetry sensor is especially important in veterinary pulse oximeter applications where it is necessary to monitor small animals whose optimal pulse oximetry location is a thin tissue tongue. The offset pulse oximetry sensor is additionally important in the realm of human medicine where often the optimal position for a pulse oximeter sensor is a thin tissue ear or an infant's thin tissue finger or toe.
摘要翻译：根据本发明，具有偏离检测器的发射体的透射率脉搏血氧计传感器。偏移发射器和检测器允许更多的光穿过薄组织脉动动脉床比垂直对齐的设计。发射器和检测器之间的偏移增加了有效的动脉血液成分，而不增加神经。因此，相对于伪影强度的动脉血液成分强度增加，导致改善的信号和改进的脉搏血氧饱和度读数。偏移脉搏血氧饱和度传感器在兽医脉搏血氧仪应用中尤其重要，在这些应用中，需要监测其最佳脉搏血氧饱和度位置为薄组织舌的小动物。偏移脉搏血氧饱和度传感器在人类医学的领域中是另外重要的，其中脉搏血氧计传感器的最佳位置通常是薄组织耳或婴儿的薄组织手指或脚趾。

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