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1. 发明授权

US5536251A Thoracoscopic devices and methods for arresting the heart 失效
公开(公告)号：US5536251A
公开(公告)日：1996-07-16
申请号：US415273
申请日：1995-04-03
申请人： Philip C. Evard , Timothy R. MacHold , Hanson S. Gifford, III , Alex T. Roth , Wesley D. Sterman , Lawrence C. Siegel
发明人： Philip C. Evard , Timothy R. MacHold , Hanson S. Gifford, III , Alex T. Roth , Wesley D. Sterman , Lawrence C. Siegel
IPC分类号： A61B1/00 , A61B17/00 , A61B17/02 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/068 , A61B17/12 , A61B17/122 , A61B17/128 , A61B17/28 , A61B17/30 , A61B17/34 , A61B18/14 , A61B19/00 , A61F2/24 , A61F2/958 , A61M1/00 , A61M25/00 , A61M25/01 , A61M11/00
CPC分类号： A61B17/0218 , A61B17/00234 , A61B17/0469 , A61B17/06061 , A61B17/12013 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B18/1442 , A61B18/1492 , A61B90/50 , A61F2/2427 , A61M25/01 , A61M39/0247 , A61B17/0057 , A61B17/0467 , A61B17/064 , A61B17/068 , A61B17/29 , A61B17/2909 , A61B17/295 , A61B17/30 , A61B17/34 , A61B17/3403 , A61B2017/00243 , A61B2017/00247 , A61B2017/00353 , A61B2017/00544 , A61B2017/00637 , A61B2017/00663 , A61B2017/0243 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61B2017/2905 , A61B2017/2933 , A61B2017/2943 , A61B2017/2945 , A61B2017/2946 , A61B2017/306 , A61B2017/3405 , A61B2017/3427 , A61B2017/3445 , A61B2017/3492 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00291 , A61B2018/00363 , A61B2018/00392 , A61B2018/00577 , A61B2018/1432 , A61B2090/064 , A61M2025/0003 , A61M2025/0089 , A61M2025/028 , A61M2039/0279 , A61M2202/047 , A61M2205/3344 , A61M2205/3355 , A61M2205/366 , A61M2210/127 , A61M25/1011 , Y10S128/26
摘要： The invention provides devices and methods for thoracoscopically arresting the heart and establishing cardiopulmonary bypass, thus facilitating a variety of less-invasive surgical procedures on and within the heart and great vessels of the thorax. In one embodiment, the invention provides a thoracoscopic system for arresting a patient's heart including a clamp configured for introduction into the patient's thoracic cavity through a percutaneous intercostal penetration in the patient's chest. The clamp is positionable about the patient's ascending aorta between the coronary arteries and the brachiocephalic artery. The clamp is coupled to the distal end of an elongated handle means for manipulating the clamp from a location outside of the patient's thoracic cavity. A means for actuating the clamp is coupled to the proximal end of the handle means. When actuated, the clamp blocks blood flow through the ascending aorta. A delivery cannula may be used to deliver cardioplegic fluid into the ascending aorta upstream from the clamp to arrest cardiac function.

2. 发明授权

US5425705A Thoracoscopic devices and methods for arresting the heart 失效
标题翻译：胸腔镜装置和止血方法
公开(公告)号：US5425705A
公开(公告)日：1995-06-20
申请号：US173899
申请日：1993-12-27
申请人： Philip C. Evard , Timothy R. Machold , Hanson S. Gifford, III , Alex T. Roth , Wesley D. Sterman , Lawrence C. Siegel , Jeffry J. Grainger
发明人： Philip C. Evard , Timothy R. Machold , Hanson S. Gifford, III , Alex T. Roth , Wesley D. Sterman , Lawrence C. Siegel , Jeffry J. Grainger
IPC分类号： A61B1/00 , A61B17/00 , A61B17/02 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/068 , A61B17/12 , A61B17/122 , A61B17/128 , A61B17/28 , A61B17/30 , A61B17/34 , A61B18/14 , A61B19/00 , A61F2/24 , A61F2/958 , A61M1/00 , A61M25/00 , A61M25/01
CPC分类号： A61B17/0218 , A61B17/00234 , A61B17/0469 , A61B17/06061 , A61B17/12013 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B18/1442 , A61B18/1492 , A61B90/50 , A61F2/2427 , A61M25/01 , A61M39/0247 , A61B17/0057 , A61B17/0467 , A61B17/064 , A61B17/068 , A61B17/29 , A61B17/2909 , A61B17/295 , A61B17/30 , A61B17/34 , A61B17/3403 , A61B2017/00243 , A61B2017/00247 , A61B2017/00353 , A61B2017/00544 , A61B2017/00637 , A61B2017/00663 , A61B2017/0243 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61B2017/2905 , A61B2017/2933 , A61B2017/2943 , A61B2017/2945 , A61B2017/2946 , A61B2017/306 , A61B2017/3405 , A61B2017/3427 , A61B2017/3445 , A61B2017/3492 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00291 , A61B2018/00363 , A61B2018/00392 , A61B2018/00577 , A61B2018/1432 , A61B2090/064 , A61M2025/0003 , A61M2025/0089 , A61M2025/028 , A61M2039/0279 , A61M2202/047 , A61M2205/3344 , A61M2205/3355 , A61M2205/366 , A61M2210/127 , A61M25/1011 , Y10S128/26
摘要： The invention provides devices and methods for thoracoscopically arresting the heart and establishing cardiopulmonary bypass, thus facilitating a variety of less-invasive surgical procedures on and within the heart and great vessels of the thorax. In one embodiment, the invention provides a thoracoscopic system for arresting a patient's heart including a clamp configured for introduction into the patient's thoracic cavity through a percutaneous intercostal penetration in the patient's chest. The clamp is positionable about the patient's ascending aorta between the coronary arteries and the brachiocephalic artery. The clamp is coupled to the distal end of an elongated handle means for manipulating the clamp from a location outside of the patient's thoracic cavity. A means for actuating the clamp is coupled to the proximal end of the handle means. When actuated, the clamp blocks blood flow through the ascending aorta. A delivery cannula may be used to deliver cardioplegic fluid into the ascending aorta upstream from the clamp to arrest cardiac function.
摘要翻译：本发明提供了用于胸腔镜阻塞心脏并建立心肺旁路的装置和方法，从而促进在胸部和/或胸部的心脏和大血管内部和内部的多种较小侵入性的外科手术。在一个实施例中，本发明提供了一种用于阻止患者心脏的胸腔镜系统，包括构造成通过患者胸部经皮肋间穿透引入患者胸腔的夹具。夹具可以围绕冠状动脉和头臂动脉之间的患者升主动脉定位。夹具联接到细长手柄的远端，用于从患者胸腔外部的位置操纵夹具。用于致动夹具的装置联接到手柄装置的近端。当启动时，夹具阻止血流通过升主动脉。输送插管可用于将心脏停搏液输送到夹钳上游的升主动脉以阻止心脏功能。

3. 发明授权

US5792094A Method of delivering cardioplegic fluid to a patient's heart 失效
标题翻译：将心脏停跳液输送到患者心脏的方法
公开(公告)号：US5792094A
公开(公告)日：1998-08-11
申请号：US535676
申请日：1995-09-28
申请人： John H. Stevens , Wesley D. Sterman , Hanson S. Gifford, III , Philip C. Evard , Timothy R. Machold
发明人： John H. Stevens , Wesley D. Sterman , Hanson S. Gifford, III , Philip C. Evard , Timothy R. Machold
IPC分类号： A61B17/00 , A61B17/28 , A61B17/32 , A61F2/24 , A61F2/958 , A61M1/36 , A61M25/00 , A61M25/01 , A61M25/06 , A61M29/02 , A61M37/00
CPC分类号： A61F2/2427 , A61B17/29 , A61F2/2433 , A61M1/3653 , A61M1/3659 , A61M25/0041 , A61M25/0147 , A61M25/0152 , A61M25/0662 , A61M25/10 , A61B17/320016 , A61B2017/00243 , A61B2018/00232 , A61B2018/00261 , A61F2/2436 , A61M2025/0031 , A61M2025/0078 , A61M2025/015 , A61M2025/0161 , A61M2025/028 , A61M2025/1047 , A61M2025/1052 , A61M2025/1077 , A61M2025/1095 , A61M2205/11 , A61M2205/366 , A61M2210/125 , A61M2210/127 , A61M25/0032 , A61M25/0125 , A61M25/1002
摘要： A system for accessing a patient's cardiac anatomy which includes an endovascular aortic partitioning device that separates the coronary arteries and the heart from the rest of the patient's arterial system. The endovascular device for partitioning a patient's ascending aorta comprises a flexible shaft having a distal end, a proximal end, and a fist inner lumen therebetween with an opening at the distal end. The shaft may have a preshaped distal portion with a curvature generally corresponding to the curvature of the patient's aortic arch. An expandable means, e.g. a balloon, is disposed near the distal end of the shaft proximal to the opening in the first inner lumen for occluding the ascending aorta so as to block substantially all blood flow therethrough for a plurality of cardiac cycles, while the patient is supported by cardiopulmonary bypass. The endovascular aortic partitioning device may be coupled to an arterial bypass cannula for delivering oxygenated blood to the patient's arterial system. The heart muscle or myocardium is paralyzed by the retrograde delivery of a cardioplegic fluid to the myocardium through patient's coronary sinus and coronary veins, or by antegrade delivery of cardioplegic fluid through a lumen in the endovascular aortic partitioning device to infuse cardioplegic fluid into the coronary arteries. The pulmonary trunk may be vented by withdrawing liquid from the trunk through an inner lumen of an elongated catheter. The cardiac accessing system is particularly suitable for removing the aortic valve and replacing the removed valve with a prosthetic valve.
摘要翻译：一种用于访问患者心脏解剖结构的系统，其包括将冠状动脉和心脏与患者动脉系统的其余部分分离的血管内主动脉分配装置。用于分隔患者升主动脉的血管内装置包括具有远端，近端和其中的第一内腔的柔性轴，在其前端具有开口。轴可以具有预先形成的远端部分，其曲率通常对应于患者主动脉弓的曲率。可膨胀装置，例如靠近靠近第一内腔中的开口的轴的远端附近的气囊，用于闭塞升主动脉，以便阻止基本上所有的血液通过其进行多个心动周期，同时患者由体外循环。血管内主动脉分配装置可以联接到动脉旁路套管，用于将氧合血液输送到患者的动脉系统。通过患者的冠状窦和冠状静脉逆行递送心脏停搏液到心肌，或者通过血管内主动脉分配装置的内腔顺序递送心脏停跳液，将心肌或心肌瘫痪，将心脏停搏液注入冠状动脉。可以通过从细长的导管的内腔中抽出液体来排出肺动脉干。心脏存取系统特别适用于去除主动脉瓣并用假体瓣替换去除的瓣膜。

4. 发明授权

US5868702A System for cardiac procedures 失效
标题翻译：心脏手术系统
公开(公告)号：US5868702A
公开(公告)日：1999-02-09
申请号：US819455
申请日：1997-03-17
申请人： John H. Stevens , Wesley D. Sterman , Hanson S. Gifford, III , Timothy R. Machold
发明人： John H. Stevens , Wesley D. Sterman , Hanson S. Gifford, III , Timothy R. Machold
IPC分类号： A61B17/00 , A61B17/28 , A61B17/32 , A61F2/24 , A61F2/958 , A61M1/36 , A61M25/00 , A61M25/01 , A61M25/06 , A61M29/02 , A61M31/00
CPC分类号： A61F2/2427 , A61B17/29 , A61F2/2433 , A61M1/3653 , A61M1/3659 , A61M25/0041 , A61M25/0147 , A61M25/0152 , A61M25/0662 , A61M25/10 , A61B17/320016 , A61B2017/00243 , A61B2018/00232 , A61B2018/00261 , A61F2/2436 , A61M2025/0031 , A61M2025/0078 , A61M2025/015 , A61M2025/0161 , A61M2025/028 , A61M2025/1047 , A61M2025/1052 , A61M2025/1077 , A61M2025/1095 , A61M2205/11 , A61M2205/366 , A61M2210/125 , A61M2210/127 , A61M25/0032 , A61M25/0125 , A61M25/1002
摘要： A system for accessing a patient's cardiac anatomy which includes an endovascular aortic partitioning device that separates the coronary arteries and the heart from the rest of the patient's arterial system. The endovascular device for partitioning a patient's ascending aorta comprises a flexible shaft having a distal end, a proximal end, and a first inner lumen therebetween with an opening at the distal end. The shaft may have a preshaped distal portion with a curvature generally corresponding to the curvature of the patient's aortic arch. An expandable means, e.g., a balloon, is disposed near the distal end of the shaft proximal to the opening in the first inner lumen for occluding the ascending aorta so as to block substantially all blood flow therethrough for a plurality of cardiac cycles, while the patient is supported by cardiopulmonary bypass. The endovascular aortic partitioning device may be coupled to an arterial bypass cannula for delivering oxygenated blood to the patient's arterial system. The heart muscle or myocardium is paralyzed by the retrograde delivery of a cardioplegic fluid to the myocardium through patient's coronary sinus and coronary veins, or by antegrade delivery of cardioplegic fluid through a lumen in the endovascular aortic partitioning device to infuse cardioplegic fluid into the coronary arteries. The pulmonary trunk may be vented by withdrawing liquid from the trunk through an inner lumen of an elongated catheter. The cardiac accessing system is particularly suitable for removing the aortic valve and replacing the removed valve with a prosthetic valve.
摘要翻译：一种用于访问患者心脏解剖结构的系统，其包括将冠状动脉和心脏与患者动脉系统的其余部分分离的血管内主动脉分配装置。用于分隔患者升主动脉的血管内装置包括具有远端，近端和其间的第一内腔的柔性轴，在远端具有开口。轴可以具有预先形成的远端部分，其曲率通常对应于患者主动脉弓的曲率。一个可膨胀的装置，例如气球，靠近靠近第一内腔内的开口的轴的远端设置，用于闭塞上升主动脉，从而阻止基本上所有的血流通过其中进行多个心动周期，而患者由体外循环支持。血管内主动脉分配装置可以联接到动脉旁路套管，用于将氧合血液输送到患者的动脉系统。通过患者的冠状窦和冠状静脉逆行递送心脏停搏液到心肌，或者通过血管内主动脉分配装置的内腔顺序递送心脏停跳液，将心肌或心肌瘫痪，将心脏停搏液注入冠状动脉。可以通过从细长的导管的内腔中抽出液体来排出肺动脉干。心脏存取系统特别适用于去除主动脉瓣并用假体瓣替换去除的瓣膜。

5. 发明授权

US5702368A System for cardiac procedures 失效
标题翻译：心脏手术系统
公开(公告)号：US5702368A
公开(公告)日：1997-12-30
申请号：US453333
申请日：1995-05-30
申请人： John H. Stevens , Wesley D. Sterman , Hanson S. Gifford, III , Timothy R. Machold
发明人： John H. Stevens , Wesley D. Sterman , Hanson S. Gifford, III , Timothy R. Machold
IPC分类号： A61B17/00 , A61B17/28 , A61B17/32 , A61F2/24 , A61F2/958 , A61M1/36 , A61M25/00 , A61M25/01 , A61M25/06 , A61M29/02 , A61M5/00 , A61M37/00
CPC分类号： A61F2/2427 , A61B17/29 , A61F2/2433 , A61M1/3653 , A61M1/3659 , A61M25/0041 , A61M25/0147 , A61M25/0152 , A61M25/0662 , A61M25/10 , A61B17/320016 , A61B2017/00243 , A61B2018/00232 , A61B2018/00261 , A61F2/2436 , A61M2025/0031 , A61M2025/0078 , A61M2025/015 , A61M2025/0161 , A61M2025/028 , A61M2025/1047 , A61M2025/1052 , A61M2025/1077 , A61M2025/1095 , A61M2205/11 , A61M2205/366 , A61M2210/125 , A61M2210/127 , A61M25/0032 , A61M25/0125 , A61M25/1002
摘要： A system for accessing a patient's cardiac anatomy which includes an endovascular aortic partitioning device that separates the coronary arteries and the heart from the rest of the patient's arterial system. The endovascular device for partitioning a patient's ascending aorta comprises a flexible shaft having a distal end, a proximal end, and a first inner lumen therebetween with an opening at the distal end. The shaft may have a preshaped distal portion with a curvature generally corresponding to the curvature of the patient's aortic arch. An expandable means, e.g. a balloon, is disposed near the distal end of the shaft proximal to the opening in the first inner lumen for occluding the ascending aorta so as to block substantially all blood flow therethrough for a plurality of cardiac cycles, while the patient is supported by cardiopulmonary bypass. The endovascular aortic partitioning device may be coupled to an arterial bypass cannula for delivering oxygenated blood to the patient's arterial system. The heart muscle or myocardium is paralyzed by the retrograde delivery of a cardioplegic fluid to the myocardium through patient's coronary sinus and coronary veins, or by antegrade delivery of cardioplegic fluid through a lumen in the endovascular aortic partitioning device to infuse cardioplegic fluid into the coronary arteries. The pulmonary trunk may be vented by withdrawing liquid from the trunk through an inner lumen of an elongated catheter. The cardiac accessing system is particularly suitable for removing the aortic valve and replacing the removed valve with a prosthetic valve.
摘要翻译：一种用于访问患者心脏解剖结构的系统，其包括将冠状动脉和心脏与患者动脉系统的其余部分分离的血管内主动脉分配装置。用于分隔患者升主动脉的血管内装置包括具有远端，近端和其间的第一内腔的柔性轴，在远端具有开口。轴可以具有预先形成的远端部分，其曲率通常对应于患者主动脉弓的曲率。可膨胀装置，例如靠近靠近第一内腔中的开口的轴的远端附近的气囊，用于闭塞升主动脉，以便阻止基本上所有的血液通过其进行多个心动周期，同时患者由体外循环。血管内主动脉分配装置可以联接到动脉旁路套管，用于将氧合血液输送到患者的动脉系统。通过患者的冠状窦和冠状静脉逆行递送心脏停搏液到心肌，或者通过血管内主动脉分配装置的内腔顺序递送心脏停跳液，将心肌或心肌瘫痪，将心脏停搏液注入冠状动脉。可以通过从细长的导管的内腔中抽出液体来排出肺动脉干。心脏存取系统特别适用于去除主动脉瓣并用假体瓣替换去除的瓣膜。

6. 发明授权

US06866650B2 System for cardiac procedures 失效
标题翻译：心脏手术系统
公开(公告)号：US06866650B2
公开(公告)日：2005-03-15
申请号：US09776336
申请日：2001-02-02
申请人： John H. Stevens , Wesley D. Sterman , Hanson S. Gifford, III , Timothy R. Machold
发明人： John H. Stevens , Wesley D. Sterman , Hanson S. Gifford, III , Timothy R. Machold
IPC分类号： A61B17/00 , A61F2/24 , A61F2/958 , A61M1/36 , A61M25/00 , A61M25/01 , A61M25/06 , A61M29/02 , A61M29/00
CPC分类号： A61M25/0147 , A61B2017/00243 , A61B2018/00232 , A61B2018/00261 , A61F2/2427 , A61M1/3653 , A61M1/3659 , A61M25/0032 , A61M25/0041 , A61M25/0125 , A61M25/0152 , A61M25/0662 , A61M25/10 , A61M25/1002 , A61M2025/0031 , A61M2025/0078 , A61M2025/015 , A61M2025/0161 , A61M2025/028 , A61M2025/1047 , A61M2025/1052 , A61M2025/1077 , A61M2025/1095 , A61M2202/047 , A61M2205/11 , A61M2205/366 , A61M2210/125 , A61M2210/127
摘要： A system for accessing a patient's cardiac anatomy which includes an endovascular aortic partitioning device that separates the coronary arteries and the heart from the rest of the patient's arterial system. The endovascular device for partitioning a patient's ascending aorta comprises a flexible shaft having a distal end, a proximal end, and a first inner lumen therebetween with an opening at the distal end. The shaft may have a preshaped distal portion with a curvature generally corresponding to the curvature of the patient's aortic arch. An expandable means, e.g. a balloon, is disposed near the distal end of the shaft proximal to the opening in the first inner lumen for occluding the ascending aorta so as to block substantially all blood flow therethrough for a plurality of cardiac cycles, while the patient is supported by cardiopulmonary bypass. The endovascular aortic partitioning device may be coupled to an arterial bypass cannula for delivering oxygenated blood to the patient's arterial system. The heart muscle or myocardium is paralyzed by the retrograde delivery of a cardioplegic fluid to the myocardium through patient's coronary sinus and coronary veins, or by antegrade delivery of cardioplegic fluid through a lumen in the endovascular aortic partitioning device to infuse cardioplegic fluid into the coronary arteries. The pulmonary trunk may be vented by withdrawing liquid from the trunk through an inner lumen of an elongated catheter. The cardiac accessing system is particularly suitable for removing the aortic valve and replacing the removed valve with a prosthetic valve.
摘要翻译：一种用于访问患者心脏解剖结构的系统，其包括将冠状动脉和心脏与患者动脉系统的其余部分分离的血管内主动脉分配装置。用于分隔患者升主动脉的血管内装置包括具有远端，近端和其间的第一内腔的柔性轴，在远端具有开口。轴可以具有预先形成的远端部分，其曲率通常对应于患者主动脉弓的曲率。可膨胀装置，例如靠近靠近第一内腔中的开口的轴的远端附近的气囊，用于闭塞升主动脉，以便阻止基本上所有的血液通过其进行多个心动周期，同时患者由体外循环。血管内主动脉分配装置可以联接到动脉旁路套管，用于将氧合血液输送到患者的动脉系统。通过患者的冠状窦和冠状静脉逆行递送心脏停搏液到心肌，或者通过血管内主动脉分配装置的内腔顺序递送心脏停跳液，将心肌或心肌瘫痪，将心脏停搏液注入冠状动脉。可以通过从细长的导管的内腔中抽出液体来排出肺动脉干。心脏存取系统特别适用于去除主动脉瓣并用假体瓣替换去除的瓣膜。

7. 发明授权

US06699231B1 Methods and apparatus for perfusion of isolated tissue structure 有权
标题翻译：分离组织结构灌注的方法和装置
公开(公告)号：US06699231B1
公开(公告)日：2004-03-02
申请号：US09223229
申请日：1998-12-30
申请人： Wesley D. Sterman , John H. Stevens , Hanson S. Gifford, III , Lawrence C. Siegel , Joe B. Putnam
发明人： Wesley D. Sterman , John H. Stevens , Hanson S. Gifford, III , Lawrence C. Siegel , Joe B. Putnam
IPC分类号： A61M3100
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B2017/12127 , A61M25/1011 , A61M2025/1052
摘要： Organs and other tissue structures are isolated and perfused with a therapeutic agent. Isolation is effected by endovascularly positioning catheters having occlusion balloons within the arteries or other blood vessels which supply blood to the organ. Similarly, blood flow from the organ back to the patient's circulatory system is blocked by endovascularly positioning one or more catheters carrying occlusion members within the veins or other blood vessels leading from the organ. The therapeutic agent may then be perfused through the organ in either an antegrade or retrograde fashion using the endovascularly positioned catheters while maintaining isolation.
摘要翻译：器官和其他组织结构被分离并用治疗剂灌注。通过血管内定位具有在动脉或其他血管中向患者提供血液的阻塞球囊的导管进行分离。类似地，从器官返回到患者的循环系统的血液流动通过血管内定位将携带闭塞构件的一个或多个导管从器官导向的静脉或其他血管内被阻断。然后治疗剂可以使用血管内定位的导管在顺行或逆行方式中通过器官灌注，同时保持隔离。

8. 发明授权

US06283127B1 Devices and methods for intracardiac procedures 有权
标题翻译：用于心内手术的装置和方法
公开(公告)号：US06283127B1
公开(公告)日：2001-09-04
申请号：US09161190
申请日：1998-09-25
申请人： Wesley D. Sterman , Michi E. Garrison , Hanson S. Gifford, III , John L. Stevens
发明人： Wesley D. Sterman , Michi E. Garrison , Hanson S. Gifford, III , John L. Stevens
IPC分类号： A61B1700
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/0218 , A61B17/0467 , A61B17/0469 , A61B17/06061 , A61B17/064 , A61B17/068 , A61B17/12013 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B17/29 , A61B17/2909 , A61B17/30 , A61B17/3403 , A61B18/1442 , A61B18/1492 , A61B90/50 , A61B2017/00243 , A61B2017/00247 , A61B2017/00637 , A61B2017/00663 , A61B2017/0243 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61B2017/2943 , A61B2017/306 , A61B2017/3405 , A61B2017/3427 , A61B2017/3492 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00291 , A61B2018/00363 , A61B2018/00392 , A61B2018/00577 , A61B2090/064 , A61F2/2427 , A61F2/2496 , A61M1/3664 , A61M25/0023 , A61M25/0032 , A61M25/1011 , A61M39/0247 , A61M2025/0003 , A61M2025/028 , A61M2025/1052 , A61M2039/027 , A61M2039/0279 , A61M2202/047 , A61M2205/3344 , A61M2205/3355 , A61M2205/366 , A61M2210/127 , A61M2230/005
摘要： The invention provides devices and methods for performing less-invasive surgical procedures within an organ or vessel. In an exemplary embodiment, the invention provides a method of closed-chest surgical intervention within an internal cavity of a patient's heart or great vessel. According to the method, the patient's heart is arrested and cardiopulmonary bypass is established. A scope extending through a percutaneous intercostal penetration in the patient's chest is used to view an internal portion of the patient's chest. An internal penetration is formed in a wall of the heart or great vessel using cutting means introduced through a percutaneous penetration in an intercostal space in the patient's chest. An interventional tool is then introduced, usually through a cannula positioned in a percutaneous intercostal penetration. The interventional tool is inserted through the internal penetration in the heart or great vessel to perform a surgical procedure within the internal cavity under visualization by means of the scope. In a preferred embodiment, a cutting tool is introduced into the patient's left atrium from a right portion of the patient's chest to remove the patient's mitral valve. A replacement valve is then introduced through an intercostal space in the right portion of the chest and through the internal penetration in the heart, and the replacement valve is attached in the mitral valve position.
摘要翻译：本发明提供了用于在器官或血管内执行较少侵入性外科手术的装置和方法。在一个示例性实施例中，本发明提供了一种在患者心脏或大血管的内腔内进行闭胸手术干预的方法。根据该方法，患者的心脏被停止并建立了体外循环。使用延伸穿过患者胸部经皮肋间穿透的范围来观察患者胸部的内部部分。使用通过在患者胸部的肋间空间经皮渗透引入的切割装置在心脏或大容器的壁上形成内部穿透。然后引入介入工具，通常通过定位在经皮肋间穿透中的套管。介入工具通过心脏或大容器中的内部穿透插入，通过范围在可视化的内部空腔内执行外科手术。在优选实施例中，切割工具从患者胸部的右侧部分引入患者的左心房以移除患者的二尖瓣。然后将置换瓣膜通过胸部右侧部分的肋间空间并通过心脏内部穿透引入，置换瓣膜连接于二尖瓣位置。

9. 发明授权

US07967833B2 Devices and methods for intracardiac procedures 有权
标题翻译：用于心内手术的装置和方法
公开(公告)号：US07967833B2
公开(公告)日：2011-06-28
申请号：US10941661
申请日：2004-09-15
申请人： Wesley D. Sterman , Michi E. Garrison , Hanson S. Gifford, III , John H. Stevens , William S. Peters
发明人： Wesley D. Sterman , Michi E. Garrison , Hanson S. Gifford, III , John H. Stevens , William S. Peters
IPC分类号： A61B17/00
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/0218 , A61B17/0467 , A61B17/0469 , A61B17/06061 , A61B17/064 , A61B17/068 , A61B17/12013 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B17/29 , A61B17/2909 , A61B17/30 , A61B17/3403 , A61B18/1442 , A61B18/1492 , A61B90/50 , A61B2017/00243 , A61B2017/00247 , A61B2017/00637 , A61B2017/00663 , A61B2017/0243 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61B2017/2943 , A61B2017/306 , A61B2017/3405 , A61B2017/3427 , A61B2017/3492 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00291 , A61B2018/00363 , A61B2018/00392 , A61B2018/00577 , A61B2090/064 , A61F2/2427 , A61F2/2496 , A61M1/3664 , A61M25/0023 , A61M25/0032 , A61M25/1011 , A61M39/0247 , A61M2025/0003 , A61M2025/028 , A61M2025/1052 , A61M2039/027 , A61M2039/0279 , A61M2202/047 , A61M2205/3344 , A61M2205/3355 , A61M2205/366 , A61M2210/127 , A61M2230/005
摘要： The invention provides devices and methods for performing closed-chest surgical intervention within an internal cavity of a patient's heart or great vessel. A scope extending through a percutaneous intercostal penetration in the patient's chest is used to view an internal portion of the patient's chest. An internal penetration is formed in a wall of the heart or great vessel using cutting means introduced through a percutaneous penetration in an intercostal space in the patient's chest. An interventional tool is inserted through the internal penetration to perform a surgical procedure under visualization using the scope. A cutting tool is introduced into the patient's left atrium from a right portion of the patient's chest to remove the patient's mitral valve. A replacement valve is then introduced through an intercostal space in the right portion of the chest and through the internal penetration in the heart, and the replacement valve is attached in the mitral valve position.
摘要翻译：本发明提供了用于在患者的心脏或大容器的内腔内执行闭胸手术干预的装置和方法。使用延伸穿过患者胸部经皮肋间穿透的范围来观察患者胸部的内部部分。使用通过在患者胸部的肋间空间经皮渗透引入的切割装置在心脏或大容器的壁上形成内部穿透。通过内部穿透插入介入工具，以使用范围进行可视化的外科手术。从患者胸部的右侧部分向患者的左心房引入切割工具以移除患者的二尖瓣。然后将置换瓣膜通过胸部右侧部分的肋间空间并通过心脏内部穿透引入，置换瓣膜连接于二尖瓣位置。

10. 发明授权

US06368340B2 Clamp assembly and method of use 失效
标题翻译：夹具组合及使用方法
公开(公告)号：US06368340B2
公开(公告)日：2002-04-09
申请号：US09225258
申请日：1999-01-04
申请人： William W. Malecki , Wesley D. Sterman , Hanson S. Gifford, III , Scott H. Miller
发明人： William W. Malecki , Wesley D. Sterman , Hanson S. Gifford, III , Scott H. Miller
IPC分类号： A61B1728
CPC分类号： A61B17/29 , A61B17/00234 , A61B17/064 , A61B17/12013 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B17/2909 , A61B17/295 , A61B17/34 , A61B2017/00243 , A61B2017/00353 , A61B2017/00544 , A61B2017/2905 , A61B2017/2933 , A61B2017/2943 , A61B2017/2945 , A61B2017/2946 , A61B2017/3445 , A61B2018/1432 , A61M2205/3344 , A61M2205/3355
摘要： A clamp for clamping a body structure in a patient. The clamp includes a flexible cable housed within a sheath. The cable and sheath extend between a clamp and a handle. The cable actuator. The cable extends through a sheath which is anchored at the clamp and the actuator for actuating jaws from a proximal end of the clamp. A malleable positioner is provided for positioning the clamp about the body structure.
摘要翻译：用于夹持患者体内结构的夹具。夹具包括容纳在护套内的柔性电缆。电缆和护套在夹具和手柄之间延伸。电缆执行器。电缆延伸穿过固定在夹具上的护套和用于从夹具的近端致动爪的致动器。提供可伸缩的定位器用于将夹具围绕身体结构定位。

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