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1. 发明申请

US20080145429A1 Dosage Form Containing Oxycodone and Naloxone 审中-公开
标题翻译：含有羟考酮和纳洛酮的剂型
公开(公告)号：US20080145429A1
公开(公告)日：2008-06-19
申请号：US11885288
申请日：2006-02-28
申请人： Petra Leyendecker , Michael Hopp , Kevin Smith
发明人： Petra Leyendecker , Michael Hopp , Kevin Smith
IPC分类号： A61K9/00 , A61K31/4355 , A61P43/00 , A61P25/30
CPC分类号： A61K31/485 , A61K9/28 , A61K2300/00
摘要： The present invention concerns a dosage form comprising oxycodone and naloxone which is characterized by specific in vivo parameters such as tmax, Cmax, AUCt value, mean bowel function score and/or duration of analgesic efficacy.
摘要翻译：本发明涉及包含羟考酮和纳洛酮的剂型，其特征在于特定的体内参数，例如最大，最大，AUCt值，平均肠功能评分和/ 或止痛效力持续时间。

2. 发明申请

US20110172259A1 DOSAGE FORM CONTAINING OXYCODONE AND NALOXONE 审中-公开
标题翻译：含有氧化剂和纳洛酮的剂型
公开(公告)号：US20110172259A1
公开(公告)日：2011-07-14
申请号：US12945164
申请日：2010-11-12
申请人： Petra Leyendecker , Michael Hopp , Kevin Smith
发明人： Petra Leyendecker , Michael Hopp , Kevin Smith
IPC分类号： A61K31/485 , A61P25/04
CPC分类号： A61K31/485 , A61K9/28 , A61K2300/00
摘要： The present invention concerns a dosage form comprising oxycodone and naloxone which is characterized by specific in vivo parameters such as tmax, Cmax, AUCt value, mean bowel function score and/or duration of analgesic efficacy.
摘要翻译：本发明涉及包含羟考酮和纳洛酮的剂型，其特征在于特定的体内参数，例如tmax，Cmax，AUCt值，平均肠功能评分和/或止痛效力持续时间。

3. 发明申请

US20110177133A1 USE OF OPIOID ANTAGONISTS FOR TREATING URINARY RETENTION 审中-公开
标题翻译：使用阿片类拮抗剂治疗尿毒症
公开(公告)号：US20110177133A1
公开(公告)日：2011-07-21
申请号：US13002568
申请日：2009-07-07
申请人： Michael Hopp , Petra Leyendecker
发明人： Michael Hopp , Petra Leyendecker
IPC分类号： A61K31/485 , C07D489/08 , A61K9/00 , A61P13/00
CPC分类号： A61K9/14 , A61K31/00 , A61K31/485 , A61K2300/00
摘要： The invention pertains to the use of opioid antagonists for the treatment of urinary retention.
摘要翻译：本发明涉及阿片样物质拮抗剂用于治疗尿潴留的用途。

4. 发明授权

US10258235B2 Method and device for the assessment of bowel function 有权
公开(公告)号：US10258235B2
公开(公告)日：2019-04-16
申请号：US11885285
申请日：2006-02-28
申请人： Petra Leyendecker , Michael Hopp , Axel Drews
发明人： Petra Leyendecker , Michael Hopp , Axel Drews
IPC分类号： A61B5/00 , G16H10/20 , G16H40/63
摘要： The present invention provides a method for assessing bowel function in a patient, comprising providing the patient with a numeric analog scale for at least one parameter which is a measure of bowel function; causing the patient to indicate on the numeric analog scale the amount and/or intensity of the parameter being experienced; and observing the amount and/or intensity of the at least one parameter indicated on the numeric analog scale in order to assess bowel function. Further, the present invention provides a device for assessing bowel function in a patient, the device comprising a display unit for providing a numeric analog scale for at least one parameter which is associated with bowel function of a patient; a receiving unit adapted to receive an amount and/or intensity of the at least one parameter indicated by the patient on the numeric analog scale; and an interface unit adapted to provide the amount and/or intensity of the at least one parameter indicated on the numeric analog scale in order to assess bowel function.

5. 发明申请

US20080167533A1 Method and Device for the Assessment of Bowel Function 审中-公开
标题翻译：肠功能评估方法与装置
公开(公告)号：US20080167533A1
公开(公告)日：2008-07-10
申请号：US11885285
申请日：2006-02-28
申请人： Petra Leyendecker , Michael Hopp , Axel Drews
发明人： Petra Leyendecker , Michael Hopp , Axel Drews
IPC分类号： A61B5/00
CPC分类号： A61B5/00 , A61B5/4255 , A61B5/4824 , G06F19/00 , G16H10/20 , G16H40/63
摘要： The present invention provides a method for assessing bowel function in a patient, comprising providing the patient with a numeric analog scale for at least one parameter which is a measure of bowel function; causing the patient to indicate on the numeric analog scale the amount and/or intensity of the parameter being experienced; and observing the amount and/or intensity of the at least one parameter indicated on the numeric analog scale in order to assess bowel function. Further, the present invention provides a device for assessing bowel function in a patient, the device comprising a display unit for providing a numeric analog scale for at least one parameter which is associated with bowel function of a patient; a receiving unit adapted to receive an amount and/or intensity of the at least one parameter indicated by the patient on the numeric analog scale; and an interface unit adapted to provide the amount and/or intensity of the at least one parameter indicated on the numeric analog scale in order to assess bowel function.
摘要翻译：本发明提供了一种用于评估患者肠功能的方法，包括向所述患者提供用于至少一个作为肠功能测量的参数的数字模拟量表; 使患者在数字模拟量表上指示经历的参数的量和/或强度; 并且观察数字模拟量表上指示的至少一个参数的量和/或强度以便评估肠功能。此外，本发明提供了一种用于评估患者肠功能的装置，该装置包括：显示单元，用于为与患者的肠功能相关联的至少一个参数提供数字模拟量表; 接收单元，适于接收由数字模拟量表上的患者指示的至少一个参数的量和/或强度; 以及接口单元，其适于提供数字模拟量表上指示的至少一个参数的量和/或强度，以便评估肠功能。

6. 发明授权

US08518925B2 Opioids for the treatment of the chronic obstructive pulmonary disease (COPD) 有权
标题翻译：用于治疗慢性阻塞性肺疾病（COPD）的阿片样物质
公开(公告)号：US08518925B2
公开(公告)日：2013-08-27
申请号：US11570197
申请日：2005-06-08
申请人： Wolfgang Fleischer , Karen Reimer , Petra Leyendecker
发明人： Wolfgang Fleischer , Karen Reimer , Petra Leyendecker
IPC分类号： A01N43/00 , A01N43/42 , A61K31/33 , A61K31/44
CPC分类号： A61K31/485 , A61K2300/00
摘要： The present invention relates to an opioid controlled release oral dosage form comprising at least one opioid for the manufacture of a medicament to treat patients with Chronic Obstructive Pulmonary Disease (COPD).
摘要翻译：本发明涉及阿片样物质控释口服剂型，其包含至少一种用于制备治疗慢性阻塞性肺疾病（COPD）患者的药物的阿片样物质。

7. 发明申请

US20070185146A1 Opioids for the treatment of the chronic obstructive pulmonary disease (copd) 有权
标题翻译：阿片类药物治疗慢性阻塞性肺疾病（copd）
公开(公告)号：US20070185146A1
公开(公告)日：2007-08-09
申请号：US11570197
申请日：2005-06-08
申请人： Wolfgang Fleischer , Karen Reimer , Petra Leyendecker
发明人： Wolfgang Fleischer , Karen Reimer , Petra Leyendecker
IPC分类号： A61K31/44
CPC分类号： A61K31/485 , A61K2300/00
摘要： The present invention relates to an opioid controlled release oral dosage form comprising at least one opioid for the manufacture of a medicament to treat patients with Chronic Obstructive Pulmonary Disease (COPD).
摘要翻译：本发明涉及阿片样物质控释口服剂型，其包含至少一种用于制备治疗慢性阻塞性肺疾病（COPD）患者的药物的阿片样物质。

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