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1. 发明授权

US06214363B1 Liquid antimicrobial cleansing compositions which provide residual benefit versus gram negative bacteria 失效
标题翻译：提供残留益处与革兰氏阴性细菌的液体抗菌清洁组合物
公开(公告)号：US06214363B1
公开(公告)日：2001-04-10
申请号：US08969077
申请日：1997-11-12
申请人： Peter William Beerse , Jeffrey Michael Morgan , Kathleen Grieshop Baier , Robert Gregory Bartolo , Theresa Anne Bakken , Mary Elizabeth Carethers , Mark Richard Sine , Mannie Lee Clapp , Raphael Warren
发明人： Peter William Beerse , Jeffrey Michael Morgan , Kathleen Grieshop Baier , Robert Gregory Bartolo , Theresa Anne Bakken , Mary Elizabeth Carethers , Mark Richard Sine , Mannie Lee Clapp , Raphael Warren
IPC分类号： A01N2534
CPC分类号： A61Q17/005 , A61K8/347 , A61K8/442 , A61K8/463 , A61Q19/00
摘要： The present invention relates to a rinse-off antimicrobial cleansing composition comprising from about 0.001% to about 5% of an antimicrobial active, from about 1% to about 80% of an anionic surfactant, from about 0.1% to about 12% of a proton donating agent; from about 0.1% to about 30% of a deposition aid; and from about 3% to about 98.8% of water, wherein the composition is adjusted to a pH of from about 3.0 to about 6.0, wherein the rinse-off antimicrobial cleansing composition has a Gram Negative Residual Effectiveness Index of greater than about 0.3, and wherein the rinse-off antimicrobial cleansing composition has a Mildness Index of greater than 0.3. The invention also encompasses methods for cleansing skin and providing residual effectiveness versus Gram negative bacteria using these products.
摘要翻译：本发明涉及一种漂洗抗微生物清洁组合物，其包含约0.001％至约5％的抗微生物活性剂，约1％至约80％的阴离子表面活性剂，约0.1％至约12％的质子捐赠代理人约0.1％至约30％的沉积助剂; 和约3％至约98.8％的水，其中将组合物调节至约3.0至约6.0的pH，其中冲洗抗微生物清洁组合物具有大于约0.3的革兰氏阴性残留有效性指数，以及其中所述洗涤抗微生物清洁组合物的温和指数大于0.3。本发明还包括使用这些产品的用于清洁皮肤并提供与革兰氏阴性细菌的残留效力的方法。

2. 发明授权

US06190674B1 Liquid antimicrobial cleansing compositions 失效
标题翻译：液体抗菌清洁组合物
公开(公告)号：US06190674B1
公开(公告)日：2001-02-20
申请号：US08869117
申请日：1997-06-04
申请人： Peter William Beerse , Jeffrey Michael Morgan , Kathleen Grieshop Baier , Robert Gregory Bartolo , Theresa Anne Bakken , Mark Richard Sine
发明人： Peter William Beerse , Jeffrey Michael Morgan , Kathleen Grieshop Baier , Robert Gregory Bartolo , Theresa Anne Bakken , Mark Richard Sine
IPC分类号： A61K600
CPC分类号： A61K8/466 , A61K8/347 , A61K8/368 , A61K8/463 , A61K2800/596 , A61Q17/005 , A61Q19/10 , Y10S514/975
摘要： The present invention relates to a rinse-off antimicrobial cleansing composition comprising from about 0.1% to about 5% of an antimicrobial active, from about 8% to about 18% of an anionic surfactant, from about 2% to about 12% of a proton donating agent; from about 1% to about 30% of a lipophilic skin moisturizing agent; from about 0.1% to about 4% of a stabilizer; and from about 35% to about 88.8% of water. At least about 67% of the anionic surfactant comprises a mixture of Class A and Class C surfactant. The weight ratio of Class A surfactant to Class C surfactant ranges from about 5:1 to about 1:2. The composition is adjusted to a pH of from about 3.5 to about 4.5.
摘要翻译：本发明涉及一种漂洗抗微生物清洁组合物，其包含约0.1％至约5％的抗微生物活性剂，约8％至约18％的阴离子表面活性剂，约2％至约12％的质子捐赠代理人约1％至约30％的亲脂性皮肤保湿剂; 约0.1％至约4％的稳定剂; 和约35％至约88.8％的水。至少约67％的阴离子表面活性剂包括A类和C类表面活性剂的混合物。 A类表面活性剂与C类表面活性剂的重量比为约5:1至约1:2。将组合物调节至约3.5至约4.5的pH。

3. 发明授权

US06451333B1 Mild, rinse-off antimicrobial liquid cleansing compositions 有权
标题翻译：温和的，冲洗的抗菌液体清洁组合物
公开(公告)号：US06451333B1
公开(公告)日：2002-09-17
申请号：US09323419
申请日：1999-06-01
申请人： Peter William Beerse , Jeffrey Michael Morgan , Kathleen Grieshop Baier , Robert Gregory Bartolo , Theresa Anne Bakken Schuette
发明人： Peter William Beerse , Jeffrey Michael Morgan , Kathleen Grieshop Baier , Robert Gregory Bartolo , Theresa Anne Bakken Schuette
IPC分类号： A01N2500
CPC分类号： A61Q19/00 , A61K8/347 , A61K8/365 , A61K8/368 , A61K8/463 , A61K8/466 , A61K8/4933 , A61Q5/02 , A61Q17/005 , A61Q19/10 , C11D1/37 , C11D3/042 , C11D3/2034 , C11D3/2075 , C11D3/3773 , C11D3/48 , Y10S514/975
摘要： The present invention relates to a rinse-off antimicrobial cleansing composition comprising from about 0.1% to about 5.0%, by weight of the cleansing composition, of an antimicrobial active; from about 9% to about 14%, by weight of the cleansing composition, of an anionic surfactant, wherein at least about 67% of the anionic surfactant is selected from the group consisting of Class A surfactants, Class C surfactants, and mixtures thereof, wherein the ratio of Class A surfactant to Class C is from about 4:1 to about 1.5:1, and wherein the total anionic surfactant comprises less than about 50% of the ammonium counter cation salt; from about 4% to about 8%, by weight of the cleansing composition, of a proton donating agent having a Biological Activity Index, Z, of greater than about 0.75 and wherein the proton donating agent is such that the composition is essentially free of C4-C20 alkyl fatty acid; a mildness enhancing agent selected from the group consisting of from about 20% to about 70%, by weight of the anionic surfactant, of a mildness enhancing cosurfactant; form about 0.1% to about 1.0%, by weight of the cleansing composition, of a mildness enhancing polymer; and mixtures thereof; and from about 35% to about 93.9%, by weight of the cleansing composition, of water; wherein the composition is adjusted to a pH of greater than about 3.5 and less than about 4.5. The invention also encompasses methods for cleansing, removing germs and decreasing the spread of transient Gram negative and Gram positive bacteria using the rinse-off antimicrobial cleansing compositions described herein.
摘要翻译：本发明涉及一种洗涤抗微生物清洁组合物，其包含按重量计约0.1％至约5.0％的清洁组合物的抗微生物活性物质; 约9％至约14％的所述清洁组合物的阴离子表面活性剂，其中至少约67％的阴离子表面活性剂选自A类表面活性剂，C类表面活性剂及其混合物，其中A类表面活性剂与C类的比例为约4:1至约1.5:1，并且其中总阴离子表面活性剂包含小于约50％的铵抗衡阳离子盐; 约4％至约8％的清洁组合物，具有大于约0.75的生物活性指数Z的质子供体，其中质子供体剂使得组合物基本上不含C4 -C 20烷基脂肪酸; 选自按重量计约20％至约70％的阴离子表面活性剂的温和增强助剂，具有温和增强助表面活性剂; 形成约0.1重量％至约1.0重量％的清洁组合物;增温聚合物; 及其混合物; 和约35％至约93.9％（重量）的清洁组合物; 其中将组合物调节至大于约3.5且小于约4.5的pH。本发明还包括使用本文所述的冲洗性抗微生物清洁组合物清洁，去除细菌并减少瞬时革兰氏阴性和革兰氏阳性细菌的扩散的方法。

4. 发明授权

US6113933A Mild, rinse-off antimicrobial liquid cleansing compositions containing acidic surfactants 失效
标题翻译：含有酸性表面活性剂的轻度，冲洗性抗微生物液体清洁组合物
公开(公告)号：US6113933A
公开(公告)日：2000-09-05
申请号：US323513
申请日：1999-06-01
申请人： Peter William Beerse , Jeffrey Michael Morgan , Kathleen Grieshop Baier , Robert Gregory Bartolo , Theresa Anne Bakken Schuette
发明人： Peter William Beerse , Jeffrey Michael Morgan , Kathleen Grieshop Baier , Robert Gregory Bartolo , Theresa Anne Bakken Schuette
IPC分类号： A61K8/00 , A01N25/30 , A01N25/34 , A61K20060101 , A61K8/49 , A61K8/58 , A61Q5/02 , A61Q19/10 , C11D20060101 , C11D1/02 , C11D3/00 , C11D3/48 , A61K7/40 , A61K7/50
CPC分类号： A61Q17/005 , A61K8/347 , A61K8/442 , A61K8/463 , A61K8/466 , A61Q19/10 , A61K2800/596 , A61Q5/02 , Y10S514/975
摘要： The present invention relates to a rinse-off antimicrobial cleansing composition comprising from about 0.1% to about 5.0%, by weight of the cleansing composition, of an antimicrobial active; from about 4% to about 18%, by weight of the cleansing composition, of an anionic surfactant, wherein at least about 67% of the anionic surfactant is selected from the group consisting of Class A surfactants, Class C surfactants, and mixtures thereof, wherein the ratio of Class A surfactant to Class C is from about 100:0 to about 1.5:1; from about 0.1% to about 10%, by weight of the cleansing composition, of a Class D acidic surfactants; from 0.1% to about 8%, by weight of the cleansing composition, of a proton donating agent having a Biological Activity Index, Z, of greater than about 0.75, and wherein the proton donating agent is such that the composition is essentially free of C.sub.4 -C.sub.20 alkyl fatty acid; from about 67.0% to about 95.8%, by weight of the cleansing composition, of water; wherein the composition is adjusted to a pH of greater than about 3.0 and less than about 5.5; and wherein the ratio of the amount of non-anionic surfactants to the amount of anionic surfactant is less than 1:1. The invention also encompasses methods for cleansing skin and providing residual effectiveness versus Gram negative bacteria using these products.
摘要翻译：本发明涉及一种洗涤抗微生物清洁组合物，其包含按重量计约0.1％至约5.0％的清洁组合物的抗微生物活性物质; 约4％至约18％的所述清洁组合物的阴离子表面活性剂，其中至少约67％的阴离子表面活性剂选自A类表面活性剂，C类表面活性剂及其混合物，其中A类表面活性剂与C类的比例为约100：0至约1.5：1; 约0.1％至约10％的清洁组合物; D类酸性表面活性剂; 0.1重量％至约8重量％的清洁组合物，具有大于约0.75的生物活性指数Z的质子供体试剂，其中质子供体剂使得组合物基本上不含C4 -C 20烷基脂肪酸; 约为洗涤组合物重量的约67.0％至约95.8％的水; 其中将所述组合物调节至大于约3.0且小于约5.5的pH; 并且其中非阴离子表面活性剂的量与阴离子表面活性剂的量的比率小于1:1。本发明还包括使用这些产品的用于清洁皮肤并提供与革兰氏阴性细菌的残留效力的方法。

5. 发明授权

US6106851A Mild, rinse-off antimicrobial liquid cleansing compositions containing salicyclic acid 失效
标题翻译：含有水杨酸的轻度，漂洗的抗菌液体清洁组合物
公开(公告)号：US6106851A
公开(公告)日：2000-08-22
申请号：US323420
申请日：1999-06-01
申请人： Peter William Beerse , Jeffrey Michael Morgan , Kathleen Grieshop Baier , Robert Gregory Bartolo , Theresa Anne Bakken Schuette
发明人： Peter William Beerse , Jeffrey Michael Morgan , Kathleen Grieshop Baier , Robert Gregory Bartolo , Theresa Anne Bakken Schuette
IPC分类号： A61K8/00 , A61K8/33 , A61K8/49 , A61K8/58 , A61Q5/02 , A61Q19/10 , C11D1/02 , C11D3/20 , C11D3/24 , C11D3/28 , C11D3/32 , C11D3/48 , A61K6/00 , A61K7/075 , A61K7/40 , A61K31/05 , A61K31/075
CPC分类号： A61Q17/005 , A61K8/347 , A61K8/442 , A61K8/463 , A61K8/466 , A61Q19/10 , C11D3/2086 , C11D3/24 , C11D3/28 , C11D3/323 , C11D3/48 , A61K2800/596 , A61Q5/02 , C11D1/02 , Y10S514/846 , Y10S514/859 , Y10S514/941 , Y10S514/942
摘要： The present invention relates to a rinse-off antimicrobial cleansing composition comprising from about 0.1% to about 5.0%, by weight of the cleansing composition, of an antimicrobial active; from about 6% to about 16%, by weight of the cleansing composition, of an anionic surfactant, wherein at least about 67% of the anionic surfactant is selected from the group consisting of Class A surfactants, Class C surfactants, and mixtures thereof, wherein the ratio of Class A surfactant to Class C is from about 100:0 to about 1.5:1; from about 2% to about 4%, by weight of the cleansing composition, of a proton donating agent having a Biological Activity Index, Z, of greater than about 0.75, wherein the proton donating agent is such that the composition is essentially free of C.sub.4 -C.sub.20 alkyl fatty acid, and wherein from about 0.15% to about 2%, by weight of the cleansing composition, of the proton donating agent is salicylic acid; a mildness enhancing agent selected from the group consisting of from about 20% to about 70%, by weight of the anionic surfactant, of a mildness enhancing cosurfactant; from about 0.1% to about 1.0%, by weight of the cleansing composition, of a mildness enhancing polymer; and mixtures thereof, and from about 35% to about 95.75%, by weight of the cleansing composition, of water; wherein the composition is adjusted to a pH of greater than about 3 and less than about 6. The invention also encompasses methods for cleansing skin and providing residual effectiveness versus Gram negative bacteria using these products.
摘要翻译：本发明涉及一种洗涤抗微生物清洁组合物，其包含按重量计约0.1％至约5.0％的清洁组合物的抗微生物活性物质; 约6％至约16％的洗涤组合物的阴离子表面活性剂，其中至少约67％的阴离子表面活性剂选自A类表面活性剂，C类表面活性剂及其混合物，其中A类表面活性剂与C类的比例为约100：0至约1.5：1; 约2％至约4％的清洁组合物，具有大于约0.75的生物活性指数Z的质子供体，其中质子供体剂使得组合物基本上不含C4 -C 20烷基脂肪酸，其中约0.15重量％至约2重量％的所述清洁组合物的质子供体剂为水杨酸; 选自按重量计约20％至约70％的阴离子表面活性剂的温和增强助剂，具有温和增强助表面活性剂; 约0.1％至约1.0％的所述清洁组合物;增温聚合物; 和它们的混合物，和约35％至约95.75％重量的清洁组合物; 其中将组合物调节至大于约3且小于约6的pH。本发明还包括使用这些产品对革兰氏阴性细菌进行清洁皮肤并提供残留效力的方法。

6. 发明授权

US06344218B1 Skin deodorizing and santizing compositions 有权
标题翻译：皮肤除臭和精制组合物
公开(公告)号：US06344218B1
公开(公告)日：2002-02-05
申请号：US09321292
申请日：1999-05-27
申请人： Michael Thomas Dodd , Karl Shiqing Wei , Toan Trinh , Mark Richard Sine , Robert Gregory Bartolo , David Andrew Jakubovic
发明人： Michael Thomas Dodd , Karl Shiqing Wei , Toan Trinh , Mark Richard Sine , Robert Gregory Bartolo , David Andrew Jakubovic
IPC分类号： A61K732
CPC分类号： A61Q17/005 , A61K8/0208 , A61K8/27 , A61K8/347 , A61K8/40 , A61K8/416 , A61K8/43 , A61K8/4973 , A61K8/738 , A61K8/8147 , A61Q15/00
摘要： The present invention relates to aqueous compositions comprising an odor controlling agent and select sanitizing agents for deodorizing and sanitizing skin surfaces. Articles of manufacture and methods of deodorizing and sanitizing the skin using disclosed compositions are also disclosed.
摘要翻译：本发明涉及包含气味控制剂和用于除臭和消毒皮肤表面的选择性消毒剂的含水组合物。还公开了使用所公开的组合物的制品和使皮肤除臭和消毒的方法。

7. 发明授权

US06656456B2 Skin deodorizing compositions 有权
标题翻译：皮肤除臭组合物
公开(公告)号：US06656456B2
公开(公告)日：2003-12-02
申请号：US09443420
申请日：1999-11-19
申请人： Michael Thomas Dodd , Toan Trinh , Robert Gregory Bartolo , Karl Shiqing Wei , Mark Richard Sine , David Andrew Jakubovic
发明人： Michael Thomas Dodd , Toan Trinh , Robert Gregory Bartolo , Karl Shiqing Wei , Mark Richard Sine , David Andrew Jakubovic
IPC分类号： A61K736
CPC分类号： A61Q17/005 , A61K8/0208 , A61K8/042 , A61K8/27 , A61K8/347 , A61K8/40 , A61K8/416 , A61K8/43 , A61K8/4973 , A61K8/732 , A61K8/738 , A61K8/8147 , A61Q15/00
摘要： The present invention relates to aqueous gel compositions comprising an odor controlling agent for deodorizing skin surfaces. Articles of manufacture and methods of deodorizing the skin using disclosed compositions are also disclosed.
摘要翻译：本发明涉及包含用于使皮肤表面除臭的气味控制剂的含水凝胶组合物。还公开了使用公开的组合物制造皮肤和除臭方法的制品。

8. 发明授权

US5897856A Methods and compositions for reducing body odor 失效
标题翻译：减少体臭的方法和组合物
公开(公告)号：US5897856A
公开(公告)日：1999-04-27
申请号：US947076
申请日：1997-10-08
申请人： Toan Trinh , Robert Gregory Bartolo , Michael Thomas Dodd , Juliet Marie Lucas , Robin Yager Buckner , Theresa Marie Kajs
发明人： Toan Trinh , Robert Gregory Bartolo , Michael Thomas Dodd , Juliet Marie Lucas , Robin Yager Buckner , Theresa Marie Kajs
IPC分类号： A61K8/02 , A61K8/04 , A61K8/27 , A61K8/44 , A61K8/73 , A61K8/891 , A61Q15/00 , A61K7/32 , A61K33/10 , A61K33/24 , A61L9/01 , A61K25/00
CPC分类号： A61K8/046 , A61K8/0208 , A61K8/27 , A61K8/44 , A61K8/738 , A61K8/891 , A61Q15/00
摘要： The present invention relates to an odor-absorbing pre-formed wipe composition which is safe for use on human skin comprising from about 0.1% to about 5%, by weight of the composition, of solubilized, water-soluble, uncomplexed cyclodextrin; from about 0.01% to about 1%, by weight of the composition, of low molecular weight polyols; and an aqueous carrier, wherein the composition is deposited on a wipe which comprises a flexible dispensing means.The present invention also relates to methods of using the compositions of the present invention to reduce body odor and/or vaginal odor.
摘要翻译：本发明涉及一种安全用于人体皮肤的气味吸收预成型擦巾组合物，其包含按组合物重量计约0.1％至约5％的溶解的，水溶性的，未络合的环糊精; 按组合物重量计约0.01％至约1％的低分子量多元醇; 和水性载体，其中所述组合物沉积在包括柔性分配装置的擦拭物上。本发明还涉及使用本发明组合物来减少体臭和/或阴道气味的方法。

9. 发明授权

US5874070A Compositions for reducing body odor 失效
标题翻译：用于减少身体气味的组合物
公开(公告)号：US5874070A
公开(公告)日：1999-02-23
申请号：US871855
申请日：1997-06-09
申请人： Toan Trinh , Juliet Marie Lucas , Robert Gregory Bartolo , Michael Thomas Dodd , Robin Yager Buckner , Theresa Marie Kajs
发明人： Toan Trinh , Juliet Marie Lucas , Robert Gregory Bartolo , Michael Thomas Dodd , Robin Yager Buckner , Theresa Marie Kajs
IPC分类号： A61K8/02 , A61K8/19 , A61K8/27 , A61K8/34 , A61K8/37 , A61K8/44 , A61K8/49 , A61K8/73 , A61K8/891 , A61K8/90 , A61Q13/00 , A61Q15/00 , A61K7/32 , A61K33/10 , A61K33/24 , A61K25/00
CPC分类号： A61Q15/00 , A61K8/0208 , A61K8/19 , A61K8/27 , A61K8/347 , A61K8/37 , A61K8/44 , A61K8/4973 , A61K8/738 , A61K8/891 , A61K8/90 , A61Q13/00
摘要： The present invention relates to a perfumed aqueous, odor absorbing composition comprising from about 0.1% to about 5%, by weight of the composition, of solubilized, water-soluble, uncomplexed cyclodextrin; from about 0.5% to about 30%, by weight of the composition, of a linear dimethicone having a nominal viscosity of 350 centistokes or less; from about 0.004% to about 2%, by weight of the composition, of a perfume composition; and an aqueous carrier; wherein the perfume composition is safe for use on skin. The odor absorbing compositions of the present invention may also contain an effective amount of solubilized, water-soluble, antimicrobial.
摘要翻译：本发明涉及一种加香水性气味吸收组合物，其包含按组合物重量计约0.1％至约5％的溶解的水溶性未络合的环糊精; 约0.5重量％至约30重量％的标称粘度为350厘沲或更小的线性聚二甲基硅氧烷; 约0.004％至约2％（以重量计）的香料组合物; 和水性载体; 其中所述香料组合物可安全地用于皮肤上。本发明的气味吸收组合物还可含有有效量的溶解，水溶性，抗微生物剂。

10. 发明授权

US5928631A Methods for controlling environmental odors on the body using compositions comprising uncomplexed cyclodextrins 失效
标题翻译：使用包含未络合的环糊精的组合物来控制身体上环境气味的方法
公开(公告)号：US5928631A
公开(公告)日：1999-07-27
申请号：US871854
申请日：1997-06-09
申请人： Juliet Marie Lucas , Toan Trinh , Michael Thomas Dodd , Robert Gregory Bartolo
发明人： Juliet Marie Lucas , Toan Trinh , Michael Thomas Dodd , Robert Gregory Bartolo
IPC分类号： A47K7/00 , A61K8/00 , A61K8/18 , A61K8/19 , A61K8/25 , A61K8/27 , A61K8/33 , A61K8/34 , A61K8/37 , A61K8/44 , A61K8/49 , A61K8/73 , A61K8/86 , A61K8/89 , A61K8/891 , A61K8/90 , A61Q13/00 , A61Q15/00 , C08L83/10 , A61K7/00
CPC分类号： A61K8/39 , A61K8/19 , A61K8/27 , A61K8/347 , A61K8/37 , A61K8/44 , A61K8/4973 , A61K8/738 , A61K8/891 , A61K8/90 , A61Q15/00
摘要： The present invention encompasses a method of controlling environmental malodors on the body comprising the application to the skin of a composition comprising from about 0.1% to about 5%, by weight of the composition, of solubilized, water-soluble, uncomplexed cyclodextrin; from about 0.1% to about 36%, by weight of the composition, of an oil phase selected from the group consisting of emollients, moisturizers, and skin protectants; one or more surfactants each having a hydrophilic/lipophilic balance of about 8 to 18 and wherein each surfactant, when combined with an aqueous cyclodextrin solution, provides no less than 25% of odor capture as an aqueous cyclodextrin solution; and an aqueous carrier. The compositions can be applied directly as a spray, poured from a bottle and applied by hand, or applied via a wipe.
摘要翻译：本发明包括一种控制身体上的环境恶臭的方法，其包括对组合物施用至组合物的约0.1重量％至约5重量％的溶解的，水溶性的，未络合的环糊精; 约0.1％至约36％的组合物，选自润肤剂，保湿剂和皮肤保护剂的油相; 一种或多种表面活性剂各自具有约8至18的亲水/亲油平衡，并且其中当与水性环糊精溶液组合时，每种表面活性剂提供不少于25％的作为环糊精水溶液的气味捕获; 和水性载体。组合物可以直接作为喷雾施用，从瓶中倒出并用手施用，或通过擦拭物施用。

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