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1. 发明授权

US09862759B2 Method for generating and screening an antibody library 有权
公开(公告)号：US09862759B2
公开(公告)日：2018-01-09
申请号：US12745469
申请日：2008-12-04
申请人： Peter Lowe , Cédric Bes , Nicolas Boute
发明人： Peter Lowe , Cédric Bes , Nicolas Boute
IPC分类号： C12Q1/68 , C07K16/00
CPC分类号： C07K16/00 , C12Q1/68 , C12Q1/6844
摘要： The invention relates to a method for generating a DNA sequence coding for the heavy chain or the light chain of at least one antibody from RNA from a cell capable of producing an antibody. More particularly, the invention relates to the generation of a monoclonal antibody library. The invention also relates to the use of an antibody library for screening monoclonal antibodies, preferably human antibodies for treating cancer.

2. 发明申请

US20110003705A1 NOVEL METHOD FOR GENERATING AND SCREENING AN ANTIBODY LIBRARY 有权
标题翻译：用于生成和筛选抗体库的新方法
公开(公告)号：US20110003705A1
公开(公告)日：2011-01-06
申请号：US12745469
申请日：2008-12-04
申请人： Peter Lowe , Cédric Bes , Nicolas Boute
发明人： Peter Lowe , Cédric Bes , Nicolas Boute
IPC分类号： C40B30/04 , C12P19/34 , C12Q1/68 , C40B50/06
CPC分类号： C07K16/00 , C12Q1/68 , C12Q1/6844
摘要： The invention relates to a method for generating a DNA sequence coding for the heavy chain or the light chain of at least one antibody from RNA from a cell capable of producing an antibody. More particularly, the invention relates to the generation of a monoclonal antibody library. The invention also relates to the use of an antibody library for screening monoclonal antibodies, preferably human antibodies for treating cancer.
摘要翻译：本发明涉及从能够产生抗体的细胞的RNA产生编码至少一种抗体的重链或轻链的DNA序列的方法。更具体地，本发明涉及单克隆抗体文库的产生。本发明还涉及抗体文库用于筛选单克隆抗体，优选人抗体用于治疗癌症的用途。

3. 发明授权

US5772061A Refuse containers 失效
标题翻译：垃圾箱
公开(公告)号：US5772061A
公开(公告)日：1998-06-30
申请号：US571810
申请日：1995-12-13
申请人： Peter Lowe
发明人： Peter Lowe
IPC分类号： B65F1/16 , E05B15/00 , B65D51/18
CPC分类号： E05B15/0093 , B65F1/1615 , Y10S220/908
摘要： A gravity catch for a refuse container allows the lid to open only when the container is upended for emptying. The catch includes a sliding/rolling locking member which is also the gravity element.
摘要翻译：用于垃圾容器的重力捕获器允许盖子仅在容器升高以便排空时打开。卡扣包括滑动/滚动锁定构件，其也是重力元件。

4. 外观设计

USD334542S Housing for a control panel 失效
公开(公告)号：USD334542S
公开(公告)日：1993-04-06
申请号：US614745
申请日：1990-11-16
申请人： Peter Lowe , Peter Muller
设计人： Peter Lowe , Peter Muller

5. 发明申请

US20120322678A1 NOVEL PHAGE DISPLAY VECTOR 有权
标题翻译：新款PHAGE显示矢量图
公开(公告)号：US20120322678A1
公开(公告)日：2012-12-20
申请号：US13510148
申请日：2010-11-18
申请人： Peter Lowe , Sven Berger
发明人： Peter Lowe , Sven Berger
IPC分类号： C12N15/70 , C12N15/71 , C40B30/04 , C12N15/72 , C40B40/02 , C40B50/06
CPC分类号： C12N15/1037 , C12N15/86 , C12N2795/14143
摘要： The invention relates to a minimized phage display vector comprising at least a cloning cassette, a phage display cassette and a bacterial cassette, said cloning cassette comprising a nucleic acid sequence encoding a polypeptide corresponding at least to the intra-domain loop of a constant domain of an antibody. It also relates to their uses for the production of libraries of phages, each phage expressing on its surface a binding protein to be screened for its capacity to bind a binding partner.
摘要翻译：本发明涉及包含至少一个克隆盒，噬菌体展示盒和细菌盒的最小化的噬菌体展示载体，所述克隆盒包含编码多肽的核酸序列，所述核酸序列至少对应于恒定结构域的恒定结构域的域内环抗体。它还涉及其用于生产噬菌体文库的用途，每个噬菌体在其表面上表达一种结合蛋白质，以筛选其结合配偶体的结合能力。

6. 发明申请

US20070229273A1 Detection signal generator circuit for an RFID reader 有权
标题翻译：用于RFID读取器的检测信号发生器电路
公开(公告)号：US20070229273A1
公开(公告)日：2007-10-04
申请号：US11396290
申请日：2006-03-31
申请人： James Hoemann , Peter Lowe
发明人： James Hoemann , Peter Lowe
IPC分类号： G08B13/14
CPC分类号： G06K7/0008 , G06K7/0086 , G06K7/10009 , G06K7/10128
摘要： An RFID transponder detector is provided having a coupled oscillator system. Coupled first and second LC pairs of the system produce a detection signal each time a combination of pulses is applied to the LC pairs. Application of the pulses is repeated periodically to produce a sequence fo detection signals having two different first and second detection frequencies. Transmitting the sequence of detection signals results in corresponding first and second response signals having the first and second detection frequencies at the LC pairs. Values of a preselected detection parameter for the detection signals are compared to the values of the detection parameter for the response signals to determine if a transponder having a transponder resonant frequency corresponding to the first or second detection frequency is present in a proximal space of the transponder detector.
摘要翻译：提供了具有耦合振荡器系统的RFID应答器检测器。每当脉冲组合施加到LC对时，系统的耦合的第一和第二LC对产生检测信号。周期性地重复脉冲的应用以产生具有两个不同的第一和第二检测频率的检测信号序列。发送检测信号的序列导致在LC对具有第一和第二检测频率的对应的第一和第二响应信号。将检测信号的预选检测参数的值与响应信号的检测参数的值进行比较，以确定具有与第一或第二检测频率相对应的应答器谐振频率的应答器是否存在于应答器的近端空间中探测器。

7. 发明授权

US08728983B2 Phage display vector 有权
标题翻译：噬菌体展示载体
公开(公告)号：US08728983B2
公开(公告)日：2014-05-20
申请号：US13510148
申请日：2010-11-18
申请人： Peter Lowe , Sven Berger
发明人： Peter Lowe , Sven Berger
IPC分类号： C40B40/08
CPC分类号： C12N15/1037 , C12N15/86 , C12N2795/14143
摘要： The invention relates to a minimized phage display vector comprising at least a cloning cassette, a phage display cassette and a bacterial cassette, said cloning cassette comprising a nucleic acid sequence encoding a polypeptide corresponding at least to the intra-domain loop of a constant domain of an antibody. It also relates to their uses for the production of libraries of phages, each phage expressing on its surface a binding protein to be screened for its capacity to bind a binding partner.
摘要翻译：本发明涉及包含至少一个克隆盒，噬菌体展示盒和细菌盒的最小化的噬菌体展示载体，所述克隆盒包含编码多肽的核酸序列，所述核酸序列至少对应于恒定结构域的恒定结构域的域内环抗体。它还涉及其用于生产噬菌体文库的用途，每个噬菌体在其表面上表达一种结合蛋白质，以筛选其结合配偶体的结合能力。

8. 发明申请

US20050253683A1 Biometrically authenticated portable access device 失效
标题翻译：生物认证便携式接入设备
公开(公告)号：US20050253683A1
公开(公告)日：2005-11-17
申请号：US10847542
申请日：2004-05-17
申请人： Peter Lowe
发明人： Peter Lowe
IPC分类号： G05B19/00 , G06F21/00 , G06K19/07 , G06K19/073 , G07C9/00 , H04Q1/00
CPC分类号： G07C9/00087 , G06F21/32 , G06K19/0723 , G06K19/07354 , G07C2009/00095
摘要： A biometrically authenticated portable access device, includes a biometric sensor for measuring a live biometric parameter of an unverified user, an authenticator controlling a switch that enables and disables a conventional RFID tag and a stored biometric template corresponding to a previously measured biometric parameter of an authorized user. The authenticator compares the live biometric parameter of the unverified user to the stored biometric template and enables the RFID tag when the live biometric parameter matches the stored biometric template. The RFID tag is programmable in conventional RFID tag programmers that may be proprietary permitting the portable access device to be used with existing installed systems of proprietary and non-proprietary RFID tag programmers and readers.
摘要翻译：生物测定认证的便携式存取装置包括用于测量未经验证的用户的实时生物特征参数的生物测定传感器，控制启用和禁用常规RFID标签的开关的认证器，以及对应于经授权的先前测量的生物特征参数的存储的生物测定模板用户。认证者将未验证用户的实时生物特征参数与存储的生物特征模板进行比较，并且当活体生物特征参数与存储的生物特征模板匹配时启用RFID标签。 RFID标签可以在传统的RFID标签编程器中编程，其可以是专有的，允许便携式接入设备与已经安装的专有和非专有RFID标签程序员和读取器的系统一起使用。

9. 外观设计

USD814091S1 Lamp 有权
公开(公告)号：USD814091S1
公开(公告)日：2018-03-27
申请号：US29586838
申请日：2016-12-07
申请人： Peter Lowe
设计人： Peter Lowe

10. 发明申请

US20060224901A1 System and method for remotely assigning and revoking access credentials using a near field communication equipped mobile phone 有权
标题翻译：使用配备有近场通信的移动电话远程分配和撤销访问凭据的系统和方法
公开(公告)号：US20060224901A1
公开(公告)日：2006-10-05
申请号：US11397542
申请日：2006-04-03
申请人： Peter Lowe
发明人： Peter Lowe
IPC分类号： H04L9/00
CPC分类号： G06F21/31 , G06F21/45 , G07C9/00007 , H04L63/0492 , H04L63/062 , H04L63/068 , H04L63/08 , H04L63/0853 , H04L63/10 , H04W4/023 , H04W4/80 , H04W12/04 , H04W12/06 , H04W12/08 , H04W48/04 , H04W88/02
摘要： The present invention is generally directed toward a mobile device that can be used in a secure access system. More specifically, the mobile device can have credential data loaded thereon remotely updated, enabled, disabled, revoked, or otherwise altered with a message sent from, for example, a control panel and/or controller in the system.
摘要翻译：本发明通常涉及可以用在安全接入系统中的移动设备。更具体地说，移动设备可以使用从系统中的例如控制面板和/或控制器发送的消息，使用其上加载的凭证数据进行远程更新，启用，禁用，撤销或以其它方式改变。

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