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1. 发明授权

US08399523B2 Quarternization of the additive amino alkylmethacrylate copolymer E for improving permeability and solubility of pharmaceuticals 有权
标题翻译：氨基甲基丙烯酸烷基酯共聚物E的改性，用于提高药物的渗透性和溶解度
公开(公告)号：US08399523B2
公开(公告)日：2013-03-19
申请号：US12747722
申请日：2008-12-12
申请人： Peter Langguth , Stefan Grube , Holger Frey , Boris Obermeier
发明人： Peter Langguth , Stefan Grube , Holger Frey , Boris Obermeier
IPC分类号： A61K47/32 , C08F26/02
CPC分类号： A61K47/32 , C08F26/02 , C08F220/10 , C08F220/34
摘要： The present invention relates to a strategy for improving the permeability and solubility of pharmaceuticals, based on adding a chemically modified amino alkyl methacrylate copolymer E, wherein the chemical modification is the quaternization of a fraction of the existing amino alkyl groups.
摘要翻译：本发明涉及基于加入化学修饰的氨基甲基丙烯酸烷基酯共聚物E来提高药物的渗透性和溶解度的策略，其中化学修饰是一部分现有氨基烷基的季铵化。

2. 发明申请

US20100286288A1 QUARTERNIZATION OF THE ADDITIVE AMINO ALKYLMETHACRYLATE COPOLYMER E FOR IMPROVING PERMEABILITY AND SOLUBILITY OF PHARMACEUTICALS 有权
标题翻译：用于改善药物渗透性和溶解性的添加剂氨基甲基丙烯酸甲酯共聚物E的分级
公开(公告)号：US20100286288A1
公开(公告)日：2010-11-11
申请号：US12747722
申请日：2008-12-12
申请人： Peter Langguth , Stefan Grube , Holger Frey , Boris Obermeier
发明人： Peter Langguth , Stefan Grube , Holger Frey , Boris Obermeier
IPC分类号： A61K47/32 , C08F26/02
CPC分类号： A61K47/32 , C08F26/02 , C08F220/10 , C08F220/34
摘要： The present invention relates to a strategy for improving the permeability and solubility of pharmaceuticals, based on adding a chemically modified amino alkyl methacrylate copolymer E, wherein the chemical modification is the quaternization of a fraction of the existing amino alkyl groups.
摘要翻译：本发明涉及基于加入化学修饰的氨基甲基丙烯酸烷基酯共聚物E来提高药物的渗透性和溶解度的策略，其中化学修饰是一部分现有氨基烷基的季铵化。

3. 发明授权

US09458029B2 Separator for separating a light liquid-water mixture and method for separating a light liquid-water mixture 有权
标题翻译：用于分离轻液水混合物的分离器和用于分离轻液 - 水混合物的方法
公开(公告)号：US09458029B2
公开(公告)日：2016-10-04
申请号：US13821348
申请日：2011-09-07
申请人： Hermann Mayer , Marc Schmitz , Stefan Grube , Libor Docekal
发明人： Hermann Mayer , Marc Schmitz , Stefan Grube , Libor Docekal
IPC分类号： C02F1/00 , B01D17/02
CPC分类号： C02F1/006 , B01D17/0211
摘要： A separator is indicated, which is arranged in a container having a circular or ellipsoidal cross section and having a container wall, for separating a light liquid-water mixture, for example oil-polluted water, comprising: a feed arranged on a first side of the container having a feed chicane, which directs the supplied mixture downward and divides it into two first flow parts that are substantially of equal size, an outlet having an outlet tube, a circular or ellipsoidal flow wall having an internal wall side and an external wall side, wherein the flow wall passes through at least half of a full circle, preferably at least three quarters of a full circle, and has an opening, which is facing a second side of the container opposite the feed, wherein the flow wall between the external wall side of the flow wall and the container wall forms two flow channels at two opposite sides of the container wall in each case from the feed to the second side of the container, wherein in the flow channels in each case one of the two first flow parts is conducted from the feed to the second side of the container along the container wall, wherein the two first flow parts at the second side of the container having substantially opposite directions of flow meet one another and are reunited, and hole elements arranged in the two flow channels through which the two first flow parts flow.
摘要翻译：指示分离器，其布置在具有圆形或椭圆形横截面并具有容器壁的容器中，用于分离轻液体 - 水混合物，例如油污水，包括：设置在第一侧的进料所述容器具有进料通道，其将所提供的混合物向下引导并将其分成两个基本上相同尺寸的第一流动部分，具有出口管，具有内壁侧的圆形或椭圆形流动壁的出口和外壁侧壁，其中流动壁穿过整圆的至少一半，优选地至少四分之三的整圆，并且具有面向容器相对于进料的第二侧的开口，其中，流动壁的外壁侧和容器壁在容器壁的两个相对的两侧形成两个流动通道，从每个壳体的进料到容器的第二侧，其中在流动在每种情况下，两个第一流动部分中的一个沿着容器壁从进料传送到容器的第二侧，其中具有基本上相反的流动方向的容器的第二侧处的两个第一流动部分彼此相遇并且重新排列，并且布置在两个流动通道中的孔元件，两个第一流动部分通过该孔流动。

4. 发明申请

US20130306577A1 SEPARATOR FOR SEPARATING A LIGHT LIQUID-WATER MIXTURE AND METHOD FOR SEPARATING A LIGHT LIQUID-WATER MIXTURE 有权
标题翻译：用于分离轻液水混合物的分离器和用于分离轻液水混合物的方法
公开(公告)号：US20130306577A1
公开(公告)日：2013-11-21
申请号：US13821348
申请日：2011-09-07
申请人： Hermann Mayer , Marc Schmitz , Stefan Grube , Libor Docekal
发明人： Hermann Mayer , Marc Schmitz , Stefan Grube , Libor Docekal
IPC分类号： C02F1/00
CPC分类号： C02F1/006 , B01D17/0211
摘要： A separator is indicated, which is arranged in a container having a circular or ellipsoidal cross section and having a container wall, for separating a light liquid-water mixture, for example oil-polluted water, comprising: a feed arranged on a first side of the container having a feed chicane, which directs the supplied mixture downward and divides it into two first flow parts that are substantially of equal size, an outlet having an outlet tube, a circular or ellipsoidal flow wall having an internal wall side and an external wall side, wherein the flow wall passes through at least half of a full circle, preferably at least three quarters of a full circle, and has an opening, which is facing a second side of the container opposite the feed, wherein the flow wall between the external wall side of the flow wall and the container wall forms two flow channels at two opposite sides of the container wall in each case from the feed to the second side of the container, wherein in the flow channels in each case one of the two first flow parts is conducted from the feed to the second side of the container along the container wall, wherein the two first flow parts at the second side of the container having substantially opposite directions of flow meet one another and are reunited, and hole elements arranged in the two flow channels through which the two first flow parts flow.
摘要翻译：指示分离器，其布置在具有圆形或椭圆形横截面并具有容器壁的容器中，用于分离轻液体 - 水混合物，例如油污水，包括：设置在第一侧的进料所述容器具有进料通道，其将所提供的混合物向下引导并将其分成两个基本上相同尺寸的第一流动部分，具有出口管，具有内壁侧的圆形或椭圆形流动壁的出口和外壁侧壁，其中流动壁穿过整圆的至少一半，优选地至少四分之三的整圆，并且具有面向容器相对于进料的第二侧的开口，其中，流动壁的外壁侧和容器壁在容器壁的两个相对的两侧形成两个流动通道，从每个壳体的进料到容器的第二侧，其中在流动在每种情况下，两个第一流动部分中的一个沿着容器壁从进料传送到容器的第二侧，其中具有基本上相反的流动方向的容器的第二侧处的两个第一流动部分彼此相遇并且重新排列，并且布置在两个流动通道中的孔元件，两个第一流动部分通过该孔流动。

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