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1. 发明授权

US09295626B2 Compositions comprising isosorbide monoester and N-hydroxypyridones 有权
标题翻译：包含异山梨醇酯单酯和N-羟基吡啶酮的组合物
公开(公告)号：US09295626B2
公开(公告)日：2016-03-29
申请号：US14237024
申请日：2012-07-31
申请人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
发明人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
IPC分类号： A61K8/49 , A01N43/90 , A61Q1/14 , A61Q5/00 , A61Q5/02 , A61Q5/06 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/04 , A61Q19/08 , A61Q19/10
CPC分类号： A61K8/4973 , A01N43/90 , A61K8/4926 , A61K2300/00 , A61Q1/02 , A61Q1/14 , A61Q5/006 , A61Q5/02 , A61Q5/06 , A61Q15/00 , A61Q17/005 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/04 , A61Q19/08 , A61Q19/10 , A01N43/40 , A01N2300/00 , A01N43/10
摘要： What are described are compositions comprising a) one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms, and b) one or more substances selected from the group consisting of hydroxypyridones and their salts. The compositions are distinguished in particular by an advantageous antimicrobial activity.
摘要翻译：描述的组合物包含a）一种或多种式（I）化合物，其中R是具有5至11个碳原子的直链或支链饱和烷基或直链或支链单或多不饱和烯基具有5至11个碳原子，和b）一种或多种选自羟基吡啶酮及其盐的物质。特别地，组合物通过有利的抗微生物活性来区分。

2. 发明申请

US20140369943A1 COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND HALOGENATED ANTIMICROBIAL ACTIVE COMPOUNDS 审中-公开
标题翻译：包含异构体单体和组分的抗坏血酸活性化合物
公开(公告)号：US20140369943A1
公开(公告)日：2014-12-18
申请号：US14237053
申请日：2012-07-31
申请人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
发明人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
IPC分类号： A61Q19/10 , A61K31/047 , A61Q5/06 , A61K8/49 , A61K8/40 , A61K8/19 , A61K8/31 , A61K8/92 , A61K8/34 , A61K8/96 , A61K8/86 , A61K8/44 , A61K8/58 , A61K8/365 , A61K8/46 , A61Q19/00 , A61K8/25 , A61K8/36 , A61K8/37 , A61Q19/02 , A61K8/73 , A61K8/60 , A61K8/362 , A61Q19/08 , A61K8/35 , A61K8/29 , A61K8/22 , A61Q19/04 , A61Q17/04 , A61K8/368 , A61K8/41 , A61K8/55 , A61K8/81 , A61Q1/02 , A61K8/26 , A61Q5/00 , A61K8/20 , A01N43/90 , A01N33/18 , C11D3/48 , C11D3/20 , C09D133/08 , C09D133/02 , C09D131/04 , A61K31/34
CPC分类号： A61Q19/10 , A01N33/18 , A01N43/90 , A61K8/19 , A61K8/20 , A61K8/22 , A61K8/25 , A61K8/26 , A61K8/29 , A61K8/31 , A61K8/34 , A61K8/342 , A61K8/345 , A61K8/35 , A61K8/355 , A61K8/361 , A61K8/362 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/418 , A61K8/44 , A61K8/463 , A61K8/466 , A61K8/4913 , A61K8/4946 , A61K8/4966 , A61K8/4973 , A61K8/498 , A61K8/55 , A61K8/585 , A61K8/602 , A61K8/73 , A61K8/8135 , A61K8/817 , A61K8/86 , A61K8/92 , A61K8/96 , A61K31/047 , A61K31/34 , A61Q1/02 , A61Q1/14 , A61Q5/006 , A61Q5/02 , A61Q5/06 , A61Q15/00 , A61Q17/005 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/04 , A61Q19/08 , C09D131/04 , C09D133/02 , C09D133/08 , C11D3/2096 , C11D3/48 , C11D3/485 , A01N35/08 , A01N47/12 , A01N2300/00
摘要： What are described are compositions comprising a) one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms, and b) one or more halogenated antimicrobially active compounds. The compositions are distinguished in particular by an advantageous antibacterial activity.
摘要翻译：描述的组合物包含a）一种或多种式（I）化合物，其中R是具有5至11个碳原子的直链或支链饱和烷基或直链或支链单或多不饱和烯基具有5至11个碳原子，和b）一种或多种卤化的抗微生物活性化合物。特别地，组合物通过有利的抗菌活性来区分。

3. 发明授权

US08686033B2 Phosphoric acid esters containing phosphorus atoms bridged by diol units 失效
标题翻译：含有由二醇单元桥连的磷原子的磷酸酯
公开(公告)号：US08686033B2
公开(公告)日：2014-04-01
申请号：US12671422
申请日：2008-07-29
申请人： Peter Klug , Franz-Xaver Scherl , Waltraud Simsch , Adelgunde Oberhauser
发明人： Peter Klug , Franz-Xaver Scherl , Waltraud Simsch , Adelgunde Oberhauser
IPC分类号： A61K33/42 , C07F9/02
CPC分类号： C08G65/327 , A61K8/86 , A61K8/90 , A61K2800/48 , A61K2800/52 , A61Q5/02 , A61Q19/00 , C08G65/3312 , C08G65/3353 , C08L71/02
摘要： Phosphoric esters comprise A) one or more structural units derived from substances of component a), the substances of component a) being selected from orthophosphoric acid and one or more of its derivatives, B) one or more structural units derived from substances of component b), the substances of component b) being selected from one or more compounds of formula (I) R2—O—(CH2CH2O)u(C3H6O)v(DO)w—H (I) and C) one or more structural units derived from substances of component c), the substances of component c) being selected from one or more diols of formula (II) HO—(CH2CH2O)a(C3H6O)b(DO)c—H (II) where the sum total a+b+c is ≧1, and the phosphoric ester contains 2 or more phosphorus atoms per molecule which are bridged via a structural unit derived from the compounds of formula (II). The phosphoric esters of the invention are very useful in the manufacture of cosmetic, pharmaceutical and dermatological compositions.
摘要翻译：磷酸酯包括A）一种或多种衍生自组分a）的物质的结构单元，组分a）的物质选自正磷酸及其一种或多种衍生物，B）一种或多种衍生自组分b的物质的结构单元），组分b）的物质选自一种或多种式（I）R 2 -O-（CH 2 CH 2 O）u（C 3 H 6 O）v（DO）w-H（I））的化合物和C）一种或多种衍生的结构单元从组分c）的物质中，组分c）的物质选自一种或多种式（II）的二醇HO-（CH 2 CH 2 O）a（C 3 H 6 O）b（DO）c-H（II），其中总和a + b + c为≥1，磷酸酯每分子含有2个以上的磷原子，该磷原子通过衍生自式（II）化合物的结构单元桥连。本发明的磷酸酯在制造化妆品，药物和皮肤病学组合物中非常有用。

4. 发明申请

US20110003010A1 Phosphoric Acid Esters Containing Phosphorus Atoms Bridged By Diol Units 失效
标题翻译：含有由二醇单元桥接的磷原子的磷酸酯
公开(公告)号：US20110003010A1
公开(公告)日：2011-01-06
申请号：US12671422
申请日：2008-07-29
申请人： Peter Klug , Franz-Xaver Scherl , Waltraud Simsch , Adelgunde Oberhauser
发明人： Peter Klug , Franz-Xaver Scherl , Waltraud Simsch , Adelgunde Oberhauser
IPC分类号： A61K31/765 , C07F9/11 , A61K8/86 , A61K8/55 , A61K31/6615 , A61K31/661 , A61P31/00 , A61K33/40 , A61Q5/00 , A61Q19/00 , A61Q15/00 , A61Q1/00 , C11D3/36 , A61Q19/10
CPC分类号： C08G65/327 , A61K8/86 , A61K8/90 , A61K2800/48 , A61K2800/52 , A61Q5/02 , A61Q19/00 , C08G65/3312 , C08G65/3353 , C08L71/02
摘要： Phosphoric esters comprise A) one or more structural units derived from substances of component a), the substances of component a) being selected from orthophosphoric acid and one or more of its derivatives, B) one or more structural units derived from substances of component b), the substances of component b) being selected from one or more compounds of formula (I) R2—O—(CH2CH2O)u(C3H6O)v(DO)w—H (I) and C) one or more structural units derived from substances of component c), the substances of component c) being selected from one or more diols of formula (II) HO—(CH2CH2O)a(C3H6O)b(DO)c—H (II) where the sum total a+b+c is ≧1 and the phosphoric ester contains 2 or more phosphorus atoms per molecule which are bridged via a structural unit derived from the compounds of formula (II).The phosphoric esters of the invention are very useful in the manufacture of cosmetic, pharmaceutical and dermatological compositions.
摘要翻译：磷酸酯包括A）一种或多种衍生自组分a）的物质的结构单元，组分a）的物质选自正磷酸及其一种或多种衍生物，B）一种或多种衍生自组分b的物质的结构单元），组分b）的物质选自一种或多种式（I）R 2 -O-（CH 2 CH 2 O）u（C 3 H 6 O）v（DO）w-H（I））的化合物和C）一种或多种衍生的结构单元从组分c）的物质中，组分c）的物质选自一种或多种式（II）的二醇HO-（CH 2 CH 2 O）a（C 3 H 6 O）b（DO）c-H（II），其中总和a + b + c为≥1，磷酸酯每分子含有2个或更多个磷原子，该磷原子通过衍生自式（II）化合物的结构单元桥连。本发明的磷酸酯在制造化妆品，药物和皮肤病学组合物中非常有用。

5. 发明申请

US20100260696A1 Aqueous Compositions Containing Alkoxylated Phosphoric Acid Triesters 审中-公开
标题翻译：含有烷氧基化磷酸三酯的水性组合物
公开(公告)号：US20100260696A1
公开(公告)日：2010-10-14
申请号：US12671441
申请日：2008-07-29
申请人： Peter Klug , Franz-Xaver Scherl , Waltraud Simsch , Adelgunde Oberhauser
发明人： Peter Klug , Franz-Xaver Scherl , Waltraud Simsch , Adelgunde Oberhauser
IPC分类号： A61K8/55 , A61K47/24 , A61Q15/00 , A61P17/00 , A61P43/00
CPC分类号： C08L71/02 , A61K8/86 , A61Q1/14 , A61Q5/02 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/04 , A61Q19/08 , A61Q19/10 , B01F17/0064 , C08G65/327 , C08G65/3312 , C08G65/3353
摘要： The invention relates to compositions containing A) at least one phosphoric acid ester of formula (I) wherein R1, R2 and R3 can be the same or different and stand for a linear or branched, saturated alkyl group comprising between 6 and 30 carbon atoms, a linear or branched, monounsaturated or polyunsaturated alkenyl group comprising between 6 and 30 carbon atoms, or an aryl group that can be substituted with between 1 and 3 branched alkyl groups each independently containing between 3 and 18 carbon atoms, the individual groups (OA1)x, (A2O)y and (A3O)z each independently consisting of units selected from CH2CH2O, C3H6O and C4H8O, the units CH2CH2O, C3H6O and C4H8O being arranged inside the individual groups (OA1)X, (A2O)y and (A3O), in blocks or in a statistically distributed manner, and x, y and z each independently standing for a number between 30 and 150, and B); water in a proportion of >50.0 wt. % in relation to the finished composition. The compositions according to the invention are preferably cosmetic, pharmaceutical or dermatological compositions.
摘要翻译：本发明涉及包含A）至少一种式（I）的磷酸酯的组合物，其中R 1，R 2和R 3可以相同或不同，代表包含6至30个碳原子的直链或支链饱和烷基，包含6至30个碳原子的直链或支链单不饱和或多不饱和链烯基，或可被1至3个各自独立地含有3至18个碳原子的支链烷基取代的芳基，各基团（OA1） x，（A 2 O）y和（A3O）z各自独立地由选自CH 2 CH 2 O，C 3 H 6 O和C 4 H 8 O的单元组成，单元CH 2 CH 2 O，C 3 H 6 O和C 4 H 8 O设置在各组（OA1）X，（A2O）y和（A3O）以块或统计分布的方式，x，y和z各自独立地代表30到150之间的数字，B）; 水比例> 50.0wt。相对于成品组成的百分比。根据本发明的组合物优选为化妆品，药物或皮肤病学组合物。

6. 发明申请

US20050112081A1 Liquid compositions comprising oxyalkylated polyglycerol esters 有权
标题翻译：包含烷氧基化聚甘油酯的液体组合物
公开(公告)号：US20050112081A1
公开(公告)日：2005-05-26
申请号：US10940840
申请日：2004-09-14
申请人： Matthias Loeffler , Peter Klug , Franz-Xaver Scherl
发明人： Matthias Loeffler , Peter Klug , Franz-Xaver Scherl
IPC分类号： A61K47/34 , A61K8/00 , A61K8/02 , A61K8/06 , A61K8/39 , A61K8/72 , A61K8/86 , A61Q5/02 , A61Q19/10 , C08G65/34 , C08J3/02 , C08L71/02 , C09K3/00 , C11D1/66 , C11D3/43 , A61K7/075 , A61K7/08
CPC分类号： C08L71/02 , A61K8/39 , A61K8/86 , A61Q5/02 , A61Q19/10 , C08G65/34 , C08J3/02 , C08J2371/02 , Y10S514/941
摘要： Compositions are described which comprise oxyalkylated polyglycerol esters, one or more organic solvents and water. The compositions are exceptionally suitable for the thickening of surfactant-containing systems.
摘要翻译：描述了包含烷氧基化聚甘油酯，一种或多种有机溶剂和水的组合物。该组合物特别适用于含表面活性剂的体系的增稠。

7. 发明授权

US10406135B2 Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group 有权
公开(公告)号：US10406135B2
公开(公告)日：2019-09-10
申请号：US14237028
申请日：2012-07-31
申请人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
发明人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
IPC分类号： A61K31/343 , A01N37/10 , A01N39/00 , A01N43/90 , A01N31/14 , A61K8/34 , A61K8/49 , A61K31/045 , A61Q1/00 , A61Q5/06 , A61Q19/00 , A61Q19/04 , A61Q1/14 , A61Q5/02 , A61Q15/00 , A61Q17/04 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61Q1/02
摘要： Compositions comprising isosorbide monoesters and alcohols comprising at least one aromatic groupWhat are described are compositions comprising a) one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms, and b) one or more alcohols comprising at least one aromatic group. The compositions are distinguished in particular by an advantageous antimicrobial activity.

8. 发明授权

US09662287B2 Process for preparing acylglycinates and compositions comprising such compounds 有权
公开(公告)号：US09662287B2
公开(公告)日：2017-05-30
申请号：US14232844
申请日：2012-07-11
申请人： Peter Klug , Franz-Xaver Scherl
发明人： Peter Klug , Franz-Xaver Scherl
IPC分类号： A61K8/42 , C07C233/47 , A61Q19/00 , C07C233/49 , A61Q19/10 , A61K8/04 , A61K8/44 , C07C231/02
CPC分类号： C07C231/02 , A61K8/046 , A61K8/42 , A61K8/44 , A61K8/442 , A61K2800/10 , A61Q19/00 , A61Q19/10 , C07C233/47 , C07C233/49 , C07C233/02
摘要： A process for preparing acylglycinates of the formula (I) wherein R1 is a linear or branched, saturated alkanoyl group having 6 to 30 carbon atoms, or is a linear or branched, singly or multiply unsaturated alkenoyl group having 6 to 30 carbon atoms, and Q+ is a cation, wherein glycine is reacted with fatty acid chloride R1Cl, in water and in the presence of a basic alkali metal compound which yields cations Q+, but in the absence of organic solvents, at 25-50° C. Also described are compositions comprising acylglycinates of the formula (I).

9. 发明授权

US09555117B2 Use of isosorbide monoesters as thickeners 有权
标题翻译：使用异山梨醇单酯作为增稠剂
公开(公告)号：US09555117B2
公开(公告)日：2017-01-31
申请号：US14237042
申请日：2012-07-31
申请人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl
发明人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl
IPC分类号： A61K31/34 , A61K47/22 , C09D7/00 , C11D3/22 , C11D17/00 , A01N43/90 , A01N25/00 , A61K8/49 , A61Q5/02 , A61Q19/10 , C09D7/12 , C11D3/20 , A61K8/04
CPC分类号： A61K47/22 , A01N25/00 , A01N43/90 , A61K8/042 , A61K8/4973 , A61K2800/10 , A61K2800/48 , A61Q5/02 , A61Q19/10 , C09D7/43 , C09D7/63 , C11D3/2096 , C11D3/221 , C11D17/003
摘要： The use of one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms as thickeners is described. The use is preferably in cosmetic, dermatological or pharmaceutical compositions, in crop protection formulations, in washing or cleaning compositions or in paints or coatings.
摘要翻译：优选使用化妆品，皮肤病学或药物组合物，作物保护制剂，洗涤或清洁组合物或涂料或涂料中。

10. 发明授权

US09445595B2 Composition containing isosorbide monoester and isosorbide diester 有权
标题翻译：含异山梨醇单酯和异山梨醇二酯的组合物
公开(公告)号：US09445595B2
公开(公告)日：2016-09-20
申请号：US14237071
申请日：2012-07-31
申请人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
发明人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
IPC分类号： A61K31/34 , A01N43/90 , C07D493/04 , A01N25/04 , C11D1/66 , C11D3/20 , C11D3/22 , A61K8/49 , A61Q19/00 , C09D7/12
CPC分类号： A61K8/4973 , A01N25/04 , A01N43/90 , A61K2800/10 , A61K2800/48 , A61K2800/524 , A61Q19/00 , A61Q19/007 , C09D7/61 , C09D7/63 , C11D1/143 , C11D1/667 , C11D1/75 , C11D1/83 , C11D3/2096 , C11D3/221 , C11D3/48 , A01N43/70
摘要： What are described are compositions comprising one or more compounds of the formula (I) and one or more compounds of the formula (II) in which R, Ra and Rb each independently of one another are straight-chain or branched saturated alkyl groups having 5 to 11 carbon atoms or straight-chain or branched mono- or polyunsaturated alkenyl groups having 5 to 11 carbon atoms, wherein the total amount of the compounds of the formulae (I) and (II), based on the total weight of the compositions, is at least 60% by weight. In an advantageous manner, the compositions are suitable for producing cosmetic, dermatological or pharmaceutical compositions, crop protection formulations, washing or cleaning compositions or paints or coatings.
摘要翻译：以有利的方式，组合物适用于生产化妆品，皮肤病学或药物组合物，作物保护制剂，洗涤或清洁组合物或油漆或涂料。

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