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1. 发明申请

US20130102067A1 CELL MONITORING BY MEANS OF SCATTERED LIGHT MEASUREMENT 审中-公开
标题翻译：通过散射光测量的细胞监测
公开(公告)号：US20130102067A1
公开(公告)日：2013-04-25
申请号：US13806505
申请日：2011-04-05
申请人： Peter Ertl , Oliver Hayden , Kriemhilt Roppert , Sandro Francesco Tedde
发明人： Peter Ertl , Oliver Hayden , Kriemhilt Roppert , Sandro Francesco Tedde
IPC分类号： G01N21/47
CPC分类号： G01N21/47 , C12M41/46 , G01N21/51 , G01N2021/058 , G01N2021/4707
摘要： A device for monitoring test cells has at least one receiving unit for the test cells and a first measuring unit for cell measurement. With a second measuring unit, which has a light source and a scattered light detector, cell monitoring can be carried out during the cell measurement. For this purpose the receiving unit has an at least partially light-permeable substrate and is arranged between the light source and scattered light detector such that at least a part of the light generated by the light source shines on the receiving unit, is scattered on the test cells and, after leaving the receiving unit through the substrate, impinges on the scattered light detector.
摘要翻译：用于监测测试单元的装置具有用于测试单元的至少一个接收单元和用于单元测量的第一测量单元。利用具有光源和散射光检测器的第二测量单元，可以在电池测量期间进行电池监测。为此目的，接收单元具有至少部分透光的基板，并且布置在光源和散射光检测器之间，使得由光源产生的光的至少一部分照射在接收单元上，散射在在离开接收单元通过基板之后，撞击在散射光检测器上。

2. 发明申请

US20100184062A1 Method for Identifying and Quantifying Organic and Biochemical Substances 审中-公开
标题翻译：识别和定量有机和生化物质的方法
公开(公告)号：US20100184062A1
公开(公告)日：2010-07-22
申请号：US12667583
申请日：2008-07-04
申请人： Doris Steinmüller-Nethl , Anton Köck , Detlef Steinmüller , Kriemhilt Roppert
发明人： Doris Steinmüller-Nethl , Anton Köck , Detlef Steinmüller , Kriemhilt Roppert
IPC分类号： C12Q1/68 , G01N33/53
CPC分类号： C12Q1/6825 , G01N33/5438 , C12Q2565/543 , C12Q2537/162
摘要： The invention relates to a method for identifying organic or biochemical substances and for determining their concentration in a fluid medium using a nanogap sensor that comprises at least two electrodes. The invention is characterized in that: a nanogap sensor) with electrodes of different materials is used, a respective probe molecule is bonded to each surface of the two electrodes of the sensor and the free remainder of the probe molecules have at least one bondable group with specificity for bonding to a sought substance or to an analyte molecule in the fluid medium. The analyte molecule has at least two binding sites and passes selectively out of the fluid medium in which it is contained, binds to the free ends of the probe molecules, forming a bridge with the probe molecule, and modifies the resulting impedance between the electrodes. The concentration of the substance in the fluid medium can be determined as a result of the modification.
摘要翻译：本发明涉及用于鉴别有机或生物化学物质并使用包含至少两个电极的纳米隙传感器来测定其在流体介质中的浓度的方法。本发明的特征在于：使用具有不同材料的电极的纳米隙传感器），将相应的探针分子结合到传感器的两个电极的每个表面，并且探针分子的游离剩余部分具有至少一个可结合的基团，与所寻求的物质或流体介质中的分析物分子结合的特异性。分析物分子具有至少两个结合位点，并且选择性地从其所含的流体介质中流出，与探针分子的自由端结合，与探针分子形成桥，并修改电极之间产生的阻抗。流体介质中物质的浓度可以作为修改的结果来确定。

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