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1. 发明申请

US20160001022A1 NASAL DELIVERY 审中-公开
标题翻译： NASAL交货
公开(公告)号：US20160001022A1
公开(公告)日：2016-01-07
申请号：US14618273
申请日：2015-02-10
申请人： Per Gisle DJUPESLAND , Colin David SHELDRAKE
发明人： Per Gisle DJUPESLAND , Colin David SHELDRAKE
IPC分类号： A61M15/08 , A61M15/00
CPC分类号： A61M15/085 , A61M15/0021 , A61M15/0098 , A61M15/08 , A61M2202/064 , A61M2210/0625
摘要： A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece for fitting to a nostril of a subject, wherein the nosepiece comprises a tip element which includes a delivery aperture from which substance is in use delivered into the nasal cavity, and the tip element is at least in part tapered such as to be inclined to a longitudinal axis of the nosepiece, with the delivery aperture extending both laterally across the tip element and along a longitudinal extent of the tip element; a nozzle through which substance is in use delivered, preferably substantially axially to a longitudinal axis of the nosepiece, to the respective nasal cavity; and a delivery unit for delivering substance through the nozzle of the nosepiece.
摘要翻译：一种用于将物质输送到受试者鼻腔的鼻部输送装置和方法，所述输送装置包括：用于装配到受试者的鼻孔的鼻梁，其中所述鼻梁包括尖端元件，所述尖端元件包括物质为在使用中输送到鼻腔中，并且尖端元件至少部分是锥形的，以便相对于鼻梁的纵向轴线倾斜，其中输送孔横向延伸穿过尖端元件并沿着尖端的纵向延伸元件; 物质被使用的喷嘴，优选地基本上轴向地连接到鼻梁的纵向轴线到相应的鼻腔; 以及用于通过喷嘴的喷嘴输送物质的输送单元。

2. 发明申请

US20120073571A1 NASAL DELIVERY DEVICE 审中-公开
标题翻译： NASAL交付设备
公开(公告)号：US20120073571A1
公开(公告)日：2012-03-29
申请号：US12955546
申请日：2010-11-29
申请人： Per Gisle DJUPESLAND
发明人： Per Gisle DJUPESLAND
IPC分类号： A61M11/00 , A61M15/08
CPC分类号： A61M15/0091 , A61M15/0065 , A61M15/009 , A61M15/0095 , A61M15/0098 , A61M15/08 , A61M2210/0618 , A61M2210/0625
摘要： A breath-actuated nasal delivery device, comprising: a mouthpiece through which a user in use exhales to actuate the delivery device; a nosepiece for fitting to a nostril of the user through which a substance is in use delivered; a substance supply unit actuatable to deliver a dose of a substance through the nosepiece; a loading unit operable to load the substance supply unit with an actuation force; and a release mechanism for enabling actuation of the substance supply unit in response to exhalation by the user through the mouthpiece; wherein the release mechanism comprises a locking unit which is movable: between a locking configuration in which the substance supply unit is locked in a non-actuated position when loaded by the loading unit and a release configuration in which the substance supply unit is actuatable by the loading unit, and a trigger member for releasing the locking unit from the locking configuration to the release configuration in response to exhalation by the user through the mouthpiece and thereby enabling actuation of the substance supply unit.
摘要翻译：一种呼吸致动的鼻腔输送装置，包括：口部，使用者通过所述吸口呼气以致动所述输送装置; 用于装配用户使用物质的鼻孔的鼻梁; 物质供应单元，可致动以通过物镜传送一定剂量的物质; 装载单元，其可操作以用致动力装载物质供应单元; 以及释放机构，用于响应于使用者通过所述嘴件的呼出而使得所述物质供应单元能够致动; 其中所述释放机构包括锁定单元，所述锁定单元可移动：在由所述装载单元加载时所述物质供应单元被锁定在非致动位置的锁定构造和其中所述物质供应单元可被所述装载单元致动的释放构造之间以及触发构件，用于响应于使用者通过接口进行呼出，从而使物质供应单元的致动，将锁定单元从锁定构型释放到释放构造。

3. 发明申请

US20080161771A1 NASAL DELEVERY DEVICES 有权
公开(公告)号：US20080161771A1
公开(公告)日：2008-07-03
申请号：US11963063
申请日：2007-12-21
申请人： Per Gisle DJUPESLAND
发明人： Per Gisle DJUPESLAND
IPC分类号： A61M37/00
CPC分类号： A61M15/08 , A61B5/085 , A61B5/097 , A61B5/415 , A61B5/4839 , A61M11/001 , A61M11/005 , A61M11/006 , A61M11/007 , A61M11/02 , A61M15/002 , A61M15/0021 , A61M15/0065 , A61M15/009 , A61M15/0091 , A61M15/0098 , A61M2016/0021 , A61M2202/04 , A61M2202/064 , A61M2205/071 , A61M2205/073 , A61M2205/13 , A61M2210/0668 , A61M2230/43
摘要： An exhalation breath-actuated nasal deliver device for and a method of delivering a substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece for fitting to a nostril of a subject; a mouthpiece through which the subject in use exhales; and delivery unit, as one of a mechanical delivery pump or a nebulizer, for delivering a substance to the nosepiece; and an actuation mechanism for actuating the delivery unit in response to oral exhalation through the mouthpiece, and preferably when at least one or both of the pressure at or the flow rate through the nosepiece exceeds a predetermined threshold.
摘要翻译：一种呼气呼吸致动鼻输送装置和一种将物质输送到受试者的鼻腔的方法，所述输送装置包括：鼻梁，用于装配到受试者的鼻孔; 用于呼吸的受试者的喉舌; 和作为机械输送泵或雾化器之一的输送单元，用于将物质输送到喷嘴; 以及致动机构，用于响应于通过接口管的口腔呼气来致动传送单元，并且优选地当通过喷嘴的压力或流速中的至少一个或两个超过预定阈值时。

4. 发明申请

US20080163874A1 NASAL DELIVERY DEVICE 审中-公开
标题翻译： NASAL交付设备
公开(公告)号：US20080163874A1
公开(公告)日：2008-07-10
申请号：US11964766
申请日：2007-12-27
申请人： Per Gisle DJUPESLAND
发明人： Per Gisle DJUPESLAND
IPC分类号： A61M15/08
CPC分类号： A61M15/0091 , A61M15/0065 , A61M15/009 , A61M15/0095 , A61M15/0098 , A61M15/08 , A61M2210/0618 , A61M2210/0625
摘要： A breath-actuated nasal delivery device, comprising: a mouthpiece through which a user in use exhales to actuate the delivery device; a nosepiece for fitting to a nostril of the user through which a substance is in use delivered; a substance supply unit actuatable to deliver a dose of a substance through the nosepiece; a loading unit operable to load the substance supply unit with an actuation force; and a release mechanism for enabling actuation of the substance supply unit in response to exhalation by the user through the mouthpiece; wherein the release mechanism comprises a locking unit which is movable: between a locking configuration in which the substance supply unit is locked in a non-actuated position when loaded by the loading unit and a release configuration in which the substance supply unit is actuatable by the loading unit, and a trigger member for releasing the locking unit from the locking configuration to the release configuration in response to exhalation by the user through the mouthpiece and thereby enabling actuation of the substance supply unit.
摘要翻译：一种呼吸致动的鼻腔输送装置，包括：口部，使用者通过所述吸口呼气以致动所述输送装置; 用于装配用户使用物质的鼻孔的鼻梁; 物质供应单元，可致动以通过物镜传送一定剂量的物质; 装载单元，其可操作以用致动力装载物质供应单元; 以及释放机构，用于响应于使用者通过所述嘴件的呼出而使得所述物质供应单元能够致动; 其中所述释放机构包括锁定单元，所述锁定单元可移动：在由所述装载单元加载时所述物质供应单元被锁定在非致动位置的锁定构造和其中所述物质供应单元可被所述装载单元致动的释放构造之间以及触发构件，用于响应于使用者通过接口进行呼出，从而使物质供应单元的致动，将锁定单元从锁定构型释放到释放构造。

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