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    • 2. 发明授权
    • Plugged tip delivery for marker placement
    • 用于标记放置的插头提示
    • US07651505B2
    • 2010-01-26
    • US10174401
    • 2002-06-17
    • Paul LubockJason H. SafabashMartin ShabazJohn Merritt
    • Paul LubockJason H. SafabashMartin ShabazJohn Merritt
    • A61B17/00
    • A61M37/0069A61B90/39A61B2090/3908A61B2090/3925A61B2090/3987
    • The invention provides marker delivery devices, assemblies, and methods. Assemblies embodying features of the invention include marker delivery devices having a delivery tube with an orifice, markers, and a plug releasably disposed in the tube occluding the orifice. The plug prevents markers from passing through the orifice before the marker is to be placed at a desired location within a patient's body, prevents ingress of tissue into the bore of the tube, and allows markers to pass out of the orifice when marker delivery is desired. Guidance of a delivery tube to a desired location within a patient's body may include the use of an imaging device, with or without the use of a guide cannula. The plug may itself serve as a marker, and may be the sole marker. Markers may be detectable by ultrasound, X-ray, magnetic resonance imaging, and other imaging devices, and may include bioactive elements.
    • 本发明提供标记递送装置,组件和方法。 体现本发明特征的组件包括具有输送管的标记输送装置,该输送管具有孔口,标记物和可释放地设置在阻塞孔口的管中的塞子。 在将标记物放置在患者体内的期望位置之前,塞子防止标记物通过孔口,防止组织进入管孔中,并且当需要标记物递送时允许标记物从孔中流出孔口 。 将输送管引导到患者体内的期望位置可以包括在使用或不使用引导套管的情况下使用成像装置。 插头本身可以用作标记,并且可以是唯一的标记。 标记可以通过超声,X射线,磁共振成像和其他成像装置检测,并且可以包括生物活性元件。
    • 4. 发明授权
    • Plugged tip delivery tube for marker placement
    • 用于标记放置的堵塞尖端输送管
    • US08177792B2
    • 2012-05-15
    • US12592020
    • 2009-11-18
    • Paul LubockJason H. SafabashMartin ShabazJohn Merritt
    • Paul LubockJason H. SafabashMartin ShabazJohn Merritt
    • A61B17/00
    • A61M37/0069A61B90/39A61B2090/3908A61B2090/3925A61B2090/3987
    • An intracorporeal marker delivery device includes a delivery tube which has a tapered, tissue penetrating distal tip, an inclined discharge orifice in the tapered distal tip and an inner bore extending to the orifice. A plurality of remotely detectable markers, which are formed at least in part of bioresorbable material, are slidably disposed within the inner bore. A plug having an inclined exposed surface, which is formed at least in part of bioresorbable material, is releasably secured within the inner bore of the delivery tube distal to the plurality of remotely detectable markers disposed therein to retain the plurality of remotely detectable markers within the inner bore. The plug is disposed at least in part within the inclined discharge orifice. A plunger is slidably disposed within the inner bore proximal to the plurality of remotely detectable markers.
    • 体内标记递送装置包括输送管,该输送管具有锥形的组织穿透远侧末端,锥形远端中的倾斜排出孔和延伸到孔的内孔。 形成至少部分生物可再吸收材料的多个可远程检测的标记物可滑动地设置在内孔内。 具有至少部分生物可再吸收材料形成的倾斜暴露表面的塞子可释放地固定在输送管的内孔内,远离设置在其中的多个可远程检测的标记,以将多个可远程检测的标记物保持在 内孔。 塞子至少部分地设置在倾斜的排放口内。 柱塞可滑动地设置在靠近多个可远程检测的标记的内孔内。
    • 5. 发明申请
    • Plugged tip delivery tube for marker placement
    • 用于标记放置的堵塞尖端输送管
    • US20100094169A1
    • 2010-04-15
    • US12592020
    • 2009-11-18
    • Paul LubockJason H. SafabashMartin ShabazJohn Merritt
    • Paul LubockJason H. SafabashMartin ShabazJohn Merritt
    • A61B10/00A61B17/00
    • A61M37/0069A61B90/39A61B2090/3908A61B2090/3925A61B2090/3987
    • The invention provides marker delivery devices, assemblies, and methods. Assemblies embodying features of the invention include marker delivery devices having a delivery tube with an orifice, markers, and a plug releasably disposed in the tube occluding the orifice. The plug prevents markers from passing through the orifice before the marker is to be placed at a desired location within a patient's body, prevents ingress of tissue into the bore of the tube, and allows markers to pass out of the orifice when marker delivery is desired. Guidance of a delivery tube to a desired location within a patient's body may include the use of an imaging device, with or without the use of a guide cannula. The plug may itself serve as a marker, and may be the sole marker. Markers may be detectable by ultrasound, X-ray, magnetic resonance imaging, and other imaging devices, and may include bioactive elements.
    • 本发明提供标记递送装置,组件和方法。 体现本发明特征的组件包括具有输送管的标记输送装置,该输送管具有孔口,标记物和可释放地设置在阻塞孔口的管中的塞子。 在将标记物放置在患者体内的期望位置之前,塞子防止标记物通过孔口,防止组织进入管孔中,并且当需要标记递送时允许标记物从孔口中流出孔口 。 将输送管引导到患者体内的期望位置可以包括在使用或不使用引导套管的情况下使用成像装置。 插头本身可以用作标记,并且可以是唯一的标记。 标记可以通过超声,X射线,磁共振成像和其他成像装置检测,并且可以包括生物活性元件。
    • 10. 发明申请
    • Biopsy device with selectable tissue receiving aperture orientation and site illumination
    • 活组织检查装置,可选择组织接收孔径取向和局部照明
    • US20050065453A1
    • 2005-03-24
    • US10911106
    • 2004-08-03
    • Martin ShabazRichard QuickFrank LouwPaul LubockJason Safabash
    • Martin ShabazRichard QuickFrank LouwPaul LubockJason Safabash
    • A61B10/00A61B10/02A61B17/00A61B17/32A61B17/34
    • A61B10/0275A61B10/0266A61B10/0283A61B17/32002A61B17/3417A61B90/30A61B2010/0208A61B2010/0225A61B2017/00473A61B2017/00486A61B2017/3405A61B2090/3908A61B2090/3987
    • The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.
    • 本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。 该装置包括具有细长管状部分的探针部件,穿透远侧末端和在远端顶端的管状部分的远端中的组织接收孔,以及组织切割构件,其可滑动地设置在探针构件内以切割 组织样本通过向组织切割构件的内腔施加真空而通过孔被拉入装置的内部。 该装置还具有驱动器部件,探针组件可释放地固定到该部件上。 驱动器具有用于调节管状部分的方向并因此调节其中的孔的驱动构件和一个或多个驱动构件,用于移动管状区段内的组织切割构件以将组织样本从延伸到管状部分内部的组织切断 通过光圈。 赋予组织切割器的运动至少是纵向的,并且优选也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。