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1. 发明申请

US20130184418A1 PREPARATION OF A MOLECULAR RECOGNITION ELEMENT 有权
标题翻译：分子识别元素的制备
公开(公告)号：US20130184418A1
公开(公告)日：2013-07-18
申请号：US13823304
申请日：2011-09-09
申请人： Patrick Shahgaldian , Alessandro Cumbo , Philippe Corvini
发明人： Patrick Shahgaldian , Alessandro Cumbo , Philippe Corvini
IPC分类号： C08G77/18
CPC分类号： C08G77/18 , B01J20/268 , G01N33/54313 , G01N33/54353 , G01N2600/00
摘要： A method for preparation of a molecular recognition element comprising the steps of binding a template to a surface of a carrier material, providing a recognition material to the surface of the carrier material, initiating polymerization of the recognition material on the surface of the carrier material, stopping the polymerization of the recognition material on the surface of the carrier material, and releasing the template from the surface of the carrier material and the polymerized recognition material. The method is characterized as an aim size of individual imprints is predefined, and the polymerization of the recognition material on the surface of the carrier material is stopped when a size of individual imprints of the polymerized recognition material essentially equals the predefined aim size. This method is readily applicable for preparation of a molecular recognition element useful as a drug, catalyst, competitive affinity ligand inhibitor, competitor, agonist, antagonist or diagnostic agent.
摘要翻译：一种制备分子识别元件的方法，包括以下步骤：将模板结合到载体材料的表面，向载体材料的表面提供识别材料，引发识别材料在载体材料表面上的聚合，停止载体材料表面上的识别材料的聚合，并从载体材料和聚合识别材料的表面释放模板。该方法的特征在于预定义个体印记的目标尺寸，并且当聚合识别材料的单独印记的尺寸基本上等于预定义的目标尺寸时，停止载体材料表面上识别材料的聚合。该方法容易适用于制备可用作药物，催化剂，竞争性亲和配体抑制剂，竞争剂，激动剂，拮抗剂或诊断剂的分子识别元件。

2. 发明授权

US08871837B2 Preparation of a molecular recognition element 有权
标题翻译：分子识别元件的制备
公开(公告)号：US08871837B2
公开(公告)日：2014-10-28
申请号：US13823304
申请日：2011-09-09
申请人： Patrick Shahgaldian , Alessandro Cumbo , Philippe Corvini
发明人： Patrick Shahgaldian , Alessandro Cumbo , Philippe Corvini
IPC分类号： C08K9/06 , B01J20/26 , G01N33/543 , C08G77/18
CPC分类号： C08G77/18 , B01J20/268 , G01N33/54313 , G01N33/54353 , G01N2600/00
摘要： A method for preparation of a molecular recognition element comprising the steps of binding a template to a surface of a carrier material, providing a recognition material to the surface of the carrier material, initiating polymerization of the recognition material on the surface of the carrier material, stopping the polymerization of the recognition material on the surface of the carrier material, and releasing the template from the surface of the carrier material and the polymerized recognition material. The method is characterized as an aim size of individual imprints is predefined, and the polymerization of the recognition material on the surface of the carrier material is stopped when a size of individual imprints of the polymerized recognition material essentially equals the predefined aim size. This method is readily applicable for preparation of a molecular recognition element useful as a drug, catalyst, competitive affinity ligand inhibitor, competitor, agonist, antagonist or diagnostic agent.
摘要翻译：一种制备分子识别元件的方法，包括以下步骤：将模板结合到载体材料的表面，向载体材料的表面提供识别材料，引发识别材料在载体材料表面上的聚合，停止载体材料表面上的识别材料的聚合，并从载体材料和聚合识别材料的表面释放模板。该方法的特征在于预定义个体印记的目标尺寸，并且当聚合识别材料的单独印记的尺寸基本上等于预定义的目标尺寸时，停止载体材料表面上识别材料的聚合。该方法容易适用于制备可用作药物，催化剂，竞争性亲和配体抑制剂，竞争剂，激动剂，拮抗剂或诊断剂的分子识别元件。

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