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1. 发明申请

US20130165807A1 SYSTEM FOR THE AUTOMATIC DETECTION OF RESPIRATORY DISEASES AND FOR THE PREDICTION OF FUTURE ACUTE AIRWAY INSTABILITIES 有权
标题翻译：呼吸系统疾病自动检测系统及预测未来急性空气不稳定
公开(公告)号：US20130165807A1
公开(公告)日：2013-06-27
申请号：US13822098
申请日：2011-09-09
申请人： Alessandro Gobbi , Pasquale Pio Pompilio , Raffaele Dellaca' , Antonio Pedotti
发明人： Alessandro Gobbi , Pasquale Pio Pompilio , Raffaele Dellaca' , Antonio Pedotti
IPC分类号： A61B5/085 , A61B5/00
CPC分类号： A61B5/085 , A61B5/087 , A61B5/4842 , A61B5/7275
摘要： A system for automatically predicting acute airway events in patients, comprising: a device for measuring the respiratory impedance of a human subject during a plurality of respiratory cycles of said human subject; said respiratory impedance comprising a real part and an imaginary part; said device measuring said respiratory impedance two times per day to provide a plurality of measurements; means for calculating the relative variation of said plurality of measurements; means for evaluating the probability of respiratory pathology presence in the subject under examination when the value of the imaginary part of said impedance is greater than 35%; means for predicting a relapse in the patent under examination within an established future time window, once the presence of the pathology has been ascertained, if the variation coefficient of the real part of said impedance is greater than 0.4.
摘要翻译：一种用于自动预测患者急性呼吸道事件的系统，包括：用于在所述人类受试者的多个呼吸循环期间测量人类受试者的呼吸阻抗的装置; 所述呼吸阻抗包括实部和虚部; 所述装置每天测量两次呼吸阻力以提供多个测量; 用于计算所述多个测量的相对变化的装置; 当所述阻抗的虚部的值大于35％时，用于评估在检查对象中呼吸道病理学存在概率的方法; 如果所述阻抗的实部的变化系数大于0.4，则在确定的病理学存在之后，在已建立的未来时间窗口内预测在检查中的专利复发的手段。

2. 发明申请

US20130150747A1 SYSTEM AND METHOD FOR MEASURING THE MECHANICAL IMPEDANCE OF THE RESPIRATORY SYSTEM 审中-公开
标题翻译：用于测量呼吸系统的机械阻抗的系统和方法
公开(公告)号：US20130150747A1
公开(公告)日：2013-06-13
申请号：US13812180
申请日：2011-05-17
申请人： Pasquale Pio Pompilio , Alessandro Gobbi , Raffaele Dellaca' , Antonio Pedotti
发明人： Pasquale Pio Pompilio , Alessandro Gobbi , Raffaele Dellaca' , Antonio Pedotti
IPC分类号： A61B5/085
摘要： A system for measuring the mechanical impedance of a patient's respiratory system during spontaneous respiratory activity, characterised by comprising a fan; a motor which operates said fan; said motor and said fan being positioned within a cavity; said cavity comprising an initial end and a final end, both providing access to the outside; said cavity presenting an impedance between said initial and said final end of less than 1 cm H2O/L/s; said fan withdrawing air from said final end and providing pressure variations of small amplitude and of frequency >2 Hz to said initial end; said initial end comprising air pressure and air flow measurement means and a connection directly connected to the airway opening.
摘要翻译：一种用于在自发呼吸活动期间测量患者呼吸系统的机械阻抗的系统，其特征在于包括风扇; 操作所述风扇的电动机; 所述马达和所述风扇位于空腔内; 所述腔包括初始端和最终端，两者都提供通向外部的通路; 所述空腔在所述初始和所述最终端之间呈现小于1cm H 2 O / L / s的阻抗; 所述风扇从所述最终端抽出空气，并向所述初始端提供小振幅和频率> 2Hz的压力变化; 所述初始端包括空气压力和空气流量测量装置以及直接连接到气道开口的连接。

3. 发明申请

US20100147305A1 System and Method for the Automatic Detection of the Expiratory Flow Limitation 有权
标题翻译：用于自动检测呼气流量限制的系统和方法
公开(公告)号：US20100147305A1
公开(公告)日：2010-06-17
申请号：US12640880
申请日：2009-12-17
申请人： Raffaele Dellaca' , Andrea Aliverti , Antonio Pedotti
发明人： Raffaele Dellaca' , Andrea Aliverti , Antonio Pedotti
IPC分类号： A61B5/085 , A61M16/00
CPC分类号： A61B5/085
摘要： The present invention refers to a system and a method for the automatic detection of the expiratory flow limitation of a subject. In an embodiment thereof the system for the automatic detection of expiratory flow limitation of a subject comprises determining the respiratory impedance of the subject comprising an imaginary component and, eventually, of a real part or, at least, by applying a forcing signal with one or more spectral components to the airway opening of a subject combined with measuring time courses of pressure and flow at the airway opening; determining at least one index linked to respiratory impedance or pressure and flow time courses; indicating the positioning of at least one index in relation to a preset threshold value.
摘要翻译：本发明涉及一种用于自动检测受试者的呼气流量限制的系统和方法。在其一个实施例中，用于自主检测受试者的呼气流量限制的系统包括确定受试者的呼吸阻抗，包括虚部，最终确定实部，或者至少通过将强迫信号与一个或一个对象的气道开口的更多的光谱分量结合测量气道开口处的压力和流量的时间过程; 确定与呼吸阻抗或压力和流动时间过程相关联的至少一个指标; 指示相对于预设阈值定位至少一个索引。

4. 发明申请

US20050178385A1 System and method for the automatic detection of the expiratory flow limitation 有权
标题翻译：用于自动检测呼气流量限制的系统和方法
公开(公告)号：US20050178385A1
公开(公告)日：2005-08-18
申请号：US11002368
申请日：2004-12-02
申请人： Raffaele Dellaca' , Andrea Aliverti , Antonio Pedotti
发明人： Raffaele Dellaca' , Andrea Aliverti , Antonio Pedotti
IPC分类号： A61B5/085 , A62B7/00 , A61M16/00
CPC分类号： A61B5/085
摘要： The present invention refers to a system and a method for the automatic detection of the expiratory flow limitation of a subject. In an embodiment thereof the system for the automatic detection of expiratory flow limitation of a subject comprises: means for determining the respiratory impedance of said subject composes of an imaginary component and, eventually, of a real part or, at least means to apply a forcing signal with one or more spectral components to the airway opening of a subject combined with means to measure time courses of pressure and flow at the airway opening; means for determining at least one index linked to said respiratory impedance or pressure and flow time courses; means for indicating the positioning of said at least one index in relation to a preset threshold value.
摘要翻译：本发明涉及一种用于自动检测受试者的呼气流量限制的系统和方法。在其一个实施例中，用于自主检测受试者的呼气流量限制的系统包括：用于确定所述受试者的呼吸阻抗的装置构成虚构部分，最终由实部组成的装置，或至少施加强制的装置信号，其具有一个或多个频谱分量到对象的气道开口，以及测量气道开口处的压力和流量的时间进程的装置; 用于确定与所述呼吸阻抗或压力和流动时间过程相关联的至少一个指标的装置; 用于指示所述至少一个索引相对于预设阈值的定位的装置。

5. 发明授权

US07325545B2 System and method for the automatic detection of the expiratory flow limitation 有权
标题翻译：用于自动检测呼气流量限制的系统和方法
公开(公告)号：US07325545B2
公开(公告)日：2008-02-05
申请号：US11002368
申请日：2004-12-02
申请人： Raffaele Dellaca' , Andrea Aliverti , Antonio Pedotti
发明人： Raffaele Dellaca' , Andrea Aliverti , Antonio Pedotti
IPC分类号： A61M16/00 , A61M15/00 , A61B19/00 , A61B5/08
CPC分类号： A61B5/085
摘要： The present invention refers to a system and a method for the automatic detection of the expiratory flow limitation of a subject. In an embodiment thereof the system for the automatic detection of expiratory flow limitation of a subject comprises determining the respiratory impedance of the subject comprising an imaginary component and, eventually, of a real part or, at least, by applying a forcing signal with one or more spectral components to the airway opening of a subject combined with measuring time courses of pressure and flow at the airway opening; determining at least one index linked to respiratory impedance or pressure and flow time courses; indicating the positioning of at least one index in relation to a preset threshold value.
摘要翻译：本发明涉及一种用于自动检测受试者的呼气流量限制的系统和方法。在其一个实施例中，用于自主检测受试者的呼气流量限制的系统包括确定受试者的呼吸阻抗，包括虚部，最终确定实部，或者至少通过将强迫信号与一个或一个对象的气道开口的更多的光谱分量结合测量气道开口处的压力和流量的时间过程; 确定与呼吸阻抗或压力和流动时间过程相关联的至少一个指标; 指示相对于预设阈值定位至少一个索引。

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