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1. 发明公开

US20240075282A1 BIOSTIMULATOR HAVING PIVOTABLE ELECTRODE 审中-公开
公开(公告)号：US20240075282A1
公开(公告)日：2024-03-07
申请号：US18239059
申请日：2023-08-28
申请人： Pacesetter, Inc.
发明人： Steve Chantasirivisal , Keith Victorine , Christian Medina , Zoltan Somogyi , Daniel Kwon , Xiagqun Shawn Chen
IPC分类号： A61N1/05
CPC分类号： A61N1/0563 , A61N1/057 , A61N2001/058
摘要： A biostimulator and a biostimulator system for septal pacing, is described. The biostimulator includes a joint to allow an electrode to pivot relative to a housing. The housing contains electrical circuitry that is electrically connected to the pacing electrode. The joint allows the pacing electrode to affix to target tissue of an interventricular septal wall of a heart when the housing is pivoted toward an apex of the heart. Other embodiments are also described and claimed.

2. 发明申请

US20210031028A1 SCREW-IN PERICARDIAL LEADS AND SYSTEMS FOR DELIVERING SCREW-IN PERICARDIAL LEADS 有权
公开(公告)号：US20210031028A1
公开(公告)日：2021-02-04
申请号：US17069102
申请日：2020-10-13
申请人： Pacesetter, Inc.
发明人： Gene A. Bornzin , Devan Hughes , Keith Victorine , Zoltan Somogyi , Matthew Nojoomi , Ekaterina Tkatchouk , Xiaoyi Min
IPC分类号： A61N1/05 , A61N1/39
摘要： Disclosed herein is a screw-in lead implantable in the pericardium of a patient heart and a system for delivering such leads to an implantation location. The leads include a helical tip electrode and a curvate body including a defibrillator coil with improved contact between the defibrillator coil and the patient heart. The delivery system includes a delivery catheter and lead receiving sheath disposed within the catheter. A fixation tine is disposed on one of the delivery catheter and the lead receiving sheath such that the delivery system may be anchored into the pericardium during fixation of the screw-in lead. In certain implementations, an implantable sleeve receives the leads to bias the defibrillator coil against the patient heart.

3. 发明授权

US10292621B2 Systems and methods for retrieving an implantable device 有权
公开(公告)号：US10292621B2
公开(公告)日：2019-05-21
申请号：US15050896
申请日：2016-02-23
申请人： PACESETTER, INC.
发明人： Gene A. Bornzin , Didier Theret , Zoltan Somogyi
IPC分类号： A61N1/00 , A61B5/06 , A61B5/00 , A61B5/04 , A61B5/042 , A61B90/00
摘要： The present disclosure provides systems and methods for retrieving an implantable device. An implantable device includes a casing, and a marker coupled to the casing, wherein the marker includes a detectable material encased in a biocompatible material, and wherein the marker facilitates accurately locating and retrieving the implantable device after implantation in a patient.

4. 发明授权

US09878151B2 Multi-piece dual-chamber leadless intra-cardiac medical device and method of implanting same 有权
公开(公告)号：US09878151B2
公开(公告)日：2018-01-30
申请号：US14676320
申请日：2015-04-01
申请人： PACESETTER, INC.
发明人： Gene A. Bornzin , John W. Poore , Zoltan Somogyi , Xiaoyi Min
IPC分类号： A61N1/00 , A61N1/05 , A61N1/375 , A61N1/372 , A61N1/365
CPC分类号： A61N1/059 , A61N1/0573 , A61N1/36521 , A61N1/37288 , A61N1/3756
摘要： A leadless intra-cardiac medical device (LIMD) includes an electrode assembly configured to be anchored within a first wall portion of a first chamber of a heart. The electrode assembly includes an electrode main body having a first securing helix, an electrode wire segment extending from the body, and a first segment-terminating contact positioned on the electrode wire segment. The device further includes a housing assembly configured to be anchored within a second wall portion of a second chamber of the heart. The housing assembly includes a body having a second securing helix, a housing wire segment extending from the body, and a second segment-terminating contact positioned on the housing wire segment. The device also includes a connector block that electrically connects the electrode wire segment to the housing wire segment by retaining the first and second segment-terminating contacts.

5. 发明申请

US20170065369A1 SYSTEMS AND METHODS FOR RETRIEVING AN IMPLANTABLE DEVICE 审中-公开
标题翻译：用于检索可植入设备的系统和方法
公开(公告)号：US20170065369A1
公开(公告)日：2017-03-09
申请号：US15050896
申请日：2016-02-23
申请人： PACESETTER, INC.
发明人： Gene A. Bornzin , Didier Theret , Zoltan Somogyi
IPC分类号： A61B90/90 , A61B5/042 , A61B5/06 , A61B90/00
CPC分类号： A61B5/062 , A61B5/042 , A61B5/686 , A61B2090/3954 , A61B2562/0223
摘要： The present disclosure provides systems and methods for retrieving an implantable device. An implantable device includes a casing, and a marker coupled to the casing, wherein the marker includes a detectable material encased in a biocompatible material, and wherein the marker facilitates accurately locating and retrieving the implantable device after implantation in a patient.
摘要翻译：本公开提供了用于检索可植入装置的系统和方法。可植入装置包括壳体和联接到壳体的标记，其中所述标记包括包封在生物相容性材料中的可检测材料，并且其中所述标记器有助于在植入患者体内之后准确地定位和取回所述可植入装置。

6. 发明申请

US20160158562A1 SYSTEMS AND METHODS FOR NEUROSTIMULATION OF A PERIPHERAL NERVE 审中-公开
标题翻译：用于外周神经神经元的系统和方法
公开(公告)号：US20160158562A1
公开(公告)日：2016-06-09
申请号：US14927328
申请日：2015-10-29
申请人： PACESETTER, INC.
发明人： Gene A. Bornzin , Timothy A. Fayram , Stuart Rosenberg , Zoltan Somogyi , John W. Poore
IPC分类号： A61N1/372 , A61N1/36 , A61N1/05
CPC分类号： A61N1/37223 , A61N1/0526 , A61N1/0551 , A61N1/36075
摘要： Systems and methods are provided for neurostimulation (NS) of peripheral nerves and/or associated ganglion. The systems and methods create a magnetic field from an elongated transmission coil of an external stimulator and expose an elongated receiver coil of a magnetic driver to the magnetic field. The systems and methods generate at the magnetic driver a pulse forming a stimulation waveform in response to the magnetic field. The systems and methods deliver the stimulation waveform to a target peripheral nerve through an electrode from the magnetic driver.
摘要翻译：为周围神经和/或相关神经节的神经刺激（NS）提供系统和方法。系统和方法从外部刺激器的细长传输线圈产生磁场，并将磁驱动器的细长接收线圈暴露于磁场。系统和方法在磁驱动器处产生响应于磁场形成刺激波形的脉冲。系统和方法通过来自磁驱动器的电极将刺激波形传送到目标周围神经。

7. 发明申请

US20160045723A1 IMPLANTABLE NEUROSTIMULATION SYSTEMS AND METHODS THEREOF 审中-公开
标题翻译：可植入神经系统及其方法
公开(公告)号：US20160045723A1
公开(公告)日：2016-02-18
申请号：US14462329
申请日：2014-08-18
申请人： PACESETTER, INC.
发明人： Gene A. Bornzin , Zoltan Somogyi , Kevin Wilson
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/0534 , A61N1/0539 , A61N1/36067 , A61N1/36082 , A61N1/36125 , A61N1/375
摘要： The present disclosure provides neurostimulation methods and system for deep brain stimulation. A neurostimulation apparatus includes a plug configured to be mounted to a burr hole formed in a skull of a subject, a plurality of cable conductors configured to be coupled to the plug, and a lead configured to be coupled to the plurality of cable conductors, the lead comprising at least one electrode configured to apply stimulation to the subject, wherein the plug is configured to generate and supply electrical stimulation pulses to the lead through the plurality of cable conductors.
摘要翻译：本公开提供了用于深部脑刺激的神经刺激方法和系统。神经刺激装置包括被配置为安装到形成在被检体的颅骨中的毛刺孔的栓塞，被配置为联接到栓塞的多个电缆导体以及被配置为联接到多个电缆导体的引线，引线包括至少一个被配置为对受试者施加刺激的电极，其中所述插头被配置为通过所述多个电缆导体产生并向所述引线提供电刺激脉冲。

8. 发明申请

US20150142010A1 NEUROSTIMULATION LEADS HAVING TWO-DIMENSIONAL ARRAYS 审中-公开
标题翻译：具有二维阵列的神经细胞引导线
公开(公告)号：US20150142010A1
公开(公告)日：2015-05-21
申请号：US14086686
申请日：2013-11-21
申请人： PACESETTER, INC.
发明人： Xiaoyi Min , Gene A. Bornzin , Zoltan Somogyi , Melanie Goodman Keiser , Riddhi Shah , Edith Arnold
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61N1/36071
摘要： A neurostimulation lead including an elongated lead body having a distal end and a proximal base. The lead body may have an elastic property such that the lead body is capable of flexing between different geometries. The lead may also include electrodes positioned along the lead body. The lead body may be configured to be straightened into a substantially linear geometry for delivering the lead body into an epidural space and may be biased such that the lead body is configured to have a wave-like geometry when disposed within the epidural space. The lead body may form first and second lateral segments that are joined by a corresponding linking portion when in the wave-like geometry.
摘要翻译：神经刺激引线，包括具有远端和近端基部的细长引线体。引线体可以具有弹性特性，使得引线体能够在不同几何形状之间弯曲。引线还可以包括沿引线体定位的电极。引线体可以被构造成被拉直成基本上线性的几何形状，用于将引线体输送到硬膜外腔中并且可以被偏置，使得引线主体被配置为当设置在硬膜外腔内时具有波状几何形状。引线体可以形成第一和第二横向段，当波浪状几何形状时，引线体由相应的连接部分连接。

9. 发明申请

US20140288576A1 METHOD OF IMPLANTING A UNITARY DUAL-CHAMBER LEADLESS INTRA-CARDIAC MEDICAL DEVICE 审中-公开
标题翻译：单位双室无胸膜内科医疗装置的方法
公开(公告)号：US20140288576A1
公开(公告)日：2014-09-25
申请号：US14298781
申请日：2014-06-06
申请人： PACESETTER, INC.
发明人： Gene A. Bornzin , John W. Poore , Zoltan Somogyi
IPC分类号： A61N1/05
CPC分类号： A61N1/059 , A61B17/3468 , A61N1/0573 , A61N1/37205 , A61N1/3756 , A61N1/3962
摘要： A method of implanting a leadless intra-cardiac medical device. An introducer assembly is introduced into one of an inferior vena cava or a superior vena cava of a heart and maneuvered into a first chamber of the heart. A housing is pushed out of a sheath of the introducer toward a first implant location within the first chamber, and the housing is anchored to the first implant location. The sheath is moved away from the anchored housing, and an electrode is urged to a distal end of the sheath due to the pushing, anchoring, and moving. The sheath is maneuvered to a second chamber of the heart, and the electrode is forced into a second implant location with the second chamber. The electrode is anchored to the second implant location. The sheath is moved away from the electrode after the anchoring, and the sheath is removed from the heart.
摘要翻译：一种植入无引线心脏内心脏医疗器械的方法。导引器组件被引入心脏的下腔静脉或上腔静脉中的一个并且被操纵到心脏的第一腔室中。将外壳从导引器的护套推出到第一腔室内的第一植入位置，并且壳体被锚定到第一植入位置。护套从锚定的壳体移开，并且由于推动，锚定和移动，电极被推动到护套的远端。护套被操纵到心脏的第二腔室，并且电极被强制进入具有第二腔室的第二植入位置。电极锚固到第二植入位置。锚固后护套从电极移开，护套从心脏移除。

10. 发明申请

US20230062838A1 SYSTEMS AND METHODS FOR IMPLANTING A MEDICAL DEVICE USING AN ACTIVE GUIDEWIRE 有权
公开(公告)号：US20230062838A1
公开(公告)日：2023-03-02
申请号：US17978262
申请日：2022-11-01
申请人： Pacesetter, Inc.
发明人： Alexander R. Bornzin , Gene A. Bornzin , Zoltan Somogyi , Wenwen Li , Xiaoyi Min
IPC分类号： A61N1/37 , A61N1/05
摘要： Systems and methods for implanting a lead. The system includes an active guidewire having proximal and distal ends. The distal end includes a guidewire anchor that is configured to be attached to a target SOL. The active guidewire is configured to be utilized to electrically map the target SOI by at least one of delivering stimulation energy through the active guide wire to the target SOI or sensing an evoked response at the target SOI from the guidewire. The system also includes a lead having a lead body with proximal and distal ends and with a lumen extending between the proximal and distal ends. The distal end of the lead body is configured to receive the proximal end of the active guidewire. The lumen is configured to permit the lead body to be advanced over the active guidewire.

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