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1. 发明申请

US20070185057A1 Novel Indanone Compounds 审中-公开
标题翻译：新型茚满酮化合物
公开(公告)号：US20070185057A1
公开(公告)日：2007-08-09
申请号：US11685533
申请日：2007-03-13
申请人： Oskar Koch , Erick Dilk , Roland Langner , William Johncock
发明人： Oskar Koch , Erick Dilk , Roland Langner , William Johncock
IPC分类号： A61K31/695 , A61K31/22 , A61K31/12 , C07F7/04 , C07C49/395
CPC分类号： C07D319/14 , A61K8/40 , A61K8/498 , A61K8/585 , A61Q17/04 , C07C255/40 , C07C2601/14 , C07C2602/08 , C07F7/0838
摘要： Novel indanylidene compounds can be used as UV-A filters in cosmetic compositions for protecting skin and hair and for technical applications.
摘要翻译：新颖的茚满基化合物可用作化妆品组合物中的UV-A过滤器，用于保护皮肤和毛发以及技术应用。

2. 发明授权

US07208142B2 Indanylidene compounds 失效
标题翻译：亚茚基化合物
公开(公告)号：US07208142B2
公开(公告)日：2007-04-24
申请号：US10008044
申请日：2001-11-08
申请人： Oskar Koch , Erich Dilk , Roland Langner , William Johncock
发明人： Oskar Koch , Erich Dilk , Roland Langner , William Johncock
IPC分类号： A61K8/00 , A61K8/18 , A61Q17/04 , F21V9/06 , C07D319/00
CPC分类号： C07D319/14 , A61K8/40 , A61K8/498 , A61K8/585 , A61Q17/04 , C07C255/40 , C07C2601/14 , C07C2602/08 , C07F7/0838
摘要： Novel indanylidene compounds can be used as UV-A filters in cosmetic compositions for protecting skin and hair and for technical applications.
摘要翻译：新颖的茚满基化合物可用作化妆品组合物中的UV-A过滤器，用于保护皮肤和毛发以及技术应用。

3. 发明授权

US06258963B1 Benzylidene-&ggr;-butyrolactones, process for their preparation and their use as UV absorber 有权
标题翻译：亚苄基-γ-丁内酯，其制备方法及其作为UV吸收剂的用途
公开(公告)号：US06258963B1
公开(公告)日：2001-07-10
申请号：US09458135
申请日：1999-12-09
申请人： Oskar Koch , William Johncock , Roland Langner
发明人： Oskar Koch , William Johncock , Roland Langner
IPC分类号： C07D30733
CPC分类号： C07D307/58 , A61K8/4973 , A61Q5/02 , A61Q17/04
摘要： The invention relates to modified benzylidene-&ggr;-butyrolactones, to a process for their preparation and to the use as UV absorber, for example in pharmaceutical and cosmetic compositions, sunscreens, daycare and haircare products, for improving industrial products, such as paints, surface coatings, plastics, textiles, packaging materials and rubbers.
摘要翻译：本发明涉及修饰的亚苄基-γ-丁内酯，其制备方法和用作UV吸收剂，例如在药物和化妆品组合物，防晒剂，日托和护发产品中，用于改进工业产品如油漆，表面涂料，塑料，纺织品，包装材料和橡胶。

4. 发明授权

US5961960A Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation 失效
公开(公告)号：US5961960A
公开(公告)日：1999-10-05
申请号：US969331
申请日：1997-11-13
申请人： Erich Dilk , Roland Langner , William Johncock
发明人： Erich Dilk , Roland Langner , William Johncock
IPC分类号： A61K8/00 , A61K8/49 , A61Q5/02 , A61Q17/04 , C07D235/20 , C07D413/04 , C07D417/04 , C09K3/00 , A61K7/42 , A61K7/00 , A61K31/425
CPC分类号： C07D413/04 , A61K8/49 , A61K8/4946 , A61Q17/04 , A61Q5/02 , C07D235/20 , C07D417/04
摘要： The invention relates to N-substituted benzazoles, processes for their preparation and their use as UV absorbers.

5. 发明授权

US09676691B2 Method for producing indanone derivatives 有权
公开(公告)号：US09676691B2
公开(公告)日：2017-06-13
申请号：US14241964
申请日：2012-08-24
申请人： Oskar Koch , Dietmar Schatkowski , William Johncock , Christel Jahnke , Karl-Georg Fahlbusch
发明人： Oskar Koch , Dietmar Schatkowski , William Johncock , Christel Jahnke , Karl-Georg Fahlbusch
IPC分类号： C07C45/65 , C07C49/755 , A61K8/35 , A61Q17/04 , A61Q19/00 , C07C45/74 , C07C45/72
CPC分类号： C07C45/65 , A61K8/35 , A61Q17/04 , A61Q19/00 , C07C45/72 , C07C45/74 , C07C49/755 , C07C49/683
摘要： A method is described for producing a compound having the formula (I) or an admixture comprising a compound having the formula (I), having the following steps: dissolving an indanone having the formula (II) in a solvent or in an admixture which contains a solvent, the solvent being selected from the group of solvents which form an azeotrope with water, converting the indanone having the formula (II) with an aromatic aldehyde having the formula (III) in the presence of at least one organic base, according to the drawing: where R1 and R2 independently of each other signify hydrogen or a branched or unbranched alkyl group having from 1 to 12 carbon atoms and where R3, R4, R5, R6, R7, R8, R9, R10 and R11 independently of each other signify hydrogen, hydroxy or a branched or unbranched alkyl or alkoxy group having from 1 to 12 carbon atoms and removing water formed from the reaction admixture during the conversion. An admixture comprising a compound of the formula (I) and other components is further described.

6. 发明授权

US06037473A Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation 失效
标题翻译：使用取代的苯并唑作为紫外线吸收剂，新的苯并唑及其制备方法
公开(公告)号：US06037473A
公开(公告)日：2000-03-14
申请号：US298317
申请日：1999-04-23
申请人： Erich Dilk , Roland Langner , William Johncock
发明人： Erich Dilk , Roland Langner , William Johncock
IPC分类号： C07D235/14 , C07D413/04 , C07D417/04 , C07D403/04
CPC分类号： C07D413/04 , C07D235/14 , C07D417/04
摘要： The invention relates to N-substituted benzazoles, processes for their preparation and their use as UV absorbers.
摘要翻译：本发明涉及N-取代的苯并唑，其制备方法及其作为UV吸收剂的用途。

7. 发明申请

US20080050319A1 Benzylidene-Alpha-Dicarbonyl Compounds as Novel Uv Absorbers 审中-公开
标题翻译：亚苄基-α-二羰基化合物作为新型吸收剂
公开(公告)号：US20080050319A1
公开(公告)日：2008-02-28
申请号：US11568606
申请日：2005-04-26
申请人： Oskar Koch , William Johncock
发明人： Oskar Koch , William Johncock
IPC分类号： A61K8/37 , A61K8/35 , A61Q17/04
CPC分类号： A61K8/35 , A61K8/37 , A61Q17/04
摘要： The use of a compound of the formula wherein R1-R3 independently of one another are hydrogen, C1-C8-alkyl or C1-C8-alkoxy, R4 is COR, CO2R, CONR2, where R is C1-C8-alkyl or C3-C8-cycloalkyl R5 is H or C1-C8-alkyl, R6 is aryl, aryl substituted by up to three C1-C8-alkyl- or C1-C8-alkoxy, or C3-C8-cycloalkyl as UV filters in cosmetic formulations, in particular in combination with UV filters from the group consisting of methoxycinnamate derivatives and/or dibenzoylmethane derivatives, with the proviso that R5 is H if R4 is COR, is described.
摘要翻译：使用下式化合物其中R 1〜R 3彼此独立地为氢，C 1 -C 8烷基 C 1 -C 6烷基或C 1 -C 8 - 烷氧基，R 4是COR，CO 2 CO 2， R，CONR 2，其中R是C 1 -C 8 - 烷基或C 3 -C 3 > 8个环烷基R 5是H或C 1 -C 8 - 烷基，R 6 O >是芳基，被至多三个C 1 -C 8 - 烷基 - 或C 1 -C 8 - 取代的芳基，作为化妆品制剂中的UV过滤剂，特别是与来自甲氧基肉桂酸酯衍生物和/或其盐的UV过滤器组合，或二苯甲酰甲烷衍生物，条件是如果R 4为COR，则R 5为H。

8. 发明申请

US20150071866A1 METHOD FOR PRODUCING INDANONE DERIVATIVES 有权
标题翻译：生产吲哚酮衍生物的方法
公开(公告)号：US20150071866A1
公开(公告)日：2015-03-12
申请号：US14241964
申请日：2012-08-24
申请人： Oskar Koch , Dietmar Schatkowski , William Johncock , Christel Jahnke , Karl-Georg Fahlbusch
发明人： Oskar Koch , Dietmar Schatkowski , William Johncock , Christel Jahnke , Karl-Georg Fahlbusch
IPC分类号： C07C45/65 , C07C49/755
CPC分类号： C07C45/65 , A61K8/35 , A61Q17/04 , A61Q19/00 , C07C45/72 , C07C45/74 , C07C49/755 , C07C49/683
摘要： A method is described for producing a compound having the formula (I) or an admixture comprising a compound having the formula (I), having the following steps: dissolving an indanone having the formula (II) in a solvent or in an admixture which contains a solvent, the solvent being selected from the group of solvents which form an azeotrope with water, converting the indanone having the formula (II) with an aromatic aldehyde having the formula (III) in the presence of at least one organic base, according to the drawing: where R1 and R2 independently of each other signify hydrogen or a branched or unbranched alkyl group having from 1 to 12 carbon atoms and where R3, R4, R5, R6, R7, R8, R9, R10 and R11 independently of each other signify hydrogen, hydroxy or a branched or unbranched alkyl or alkoxy group having from 1 to 12 carbon atoms and removing water formed from the reaction admixture during the conversion. An admixture comprising a compound of the formula (I) and other components is further described.
摘要翻译：描述了制备具有式（I）的化合物或包含具有式（I）的化合物的混合物的方法，其具有以下步骤：将具有式（II）的茚酮溶解在溶剂或混合物中溶剂，选自与水形成共沸物的溶剂组，在至少一种有机碱的存在下，用式（III）的芳族醛转化具有式（II）的二氢化茚，根据其中R1和R2彼此独立地表示氢或具有1至12个碳原子的支链或非支链烷基，并且其中R3，R4，R5，R6，R7，R8，R9，R10和R11彼此独立地表示表示氢，羟基或具有1至12个碳原子的支链或非支链烷基或烷氧基，并且在转化期间除去由反应混合物形成的水。进一步描述包含式（I）化合物和其它组分的混合物。

9. 发明授权

US08647651B2 Synergistic mixtures of C6- to C12-alkanediols and tropolone (derivatives) 有权
标题翻译： C6-至C12-烷二醇与托普龙酮（衍生物）的协同混合物
公开(公告)号：US08647651B2
公开(公告)日：2014-02-11
申请号：US11460587
申请日：2006-07-27
申请人： Gerhard Schmaus , Sabine Lange , Ravikumar Pillai , William Johncock
发明人： Gerhard Schmaus , Sabine Lange , Ravikumar Pillai , William Johncock
IPC分类号： A01N31/02 , A01N35/06
CPC分类号： A01N35/06 , A01N31/02 , A01N2300/00
摘要： Antimicrobial mixtures comprising or consisting of: one or more branched or unbranched alkanediols having 6-12 carbon atoms, one, two or more compounds chosen from the group consisting of the tropolones of the formula (I) wherein the substituents R1, R2, R3, R4 and R5 independently of one another have the following meaning: H; linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; OH; OR6, wherein R6 is a linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; COOH; COOR7, wherein R7 is a linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; NO2; NH2; F, Cl, Br, I; are described.
摘要翻译：包含或由以下组成的抗微生物混合物：一种或多种具有6-12个碳原子的支链或非支链烷二醇，一种，两种或更多种选自式（I）的托乐酮的化合物，其中取代基R 1，R 2，R 3， R 4和R 5彼此独立地具有以下含义：H; 具有至多30个C原子的直链或支链，饱和或不饱和的脂族烃基; 哦; OR 6，其中R 6是具有至多30个C原子的直链或支链饱和或不饱和的脂族烃基; COOH; COOR 7，其中R 7是具有至多30个C原子的直链或支链饱和或不饱和的脂族烃基; NO2; NH2; F，Cl，Br，I; 被描述。

10. 发明申请

US20070059331A1 SYNERGISTIC MIXTURES OF C6- TO C12-ALKANEDIOLS AND TROPOLONE (DERIVATIVES) 有权
标题翻译： C6-对C12-烷烃和三聚氰胺（衍生物）的协同混合物
公开(公告)号：US20070059331A1
公开(公告)日：2007-03-15
申请号：US11460587
申请日：2006-07-27
申请人： Gerhard Schmaus , Sabine Lange , Ravikumar Pillai , William Johncock
发明人： Gerhard Schmaus , Sabine Lange , Ravikumar Pillai , William Johncock
IPC分类号： A01N35/00 , A01N31/00
CPC分类号： A01N35/06 , A01N31/02 , A01N2300/00
摘要： Antimicrobial mixtures comprising or consisting of: one or more branched or unbranched alkanediols having 6-12 carbon atoms, one, two or more compounds chosen from the group consisting of the tropolones of the formula (I) wherein the substituents R1, R2, R3, R4 and R5 independently of one another have the following meaning: H; linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; OH; OR6, wherein R6 is a linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; COOH; COOR7, wherein R7 is a linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; NO2; NH2; F, Cl, Br, I; are described.
摘要翻译：包含或由以下组成的抗微生物混合物：一种或多种具有6-12个碳原子的支链或非支链烷二醇，一种，两种或更多种选自式（I）的托乐酮的化合物，其中取代基R 1，R 2，R 3， R 4和R 5彼此独立地具有以下含义：H; 具有至多30个C原子的直链或支链，饱和或不饱和的脂族烃基; 哦; OR 6，其中R 6是具有至多30个C原子的直链或支链饱和或不饱和的脂族烃基; COOH; COOR 7，其中R 7是具有至多30个C原子的直链或支链饱和或不饱和的脂族烃基; NO 2 NH 2; F，Cl，Br，I; 被描述。

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