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1. 发明申请

US20060275785A1 Species-specific primer sets and identification of species-specific DNA sequences using genome fragment enrichment 有权
公开(公告)号：US20060275785A1
公开(公告)日：2006-12-07
申请号：US11316888
申请日：2005-12-27
申请人： Orin Shanks , Jorge Domingo , James Graham , Jingrang Lu
发明人： Orin Shanks , Jorge Domingo , James Graham , Jingrang Lu
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6809 , C12Q1/6832 , C12Q1/689 , C12Q2563/131 , C12Q2537/161
摘要： Targeted sequencing of genetic regions that differ between two DNA preparations uses genomic fragment enrichment. This method can be used to study genetic variation among closely related species and microbial communities.

2. 发明授权

US09629752B1 Welding helmet with a sensor-operated light and photochromic visor lens 有权
公开(公告)号：US09629752B1
公开(公告)日：2017-04-25
申请号：US14686122
申请日：2015-04-14
申请人： James Graham
发明人： James Graham
IPC分类号： A61K9/06 , B23K31/02 , A61F9/06
CPC分类号： A61F9/067
摘要： A welding helmet with a sensor-operated light and photochromic visor lens including a welding helmet body configured, sized, and shaped to cover and substantially conform to a welder's forehead. A frustoconical protrusion, integrated into a front side of the welding helmet body, houses a battery-operated LED light bulb. At least one photosensor is disposed proximal the protrusion. Upon the detection of a welding arc by the at least one photosensor, an auto-darkening filtered visor lens darkens and the LED light bulb in activated. A battery compartment, an on-off switch, and a microchip are disposed on a rear side of the welding helmet body. A padded length-adjustable strap is pivotally disposed across the rear side of the welding helmet body.

3. 发明申请

US20080006157A1 Activated carbon for odor control and method for making same 有权
标题翻译：用于气味控制的活性炭及其制备方法
公开(公告)号：US20080006157A1
公开(公告)日：2008-01-10
申请号：US11825843
申请日：2007-07-09
申请人： James Graham
发明人： James Graham
IPC分类号： B01D53/02
CPC分类号： B01J20/3042 , A61L9/014 , B01D53/02 , B01D53/8668 , B01D2251/40 , B01D2253/10 , B01D2253/102 , B01D2253/112 , B01D2257/304 , B01D2257/708 , B01D2257/90 , B01D2258/00 , B01J20/041 , B01J20/20 , B01J20/28026 , B01J20/2803 , B01J20/3007 , B01J20/3021 , B01J20/3078 , B01J21/18 , B01J23/02 , B01J37/0201 , B01J37/04 , B01J37/14 , B01J2220/42 , C01B32/30 , C01B32/336 , Y10T428/30
摘要： An activated carbon-metal oxide matrix is disclosed. The activated carbon-metal oxide matrix may be obtained by a method including the steps of: preoxidizing a carbon material, grinding the preoxidized carbon material; mixing the ground preoxidized material with a metal oxide to form a carbon mixture; extruding the carbon mixture; carbonizing and activating the extrudate. The activated carbon-metal oxide matrix may be used to remove odorous compounds, acidic gases, and volatile organic compounds from a gas.
摘要翻译：公开了一种活性炭 - 金属氧化物基质。活性炭 - 金属氧化物基质可以通过包括以下步骤的方法获得：将碳材料预氧化，研磨预氧化碳材料; 将地面预氧化材料与金属氧化物混合以形成碳混合物; 挤出碳混合物; 碳化和活化挤出物。活性炭 - 金属氧化物基质可用于从气体中除去有气味的化合物，酸性气体和挥发性有机化合物。

4. 发明申请

US20070241219A1 APPARATUS AND METHODOLOGY FOR COMMINUTING MATERIALS 有权
标题翻译：装置和材料的方法学
公开(公告)号：US20070241219A1
公开(公告)日：2007-10-18
申请号：US11697251
申请日：2007-04-05
申请人： Lynn Tessier , James Graham , Russell Graham
发明人： Lynn Tessier , James Graham , Russell Graham
IPC分类号： B02C19/00
CPC分类号： B02C19/0025 , B02C13/1814 , B02C2013/1857
摘要： A comminuting apparatus has a coaxial throwing wheel and impact rotor, the throwing wheel preferably comprising a plurality of channels for conducting particles from a central axis inlet to a plurality of particle exits to impact the impact rotor. The throwing wheel can be an assembly of wear-resistant inserts forming the channels. Flow channels through the throwing wheel can be configured, such as converging towards the particle exits to minimize energy loss during acceleration of the particles. Further, the comminuting apparatus can include a housing for ready access to the throwing wheel and impact rotor. A two-part housing is reversibly separable for accessing the comminuting chamber, throwing wheel and impact rotor within.
摘要翻译：粉碎设备具有同轴投掷轮和冲击转子，抛掷轮优选地包括多个通道，用于将颗粒从中心轴入口传导到多个颗粒出口以冲击冲击转子。抛掷轮可以是形成通道的耐磨插件的组件。可以配置通过投掷轮的流动通道，例如朝着颗粒出口收敛，以最小化加速颗粒期间的能量损失。此外，粉碎设备可以包括用于准备进入投掷轮和冲击转子的壳体。两部分壳体可逆地分离，用于进入粉碎室，投掷轮和冲击转子。

5. 发明申请

US20070224628A1 Protein isoform discrimination and quantitative measurements thereof 失效
标题翻译：蛋白质异构体鉴别及其定量测定
公开(公告)号：US20070224628A1
公开(公告)日：2007-09-27
申请号：US11728185
申请日：2007-03-23
申请人： Neal Gordon , James Graham
发明人： Neal Gordon , James Graham
IPC分类号： C12Q1/68 , G01N33/53 , C12Q1/37 , G01N33/543
CPC分类号： G01N33/6878 , G01N33/6803
摘要： The invention relates to methods, reagents and apparatus for detecting protein isoforms (e.g., those due to alternative splicing, or different disease protein isoforms or degradation products) in a sample, including using combinations of capture agents to identify the isoforms to be detected/measured.
摘要翻译：本发明涉及用于检测样品中蛋白质异构体（例如，由于可选剪接或不同疾病蛋白质同种型或降解产物引起的那些）的方法，试剂和装置，包括使用捕获剂的组合来鉴定待检测/测量的同种型。

6. 发明申请

US20060090336A1 Adaptive machining and weld repair process 有权
标题翻译：自适应加工和焊接修复过程
公开(公告)号：US20060090336A1
公开(公告)日：2006-05-04
申请号：US10976726
申请日：2004-10-29
申请人： James Graham , Jeffrey Reinwand , Roger Coriell , Kevin Lytle
发明人： James Graham , Jeffrey Reinwand , Roger Coriell , Kevin Lytle
IPC分类号： B23P6/00
CPC分类号： B23P6/007 , B23K26/342 , B23K35/0244 , F01D5/005 , F05D2230/234 , F05D2230/80 , Y02T50/673 , Y10T29/49229 , Y10T29/49233 , Y10T29/49236 , Y10T29/49238 , Y10T29/49318 , Y10T29/49336
摘要： The present invention provides an apparatus and method for an adaptive machining and weld repair process useful for repairing airfoils, particularly damage to an airfoil leading edge and tip. The process first machines away damaged portions of an airfoil. Filler material is then added to the machined area through a process such as laser welding. At this point, the actual profile of the welded airfoil is measured using a Coordinate Measuring Machine. This data is then used to generate a “deformation” profile, an airfoil profile that approximates the ideal shape of the airfoil. The airfoil is then machined using the date of the deformation profile to produce that shape. The adaptive technology minimizes the amount of stock on material that needs to be removed by hand. The technique thereby significantly reduces costly manual processing.
摘要翻译：本发明提供了一种用于修复机翼的自适应加工和焊接修复过程的装置和方法，特别是对翼型前缘和尖端的损伤。该过程首先将机翼的损坏部分进行切割。然后通过激光焊接等方法将填充材料加入加工区域。此时，使用坐标测量机测量焊接翼型件的实际轮廓。然后将该数据用于产生近似于翼型理想形状的“变形”轮廓。然后使用变形曲线的日期来加工翼型件以产生该形状。自适应技术最大限度地减少需要用手去除的材料上的库存量。因此，该技术显着地降低了昂贵的手工处理。

7. 发明申请

US20050100491A1 Activated carbon for odor control and method for making same 有权
标题翻译：用于气味控制的活性炭及其制备方法
公开(公告)号：US20050100491A1
公开(公告)日：2005-05-12
申请号：US11008449
申请日：2004-12-09
申请人： James Graham , Cheng Yuan
发明人： James Graham , Cheng Yuan
IPC分类号： B01D53/38 , B01D53/02 , B01D53/04 , B01D53/81 , B01D53/86 , B01J20/04 , B01J20/20 , B01J20/28 , B01J20/30 , B01J21/18 , C01B31/08 , C01B31/10 , C01B3/00 , B01D47/00 , B01J8/00 , B01J20/02 , C01B7/00 , C01B21/00 , C07C11/24
CPC分类号： B01J20/3042 , A61L9/014 , B01D53/02 , B01D53/8668 , B01D2251/40 , B01D2253/10 , B01D2253/102 , B01D2253/112 , B01D2257/304 , B01D2257/708 , B01D2257/90 , B01D2258/00 , B01J20/041 , B01J20/20 , B01J20/28026 , B01J20/2803 , B01J20/3007 , B01J20/3021 , B01J20/3078 , B01J21/18 , B01J23/02 , B01J37/0201 , B01J37/04 , B01J37/14 , B01J2220/42 , C01B32/30 , C01B32/336 , Y10T428/30
摘要： An activated carbon-metal oxide matrix is disclosed. The activated carbon-metal oxide matrix may by obtained by a method including the steps of: preoxidizing a carbon material, grinding the preoxidized carbon material; mixing the ground preoxidized material with a metal oxide to form a carbon mixture; extruding the carbon mixture; carbonizing and activating the extrudate. The activated carbon-metal oxide matrix may be used to remove odorous compounds, acidic gases, and volatile organic compounds from a gas.
摘要翻译：公开了一种活性炭 - 金属氧化物基质。活性炭 - 金属氧化物基质可以通过包括以下步骤的方法获得：将碳材料预氧化，研磨预氧化碳材料; 将地面预氧化材料与金属氧化物混合以形成碳混合物; 挤出碳混合物; 碳化和活化挤出物。活性炭 - 金属氧化物基质可用于从气体中除去有气味的化合物，酸性气体和挥发性有机化合物。

8. 发明授权

US06678881B2 Representing a path as an object with transformation capability 有权
标题翻译：将路径表示为具有转换能力的对象
公开(公告)号：US06678881B2
公开(公告)日：2004-01-13
申请号：US09847112
申请日：2001-05-01
申请人： James Graham
发明人： James Graham
IPC分类号： G06F945
CPC分类号： G06T11/203
摘要： One or more embodiments provide the ability to use multiple path formats in an object oriented system. A path maintains the ability to translate itself into a recognizable format for use by applications. The recognizable format may be a standard Bezier Path format or an iterator that provides the ability to iterate along the path, one curve segment at a time. Multiple applications may use the self-translation ability. In one embodiment, when an application desires to perform a transform, it determines if the transform may be performed on the path (i.e., whether the path is recognizable). If the path is recognizable, the transform is performed directly on the path. If the path is not recognizable, the path translates itself into a recognizable format and the transform performs the action on the recognizable path (the transform must maintain the ability to perform the transform on the standard format). Determining whether the path is recognizable may consist of a two stage negotiation process. During the first stage the path determines if it recognizes the transform. If the path does not recognize the transform, the desired operation is passed onto the transform in the second stage where it is determined if the transform recognizes the path. If the path or the transform is recognizable in either stage the action is performed. However, in the second stage, if the path is not recognizable, the transform requests the path to translate itself and performs the operation on the recognizable path returned.
摘要翻译：一个或多个实施例提供在面向对象的系统中使用多个路径格式的能力。路径保持将自身转换为可识别的格式以供应用程序使用的能力。可识别的格式可以是标准的贝塞尔路径格式或迭代器，它提供沿路径迭代的能力，一次一条曲线段。多个应用程序可能会使用自我翻译功能。在一个实施例中，当应用程序希望执行变换时，它确定是否可以在路径上执行变换（即，路径是否可识别）。如果路径是可识别的，则直接在路径上执行变换。如果路径不可识别，则路径将其自身转换为可识别的格式，并且变换在可识别的路径上执行动作（转换必须保持执行标准格式转换的能力）。确定路径是否可识别可能包括两阶段协商过程。在第一阶段，路径确定它是否识别变换。如果该路径不识别该变换，则在第二阶段中将转换所需的操作传递到确定变换是否识别该路径的变换。如果路径或变换在任一阶段都可识别，则执行该操作。然而，在第二阶段，如果路径不可识别，则变换请求路径自身翻译，并对所返回的可识别路径执行操作。

9. 发明授权

US06346948B1 Method and apparatus for pixel composition 有权
标题翻译：像素组成的方法和装置
公开(公告)号：US06346948B1
公开(公告)日：2002-02-12
申请号：US09498197
申请日：2000-02-04
申请人： Jerald Evans , James Graham , Thanh Nguyen
发明人： Jerald Evans , James Graham , Thanh Nguyen
IPC分类号： G06T1160
CPC分类号： G06T15/503
摘要： The present invention provides a method and apparatus that permits the introduction of customized compositing techniques into an application by a developer. A Composite interface and a CompositeContext interface are defined. Custom compositing operations can be defined by implementing these interfaces. A Composite object provides a CompositeContext object that holds the state and performs the compositing work. Multiple CompositeContext objects can be created from one Composite object to maintain separate states in a multi-threaded environment. An object implementing the Composite interface can be set as rendering state on a graphics object that provides rendering methods. This allows arbitrary compositing rules to be used by a developer. In one implementation of the Composite and CompositeContext interfaces, an AlphaComposite class is defined. The AlphaComposite class implements common compositing rules, such as defined by Porter and Duff, for combining source and destination pixels to achieve blending and transparency effects with graphics and images.
摘要翻译：本发明提供一种方法和装置，其允许将定制的合成技术引入开发者的应用中。定义了Composite接口和CompositeContext接口。可以通过实现这些接口来定义自定义合成操作。 Composite对象提供了一个保存状态并执行合成工作的CompositeContext对象。可以从一个Composite对象创建多个CompositeContext对象，以在多线程环境中维护单独的状态。实现Composite接口的对象可以在提供渲染方法的图形对象上设置为渲染状态。这允许开发人员使用任意合成规则。在Composite和CompositeContext接口的一个实现中，定义了AlphaComposite类。 AlphaComposite类实现了常见的合成规则，例如由Porter和Duff定义，用于组合源和目标像素，以实现图形和图像的混合和透明效果。

10. 发明授权

US5852173A TNF receptor death ligand proteins and inhibitors of ligand binding 失效
标题翻译： TNF受体死亡配体蛋白和配体结合抑制剂
公开(公告)号：US5852173A
公开(公告)日：1998-12-22
申请号：US533901
申请日：1995-09-26
申请人： Lih-Ling Lin , Jennifer Chen , Andrea R. Schievella , James Graham
发明人： Lih-Ling Lin , Jennifer Chen , Andrea R. Schievella , James Graham
IPC分类号： C12N15/09 , A61K38/00 , A61K45/00 , A61K48/00 , A61P29/00 , C07K14/47 , C07K14/715 , C07K16/24 , C12N1/19 , C12N5/10 , C12N15/12 , C12P21/02 , C07K14/52 , C12N15/10
CPC分类号： C07K14/4743 , C07K14/47 , C07K16/24 , A61K38/00 , C07K2317/34
摘要： Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
摘要翻译：公开了新型TNF受体死亡结构域（“TNF-R1-DD”）配体蛋白。还公开了编码TNF-R1-DD配体蛋白的多核苷酸以及载体，宿主细胞和制备TNF-R1-DD配体蛋白的方法。还公开了含有TNF-R1-DD配体蛋白质的药物组合物，治疗炎性病症的方法和抑制TNF-R死亡结构域结合的方法。还公开了鉴定TNF-R死亡结构域结合抑制剂的方法和通过这些方法鉴定的抑制剂。

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