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    • 10. 发明授权
    • Hydrolytically decomposable ionic copolymers
    • 水解可分解的离子共聚物
    • US09068065B2
    • 2015-06-30
    • US12937631
    • 2009-04-09
    • Andreas GreinerSeema AgarwalThomas KisselLiqun Ren
    • Andreas GreinerSeema AgarwalThomas KisselLiqun Ren
    • C08F20/06C08L101/16C08F8/44C08F220/34C08F216/38C08F220/14
    • C08L101/16C08F8/44C08F216/38C08F220/14C08F220/34C08F2800/10C08F120/34
    • The invention at hand provides hydrolytically degradable ionic copolymers. These ionic copolymerizates are composed of one cyclic ketene acetal A, one anionic or cationic methacrylic acid derivative B, selected from 2-methyl-methacrylate, [2-(2-methyl-1-methylene-allyloxy)]ethanesulfonate, [2-(2-methyl-1-methylene-allyloxy)ethyl]phosphonate or a quaternary amine of the N,N-dimethylaminoethylmethacrylic acid (DMAEMA) and, optionally, a neutral methacrylic acid derivative C.The hydrolytically degradable anionic copolymers according to the present invention are produced by polymerizing the components A, B and C in the presence of a radical initiator under inert gas atmosphere and subsequent purification.All copolymers according to the present invention are hydrolytically degradable. Copolymers comprising a maximum of 40 mol-% of ester groups in the backbone are additionally biodegradable, wherein in the case of cationic copolymers a maximum of 20 mol-% of quaternized DMAEMA is allowed to be available.Cationic copolymers comprising at least 50 mol-% of the component B are antimicrobial.Both anionic as well as cationic copolymers are suitable for producing nanoparticles. Cationic copolymers are suitable for being used as superhydrophobic materials as well as adhesives. Anionic copolymers are suitable for biodegradable thermoplastic elastomers and for biodegradable ionomers.
    • 本发明提供了可水解降解的离子共聚物。 这些离子共聚物由选自2-甲基 - 甲基丙烯酸酯,[2-(2-甲基-1-亚甲基 - 烯丙氧基)]乙磺酸酯,[2-(2-甲基-1-亚甲基 - 烯丙氧基)]乙磺酸的一种环状烯酮缩醛A,一种阴离子或阳离子甲基丙烯酸衍生物B组成, 2-甲基-1-亚甲基 - 烯丙氧基)乙基]膦酸酯或N,N-二甲基氨基乙基甲基丙烯酸(DMAEMA)和任选的中性甲基丙烯酸衍生物C的季胺。根据本发明的可水解降解的阴离子共聚物是 通过在惰性气体气氛下在自由基引发剂的存在下将组分A,B和C聚合并随后纯化而制备。 根据本发明的所有共聚物都是可水解降解的。 在主链中包含最多40mol%的酯基的共聚物另外是可生物降解的,其中在阳离子共聚物的情况下,允许最多20mol%的季铵化DMAEMA可用。 包含至少50mol%的组分B的阳离子共聚物是抗微生物剂。 阴离子和阳离子共聚物都适用于生产纳米颗粒。 阳离子共聚物适合用作超疏水材料以及粘合剂。 阴离子共聚物适用于可生物降解的热塑性弹性体和可生物降解的离聚物。