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    • 4. 发明申请
    • Cell culture patterning substrate
    • 细胞培养图案化底物
    • US20070148762A1
    • 2007-06-28
    • US10589376
    • 2005-02-18
    • Hideyuki MiyakeHideshi HattoriHironori KobayashiHidetsugu Tazawa
    • Hideyuki MiyakeHideshi HattoriHironori KobayashiHidetsugu Tazawa
    • C12M3/00
    • C12N5/0068C12N2533/30C12N2535/10
    • A cell culture patterning substrate on which cells can be arranged regularly with high efficiency over a large area on a base material so as to attain formation of a tissue, etc. The cell culture patterning substrate includes: a base material; and a cell culture region which is formed on the base material, is a region for culturing a cell and contains a cell adhesive layer having adhesive properties to the cell. The cell culture region includes: a cell adhesion portion at which the cell adhesive layer is formed; and a cell adhesion auxiliary portion, formed in a pattern, which inhibits adhesion to the cell, and the cell adhesion auxiliary portion is formed such that, upon adhesion of the cell to the cell adhesion portion, the cells on two cell adhesion portions adjacent to the cell adhesion auxiliary portion can be bound to each other on the cell adhesion auxiliary portion.
    • 一种细胞培养图案形成基板,其上可以在基材上大面积地高效率地排列细胞以形成组织等。细胞培养图案形成基板包括:基材; 并且在基材上形成的细胞培养区是用于培养细胞的区域,并且含有对细胞具有粘合性的细胞粘合剂层。 细胞培养区域包括:形成细胞粘合剂层的细胞粘附部分; 和形成为抑制与细胞粘合的图案的细胞粘附辅助部分和细胞粘附辅助部分形成,使得当细胞粘附到细胞粘附部分时,细胞粘附在两个细胞粘附部分上 细胞粘附辅助部分可以在细胞粘附辅助部分上彼此结合。