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    • 2. 发明申请
    • STRUCTURE FOR SUPPRESSING FLOW VIBRATION OF INSTRUMENTATION GUIDE TUBE
    • 用于抑制仪表导管流动振动的结构
    • US20100091929A1
    • 2010-04-15
    • US12527484
    • 2009-02-22
    • Nobuki UdaShigeyuki WatanabeKazuo HirotaHideyuki SakataHideyuki MoritaMakoto NakajimaChikara KurimuraToshio Ichikawa
    • Nobuki UdaShigeyuki WatanabeKazuo HirotaHideyuki SakataHideyuki MoritaMakoto NakajimaChikara KurimuraToshio Ichikawa
    • G21C17/10
    • G21C17/10G21C3/322G21C17/08
    • An upper hole 37A and a lower hole 37B are provided at two positions, namely, upper and lower portions, of a side surface of a guide tube 27, and a thimble tube 22 is pressed against an inner circumferential surface of the guide tube 27, by a differential pressure between coolant inside and outside the upper hole 37A and the lower hole 37B. It is preferable that an upper pressure adjustment hole and a lower pressure adjustment hole are provided at two positions, namely, upper and lower portions, of a side surface of an upper core support column 21, and a coolant flowing into the guide tube from an upper end of the guide tube flows out to the outside from inside the guide tube through a gap between the thimble tube and the upper hole, and also flows out to the outside from inside the upper core support column through the upper pressure adjustment hole, and a coolant flowing into the guide tube from a lower end of the guide tube flows out to the outside from inside the guide tube through a gap between the thimble tube and the lower hole, and also flows out to the outside from inside the upper core support column through the lower pressure adjustment hole.
    • 在引导管27的侧面的两个位置,即上下部分设置有上孔37A和下孔37B,并且将套管22压靠在引导管27的内周面上, 通过上部孔37A和下部孔37B的内部和外部的冷却剂之间的压力差。 优选的是,上压力调节孔和下压力调节孔设置在上芯支撑柱21的侧表面的两个位置,即上部和下部,以及从上部芯支撑柱21的侧表面流入导管的冷却剂 引导管的上端通过引导管和上孔之间的间隙从导管的内部流出到外部,并且还通过上压力调节孔从上芯支撑柱的内部流出到外部,并且 从引导管的下端流入引导管的冷却剂通过引导管和下孔之间的间隙从引导管的内部流出到外部,并且还从上部芯支撑体内部流出到外部 柱通过下压力调节孔。
    • 3. 发明授权
    • Internal structure of nuclear reactor with coolant flow stabilizing facility
    • 具有冷却剂流动稳定设施的核反应堆内部结构
    • US06445758B1
    • 2002-09-03
    • US09416933
    • 1999-10-13
    • Hajime IzumiMakoto NakajimaChikara KurimuraTakehiko TsutsuiNoboru KuboMikio KuriharaToshio Ichikawa
    • Hajime IzumiMakoto NakajimaChikara KurimuraTakehiko TsutsuiNoboru KuboMikio KuriharaToshio Ichikawa
    • G21C1502
    • G21C15/14G21Y2002/204G21Y2004/302Y02E30/32
    • Within an upper plenum of a nuclear reactor, a portion of a heated coolant flows radially outward from a central portion of a core barrel (30) towards outlet nozzles (12) in a region of an upper core plate (21) extending outside of an outer periphery of the core along an inner wall of a core barrel (30). Portions of the coolant flows beneath the outlet nozzles (12). Thus, streams of heated coolant flowing in opposite directions may collide with each other. After collision, the flow directions of the heated coolant are changed to flow upward. Due to the collision, the coolant flow behavior becomes complicated and unstable, making it difficult to measure the temperature of the heated coolant with an outlet pipe (42) connected to the outlet nozzle (12). Within an upper plenum (40) defined above a fuel region through which a coolant flows and which is hydraulically communicated with a plurality of outlet nozzles (12) mounted on a side wall of a nuclear reactor vessel (10), short flow stabilizing members (1) each being lower than the outlet nozzle (12) are disposed in the vicinity of a core barrel (30) in an region outside of the fuel region.
    • 在核反应堆的上部增压室内,加热的冷却剂的一部分从芯筒(30)的中心部分向着出口喷嘴(12)径向向外流动,在上芯板(21) 芯沿着芯筒(30)的内​​壁的外周。 冷却剂的一部分流过出口喷嘴(12)。 因此,沿相反方向流动的加热的冷却剂流可能彼此碰撞。 在碰撞之后,加热的冷却剂的流动方向被改变以向上流动。 由于碰撞,冷却剂流动行为变得复杂和不稳定,使得难以用连接到出口喷嘴(12)的出口管(42)来测量加热的冷却剂的温度。 在位于冷却剂流过的燃料区域上方并且与安装在核反应堆容器(10)的侧壁上的多个出口喷嘴(12)液压连通的燃料区域上方的上部空气室(40)内,短流动稳定构件 每个低于出口喷嘴(12)的喷嘴(1)设置在燃料区域外侧的区域中的芯筒(30)附近。
    • 4. 发明授权
    • Apparatus for promoting intermixing of heated coolant streams in nuclear reactor
    • 用于促进核反应堆中加热的冷却剂流的混合的装置
    • US06173028B2
    • 2001-01-09
    • US09258838
    • 1999-02-26
    • Toshio IchikawaYoko MatsushimaTakehiko TsutsuiChikara KurimuraHajime Izumi
    • Toshio IchikawaYoko MatsushimaTakehiko TsutsuiChikara KurimuraHajime Izumi
    • G21C1500
    • G21C5/02G21C15/14G21Y2002/204G21Y2002/303G21Y2004/302Y02E30/40
    • An apparatus for promoting intermixing of heated fluid streams within a nuclear reactor vessel is implemented in such structural configuration and disposition as to be capable of not only promoting uniform temperature distribution of a heated fluid stream flowing into an outlet nozzle but also reducing flow resistance which the heated fluid encounters within a upper plenum of the reactor vessel. The apparatus is disposed within a upper plenum (40) defined within a nuclear reactor vessel (10) of a nuclear reactor above a core having a low temperature region (a) and a high temperature region (d) where a heated fluid flows at a low temperature and a high temperature, respectively. The upper plenum (40) is hydraulically communicated to outlet nozzles (12) installed at a side wall of the nuclear reactor vessel (10). The apparatus includes heated fluid guide members each having a predetermined short length and installed within the upper plenum (40) for guiding a heated fluid (b′) flowing out from the low temperature region of the reactor core to the vicinity of the outlet nozzle (12).
    • 用于促进核反应堆容器内的加热流体流的混合的装置以这样的结构构造和布置实现,以便不仅可以促进流入出口喷嘴的加热流体流的均匀温度分布,而且还可降低流动阻力, 在反应器容器的上部增压室内遇到加热的流体。 该装置设置在限定在具有低温区域(a)和高温区域(d)的核心上方的核反应堆的核反应堆容器(10)内的上部增压室(40)中,其中加热的流体在 低温和高温。 上部空间(40)液压地连通到安装在核反应堆容器(10)的侧壁处的出口喷嘴(12)。 该装置包括各自具有预定短长度的加热流体引导构件,并且安装在上部空间(40)内,用于将从反应堆芯的低温区域流出的加热流体(b')引导到出口喷嘴附近 12)。
    • 10. 发明授权
    • Mutant uricase, a mutant uricase gene, a novel recombinant DNA, and a
process for producing mutant uricase
    • 突变型尿酸酶,突变型尿酸酶基因,新型重组DNA,以及生产突变型尿酸酶的方法
    • US5700674A
    • 1997-12-23
    • US701952
    • 1996-08-23
    • Yasuji KoyamaToshio Ichikawa
    • Yasuji KoyamaToshio Ichikawa
    • C12N15/09C07H21/04C12N9/06C12R1/19C12N1/20C12P21/06
    • C12N9/0046
    • The present invention relates to mutant uricase containing the amino acid sequence of wild-type uricase shown in SEQ ID NO: 1 wherein the 165-170th amino acids contain a mutated amino acid sequence, a mutant uricase gene coding for said uricase, a recombinant DNA having said mutant uricase gene integrated into a vector DNA, and a process for producing mutant uricase by culturing a microorganism carrying said recombinant DNA and having the ability to produce mutant uricase in a medium, and then recovering mutant uricase from the culture. The present invention provides stable mutant uricase and the gene coding for said mutant uricase, and further the process of the present invention enables efficient production of stable uricase.
    • 本发明涉及包含SEQ ID NO:1所示的野生型尿酸酶的氨基酸序列的突变型尿酸酶,其中第165-170位氨基酸含有突变型氨基酸序列,编码所述尿酸酶的突变型尿酸酶基因,重组DNA 将所述突变型尿酸酶基因整合到载体DNA中,以及通过培养携带所述重组DNA并具有在培养基中产生突变性尿酸酶的能力的微生物,然后从培养物中回收突变性尿酸酶的方法来产生突变型尿酸酶。 本发明提供稳定的突变型尿酸酶和编码所述突变型尿酸酶的基因,进一步本发明的方法能够有效地产生稳定的尿酸酶。