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1. 发明申请

US20140336779A1 COMPRESSED FIBER STRUCTURAL MATERIAL AND METHOD FOR PRODUCING THE SAME 有权
标题翻译：压缩纤维结构材料及其制造方法
公开(公告)号：US20140336779A1
公开(公告)日：2014-11-13
申请号：US14345668
申请日：2012-03-09
申请人： Noboru Nakayama , Masaomi Horita , Naoki Izawa , Hiroto Tamai , Naoto Saito , Yuki Usui , Nobuhide Ogihara
发明人： Noboru Nakayama , Masaomi Horita , Naoki Izawa , Hiroto Tamai , Naoto Saito , Yuki Usui , Nobuhide Ogihara
IPC分类号： A61F2/28
CPC分类号： A61F2/28 , A61F2002/2835 , A61F2310/00023 , A61F2310/00425 , A61L27/04 , B22F3/002 , C22C49/11 , C22F1/183
摘要： Provided is a method for easily producing a lamellar compressed fiber structural material which has mechanical characteristics close to those of in vivo bone and which is capable of easily increasing osteoblast even when a difference in strength exists. In order to solve the issues, the method for producing compressed fiber structural material 1, includes: a step of preparing biocompatible fiber 14 having an average diameter of 5 μm-50 μm and an aspect ratio of 20-500; and a step of molding compressed fiber structural material 1 by cold pressing/shearing biocompatible fiber 14, compressed fiber structural material 1 having an average pore diameter that is in the range of 60 μm-100 μm inclusive and a void fraction that is in the range of 25%-50% inclusive, both obtained by measurement in accordance with the mercury penetration method. Further, it is preferable for the cold pressing/shearing is performed by controlling a compressive pressure in the range of 200 MPa-2000 MPa, a shearing stroke length in the range of 0.2 mm-5 mm and a shearing velocity in the range of 0.5 mm/min-5 mm/min.
摘要翻译：本发明提供一种容易制造层状压缩纤维结构材料的方法，其具有接近体内骨的机械特性，并且即使存在强度差也能够容易地增加成骨细胞。为了解决这些问题，制造压缩纤维结构材料1的方法包括：制备平均直径为5μm〜50μm，长径比为20-500的生物相容性纤维14的工序; 以及通过冷压/剪切生物相容性纤维14成型压缩纤维结构材料1的步骤，平均孔径在60μm-100μm范围内的压缩纤维结构材料1和在该范围内的空隙率为25％-50％，均为根据汞渗透法测量得到的。此外，优选通过将压缩压力控制在200MPa〜2000MPa，剪切行程长度在0.2mm-5mm范围内，剪切速度在0.5的范围内进行冷压/剪切 mm / min-5mm / min。

2. 发明授权

US09320602B2 Compressed fiber structural material and method for producing the same 有权
标题翻译：压缩纤维结构材料及其制造方法
公开(公告)号：US09320602B2
公开(公告)日：2016-04-26
申请号：US14345668
申请日：2012-03-09
申请人： Noboru Nakayama , Masaomi Horita , Naoki Izawa , Hiroto Tamai , Naoto Saito , Yuki Usui , Nobuhide Ogihara
发明人： Noboru Nakayama , Masaomi Horita , Naoki Izawa , Hiroto Tamai , Naoto Saito , Yuki Usui , Nobuhide Ogihara
IPC分类号： A61F2/28 , C22C49/11 , B22F3/00 , C22F1/18 , A61L27/04
CPC分类号： A61F2/28 , A61F2002/2835 , A61F2310/00023 , A61F2310/00425 , A61L27/04 , B22F3/002 , C22C49/11 , C22F1/183
摘要： Provided is a method for easily producing a lamellar compressed fiber structural material which has mechanical characteristics close to those of in vivo bone and which is capable of easily increasing osteoblast even when a difference in strength exists. In order to solve the issues, the method for producing compressed fiber structural material 1, includes: a step of preparing biocompatible fiber 14 having an average diameter of 5 μm-50 μm and an aspect ratio of 20-500; and a step of molding compressed fiber structural material 1 by cold pressing/shearing biocompatible fiber 14, compressed fiber structural material 1 having an average pore diameter that is in the range of 60 μm-100 μm inclusive and a void fraction that is in the range of 25%-50% inclusive, both obtained by measurement in accordance with the mercury penetration method. Further, it is preferable for the cold pressing/shearing is performed by controlling a compressive pressure in the range of 200 MPa-2000 MPa, a shearing stroke length in the range of 0.2 mm-5 mm and a shearing velocity in the range of 0.5 mm/min-5 mm/min.
摘要翻译：本发明提供一种容易制造层状压缩纤维结构材料的方法，其具有接近体内骨的机械特性，并且即使存在强度差也能够容易地增加成骨细胞。为了解决这些问题，制造压缩纤维结构材料1的方法包括：制备平均直径为5μm〜50μm，长径比为20-500的生物相容性纤维14的工序; 以及通过冷压/剪切生物相容性纤维14成型压缩纤维结构材料1的步骤，平均孔径在60μm-100μm范围内的压缩纤维结构材料1和在该范围内的空隙率为25％-50％，均为根据汞渗透法测量得到的。此外，优选通过将压缩压力控制在200MPa〜2000MPa，剪切行程长度在0.2mm-5mm范围内，剪切速度在0.5的范围内进行冷压/剪切 mm / min-5mm / min。

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