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1. 发明申请

US20090110733A1 DELIVERY MEANS 审中-公开
标题翻译：交货方式
公开(公告)号：US20090110733A1
公开(公告)日：2009-04-30
申请号：US12300761
申请日：2007-05-16
申请人： Nicholas John Crowther , Donald Eagland , Stephen Britland
发明人： Nicholas John Crowther , Donald Eagland , Stephen Britland
IPC分类号： A61K9/00 , A61K35/64 , A61P17/02
CPC分类号： A61L26/008 , A61L15/40 , A61L15/60 , A61L26/0057
摘要： A delivery means for delivering a deliverable material to a wound bed comprises a hydrogel (preferably an optionally cross-linked polyvinylalcohol) and a deliverable material comprising: (i) a decomposable material which in the absence of said hydrogel decomposes and/or is permanently denatured if sterilised using heat, electron beam radiation or gamma radiation; (ii) a protein, protein fragment, peptide or amino acid; or (iii) a secretion or excretion from the organism Lucilia sericata or Drosophila melanogaster.
摘要翻译：用于将可递送材料递送到伤口床的递送装置包括水凝胶（优选为任选交联的聚乙烯醇）和可递送材料，其包含：（i）在不存在所述水凝胶的情况下分解和/或永久变性的可分解材料如果使用热，电子束辐射或γ辐射灭菌; （ii）蛋白质，蛋白质片段，肽或氨基酸; 或（iii）分泌或排泄生物Lucilia sericata或果蝇黑腹果蝇。

2. 发明授权

US07202300B2 Dispersion 失效
标题翻译：分散
公开(公告)号：US07202300B2
公开(公告)日：2007-04-10
申请号：US10515589
申请日：2003-06-02
申请人： Donald Eagland , Nicholas John Crowther
发明人： Donald Eagland , Nicholas John Crowther
IPC分类号： C08F246/00 , C08F2/06 , C08F112/32 , C08F116/34 , C08F2/48 , C08L57/00
CPC分类号： C08J3/246 , C08G81/02
摘要： A method of preparing a dispersion which includes the step of contacting a first phase, a first material immiscible therewith, a first polymeric material and a second polymeric material wherein: (a) (i) said first polymeric material has a repeat unit of the formula (I), wherein A and B are the same or different, are selected from optionally-substituted aromatic and thereoaromatic groups and at least one comprises a relatively polar atom or group and R1 and R2 independently comprise relatively non-polar atoms or groups; (ii) said first polymeric material is prepared or preparable by providing a compound of general formula (I), wherein A, B, R1 and R2 are as described above, in an aqueous solvent and causing the groups C═C in said compound to react with one another to form said first polymeric material; (b) said second polymeric material includes a functional group which is able to react with said first polymeric material so that covalent bonds are formed between said first and second polymeric materials; (c) the ratio of the weight of said first polymeric material to the weight of said first phase is equal to or less than 0.0025; and (d) the ratio of the weight of said second polymeric material to the weight of said first phase is equal to or less than 0.035.
摘要翻译：一种制备分散体的方法，其包括使第一相，与其不混溶的第一材料，第一聚合材料和第二聚合材料接触的步骤，其中：（a）（i）所述第一聚合物材料具有式（I），其中A和B相同或不同，选自任选取代的芳族和非芳族基团，并且至少一个包含相对极性的原子或基团，R 1和R 2 独立地包括相对非极性的原子或基团; （ii）所述第一聚合物材料通过提供通式（I）的化合物来制备或制备，其中A，B，R 1和R 2如上所述在水性溶剂中并使所述化合物中的基团CC彼此反应以形成所述第一聚合物材料; （b）所述第二聚合物材料包括能够与所述第一聚合物材料反应使得在所述第一和第二聚合物材料之间形成共价键的官能团; （c）所述第一聚合物材料的重量与所述第一相重量之比等于或小于0.0025; 和（d）所述第二聚合材料的重量与所述第一相重量之比等于或小于0.035。

3. 发明授权

US07651981B2 Recovering materials 失效
标题翻译：回收材料
公开(公告)号：US07651981B2
公开(公告)日：2010-01-26
申请号：US10509281
申请日：2003-03-28
申请人： Donald Eagland , Nicholas John Crowther , James Murray , Austin Tobin
发明人： Donald Eagland , Nicholas John Crowther , James Murray , Austin Tobin
IPC分类号： C09K8/588
CPC分类号： C09K8/588
摘要： A process for recovering materials from a subterranean formation, for example in enhanced oil recovery, comprises: (A) (a) (i) selecting a first polymeric material having a repeat unit of formula (A) wherein A and B are the same or different, are selected from optionally-substituted aromatic and heteroaromatic groups and at least one comprises a relatively polar atom or group and R1 and R2 independently comprise relatively non-polar atoms or groups; or (ii) selecting a first polymeric material prepared or preparable by providing a compound of general formula (B) wherein A, B, R1 and R2 are as described above, in an aqueous solvent and causing the groups C═C in said compound to react with one another to form said first polymeric material; (b) selecting a second polymeric material which includes a functional group which is able to react in the presence of said first polymeric material to form a third polymeric material; (c) causing the formation of said third polymeric material by a reaction involving said first and second polymeric materials; and (d) contacting the subterranean formation with said third polymeric material; or (B) contacting the formation with a polymeric material (hereinafter “said third polymer material”) which is a product of a reaction involving: (a) a first polymeric material as described in (A) (a) (i) or (ii); and (b) a second polymeric material which includes a functional group which is able to react in the presence of said first polymeric material to form said third polymeric material.
摘要翻译：（A）（a）（i）选择具有式（A）的重复单元的第一聚合物材料，其中A和B相同，或者不同的，选自任选取代的芳族和杂芳族基团，并且至少一个包含相对极性的原子或基团，并且R 1和R 2独立地包含相对非极性的原子或基团; 或者（ii）选择通过在水性溶剂中提供其中A，B，R 1和R 2如上所述的通式（B）的通式（B）的化合物制备或制备的第一聚合物材料，并使所述化合物中的基团CC与彼此形成所述第一聚合物材料; （b）选择第二聚合物材料，其包括能在所述第一聚合物材料存在下反应形成第三聚合物材料的官能团; （c）通过涉及所述第一和第二聚合物材料的反应引起所述第三聚合物材料的形成; 和（d）使所述地层与所述第三聚合物接触; 或（B）使该地层与聚合物材料（以下称为“所述第三聚合物材料”）接触，所述聚合物材料是反应产物，该反应涉及：（a）如（A）（a）（i）或（ ii）; 和（b）第二聚合物材料，其包括能够在所述第一聚合物材料存在下反应以形成所述第三聚合物材料的官能团。

4. 发明申请

US20090095324A1 METHOD OF REMOVING A RESIDUAL MATERIAL FROM A CONDUIT 审中-公开
标题翻译：从管道中移除残留材料的方法
公开(公告)号：US20090095324A1
公开(公告)日：2009-04-16
申请号：US12298660
申请日：2007-04-25
申请人： Nicholas John Crowther , Donald Eagland
发明人： Nicholas John Crowther , Donald Eagland
IPC分类号： B08B9/032
CPC分类号： B08B9/032 , C08J3/246 , C08J2325/18 , C08J2329/04
摘要： An underground cable (2) comprises a housing (4) filled with conductive elements (6) and an insulating oil (12). To remove the insulating oil and prevent contamination, a visco-elastic formulation is prepared, suitably from cross-linked polyvinylalcohol, and introduced into the cable (2). The fluid is forced through the cable whereby it removes insulating oil therefrom.
摘要翻译：地下电缆（2）包括填充有导电元件（6）和绝缘油（12）的壳体（4）。为了除去绝缘油并防止污染，制备适合于交联聚乙烯醇的粘弹性配方，并引入电缆（2）中。流体被迫通过电缆，从而从中去除绝缘油。

5. 发明申请

US20080314415A1 Cleaning Contaminated Materials 审中-公开
标题翻译：清洁污染材料
公开(公告)号：US20080314415A1
公开(公告)日：2008-12-25
申请号：US10574188
申请日：2004-09-28
申请人： Nicholas John Crowther , Donald Eagland
发明人： Nicholas John Crowther , Donald Eagland
IPC分类号： B08B3/08
CPC分类号： E21B21/068 , C09K3/32 , E21B21/066
摘要： Oil contaminated drill cuttings are contacted with an oil soluble surfactant with agitation which causes the hydrophobic moiety of the surfactant to interact with the oil. Next, an aqueous polymer formulation comprising a polymer having polar and/or ionic functionality is added and mixed. Then, an excess volume of water is added with gentle agitation and the mixture is allowed to settle, whereupon the cuttings sediment to the bottom of the receptacle in which the process is undertaken and the supernatant contains a colloidal suspension of particles which comprise oil, surfactant and polymer. The drill cuttings may then be separated from the supernatant by filtration. The supernatant may be treated with a flocculating agent to cause the colloidal particles to sediment. They too may then be separated.
摘要翻译：油污染的钻屑与油溶性表面活性剂在搅拌下接触，这导致表面活性剂的疏水部分与油相互作用。接下来，加入并混合含有具有极性和/或离子官能团的聚合物的含水聚合物制剂。然后，在温和搅拌下加入过量的水，并使混合物沉降，然后将切屑沉积到进行该方法的容器的底部，并且上清液含有包含油，表面活性剂和聚合物。然后可以通过过滤将钻屑与上清液分离。可以用絮凝剂处理上清液，使胶体颗粒沉淀。他们也可以分开。

6. 发明授权

US06660802B2 Polymeric material 失效
公开(公告)号：US06660802B2
公开(公告)日：2003-12-09
申请号：US09820038
申请日：2001-03-28
申请人： Donald Eagland , Nicholas John Crowther
发明人： Donald Eagland , Nicholas John Crowther
IPC分类号： C08F248
CPC分类号： C08G81/02 , C08F2/06 , C08F246/00
摘要： A method of preparing a first polymeric compound which comprises providing a compound of the general formula AR1C═CR2B or a salt thereof where A and B are the same or different and at least on group comprises a relatively polar atom or group and R1 and R2 independently comprise relatively non-polar atoms or groups, in a solvent of a type in which ethane itself is greatly insoluble and spacing the C═C groups in said compound to react with one another to form a polymeric structure. The first polymeric compound may be reacted with a second compound, for example polyvinylalcohol, collagen, or the like to produce a colloid or gel which may have applications in the treatment of burns or recovery of oils.

7. 发明申请

US20130102816A1 METHOD FOR REDUCING THE VISCOSITY OF VISCOUS FLUIDS 审中-公开
标题翻译：降低粘度流体粘度的方法
公开(公告)号：US20130102816A1
公开(公告)日：2013-04-25
申请号：US13446639
申请日：2012-04-13
申请人： Philip Fletcher , Michael John Crabtree , Donald Eagland , Nicholas John Crowther
发明人： Philip Fletcher , Michael John Crabtree , Donald Eagland , Nicholas John Crowther
IPC分类号： C10L10/08
CPC分类号： C10L10/08 , C09K8/588 , C09K8/86 , C10M145/04 , C10M145/08 , C10M145/40 , C10M161/00 , C10M177/00 , C10M2201/02 , C10M2209/04 , C10M2209/062 , C10M2209/10 , C10M2209/12 , C10N2220/00 , C10N2220/142 , C10N2230/02 , F17D1/17 , Y02E60/34 , Y10T137/8593
摘要： A viscous fluid, such as heavy crude oil which is too viscous to enable it to be pumped from a flowing phase of a reservoir into and along a pipeline for delivery to a refinery or other storage facility, may be contacted with a formulation to reduce its viscosity. The formulation comprises a polymeric material AA which includes —O— moieties pendent from a polymeric backbone thereof and said material is optionally cross-linked. In one embodiment, the formulation may comprise polyvinyl alcohol. In an alternative embodiment, the formulation may comprise a cross-linked polymeric material, such as cross-linked polyvinyl alcohol. After the viscous composition has been transported to a desired location, it may be separated from the other components.
摘要翻译：粘稠流体，例如太粘稠以使其能够从管道的流动阶段被泵送到管道中并沿着管道输送到炼油厂或其他储存设施中的重质原油可以与制剂接触以减少其粘度。该制剂包含聚合物材料AA，其包含从其聚合物主链悬挂的-O-部分，并且所述材料任选地是交联的。在一个实施方案中，制剂可以包含聚乙烯醇。在替代实施方案中，制剂可包含交联聚合物材料，例如交联聚乙烯醇。在将粘性组合物输送到所需位置之后，可将其与其它组分分离。

8. 发明授权

US08178586B2 Method for reducing the viscosity of viscous fluids 有权
标题翻译：降低粘性流体粘度的方法
公开(公告)号：US08178586B2
公开(公告)日：2012-05-15
申请号：US12801142
申请日：2010-05-25
申请人： Philip Fletcher , Michael John Crabtree , Donald Eagland , Nicholas John Crowther
发明人： Philip Fletcher , Michael John Crabtree , Donald Eagland , Nicholas John Crowther
IPC分类号： C09K3/00 , C09K8/60
CPC分类号： C10L10/08 , C09K8/588 , C09K8/86 , C10M145/04 , C10M145/08 , C10M145/40 , C10M161/00 , C10M177/00 , C10M2201/02 , C10M2209/04 , C10M2209/062 , C10M2209/10 , C10M2209/12 , C10N2220/00 , C10N2220/142 , C10N2230/02 , F17D1/17 , Y02E60/34 , Y10T137/8593
摘要： A viscous fluid, such as heavy crude oil which is too viscous to enable it to be pumped from a flowing phase of a reservoir into and along a pipeline for delivery to a refinery or other storage facility, may be contacted with a formulation to reduce its viscosity. The formulation comprises a polymeric material AA which includes —O—moieties pendent from a polymeric backbone thereof and said material is optionally cross-linked. In one embodiment, the formulation may comprise polyvinyl alcohol. In an alternative embodiment, the formulation may comprise a cross-linked polymeric material, such as cross-linked polyvinyl alcohol. After the viscous composition has been transported to a desired location, it may be separated from the other components.
摘要翻译：粘稠流体，例如太粘稠以使其能够从管道的流动相被泵送到管道中并沿着管道输送到炼油厂或其他储存设施的粘稠流体可以与制剂接触以减少其粘度。该制剂包含聚合物材料AA，其包含从其聚合物主链悬挂的-O-部分，并且所述材料任选地是交联的。在一个实施方案中，制剂可以包含聚乙烯醇。在替代实施方案中，制剂可包含交联聚合物材料，例如交联聚乙烯醇。在将粘性组合物输送到所需位置之后，可将其与其它组分分离。

9. 发明申请

US20110152212A1 Aqueous Formulations 审中-公开
标题翻译：水性配方
公开(公告)号：US20110152212A1
公开(公告)日：2011-06-23
申请号：US12528375
申请日：2008-02-22
申请人： Nicholas John Crowther , Donald Eagland
发明人： Nicholas John Crowther , Donald Eagland
IPC分类号： A61K31/704 , A61K31/58 , A61K31/65 , A61K31/05 , A61K31/4164 , A61P31/10 , A61P31/04 , A61P35/00 , A61P17/10
CPC分类号： A61K9/0078 , A61K47/32
摘要： A method of preparing an aqueous formulation of an active material and such a formulation per se are described, wherein the active material has a very low solubility in water. The method may involve contacting active material in solid form with an optionally cross-linked water soluble polymer. The water soluble polymer is preferably a polyvinyl polymer with polyvinylalcohol being preferred. The polymer is optionally cross-linked. The method and formulation may be of particular utility in delivery of anti-cancer drugs or drugs via a pulmonary route.
摘要翻译：描述了制备活性材料和这种制剂本身的水性制剂的方法，其中活性材料在水中的溶解度非常低。该方法可以包括使固体形式的活性材料与任选交联的水溶性聚合物接触。水溶性聚合物优选为具有优选聚乙烯醇的聚乙烯基聚合物。聚合物任选地是交联的。该方法和制剂可以特别适用于通过肺途径递送抗癌药物或药物。

10. 发明申请

US20100234253A1 Method for reducing the viscosity of viscous fluids 有权
标题翻译：降低粘性流体粘度的方法
公开(公告)号：US20100234253A1
公开(公告)日：2010-09-16
申请号：US12801142
申请日：2010-05-25
申请人： Philip Fletcher , Michael John Crabtree , Donald Eagland , Nicholas John Crowther
发明人： Philip Fletcher , Michael John Crabtree , Donald Eagland , Nicholas John Crowther
IPC分类号： C09K8/588 , C08F116/06
CPC分类号： C10L10/08 , C09K8/588 , C09K8/86 , C10M145/04 , C10M145/08 , C10M145/40 , C10M161/00 , C10M177/00 , C10M2201/02 , C10M2209/04 , C10M2209/062 , C10M2209/10 , C10M2209/12 , C10N2220/00 , C10N2220/142 , C10N2230/02 , F17D1/17 , Y02E60/34 , Y10T137/8593
摘要： A viscous fluid, such as heavy crude oil which is too viscous to enable it to be pumped from a flowing phase of a reservoir into and along a pipeline for delivery to a refinery or other storage facility, may be contacted with a formulation to reduce its viscosity. The formulation comprises a polymeric material AA which includes —O— moieties pendent from a polymeric backbone thereof and said material is optionally cross-linked. In one embodiment, the formulation may comprise polyvinyl alcohol. In an alternative embodiment, the formulation may comprise a cross-linked polymeric material, such as cross-linked polyvinyl alcohol. After the viscous composition has been transported to a desired location, it may be separated from the other components.
摘要翻译：粘稠流体，例如太粘稠以使其能够从管道的流动阶段被泵送到管道中并沿着管道输送到炼油厂或其他储存设施中的重质原油可以与制剂接触以减少其粘度。该制剂包含聚合物材料AA，其包含从其聚合物主链悬挂的-O-部分，并且所述材料任选地是交联的。在一个实施方案中，制剂可以包含聚乙烯醇。在替代实施方案中，制剂可包含交联聚合物材料，例如交联聚乙烯醇。在将粘性组合物输送到所需位置之后，可将其与其它组分分离。

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