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1. 发明申请

US20170304630A1 IMPLANTABLE ASSEMBLY 审中-公开
公开(公告)号：US20170304630A1
公开(公告)日：2017-10-26
申请号：US15517922
申请日：2015-10-07
申请人： Neuroloop GmbH
发明人： Dennis PLACHTA , Mortimer GIEHRTMUEHLEN , Thomas STIEGLITZ , Josef ZENTNER
IPC分类号： A61N1/36 , A61N1/378 , A61N1/372 , A61N1/05
摘要： An implantable assembly is described for acquisition of neuronal electrical signals at a selected location which propagate along at least one nerve fiber contained in a nerve fiber bundle, as well as for selective electrical stimulation of the at least one nerve fiber, having: an implantable electrode assembly (E) which is disposed on a biocompatible support substrate which can be positioned around the nerve fiber bundle in a cuff, which has a cylindrical support substrate surface (i) which in the implanted condition is orientated facing the nerve fiber bundle, on which a first electrode assembly for locationally selective acquisition of the neuronal electrical signals and selective electrical stimulation of the at least one nerve fiber, and on which a second electrode assembly is disposed to record an ECG signal, and an analysis and control unit (A/S) which can be electrically conductively connected or is connected to the implantable electrode assembly (E), in which the locationally selective acquired neuronal electrical signals as well as the ECG signal can be analyzed in a time-resolved manner such that a neuronal time signal correlated with a physiological parameter, such as blood pressure, can be derived.

2. 发明申请

US20210161381A1 MEDICAL IMPLANT, ASSEMBLY FOR IMPLANTING THE MEDICAL IMPLANT AND ASSEMBLY FOR DETECTING AN INTRACORPOREAL MOVEMENT PATTERN WITH THE MEDICAL IMPLANT 有权
公开(公告)号：US20210161381A1
公开(公告)日：2021-06-03
申请号：US17252150
申请日：2019-06-13
申请人： Neuroloop GmbH
发明人： Dennis PLACHTA
IPC分类号： A61B5/00 , A61B5/07 , G06K19/07 , G06K7/10
摘要： Described is a medical implant with a structure which is made of at least one biocompatible material, can be converted from a first spatially compact state into a second spatially deployed and flexible deformable state, has an modulus of elasticity that corresponds to the wall of a blood vessel in an order of magnitude between 105 N m−2 and 107 N m−2, has at least one region with an acoustic impedance of more than 1.63·106 kg/m2s, and in the second state has an effective operating surface that is flexibly deformable and at least partially reflects ultrasonic waves. In addition, an assembly is described for detecting an intracorporeal movement pattern using the medical implant that has a sonography device, which is positioned extracorporeally such that ultrasonic waves which are generated by the sonographic device and which strike the effective operating surface of the intracorporeally applied medical implant and are partially reflected thereon can be used to detect changes in the spatial distance between the effective operating surface and the sonography device.

3. 发明公开

US20240099629A1 Device and Method for Detecting a Medically Active Implant Within a Person 审中-公开
公开(公告)号：US20240099629A1
公开(公告)日：2024-03-28
申请号：US17769094
申请日：2020-09-24
申请人： Neuroloop GmbH
发明人： Dennis PLACHTA , Nils KÖNNE
IPC分类号： A61B5/28 , A61B5/251 , A61B5/347 , A61N1/37
CPC分类号： A61B5/28 , A61B5/251 , A61B5/347 , A61N1/3704 , A61N1/3706
摘要： The invention is a device and a method for detecting a medically active implant capable of electrical stimulation implanted within a person. Moreover, the invention also relates to the use of the device for determining the operational status of the medically active implant. The device is characterized by components: a) at least two electrodes that are in, or can be brought into, contact with the person, b) an electrical voltage measuring unit which is electrically connected to the at least two electrodes and which is capable of generating electrical voltage timing signals and c) an evaluation unit which is connected to the electrical voltage measuring unit.

4. 发明申请

US20210162208A1 DEVICE FOR EXTRAVASAL OR EXTRANEURONAL FASTENING OF A MEDICAL IMPLANT IN THE MANNER OF A COMPRESSION SLEEVE 有权
公开(公告)号：US20210162208A1
公开(公告)日：2021-06-03
申请号：US17056345
申请日：2019-05-07
申请人： Neuroloop GmbH
发明人： Dennis PLACHTA , Tim BORETIUS , Fabian KIMMIG , Christina HASSLER
IPC分类号： A61N1/05
摘要： A device for the extravasal or extraneuronal fastening of a medical implant has a biocompatible surface substrate having a first substrate portion which is a compression sleeve and has a free end portion which by winding the first substrate portion about a spatial axis which is loosely radially covered in at least one layer by the wound first substrate portion. A second substrate portion which is attached integrally to the first substrate portion which is not wound about the spatial axis and is with a connection extending away from the medical implant.

5. 发明申请

US20200147394A1 IMPLANTABLE ASSEMBLY 审中-公开
公开(公告)号：US20200147394A1
公开(公告)日：2020-05-14
申请号：US16743065
申请日：2020-01-15
申请人： Neuroloop GmbH
发明人： Dennis PLACHTA , Mortimer GIEHRTMUEHLEN , Thomas STIEGLITZ , Josef ZENTNER
IPC分类号： A61N1/36 , A61N1/378 , A61N1/372
摘要： An implantable assembly is described for acquisition of neuronal electrical signals at a selected location which propagate along at least one nerve fiber contained in a nerve fiber bundle, as well as for selective electrical stimulation of the at least one nerve fiber, having: an implantable electrode assembly (E) which is disposed on a biocompatible support substrate which can be positioned around the nerve fiber bundle in a cuff, which has a cylindrical support substrate surface (i) which in the implanted condition is orientated facing the nerve fiber bundle, on which a first electrode assembly for locationally selective acquisition of the neuronal electrical signals and selective electrical stimulation of the at least one nerve fiber, and on which a second electrode assembly is disposed to record an ECG signal, and an analysis and control unit (A/S) which can be electrically conductively connected or is connected to the implantable electrode assembly (E), in which the locationally selective acquired neuronal electrical signals as well as the ECG signal can be analyzed in a time-resolved manner such that a neuronal time signal correlated with a physiological parameter, such as blood pressure, can be derived.

6. 发明申请

US20210282660A1 Device for Locating a Medical Implant 有权
公开(公告)号：US20210282660A1
公开(公告)日：2021-09-16
申请号：US17258064
申请日：2019-06-26
申请人： Neuroloop GmbH
发明人： Dennis PLACHTA , Tim BORETIUS , Fabian KIMMIG
IPC分类号： A61B5/06 , A61M5/142
摘要： A device is described for the transcutaneous location of an intracorporeally, subcutaneously located medical implant, which has an implant surface on which at least one electrical coil is arranged. The coil has at least one coil winding enclosing a region of the implant surface, together with an extracorporeally operable unit, to which at least one electrical coil is fitted, which is adapted in shape and size to the electrical coil arranged on the implant, and which is connected to an electrical control unit and to a signalling means, which generates a perceptible signal, at least in the case of maximum inductive coupling between the two electrical coils.

7. 发明申请

US20210100507A1 Device for Detecting at Least One Human Vital Parameter by Means of a Sensor 有权
公开(公告)号：US20210100507A1
公开(公告)日：2021-04-08
申请号：US16620667
申请日：2018-05-28
申请人： Neuroloop GmbH
发明人： Fabian KIMMIG , Tim BORETIUS , Dennis PLACHTA
IPC分类号： A61B5/00 , A61B5/0205
摘要： A device for the sensory detection of at least one human vital parameter comprises a support, which is shaped and dimensioned to be at least partly removably placed in the human outer ear canal, and to which at least one sensor for the detection of a vital parameter is attached. The support is a planar substrate, which is a hollow cylinder defining a continuously open hollow channel. A hollow cylindrical outer wall region at least partly contacts a surface of the inner wall of the ear canal when the support is at least partly placed in the human outer ear canal.

8. 发明申请

US20190320921A1 IMPLANTABLE ELECTRIC MULTI-POLE CONNECTION STRUCTURE 审中-公开
公开(公告)号：US20190320921A1
公开(公告)日：2019-10-24
申请号：US16461962
申请日：2017-11-17
申请人： Neuroloop GmbH
发明人： Fabian KIMMIG , Tim BORETIUS , Dennis PLACHTA
IPC分类号： A61B5/04 , A61N1/05 , A61N1/36 , A61N1/375
摘要： The invention relates to an implantable electric multi-pole connection between an electric implant and an electric feed and discharge structure. The invention is characterised in that a flexible, film-like, electrically non-conductive, strip-shaped surface element is arranged between the implant and the feed and discharge structure. The surface element comprises at least one first surface, on which a number of electrodes n greater than of equal to two is arranged, which are respectively connected to the electric implant by means of electric connection conductors extending at least in parts inside the surface element. The electric feed and discharge structure comprises at least n lines which are electrically insulated from each other and which are electrically connected to one of the n electrodes. The strip-shaped surface element is wound around a winding axis, which adopts the shape of a helix, along a cover surface of a virtual cylinder provided with a cylinder axis which is straight or curved at least in sections.

9. 发明申请

US20170326362A1 IMPLANTABLE ELECTRODE CONFIGURATION 审中-公开
公开(公告)号：US20170326362A1
公开(公告)日：2017-11-16
申请号：US15517890
申请日：2015-10-07
申请人： Neuroloop GmbH
发明人： Dennis PLACHTA , Mortimer GIEHRTMUEHLEN , Thomas STIEGLITZ , Josef ZENTNER
IPC分类号： A61N1/36 , A61N1/32 , A61N1/05 , A61N1/372
CPC分类号： A61N1/3605 , A61N1/05 , A61N1/057 , A61N1/059 , A61N1/326 , A61N1/37247
摘要： The invention is an implantable electrode configuration having a carrier substrate of a biocompatible polymer in at least some areas and a freely accessible electrode surface applied to the carrier substrate or integrated into the carrier substrate on the carrier substrate surface in at least some areas is described and a method for producing the implantable electrode configuration. The electrode has a metallic base plate having a planar top side and bottom side, including at least one structural element protruding orthogonally from the top side. The planar surface of the metallic base plate is oriented parallel to the carrier substrate surface and the metallic base plate is enclosed by the biocompatible polymer, except for a first surface area of the at least one structural element which faces the carrier substrate surface and is the freely accessible electrode surface.

10. 发明公开

US20240075281A1 IMPLANTABLE ELECTRODE ARRANGEMENT 审中-公开
公开(公告)号：US20240075281A1
公开(公告)日：2024-03-07
申请号：US18504281
申请日：2023-11-08
申请人： Neuroloop GmbH
发明人： Dennis PLACHTA , Mortimer GIEHRTMUEHLEN , Thomas STIEGLITZ , Josef ZENTNER
IPC分类号： A61N1/05 , A61B5/24
CPC分类号： A61N1/0556 , A61B5/24 , A61B2562/066 , A61B2562/164
摘要： An implantable electrode arrangement provides spatially-selective detection of neuronal electrical signals, which propagate along at least one nerve fiber contained in a nerve fascicle, and for selective electrical stimulation of the at least one nerve fiber, comprising a biocompatible carrier substrate, which has at least one carrier substrate region that can be placed around the nerve fascicle in a cuff and has a straight cylinder-shaped carrier substrate surface which faces the nerve fascicle in the implanted state. The carrier substrate surface has an axial extension and an extension oriented circumferentially in a direction and a first electrode arrangement attached thereto. The electrode arrangement comprises in an axial sequence, at least three first electrode structures with at least two first electrode surfaces arranged in the circumferentially, and at least two spaced first electrode strips, displayed in the axial direction which extend circumferentially which are in a ring shape, which encloses the at least three electrode structures on both sides in the axial direction. The electrodes are connectable or are connected to a signal detector and generator.

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