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    • 4. 发明申请
    • Devices, Systems and Methods for Acute or Chronic Delivery of Substances or Apparatus to Extravascular Treatment Sites
    • 用于急性或慢性输送物质或装置用于血管外治疗部位的装置,系统和方法
    • US20080051756A1
    • 2008-02-28
    • US11927888
    • 2007-10-30
    • Joshua MakowerTheodore LamsonJ. Christopher FlahertyJohn ReggieJohn ChangJoseph CataneseDavid Tholfsen
    • Joshua MakowerTheodore LamsonJ. Christopher FlahertyJohn ReggieJohn ChangJoseph CataneseDavid Tholfsen
    • A61M5/178A61M31/00
    • A61M25/0108A61B6/12A61M5/007A61M25/0084A61M2025/0086A61M2025/0087A61M2025/009A61M2210/12
    • Methods and apparatus for delivery of substances or apparatus to target sites located outside blood vessels within the body of a human or animal patient. A vessel wall penetrating catheter is inserted into the vasculature, positioned and oriented within a blood vessel near the target extravascular site and a penetrator is advanced from the catheter so as to penetrate outwardly through the wall of the blood vessel in the direction of the target site. Thereafter, a delivery catheter is passed through a lumen of the penetrator to the target site. A desired substance or apparatus is then delivered to or obtained from the target site. In some applications, the penetrator may be retracted into the vessel wall penetrating catheter and the vessel wall penetrating catheter may be removed, leaving the delivery catheter in place for chronic or continuous delivery of substance(s) to and/or obtaining of information or samples from the target site. Alternatively, a delivery catheter having an occlusion member or balloon may be advanced into a vein or venule and the occlusion member or balloon may be used to occlude the lumen of the vein or venule during and after injection of a substance through the catheter, such that the substance will not be carried away by normal venous blood flow and will remain in the vein or venule for a sufficient period of time to have its intended effect (e.g. to enter adjacent tissues through capillary beds drained by that vein or venule).
    • 用于将物质或装置输送到位于人或动物患者体内的血管外的位置的方法和装置。 将血管壁穿透导管插入脉管系统中,定位并定向在目标血管外部位附近的血管内,并且穿透器从导管前进,以便沿目标部位的方向向外穿过血管壁 。 此后,输送导管穿过穿透器的内腔到目标部位。 然后将所需的物质或装置输送到目标部位或从目标部位获得。 在一些应用中,穿透器可以缩回到穿过导管的血管壁中,并且可以移除穿透导管的血管壁,使输送导管留在适当位置,以便将物质慢慢地或连续地递送到和/或获得信息或样品 从目标网站。 或者,具有闭塞构件或气囊的输送导管可以推入静脉或小静脉中,并且阻塞构件或气囊可以在通过导管注入物质期间和之后用于闭塞静脉或小静脉的腔,使得 该物质不会被正常的静脉血流带走,并将在静脉或小静脉中保持足够的时间以达到其预期效果(例如,通过由该静脉或小静脉排出的毛细血管床进入相邻组织)。
    • 7. 发明授权
    • Multifunctional spring-grip dumb-bell
    • 多功能弹簧夹哑铃
    • US5519918A
    • 1996-05-28
    • US409073
    • 1995-03-22
    • John Chang
    • John Chang
    • A61H15/00A63B23/16A47B95/02
    • A63B23/16A61H2015/0014Y10S16/12Y10T16/476
    • A multifunctional spring-grip dumb-bell including a fist base frame and a second base frame symmetrically disposed in a diagonal manner, each base frame comprising an axle and a supporting bar extended from one end of the axle at right angles; a first locating member and a second locating member symmetrically disposed in a diagonal manner, each locating member having a first end connected to the axle of the first base frame and a second end linked to the supporting bar of the second base frame; first spring means connected between the supporting bar of the first base frame and the second end of the second locating member; second spring means connected between the supporting bar of the second base frame and the second end of the second locating member; two barrels respectively turned round the axles of the first and second base frames for the holding of the hand; two locking means respectively mounted on the locating members and controlled to lock the barrels in position, prohibiting the barrels from rotary motion relative to the axles of the first and second base frames; and two covers respectively fastened to the locating members by screws.
    • 一种多功能弹簧把手哑铃,其包括以对角方式对称设置的第一基座框架和第二底座框架,每个底座框架包括轴和从所述车轴的一端以直角延伸的支撑杆; 第一定位构件和第二定位构件以对角方式对称地设置,每个定位构件具有连接到第一基架的轴的第一端和连接到第二基架的支撑杆的第二端; 第一弹簧装置,连接在第一基架的支撑杆和第二定位构件的第二端之间; 第二弹簧装置,连接在第二基架的支撑杆和第二定位构件的第二端之间; 两个桶分别转动第一和第二基架的轴用于握持手; 两个锁定装置分别安装在定位构件上并被控制以将筒锁定在适当位置,从而禁止桶相对于第一和第二基架的轴旋转运动; 两个盖子通过螺钉分别固定在定位件上。