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1. 发明授权

US6057102A HIV coreceptor mutants 失效
标题翻译： HIV共同受体突变体
公开(公告)号：US6057102A
公开(公告)日：2000-05-02
申请号：US907468
申请日：1997-08-08
申请人： Nathaniel R. Landau , Richard A. Koup , Rong Liu , William Paxton
发明人： Nathaniel R. Landau , Richard A. Koup , Rong Liu , William Paxton
IPC分类号： C07K14/715 , C12Q1/70 , C12Q1/68
CPC分类号： C12Q1/703 , C07K14/7158 , A01K2217/05 , C12Q2600/156
摘要： Entry of HIV-1 into target cells requires cell surface CD4 as well as additional host cell cofactors. A cofactor required for infection with virus adapted for growth in transformed T cell lines was recently identified and named fusin. Fusin, however, does not promote entry of macrophage-tropic viruses that are believed to be the key pathogenic strains in vivo. It has now been determined that the principal cofactor for entry mediated by the envelope glycoproteins of primary macrophage-tropic strains of HIV-1 is CC-CKR5, a receptor for the .beta.-chemokines RANTES, MIP-1.alpha., and MIP-1.beta.. It has also been found that individuals who are homozygous for a mutation of the CKR-5 receptor are resistent to HIV infection; in vitro infection requires a 1000-fold higher dose of HIV than normal cells. The mutation results in complete suppression of CKR-5 expression.
摘要翻译： HIV-1进入靶细胞需要细胞表面CD4以及额外的宿主细胞辅因子。最近鉴定了一种在转化的T细胞系中适应生长的病毒感染所需的辅因子，并命名为fusin。然而，Fusin不促进被认为是体内关键致病菌株的巨噬细胞 - 嗜性病毒的进入。现在已经确定，由HIV-1的初级巨噬细胞 - 热带菌株的包膜糖蛋白引入的主要辅助因子是CC-CKR5，β-chemokines RANTES，MIP-1α和MIP-1β的受体。还发现对CKR-5受体的突变是纯合的个体对HIV感染是抗性的; 体外感染需要比正常细胞高1000倍的HIV。突变导致CKR-5表达的完全抑制。

2. 发明授权

US5939320A G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof 失效
标题翻译：与巨噬细胞营养性HIV相关的G-偶联受体及其诊断和治疗用途
公开(公告)号：US5939320A
公开(公告)日：1999-08-17
申请号：US666020
申请日：1996-06-19
申请人： Dan R. Littman , Hongkui Deng , Wilfried Ellmeier , Nathaniel R. Landau , Rong Liu
发明人： Dan R. Littman , Hongkui Deng , Wilfried Ellmeier , Nathaniel R. Landau , Rong Liu
IPC分类号： C07K14/715 , C12N15/85 , G01N33/50 , G01N33/569 , C12N5/06 , C12N5/08 , C12N5/10
CPC分类号： G01N33/502 , C07K14/7158 , C12N15/8509 , G01N33/5008 , G01N33/5041 , G01N33/5047 , G01N33/505 , G01N33/5055 , G01N33/5091 , G01N33/56988 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2217/30 , A01K2227/105 , A01K2267/02 , A01K2267/0337 , A01K2267/0393
摘要： Entry of HIV-1 into target cells requires cell surface CD4 as well as additional host cell cofactors. A cofactor required for infection with virus adapted for growth in transformed T cell lines was recently identified and named fusin. Fusin, however, does not promote entry of macrophage-tropic viruses that are believed to be the key pathogenic strains in vivo. It has now been determined that the principal cofactor for entry mediated by the envelope glycoproteins of primary macrophage-tropic strains of HIV-1 is CC-CKR5, a receptor for the .beta.-chemokines RANTES, MIP-1.alpha., and MIP-1.beta..
摘要翻译： HIV-1进入靶细胞需要细胞表面CD4以及额外的宿主细胞辅因子。最近鉴定了一种在转化的T细胞系中适应生长的病毒感染所需的辅因子，并命名为fusin。然而，Fusin不促进被认为是体内关键致病菌株的巨噬细胞 - 嗜性病毒的进入。现在已经确定，由HIV-1的初级巨噬细胞 - 热带菌株的包膜糖蛋白引入的主要辅助因子是CC-CKR5，β-chemokines RANTES，MIP-1α和MIP-1β的受体。

3. 发明授权

US06258527B1 Methods of identifying g-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof 失效
标题翻译：鉴定与巨噬细胞营养型HIV相关的g-偶联受体的方法及其诊断和治疗用途
公开(公告)号：US06258527B1
公开(公告)日：2001-07-10
申请号：US08861105
申请日：1997-05-21
申请人： Dan R. Littman , Hongkui Deng , Wilfried Ellmeier , Nathaniel R. Landau , Rong Liu
发明人： Dan R. Littman , Hongkui Deng , Wilfried Ellmeier , Nathaniel R. Landau , Rong Liu
IPC分类号： C12Q170
CPC分类号： G01N33/56988 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2217/075 , A01K2217/30 , A01K2227/105 , A01K2267/0337 , C07K14/7158 , C12N15/8509 , G01N33/5008 , G01N33/502 , G01N33/5041 , G01N33/5047 , G01N33/505 , G01N33/5055 , G01N33/5091
摘要： Entry of HIV-1 into target cells requires cell surface CD4 as well as additional host cell cofactors. A cofactor required for infection with virus adapted for growth in transformed T cell lines was recently identified and named fusin. Fusin, however, does not promote entry of macrophage-tropic viruses that are believed to be the key pathogenic strains in vivo. It has now been determined that the principal cofactor for entry mediated by the envelope glycoproteins of primary macrophage-tropic strains of HIV-1 is CC-CKR5, a receptor for the &bgr;-chemokines RANTES, MIP-1&agr;, and MIP-1&bgr;.
摘要翻译： HIV-1进入靶细胞需要细胞表面CD4以及额外的宿主细胞辅因子。最近鉴定了一种在转化的T细胞系中适应生长的病毒感染所需的辅因子，并命名为fusin。然而，Fusin不促进被认为是体内关键致病菌株的巨噬细胞 - 嗜性病毒的进入。现在已经确定，由HIV-1的初级巨噬细胞 - 嗜热菌株的包膜糖蛋白介导的进入的主要辅助因子是CC-CKR5，β-趋化因子RANTES，MIP-1α和MIP-1β的受体。

4. 发明授权

US07129055B2 Methods of identifying g-couple receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof 有权
标题翻译：识别与巨噬细胞营养型HIV相关的g-偶合受体的方法及其诊断和治疗用途
公开(公告)号：US07129055B2
公开(公告)日：2006-10-31
申请号：US09734221
申请日：2000-12-11
申请人： Dan R. Littman , Hongkui Deng , Wilfried Ellmeier , Nathaniel R. Landau , Rong Liu
发明人： Dan R. Littman , Hongkui Deng , Wilfried Ellmeier , Nathaniel R. Landau , Rong Liu
IPC分类号： C01N33/53 , C01N33/533 , C12N15/00 , C12N15/48 , C12N15/07 , C12N15/09 , C12N5/28 , C07K16/28
CPC分类号： G01N33/56988 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2217/075 , A01K2217/30 , A01K2227/105 , A01K2267/0337 , C07K14/7158 , C12N15/8509 , G01N33/5008 , G01N33/502 , G01N33/5041 , G01N33/5047 , G01N33/505 , G01N33/5055 , G01N33/5091
摘要： Entry of HIV-1 into target cells requires cell surface CD4 as well as additional host cell cofactors. A cofactor required for infection with virus adapted for growth in transformed T cell lines was recently identified and named fusin. Fusin, however, does not promote entry of macrophage-tropic viruses that are believed to be the key pathogenic strains in vivo. It has now been determined that the principal cofactor for entry mediated by the envelope glycoproteins of primary macrophage-tropic strains of HIV-1 is CC-CKR5, a receptor for the β-chemokines RANTES, MIP-1α, and MIP-1β.
摘要翻译： HIV-1进入靶细胞需要细胞表面CD4以及额外的宿主细胞辅因子。最近鉴定了一种在转化的T细胞系中适应生长的病毒感染所需的辅因子，并命名为fusin。然而，Fusin不促进被认为是体内关键致病菌株的巨噬细胞 - 嗜性病毒的进入。现在已经确定，由HIV-1的初级巨噬细胞 - 嗜热菌株的包膜糖蛋白介导的进入的主要辅助因子是CC-CKR5，β-趋化因子RANTES，MIP-1α和MIP-1β的受体。

5. 发明授权

US08999807B2 Method for manufacturing a semiconductor component that includes a common mode choke and structure 有权
标题翻译：包括共模扼流圈和结构的半导体部件的制造方法
公开(公告)号：US08999807B2
公开(公告)日：2015-04-07
申请号：US12788297
申请日：2010-05-27
申请人： Li Jiang , Ryan J. Hurley , Sudhama C. Shastri , Yenting Wen , Wang-Chang Albert Gu , Phillip Holland , Der Min Liou , Rong Liu , Wenjiang Zeng
发明人： Li Jiang , Ryan J. Hurley , Sudhama C. Shastri , Yenting Wen , Wang-Chang Albert Gu , Phillip Holland , Der Min Liou , Rong Liu , Wenjiang Zeng
IPC分类号： H01L21/20 , H01L21/44 , H01L21/48 , H01L21/50 , H01L23/522 , H01L49/02 , H01L23/66
CPC分类号： H01L23/5227 , H01L23/66 , H01L28/10 , H01L2223/6638 , H01L2224/05554 , H01L2224/48091 , H01L2224/48137 , H01L2224/48247 , H01L2224/49113 , H01L2924/1301 , H01L2924/1305 , H01L2924/13091 , H01L2924/00014 , H01L2924/00
摘要： A semiconductor component and methods for manufacturing the semiconductor component that includes a monolithically integrated common mode choke. In accordance with embodiments, a transient voltage suppression device may be coupled to the monolithically integrated common mode choke.
摘要翻译：一种半导体元件及其制造方法，该半导体元件包括单片集成的共模扼流圈。根据实施例，瞬态电压抑制装置可以耦合到单片集成的共模扼流圈。

6. 发明授权

US08657194B2 Compact hybrid imaging lens assembly in an imaging reader 有权
标题翻译：成像读取器中的紧凑型混合成像透镜组件
公开(公告)号：US08657194B2
公开(公告)日：2014-02-25
申请号：US13175245
申请日：2011-07-01
申请人： Rong Liu , David Tsi-Shi
发明人： Rong Liu , David Tsi-Shi
IPC分类号： G06K7/10
CPC分类号： G06K7/10722 , G06K7/10831
摘要： A compact hybrid imaging lens assembly captures return light from a target over a field of view of a linear array of image sensors of a solid-state imager, and projects the captured return light onto the array during electro-optical reading of the target. The assembly includes a plastic lens for optical aberration correction, a glass lens spaced away from the plastic lens along an optical axis, and an aperture stop between the lenses and having an asymmetrical aperture through which the optical axis extends. The glass lens has substantially all the optical power of the imaging lens assembly for thermal stability, and the plastic lens has substantially no optical power. A holder holds the lenses and the aperture stop away from the array. Alignment elements on the plastic lens align the asymmetrical aperture relative to the linear array.
摘要翻译：紧凑的混合成像透镜组件在固态成像器的图像传感器的线性阵列的视野上捕获来自目标的返回光，并且在目标的电光学读取期间将捕获的返回光投射到阵列上。该组件包括用于光学像差校正的塑料透镜，沿着光轴与塑料透镜间隔开的玻璃透镜，以及透镜之间的孔径光阑，并且具有光轴延伸穿过的不对称孔。玻璃透镜具有用于热稳定性的成像透镜组件的基本上所有光学功率，并且塑料透镜基本上没有光学功率。支架将透镜和孔径光阑保持在远离阵列的位置。塑料透镜上的对准元件相对于线性阵列对准不对称孔。

7. 发明授权

US08430316B2 Imaging-based reader having smart illumination 有权
公开(公告)号：US08430316B2
公开(公告)日：2013-04-30
申请号：US11998764
申请日：2007-11-30
申请人： Rong Liu , Eugene Joseph , Ming Yu
发明人： Rong Liu , Eugene Joseph , Ming Yu
IPC分类号： G06K7/10
CPC分类号： G06K7/10732
摘要： A method and imaging assembly (10) are disclosed adapted for reading a target object comprising a scan engine (48) having a sensor (46), focusing optics (44), and an imager (48). The scan engine includes a field-of-view defining an area to be imaged by the imaging assembly (10). A housing (80) internally lodges the scan engine (48) and an illumination source (36). The illumination source (36) is adapted to project illumination from the housing (80). A boot (30) extends from the housing (80) for shaping the illumination as it passes through the boot to form an illumination pattern from the illumination. The illumination pattern substantially conforms to a geometrical shape of the boot (30) and is adapted to envelope the scan engine field-of-view.

8. 发明申请

US20120080803A1 METHOD OF MANUFACTURING A SEMICONDUCTOR COMPONENT AND STRUCTURE 有权
标题翻译：制造半导体元件和结构的方法
公开(公告)号：US20120080803A1
公开(公告)日：2012-04-05
申请号：US12896416
申请日：2010-10-01
申请人： Phillip Holland , Rong Liu , Umesh Sharma , Der Min Liou , David D. Marreiro , Sudhama C. Shastri
发明人： Phillip Holland , Rong Liu , Umesh Sharma , Der Min Liou , David D. Marreiro , Sudhama C. Shastri
IPC分类号： H01L23/52
CPC分类号： H01L28/10 , H01L23/5227 , H01L23/53223 , H01L23/53238 , H01L23/53252 , H01L2924/0002 , H01L2924/00
摘要： A semiconductor component and methods for manufacturing the semiconductor component that includes a three dimensional helically shaped common mode choke. In accordance with embodiments, a transient voltage suppression device may be coupled to the monolithically integrated common mode choke.
摘要翻译：一种半导体元件及其制造方法，该半导体元件包括三维螺旋状共模扼流圈。根据实施例，瞬态电压抑制装置可以耦合到单片集成的共模扼流圈。

9. 发明授权

US07920591B2 Device and method for implenting dynamic adjustmenting bandwidth of data in a transmission device 有权
标题翻译：用于实现传输设备中数据的动态调整带宽的设备和方法
公开(公告)号：US07920591B2
公开(公告)日：2011-04-05
申请号：US10565468
申请日：2003-12-02
申请人： Qingliang Liu , Chang Zhou , Rong Liu
发明人： Qingliang Liu , Chang Zhou , Rong Liu
IPC分类号： H04J3/16 , H04J3/22
CPC分类号： H04Q11/04 , H04J3/1629 , H04J3/1682 , H04Q2213/13204 , H04Q2213/13216 , H04Q2213/13292 , H04Q2213/13332 , H04Q2213/13337 , H04Q2213/13389 , H04Q2213/13392
摘要： A method and a device for realizing dynamic adjustment of data bandwidth of the invention are disclosed. The method comprises adding a control channel in a PCM trunk link to describe occupancy condition of time slots for current services. The device comprises a control word process circuit, a time slot distribution circuit and a CPU interface circuit, wherein the control word process circuit is designed to complete abstraction and insertion of control information in a control channel of E1/T1 link, the time slot distribution circuit completes separating voice time slots from Ethernet data time slots and rebuilding the data, and the CPU interface circuit implements time slot distribution control. The method and the device can implement dynamic adjustment of Ethernet data bandwidth while ensuring voice services, to make effective use of trunk bandwidth and enhance user's data service bandwidth, without error code and interruption of data service during bandwidth adjustment.
摘要翻译：公开了一种用于实现本发明的数据带宽的动态调整的方法和装置。该方法包括在PCM中继链路中添加控制信道，以描述当前业务的时隙的占用情况。该装置包括控制字处理电路，时隙分配电路和CPU接口电路，其中控制字处理电路被设计为完成控制信息在E1 / T1链路的控制信道中的抽象和插入，时隙分布电路完成了语音时隙与以太网数据时隙的分离和重建，CPU接口电路实现了时隙分配控制。该方法和设备可以在确保语音业务的同时，实现以太网数据带宽的动态调整，有效利用中继带宽，提高用户数据业务带宽，带宽调整时无错误代码和数据业务中断。

10. 发明申请

US20100213258A1 Arrangement for and method of generating uniform distributed line pattern for imaging reader 有权
标题翻译：为成像读取器生成均匀分布线图的布置和方法
公开(公告)号：US20100213258A1
公开(公告)日：2010-08-26
申请号：US12380142
申请日：2009-02-24
申请人： Rong Liu , Vladimir Gurevich
发明人： Rong Liu , Vladimir Gurevich
IPC分类号： G06K7/10
CPC分类号： G06K7/10732
摘要： A module and an arrangement for, as well as a method of, generating a generally uniform distributed line pattern of light on a symbol to be read by image capture, include a light source for generating light along an optical axis in a distribution having different extents along intersecting directions generally perpendicular to the axis, and an optical component for receiving, and for optically modifying, the light from the light source to generate the gene rally uniform distributed line pattern of light on the symbol. The optical component includes a plurality of compound conic elements spaced apart from one another along one of the directions. Each compound conic element has a pair of conic segments for modifying the light along the one direction. A collimating lens modifies the light along the other of the directions. A solid-state imager has an array of image sensors for capturing return light from the symbol over a field of view having different extents along the intersecting directions.
摘要翻译：在通过图像捕获读取的符号上产生大致均匀的分布线型图案的模块和方法包括：用于沿着具有不同程度的分布中的光轴产生光的光源沿着与轴垂直的相交方向，以及光学部件，用于接收来自光源的光并用于光学修饰，以在符号上产生基本均匀分布的线状图案。光学部件包括沿着其中一个方向彼此间隔开的多个复合圆锥元件。每个复合圆锥元件具有一对锥形段，用于沿一个方向修改光。准直透镜沿着另一个方向修改光。固态成像器具有一组图像传感器，用于在沿着相交方向具有不同程度的视场上从符号捕获返回光。

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