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1. 发明授权

US10456534B2 Nasal spray delivery guide 有权
公开(公告)号：US10456534B2
公开(公告)日：2019-10-29
申请号：US14974124
申请日：2015-12-18
申请人： Cornell University , Nasalign LLC
发明人： William Reisacher , Erick B. Berglund , Michael Nelson
IPC分类号： A61M11/00 , A61M15/08 , A61F5/08 , A61M11/08
摘要： A nasal spray delivery guide including a pair of guide elements spaced apart from one another and configured to be at least partially inserted into respective nostrils of a patient, and a flexible connector element attached to and extending between the guide elements. Each guide element includes an aperture extending therethrough from a base end to a tip end of the guide element. A method for delivering a nasal spray into a patient's nose includes the steps of providing the nasal spray delivery guide, inserting the guide elements at least partially into respective nostrils of the patient, inserting at least a portion of a nasal spray delivery device into one of the guide elements, and activating the nasal spray delivery device to deliver a nasal spray to a lateral wall of the respective nasal cavity.

2. 发明申请

US20160101243A1 Nasal Spray Delivery Guide 审中-公开
标题翻译：鼻喷雾输送指南
公开(公告)号：US20160101243A1
公开(公告)日：2016-04-14
申请号：US14974124
申请日：2015-12-18
申请人： Nasalign LLC , Cornell University
发明人： William Reisacher , Erick B. Berglund , Michael Nelson
IPC分类号： A61M11/00
CPC分类号： A61M11/00 , A61F5/08 , A61M11/08 , A61M15/085 , A61M2209/088
摘要： A nasal spray delivery guide including a pair of guide elements spaced apart from one another and configured to be at least partially inserted into respective nostrils of a patient, and a flexible connector element attached to and extending between the guide elements. Each guide element includes an aperture extending therethrough from a base end to a tip end of the guide element. A method for delivering a nasal spray into a patient's nose includes the steps of providing the nasal spray delivery guide, inserting the guide elements at least partially into respective nostrils of the patient, inserting at least a portion of a nasal spray delivery device into one of the guide elements, and activating the nasal spray delivery device to deliver a nasal spray to a lateral wall of the respective nasal cavity.
摘要翻译：一种鼻喷雾输送引导件，其包括彼此间隔开并构造成至少部分地插入到患者的相应鼻孔中的一对引导元件，以及附接到引导元件之间并在引导元件之间延伸的柔性连接器元件。每个引导元件包括从引导元件的基端延伸穿过其中的孔。将鼻喷雾器递送到患者鼻部的方法包括以下步骤：提供鼻喷雾输送引导件，将引导元件至少部分地插入患者的相应鼻孔中，将至少一部分鼻喷雾输送装置插入引导元件，以及激活鼻喷雾递送装置以将鼻喷雾物递送到相应鼻腔的侧壁。

3. 发明授权

US11782063B2 Methods for detecting antibodies in mucosal samples and device for sampling mucosal material 有权
公开(公告)号：US11782063B2
公开(公告)日：2023-10-10
申请号：US16373765
申请日：2019-04-03
申请人： Cornell University
发明人： William Reisacher
IPC分类号： G01N33/68 , A61B10/02
CPC分类号： G01N33/6854 , A61B10/02 , A61B2010/0208 , A61B2010/0216 , G01N2800/24
摘要： A method to detect local antibodies such as antigen-specific IgE via a brush biopsy specimen of a mucosal surface of a subject is disclosed. The method is easily performed in an office setting on both adult and pediatric patients. Also disclosed is a brush device specially designed for harvesting materials from a mucosal surface such as the medial surface of the inferior turbinate.

4. 发明授权

US10288621B2 Methods for detecting antibodies in mucosal samples and device for sampling mucosal material 有权
公开(公告)号：US10288621B2
公开(公告)日：2019-05-14
申请号：US14644806
申请日：2015-03-11
申请人： Cornell University
发明人： William Reisacher
IPC分类号： G01N33/68 , A61B10/02
摘要： A method to detect local antibodies such as antigen-specific IgE via a brush biopsy specimen of a mucosal surface of a subject is disclosed. The method is easily performed in an office setting on both adult and pediatric patients. Also disclosed is a brush device specially designed for harvesting materials from a mucosal surface such as the medial surface of the inferior turbinate.

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