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1. 发明申请

US20070141137A1 Stable capsule preparation 审中-公开
标题翻译：稳定胶囊制剂
公开(公告)号：US20070141137A1
公开(公告)日：2007-06-21
申请号：US10591164
申请日：2005-03-03
申请人： Naoki Nagahara , Hiroki Ito , Muneo Nonomura
发明人： Naoki Nagahara , Hiroki Ito , Muneo Nonomura
IPC分类号： A61K31/4439 , A61K9/48
CPC分类号： A61K47/36 , A61K9/4816 , A61K9/4825 , A61K31/4439 , A61K47/42
摘要： A capsule in which an unstable active ingredient has been stabilized is obtained by lowering the moisture content of a solid preparation (granules, subtilis, tablets, etc.) containing a chemical unstable to moisture such as an imidazole PPI compound by drying or the like, and then filling in a capsule comprising a water-soluble polysaccharide such as pullulan as the main component or a PEG-containing gelatin capsule. For the further stabilization, the capsule per se may be dried. The capsule preparation thus obtained is a stable capsule preparation with the use of a capsule being stable at a low moisture content which contains a chemical unstable to moisture such as an imidazole compound.
摘要翻译：通过干燥等降低含有对水分不稳定的化合物的固体制剂（颗粒，枯草芽孢，片剂等）的含水量，使稳定的活性成分稳定化的胶囊得到，然后填充包含水溶性多糖如支链淀粉作为主要成分的胶囊或含PEG的明胶胶囊。为了进一步的稳定化，胶囊本身可以被干燥。由此获得的胶囊制剂是稳定的胶囊制剂，其使用的胶囊以低水分含量稳定，其含有对水分不稳定的化学药剂，例如咪唑化合物。

2. 发明授权

US08697094B2 Stable solid preparations 有权
标题翻译：稳固的固体制剂
公开(公告)号：US08697094B2
公开(公告)日：2014-04-15
申请号：US10530785
申请日：2003-10-15
申请人： Muneo Nonomura , Hiroki Ito , Hideo Hashimoto , Tadashi Urai
发明人： Muneo Nonomura , Hiroki Ito , Hideo Hashimoto , Tadashi Urai
IPC分类号： A61K9/00 , A61K31/44
CPC分类号： A61K9/1676 , A61K9/209 , A61K9/4808 , A61K31/4439 , A61K47/02
摘要： It is intended to provide a process for producing unstable amorphous benzimidazole compounds having a proton pump inhibitor function, and stable solid preparations for medicinal use containing these compounds which are produced by blending such an amorphous benzimidazole compound with a nontoxic base such as a basic inorganic salt, forming an intermediate coating layer on the layer containing the active ingredient and further forming an enteric coating layer or a release-controlling coating layer.
摘要翻译：旨在提供一种制备具有质子泵抑制剂功能的不稳定无定形苯并咪唑化合物的方法，以及含有这些化合物的稳定的固体制剂，其通过将无定形苯并咪唑化合物与无毒碱如碱性无机盐在包含活性成分的层上形成中间涂层，并进一步形成肠溶衣层或释放控制涂层。

3. 发明申请

US20110020410A1 STABLE SOLID PREPARATIONS 有权
标题翻译：稳定的固体制剂
公开(公告)号：US20110020410A1
公开(公告)日：2011-01-27
申请号：US12821717
申请日：2010-06-23
申请人： Muneo Nonomura , Hiroki Ito , Hideo Hashimoto , Tadashi Urai
发明人： Muneo Nonomura , Hiroki Ito , Hideo Hashimoto , Tadashi Urai
IPC分类号： A61K31/4439 , A61K31/4184 , A61K9/00
CPC分类号： A61K9/1676 , A61K9/209 , A61K9/4808 , A61K31/4439 , A61K47/02
摘要： It is intended to provide a process for producing unstable amorphous benzimidazole compounds having a proton pump inhibitor function, and stable solid preparations for medicinal use containing these compounds which are produced by blending such an amorphous benzimidazole compound with a nontoxic base such as a basic inorganic salt, forming an intermediate coating layer on the layer containing the active ingredient and further forming an enteric coating layer or a release-controlling coating layer.
摘要翻译：旨在提供一种制备具有质子泵抑制剂功能的不稳定无定形苯并咪唑化合物的方法，以及含有这些化合物的稳定的固体制剂，其通过将无定形苯并咪唑化合物与无毒碱如碱性无机盐在包含活性成分的层上形成中间涂层，并进一步形成肠溶衣层或释放控制涂层。

4. 发明申请

US20060057195A1 Stable solid preparations 有权
标题翻译：稳固的固体制剂
公开(公告)号：US20060057195A1
公开(公告)日：2006-03-16
申请号：US10530785
申请日：2003-10-15
申请人： Muneo Nonomura , Hiroki Ito , Hideo Hashimoto , Tadashi Urai
发明人： Muneo Nonomura , Hiroki Ito , Hideo Hashimoto , Tadashi Urai
IPC分类号： A61K9/20 , A61K31/4439
CPC分类号： A61K9/1676 , A61K9/209 , A61K9/4808 , A61K31/4439 , A61K47/02
摘要： It is intended to provide a process for producing unstable amorphous benzimidazole compounds having a proton pump inhibitor function, and stable solid preparations for medicinal use containing these compounds which are produced by blending such an amorphous benzimidazole compound with a nontoxic base such as a basic inorganic salt, forming an intermediate coating layer on the layer containing the active ingredient and further forming an enteric coating layer or a release-controlling coating layer.
摘要翻译：旨在提供一种制备具有质子泵抑制剂功能的不稳定无定形苯并咪唑化合物的方法，以及含有这些化合物的稳定的固体制剂，其通过将无定形苯并咪唑化合物与无毒碱如碱性无机盐在包含活性成分的层上形成中间涂层，并进一步形成肠溶衣层或释放控制涂层。

5. 发明授权

US08697097B2 Stable solid preparations 有权
公开(公告)号：US08697097B2
公开(公告)日：2014-04-15
申请号：US12821717
申请日：2010-06-23
申请人： Muneo Nonomura , Hiroki Ito , Hideo Hashimoto , Tadashi Urai
发明人： Muneo Nonomura , Hiroki Ito , Hideo Hashimoto , Tadashi Urai
IPC分类号： A61K47/10 , A61K31/415 , A61K31/44
CPC分类号： A61K9/1676 , A61K9/209 , A61K9/4808 , A61K31/4439 , A61K47/02
摘要： It is intended to provide a process for producing unstable amorphous benzimidazole compounds having a proton pump inhibitor function, and stable solid preparations for medicinal use containing these compounds which are produced by blending such an amorphous benzimidazole compound with a nontoxic base such as a basic inorganic salt, forming an intermediate coating layer on the layer containing the active ingredient and further forming an enteric coating layer or a release-controlling coating layer.

6. 发明授权

US09413157B2 Direct-current circuit breaker 有权
标题翻译：直流断路器
公开(公告)号：US09413157B2
公开(公告)日：2016-08-09
申请号：US14383221
申请日：2012-05-01
申请人： Kazuyori Tahata , Hiroki Ito , Kunio Kikuchi , Kenji Kamei , Yusaku Horinouchi , Masaki Hiratsuka , Sho Tokoyoda , Toshinobu Takeda
发明人： Kazuyori Tahata , Hiroki Ito , Kunio Kikuchi , Kenji Kamei , Yusaku Horinouchi , Masaki Hiratsuka , Sho Tokoyoda , Toshinobu Takeda
IPC分类号： H01H33/59 , H02H3/02 , H02H3/087 , H03K17/13 , H01H9/56
CPC分类号： H02H3/021 , H01H9/56 , H01H33/596 , H02H3/087 , H03K17/13
摘要： A direct-current circuit breaker includes a switching unit inserted in the direct-current line; and a commutation circuit that includes a series circuit including a first current-limiting element and an interrupting unit that forms a current zero point by superimposing a resonance current on a direct current flowing in the direct-current line and interrupts the direct current at the current zero point, that is connected in parallel with the switching unit, and that becomes a flow path for the direct current after the switching unit is opened, wherein current interruption is performed by the interrupting unit after the switching unit is opened.
摘要翻译：直流断路器包括插入直流线路中的开关单元; 以及换向电路，其包括串联电路，该串联电路包括第一限流元件和中断单元，该中断单元通过将谐振电流叠加在流过直流线路的直流电流上而中断当前的直流电流而形成电流零点零点，其与开关单元并联连接，并且在切换单元打开之后成为直流电流的流路，其中在切换单元打开之后由中断单元执行电流中断。

7. 发明申请

US20150043120A1 DIRECT-CURRENT CIRCUIT BREAKER 有权
标题翻译：直流电路断路器
公开(公告)号：US20150043120A1
公开(公告)日：2015-02-12
申请号：US14383221
申请日：2012-05-01
申请人： Kazuyori Tahata , Hiroki Ito , Kunio Kikuchi , Kenji Kamei , Yusaku Horinouchi , Masaki Hiratsuka , Sho Tokoyoda , Toshinobu Takeda
发明人： Kazuyori Tahata , Hiroki Ito , Kunio Kikuchi , Kenji Kamei , Yusaku Horinouchi , Masaki Hiratsuka , Sho Tokoyoda , Toshinobu Takeda
IPC分类号： H02H3/02 , H02H3/087
CPC分类号： H02H3/021 , H01H9/56 , H01H33/596 , H02H3/087 , H03K17/13
摘要： A direct-current circuit breaker includes a switching unit inserted in the direct-current line; and a commutation circuit that includes a series circuit including a first current-limiting element and an interrupting unit that forms a current zero point by superimposing a resonance current on a direct current flowing in the direct-current line and interrupts the direct current at the current zero point, that is connected in parallel with the switching unit, and that becomes a flow path for the direct current after the switching unit is opened, wherein current interruption is performed by the interrupting unit after the switching unit is opened.
摘要翻译：直流断路器包括插入直流线路中的开关单元; 以及换向电路，其包括串联电路，该串联电路包括第一限流元件和中断单元，该中断单元通过将谐振电流叠加在流过直流线路的直流电流上而中断当前的直流电流而形成电流零点零点，其与开关单元并联连接，并且在切换单元打开之后成为直流电流的流路，其中在切换单元打开之后由中断单元执行电流中断。

8. 发明申请

US20140002912A1 LENS DRIVE DEVICE AND IMAGING DEVICE 审中-公开
标题翻译：镜头驱动装置和成像装置
公开(公告)号：US20140002912A1
公开(公告)日：2014-01-02
申请号：US13982342
申请日：2012-01-31
申请人： Takuma Ishikawa , Hiroki Ito , Yohsuke Ikeda , Takafumi Ishikawa , Hiroyuki Watanabe
发明人： Takuma Ishikawa , Hiroki Ito , Yohsuke Ikeda , Takafumi Ishikawa , Hiroyuki Watanabe
IPC分类号： G02B7/02
CPC分类号： G02B7/023 , G02B7/102 , G02B13/009 , G03B3/02 , G03B3/10 , G03B5/00 , G03B17/17 , G03B2205/0046 , G03B2205/0069
摘要： The present invention provides a lens drive device including a base, a lens frame holding a lens and provided to be movable with respect to the base in an optical axis direction of the lens, a light bending portion for bending incident light on the lens, a driving unit for moving the lens frame, and a position detection unit for detecting a position of the lens frame. The position detection unit includes a reflection portion provided to one of the base and the lens frame and including a reflection surface inclined with respect to the optical axis of the lens, and a photoreflector provided to the other of the base and the lens frame and including a light projecting portion applying light to the reflection surface and a light receiving portion receiving light reflected on the reflection surface.
摘要翻译：本发明提供了一种透镜驱动装置，包括：基座，保持透镜的透镜框，设置成能够在透镜的光轴方向上相对于基座移动，用于将入射光弯曲在透镜上的光弯曲部，驱动单元，用于移动透镜框;以及位置检测单元，用于检测透镜框的位置。所述位置检测单元包括设置在所述基座和所述透镜框架中的一个的反射部分，并且包括相对于所述透镜的光轴倾斜的反射表面，以及设置在所述基座和所述透镜框架中的另一个的光反射器，向反射面施加光的光投射部分和接收在反射表面上反射的光的光接收部分。

9. 发明授权

US08488262B2 Lens driving device 有权
标题翻译：镜头驱动装置
公开(公告)号：US08488262B2
公开(公告)日：2013-07-16
申请号：US13304436
申请日：2011-11-25
申请人： Hiroyuki Watanabe , Hiroki Ito
发明人： Hiroyuki Watanabe , Hiroki Ito
IPC分类号： G02B7/02 , G02B15/14
CPC分类号： G02B7/023 , G02B7/102 , G02B13/001 , H02K41/0356
摘要： In a lens driving device, magnetic attraction plates that are magnetic bodies are disposed on a fixed frame at both ends of a movement region of a movable unit. Therefore, when the movable unit moves in the fixed frame to one side or to the other side in the fixed frame and reaches a position at either end of the fixed frame, magnets on the movable unit are magnetically attracted to the magnetic attraction plates on the fixed frame continuously. As a result, the movable unit can be retained at the position even when the coil becomes de-energized.
摘要翻译：在透镜驱动装置中，作为磁体的磁性吸引板被设置在可动单元的移动区域的两端的固定框架上。因此，当可移动单元在固定框架中移动到固定框架中的一侧或另一侧并到达固定框架的任一端的位置时，可移动单元上的磁体被磁吸引到磁吸引板上固定框架连续。结果，即使当线圈断电时，可移动单元也可以保持在该位置。

10. 发明授权

US08234908B2 Apparatus for determining abnormal combustion in internal combustion engine 有权
标题翻译：用于确定内燃机异常燃烧的装置
公开(公告)号：US08234908B2
公开(公告)日：2012-08-07
申请号：US13000033
申请日：2010-05-28
申请人： Shingo Korenaga , Shigeki Miyashita , Hiroki Ito , Yusuke Saitou , Kouhei Kiyota
发明人： Shingo Korenaga , Shigeki Miyashita , Hiroki Ito , Yusuke Saitou , Kouhei Kiyota
IPC分类号： G01L23/22
CPC分类号： F01M13/023 , F02D41/0025
摘要： An object is to provide an abnormal combustion determining apparatus for an internal combustion engine that can identify a major factor causing an oil to flow into a cylinder. The abnormal combustion determining apparatus for the internal combustion engine that includes a plurality of cylinders detects, for each cylinder, a cylinder in which abnormal combustion has occurred. The cylinder in which the abnormal combustion has occurred, and a history of load applied during an operation are stored in memory. It is determined whether or not the cylinder in which the abnormal combustion has occurred and which is stored in memory, is a specific cylinder. It is determined whether or not load present in the history stored in memory and used prior to the occurrence of the abnormal combustion is higher than a threshold value. Based on a combination of a decision made by the cylinder determining means and a decision made by the load determining means, a major factor causing the oil to flow into the cylinder is identified from among relations established for factors of oil flowing into the cylinder according to the combination of these decisions made.
摘要翻译：本发明的目的是提供一种用于内燃机的异常燃烧确定装置，其能够识别导致油流入气缸的主要因素。包括多个气缸的用于内燃机的异常燃烧确定装置针对每个气缸检测发生异常燃烧的气缸。发生异常燃烧的气缸和操作期间的负载历史被存储在存储器中。确定发生了异常燃烧的气缸是否存储在存储器中是特定气缸。确定存储在存储器中并且在发生异常燃烧之前使用的历史中的负载是否高于阈值。基于由气缸确定装置作出的决定与负荷确定装置的决定的组合，从根据根据下列情况的油流入气缸的因素建立的关系中确定导致油流入气缸的主要因素这些决定的结合。

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