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1. 发明授权

US06522912B1 Ear type thermometer 有权
标题翻译：耳式温度计
公开(公告)号：US06522912B1
公开(公告)日：2003-02-18
申请号：US09674732
申请日：2001-01-16
申请人： Naofumi Nakatani , Keiko Noda , Hirofumi Inui , Kazuko Awaya , Kiyoshi Kanazawa , Hirohisa Imai
发明人： Naofumi Nakatani , Keiko Noda , Hirofumi Inui , Kazuko Awaya , Kiyoshi Kanazawa , Hirohisa Imai
IPC分类号： A61B1000
CPC分类号： G01J5/04 , A61B10/0012 , A61B2010/0019 , G01J5/02 , G01J5/025 , G01J5/026 , G01J5/049 , G01J5/06 , G01J5/08 , G01J5/0834 , G01J5/089 , G01J5/0893 , G01J5/34 , G01J2005/0048 , G01J2005/068
摘要： A themometer for measuring a body temperature by using infrared rays and on the basis of a measuring method in which a measurement error fluctuates depending upon the length of the measuring time including computation time. The measuring time is calculated on the basis of a required measurement error, so that a temperature can be measured in a suitable time corresponding to a required allowable error. A probe is formed of a porous structure so as to improve the heat insulating effect thereof, and an auxiliary adapter is provided to permit the thermometer to be fitted better in the earhole in spite of an individual difference in size thereof with the function of reporting a relative ovulation date based on a desired delivery date also incorporated in the themometer.
摘要翻译：一种用于通过使用红外线测量体温的测量计，并且基于测量误差根据包括计算时间的测量时间的长度而波动的测量方法。基于所需的测量误差来计算测量时间，从而可以在对应于所需允许误差的适当时间内测量温度。探针由多孔结构形成，以提高其隔热效果，并且提供辅助适配器以允许温度计在孔中更好地安装在孔中，尽管其尺寸的个体差异具有报告功能基于期望的交付日期的相对排卵日期也包括在计量表中。

2. 发明授权

US06371925B1 Radiation clinical thermometer 失效
标题翻译：辐射体温计
公开(公告)号：US06371925B1
公开(公告)日：2002-04-16
申请号：US09269530
申请日：1999-05-27
申请人： Hirohisa Imai , Kazunari Nisii , Kiyoshi Kanazawa , Makoto Shibuya , Miki Moriguchi , Naohumi Nakatani , Hirohumi Inui , Kazuko Awaya , Kanzi Nisii , Kazumasa Takada , Motomiti Kato , Hirosi Kobayasi , Kozi Yosimoto , Masanori Nisikawa
发明人： Hirohisa Imai , Kazunari Nisii , Kiyoshi Kanazawa , Makoto Shibuya , Miki Moriguchi , Naohumi Nakatani , Hirohumi Inui , Kazuko Awaya , Kanzi Nisii , Kazumasa Takada , Motomiti Kato , Hirosi Kobayasi , Kozi Yosimoto , Masanori Nisikawa
IPC分类号： A61B500
CPC分类号： G01J5/02 , G01J5/025 , G01J5/026 , G01J5/027 , G01J5/04 , G01J5/046 , G01J5/049 , G01J5/06 , G01J5/08 , G01J5/0806 , G01J5/0815 , G01J5/0834 , G01J5/089 , G01J5/62 , G01J2005/0048 , G01J2005/068
摘要： A radiation thermometer measures temperature of the eardrum. The thermometer comprises a signal processor for calculating a temperature from an output of a light receptor, which receives only the infrared rays radiated directly from the eardrum and/or vicinity of it, and a notification system for notifying the temperature resulted from the calculation. Since the structure does not receive an influence of any radiant heats from other than those of the eardrum and/or vicinity of it, temperature change of a probe does not become a factor of measuring errors, so as to offer an accurate measurement of temperatures. An infrared-receiving element is positioned within a triangle configured by an intersection between a light path and an optical axis, and two image points of hypothetical end points formed by an optical condenser, when viewed in a cross sectional plane including the optical axis of the optical condenser, where (a) the light path is a path that extends from the hypothetical end point to the image point of the hypothetical end point formed by the optical condenser by passing through a rim of the optical condenser on the same side as the hypothetical end point with respect to the optical axis, and (b) the hypothetical end point is a point at which a straight line drawn from the rim of the optical condenser toward the probe in a manner to be tangent to an inner surface of the probe on the same side as the rim of the optical condenser with respect to the optical axis crosses a plane at a tip of the probe.
摘要翻译：辐射温度计测量耳膜的温度。该温度计包括一个信号处理器，用于从光接收器的输出计算温度，该光接收器仅接收从鼓膜和/或其附近辐射的红外线;以及通知系统，用于通知由计算产生的温度。由于该结构不会受到来自鼓膜和/或其附近的任何辐射热的影响，所以探针的温度变化不成为测量误差的因素，以提供精确的温度测量。红外线接收元件位于由光路和光轴之间的交点构成的三角形内，并且在包括光轴的光轴的横截面中观察时，由光学聚光器形成的假想端点的两个图像点光学冷凝器，其中（a）光路是从假想终点延伸到由光学冷凝器形成的假想终点的图像点的路径，其通过与所述光学冷凝器的边缘在同一侧上的假想终点相对于光轴的终点，（b）假想终点是从光学冷凝器的边缘朝向探针以与探针的内表面相切的方式绘制的直线的点与光学冷凝器相对于光轴的边缘相同的一侧与探针的尖端处的平面交叉。

3. 发明授权

US07603282B2 Communication system for information of medical doctor's questions to patients, terminal apparatus for medical doctor and terminal apparatus for patient 有权
标题翻译：医生询问病人通讯系统，病人终端设备及终端设备
公开(公告)号：US07603282B2
公开(公告)日：2009-10-13
申请号：US10058732
申请日：2002-01-30
申请人： Hirohisa Imai , Hiroyoshi Nomura , Kiyoshi Kanazawa , Jinsei Miyazaki , Shunichi Nagamoto
发明人： Hirohisa Imai , Hiroyoshi Nomura , Kiyoshi Kanazawa , Jinsei Miyazaki , Shunichi Nagamoto
IPC分类号： G06Q10/00
CPC分类号： G06Q50/22 , G06F19/00 , G06Q30/02 , G06Q50/24 , Y10S707/99945 , Y10S707/99948
摘要： A communication system for providing information of a medical doctor's questions to patients includes a medical doctor terminal apparatus, a patient terminal apparatus, and a database server apparatus for storing question sets for the medical doctor's questions to patients, where the medical doctor terminal apparatus, patient terminal apparatus and database server apparatus are connected through a communication network. The patient terminal apparatus generates question programs for making inquiries about the medical doctor's questions to patients in accordance with the question sets received from the database server apparatus, displays the questions for the medical doctor's questions to patients by execution of the generated question programs, enters answer data to the displayed questions, transmits the entered answer data to the database server apparatus, and stores the transmitted answer data in the database server apparatus. The medical doctor terminal apparatus receives the stored answer data by accessing the database server apparatus, and displays the received answer data thereon.
摘要翻译：用于向患者提供医生问题信息的通信系统包括医生终端设备，患者终端设备和数据库服务器设备，用于将患者的医生问题的问题集存储到医生终端设备，病人终端装置和数据库服务器装置通过通信网络连接。患者终端装置根据从数据库服务器装置接收到的问题集，向病人询问有关医生的问题的问题程序，通过执行生成的问题程序向患者显示医生问题的问题，进入答案向所显示的问题的数据，将输入的应答数据发送到数据库服务器装置，并将发送的应答数据存储在数据库服务器装置中。医疗医疗终端装置通过访问数据库服务器装置来接收存储的应答数据，并在其上显示所接收的应答数据。

4. 发明申请

US20080172245A1 Communication system for information of medical doctor's questions to patients, terminal apparatus for medical doctor and terminal apparatus for patient 有权
标题翻译：医生询问病人通讯系统，病人终端设备及终端设备
公开(公告)号：US20080172245A1
公开(公告)日：2008-07-17
申请号：US10058732
申请日：2002-01-30
申请人： Hirohisa Imai , Hiroyoshi Nomura , Kiyoshi Kanazawa , Jinsei Miyazaki , Shunichi Nagamoto
发明人： Hirohisa Imai , Hiroyoshi Nomura , Kiyoshi Kanazawa , Jinsei Miyazaki , Shunichi Nagamoto
IPC分类号： G06F17/60
CPC分类号： G06Q50/22 , G06F19/00 , G06Q30/02 , G06Q50/24 , Y10S707/99945 , Y10S707/99948
摘要： A communication system for information of medical doctor's questions to patients includes a terminal apparatus for medical doctor, a terminal apparatus for patient, and a database server apparatus for storing question sets for medical doctor's questions to patients, which are connected through a communication network. The terminal apparatus for patient generates question programs for making inquiries about medical doctor's questions to patients in accordance with the question sets received from the database server apparatus, displays the questions for medical doctor's questions to patients by execution of the generated question programs, enters answer data to the displayed questions, transmits the entered answer data to the database server apparatus, and stores the transmitted answer data in the database server apparatus. The terminal apparatus for medical doctor receives the stored answer data by accessing the database server apparatus, and displays the received answer data thereon.
摘要翻译：用于向患者提供医生问题信息的通信系统包括医疗终端装置，患者终端装置，以及通过通信网络连接的用于存储医生对医生问题的问题集的数据库服务器装置。用于患者的终端装置根据从数据库服务器装置接收的问题集合，向病人询问有关医生问题的问题程序，通过执行生成的问题程序向病人显示医生问题的问题，输入答案数据对所显示的问题，将输入的应答数据发送到数据库服务器装置，并将发送的应答数据存储在数据库服务器装置中。医疗用终端装置通过访问数据库服务器装置来接收存储的应答数据，并在其上显示接收到的应答数据。

5. 发明授权

US5426768A Logic simulation with efficient deadlock avoidance by selectively suspending event data fetch based on element information 失效
标题翻译：通过选择性地暂停基于元素信息的事件数据获取，可以有效地避免死锁的逻辑模拟
公开(公告)号：US5426768A
公开(公告)日：1995-06-20
申请号：US975841
申请日：1992-11-13
申请人： Kiyoshi Kanazawa
发明人： Kiyoshi Kanazawa
IPC分类号： G06F11/25 , G06F17/50 , G06F19/00
CPC分类号： G06F17/5022
摘要： Disclosed is a method for simulating an operation of an event driven logic circuit in response to changes of the signal status of each terminal of all the elements in the logical circuit, based on event data each containing event time indicating when the signal status has changed, status change indicating how the status has changed, an element identifier identifying the element, and a terminal identifier identifying the terminal, the method comprising a simulation time output step for outputting data indicating simulation time which is continuously counted up; a first selection step for selecting the event data whose event time is equal to the simulation time; a second selection step for selecting the event data whose event time is earliest among event data present for all the input terminals of the element corresponding to the event data; a simulation step for generating new event data depending on a change of the signal status of the output terminal of the element corresponding to the event data, based on the event data selected by each selection step; and a control step for suspending the operation in the second selection step based on the event data selected by the second selection step, the suspension being exercised separately for each element.
摘要翻译：公开了一种用于根据事件数据模拟事件驱动逻辑电路的操作的方法，该方法基于事件数据，每个事件数据包含指示信号状态何时改变的事件时间，该逻辑电路中的所有元素的每个终端的信号状态的变化，状态变化指示状态如何变化，标识元素的元素标识符和识别终端的终端标识符，该方法包括：模拟时间输出步骤，用于输出指示连续递增的模拟时间的数据; 用于选择事件时间等于模拟时间的事件数据的第一选择步骤; 第二选择步骤，用于在对应于事件数据的元素的所有输入终端存在的事件数据中选择事件时间最早的事件数据; 基于由每个选择步骤选择的事件数据，根据与事件数据对应的元素的输出端子的信号状态的变化来生成新的事件数据的模拟步骤; 以及控制步骤，用于基于由第二选择步骤选择的事件数据来暂停在第二选择步骤中的操作，对于每个元件分别执行暂停。

6. 发明授权

US5860075A Document data filing apparatus for generating visual attribute values of document data to be filed 失效
标题翻译：用于生成要归档的文档数据的视觉属性值的文件数据归档装置
公开(公告)号：US5860075A
公开(公告)日：1999-01-12
申请号：US544825
申请日：1995-10-18
申请人： Tatsuo Hashizume , Kiyoshi Kanazawa , Hiroyuki Sasaki , Hideo Terai , Masaaki Kobayashi
发明人： Tatsuo Hashizume , Kiyoshi Kanazawa , Hiroyuki Sasaki , Hideo Terai , Masaaki Kobayashi
IPC分类号： G06F17/30
CPC分类号： G06F17/30253 , G06F17/30256 , Y10S707/99936
摘要： A document data filing apparatus automatically selects attribute values indicating visual features of a desired document from the code data of document data inputted. The attribute value generation unit generates attribute values indicating visual features of the document data inputted as coded data from the document data input unit. At this point, the presence or absence of dot data and specific words and characters are judged. The document data storage unit stores the document data in association with its attribute for retrieval. The attribute value designation unit makes an operator designate the attribute value as retrieval key to the document data to be retrieved The readout unit reads the document data corresponding to the designated attribute value from the document data storage unit. The display unit displays the document data. The retrieving technique is applied to a word processor.
摘要翻译：文档数据归档装置根据输入的文档数据的代码数据自动选择表示期望文件的视觉特征的属性值。属性值生成单元生成表示从文档数据输入单元输入的作为编码数据输入的文档数据的视觉特征的属性值。此时，判断是否存在点数据和特定字和字符。文档数据存储单元与其属性相关联地存储文档数据以进行检索。属性值指定单元使操作者将属性值指定为要检索的文档数据的检索键。读出单元从文档数据存储单元读取与指定的属性值相对应的文档数据。显示单元显示文档数据。检索技术被应用于文字处理器。

7. 发明申请

US20120316197A1 USE OF EP4 RECEPTOR ANTAGONISTS IN THE TREATMENT OF IL-23 MEDIATED DISEASES 有权
标题翻译： EP4受体拮抗剂在治疗IL-23介导性疾病中的应用
公开(公告)号：US20120316197A1
公开(公告)日：2012-12-13
申请号：US13580323
申请日：2011-02-22
申请人： Kiyoshi Kanazawa , Kazuhiko Nonomura , Takako Okumura , Shinichi Koizumi
发明人： Kiyoshi Kanazawa , Kazuhiko Nonomura , Takako Okumura , Shinichi Koizumi
IPC分类号： A61K31/437 , C07D235/08 , A61K31/4184 , C07C235/46 , A61K31/195 , C07D405/12 , A61K31/443 , C07D409/12 , A61K31/41 , C07D333/24 , A61K31/381 , C07D213/56 , A61K31/44 , A61P37/00 , A61P37/08 , C07D471/04
CPC分类号： A61K45/06 , A61K31/38 , A61K31/437 , A61K31/44 , A61K31/4412 , A61K31/443 , A61K2300/00
摘要： This invention relates to a compound with EP4 antagonistic activity, or a pharmaceutically acceptable salt with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a pharmaceutical composition for the treatment of immune disease or allergy which comprises a therapeutically effective amount of a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof. Further this invention relates to a method for the treatment of immune disease or allergy in an animal subject including a mammalian subject, which comprises administering to the animal subject including a mammalian subject a compound of the formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明涉及具有EP4拮抗活性的化合物或具有EP4受体拮抗活性的药学上可接受的盐，其可用于治疗免疫疾病或变态反应。本发明还涉及具有EP4受体拮抗活性的式（I），（II），（III），（IV），（Va）或（Vb）或其药学上可接受的盐的化合物，其可用于治疗免疫疾病或过敏。本发明还涉及用于治疗免疫疾病或过敏的药物组合物，其包含治疗有效量的式（I），（II），（III），（IV），（Va）或（Vb），或其药学上可接受的盐。本发明还涉及一种用于治疗包括哺乳动物受试者在内的动物受试者的免疫疾病或变态反应的方法，该方法包括向包括哺乳动物受试者的动物受试者施用式（I），（II），（III ），（IV），（Va）或（Vb），或其药学上可接受的盐。

8. 发明授权

US5053980A Method and apparatus for logic simulation 失效
标题翻译：用于逻辑仿真的方法和装置
公开(公告)号：US5053980A
公开(公告)日：1991-10-01
申请号：US319430
申请日：1989-03-06
申请人： Kiyoshi Kanazawa
发明人： Kiyoshi Kanazawa
IPC分类号： G06F11/25 , G06F17/50 , G06F19/00
CPC分类号： G06F17/5022
摘要： Determination of an operation of a logic circuit is usually called logic simulation. The logic simulation in which changes in signal status at input terminals and output terminals of an element in the logic circuit to be simulated are represented by events and the signal status at the output terminal is calculated only for the element in which the event has occurred at the input terminal thereof, is called an event driven logic simulation. In the event driven logic simulation, a current time is used to decide and extract the event to be processed. In the prior art apparatus, the decision and extraction are interrupted when the current time is updated. In the present invention, identifiers (colors) are imparted to the events to group the events. The current time is updated when the event having a special color is not present. Thus, a simulation speed in the event driven logic simulation method and apparatus is improved.

9. 发明授权

US5018089A Logic simulation method and apparatus 失效
标题翻译：逻辑仿真方法及装置
公开(公告)号：US5018089A
公开(公告)日：1991-05-21
申请号：US319319
申请日：1989-03-06
申请人： Kiyoshi Kanazawa
发明人： Kiyoshi Kanazawa
IPC分类号： G06F11/25 , G06F17/50 , G06F19/00
CPC分类号： G06F17/5022
摘要： Determining the operation of a logic circuit through calculation is generally called logic simulation. Especially, in event driven type logic simulation, signal status changes at input and output terminals of an element of the logic circuit are deemed as events and only for an element in which an event occurs at its input terminal, the signal status at its output terminal is calculated. In the event driven type logic simulation, a series of signal status changes externally applied to the logic circuit is stored, as injection events, in a memory of a logic simulation apparatus. If injection events are all stored in the memory before execution of the simulation or injection events are stored in the memory by temporarily stopping the simulation after start thereof, most of memory capacity is consumed by the injection events or simulation speed is degraded. To solve this problem, an identifier (called color) is added to an event and when an injection event is injected, the injected event is associated with auxiliary time representing a minimum of values of event times of injection events expected to be injected after injection of that injected event. Color and auxiliary time are used to permit execution of the simulation in parallel with injection of injection events.

10. 发明授权

US09457084B2 Use of EP4 receptor antagonists in the treatment of IL-23 mediated diseases 有权
标题翻译：使用EP4受体拮抗剂治疗IL-23介导的疾病
公开(公告)号：US09457084B2
公开(公告)日：2016-10-04
申请号：US13580323
申请日：2011-02-22
申请人： Kiyoshi Kanazawa , Kazuhiko Nonomura , Takako Okumura , Shinichi Koizumi
发明人： Kiyoshi Kanazawa , Kazuhiko Nonomura , Takako Okumura , Shinichi Koizumi
IPC分类号： A01N43/42 , A61K31/44 , A01N37/12 , A01N47/28 , A61K31/17 , C07D513/02 , C07D515/02 , C07D211/72 , A61K45/06 , A61K31/38 , A61K31/437 , A61K31/4412 , A61K31/443
CPC分类号： A61K45/06 , A61K31/38 , A61K31/437 , A61K31/44 , A61K31/4412 , A61K31/443 , A61K2300/00
摘要： This invention relates to a compound with EP4 antagonistic activity, or a pharmaceutically acceptable salt with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a pharmaceutical composition for the treatment of immune disease or allergy which comprises a therapeutically effective amount of a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof. Further this invention relates to a method for the treatment of immune disease or allergy in an animal subject including a mammalian subject, which comprises administering to the animal subject including a mammalian subject a compound of the formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof.

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