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1. 发明申请

US20080220181A1 Method of loading a nanotube structure and loaded nanotube structure 审中-公开
标题翻译：加载纳米管结构和负载纳米管结构的方法
公开(公告)号：US20080220181A1
公开(公告)日：2008-09-11
申请号：US11895370
申请日：2007-08-24
申请人： Nadarajan S. Babu , Elisabeth S. Papazoglou , Peter D. Katsikis
发明人： Nadarajan S. Babu , Elisabeth S. Papazoglou , Peter D. Katsikis
IPC分类号： B05D7/22 , B05D3/06
CPC分类号： B05D7/22 , B05D3/06 , B82Y30/00 , B82Y40/00 , C01B32/168 , C01B32/174
摘要： Nanotubes loaded with materials, such as active species, and methods to load materials into nanotubes are disclosed. The method includes flowing a medium containing the material to be loaded through the interior volume of the nanotube, wherein it is retained, optionally by a crosslinking or polymerization reaction. Flowing the medium occurs under different conditions and processes, including centrifuging and size exclusion methods.
摘要翻译：公开了装载材料（例如活性物质）的纳米管和将材料负载到纳米管中的方法。该方法包括使包含要加载的材料的介质流动通过纳米管的内部容积，其中其被保持，任选地通过交联或聚合反应。在不同的条件和过程下，介质的流动，包括离心和尺寸排除方法。

2. 发明授权

US07785505B2 Methods for use of fluorescent nanoparticles to determine free volume and to detect and deliver materials to repair cracks in polymers and polymer composites 有权
标题翻译：使用荧光纳米颗粒来确定自由体积并检测和输送材料以修复聚合物和聚合物复合材料中的裂纹的方法
公开(公告)号：US07785505B2
公开(公告)日：2010-08-31
申请号：US11587324
申请日：2005-04-26
申请人： Elisabeth S. Papazoglou
发明人： Elisabeth S. Papazoglou
IPC分类号： B29C45/76
CPC分类号： G01N21/64 , B82Y15/00 , B82Y30/00 , G01N33/442 , Y10S977/902 , Y10T428/2982
摘要： Methods for use of functionalized fluorescent nanoparticles in the non-destructive, direct and dynamic determination of free volume and glass transition changes and mechanical property changes of polymers and polymer composites are provided. Also provided are methods for use of functionalized fluorescent nanoparticles in tracking changes occurring in an individual component or components of a polymer composite. Methods for use of functionalized fluorescent nanoparticles in the quantitation and dynamic monitoring of crack propagation and fatigue of polymers and/or polymer composites and in the delivery of repair agents such as adhesives and/or cross-linking agents to cracks of polymers and polymer composites are provided.
摘要翻译：提供了功能化荧光纳米粒子在非破坏性，直接和动态测定聚合物和聚合物复合材料的自由体积和玻璃化转变变化和机械性能变化的方法。还提供了使用官能化荧光纳米粒子跟踪发生在聚合物复合材料的单个组分或组分中的变化的方法。使用官能化荧光纳米粒子在聚合物和/或聚合物复合材料的裂纹扩展和疲劳的定量和动态监测中以及将修复剂如粘合剂和/或交联剂递送到聚合物和聚合物复合材料的裂纹的方法是提供。

3. 发明申请

US20100152352A1 SUBSTRATES COATED WITH FLAME RETARDANT COMPOSITIONS BASED ON ORGANIC POLYMERS AND ZEOLITES 审中-公开
标题翻译：基于有机聚合物和沸石的阻燃剂组合物的基材
公开(公告)号：US20100152352A1
公开(公告)日：2010-06-17
申请号：US12635072
申请日：2009-12-10
申请人： Don Gary Barber , Elisabeth S. Papazoglou
发明人： Don Gary Barber , Elisabeth S. Papazoglou
IPC分类号： C08K5/12 , C08K3/22 , B32B37/00
CPC分类号： C08K3/2279 , B32B2307/3065 , B32B2471/02 , C08K3/016 , C08K3/22 , C08K3/34 , C08L9/06 , Y10T156/10 , C08L21/00
摘要： Substrates, which may be either flexible or rigid, are coated with a flame retardant composition containing an organic polymer, a filler and a zeolite. Good flame retardant properties are obtained even where the composition contains low levels of conventional flame retardant additives such as antimony compounds, brominated compounds and zinc compounds. The flame retardant composition may also be used to adhere different substrates together.
摘要翻译：基材可以是柔性的或刚性的，用含有机聚合物，填料和沸石的阻燃剂组合物涂覆。即使组合物含有低水平的常规阻燃添加剂如锑化合物，溴化合物和锌化合物，也可获得良好的阻燃性能。阻燃剂组合物也可用于将不同的基材粘合在一起。

4. 发明授权

US5420198A Process for the preparation of polymide blends having improved low temperature properties 失效
标题翻译：具有改进的低温性能的聚酰亚胺共混物的制备方法
公开(公告)号：US5420198A
公开(公告)日：1995-05-30
申请号：US885088
申请日：1992-05-18
申请人： Elisabeth S. Papazoglou , Jay S. Rosenthal
发明人： Elisabeth S. Papazoglou , Jay S. Rosenthal
IPC分类号： C08L23/08 , C08L23/00 , C08L25/00 , C08L25/08 , C08L35/06 , C08L51/06 , C08L53/00 , C08L53/02 , C08L73/00 , C08L77/00
CPC分类号： C08L77/00 , C08L35/06 , C08L51/06
摘要： A process for the preparation of moldable polymer blends having improved low temperature impact properties and reduced brittleness is disclosed. In one embodiment, a polyamide such as nylon-6 and an anhydride functionalized elastomer such as an EPDM rubber grafted with maleic anhydride are first melt-blended. The resulting composition is then blended with a thermoplastic copolymer of an .alpha.,.beta.-unsaturated carboxylic acid anhydride such as maleic anhydride and a monovinyl aromatic monomer such as styrene. The moldable polymer blends thus obtained are suitable for use as engineering resins.
摘要翻译：公开了一种制备具有改进的低温冲击性能和降低的脆性的可模制聚合物共混物的方法。在一个实施方案中，首先将诸如尼龙-6的聚酰胺和接枝有马来酸酐的EPDM橡胶等酸酐官能化弹性体熔融共混。然后将所得组合物与α，β-不饱和羧酸酐如马来酸酐和单乙烯基芳族单体如苯乙烯的热塑性共聚物共混。由此获得的可模制聚合物共混物适合用作工程树脂。

5. 发明授权

US08812083B2 Methods of optically monitoring wound healing 有权
标题翻译：光学监测伤口愈合的方法
公开(公告)号：US08812083B2
公开(公告)日：2014-08-19
申请号：US12937590
申请日：2009-04-21
申请人： Elisabeth S. Papazoglou , Leonid Zubkov , Michael T. Neidrauer , Linda Zhu , Kambiz Pourrezaei , Michael S. Weingarten
发明人： Elisabeth S. Papazoglou , Leonid Zubkov , Michael T. Neidrauer , Linda Zhu , Kambiz Pourrezaei , Michael S. Weingarten
IPC分类号： A61B6/00
CPC分类号： A61B5/1455 , A61B5/0059 , A61B5/0075 , A61B5/02007 , A61B5/14546 , A61B5/445 , G01N21/359 , G01N21/4738
摘要： Optical changes of tissue during wound healing measured by Near Infrared and Diffuse Reflectance Spectroscopy are shown to correlate with histologic changes. Near Infrared absorption coefficient correlated with blood vessel in-growth over time, while Diffuse Reflectance Spectroscopy (DRS) data correlated with collagen concentration. Changes of optical properties of wound tissue at greater depths are also quantified by Diffuse Photon Density Wave (DPDW) methodology at near infrared wavelengths. The diffusion equation for semi-infinite media is used to calculate the absorption and scattering coefficients based on measurements of phase and amplitude with a frequency domain or time domain device. An increase in the absorption and scattering coefficients and a decrease in blood saturation of the wounds compared to the non wounded sites was observed. The changes correlated with the healing stage of the wound. The methodologies used to collect information regarding the healing state of a wound may be used to clinically assess the efficacy of wound healing agents in a patient (e.g., a diabetic) and as a non-invasive method to detect the progress of wound healing, particularly chronic wounds due to diabetes. The methodology applies to ischemic environments, impaired healing states, and emerging subsurface tissue deterioration, such as in pressure ulcers, venous ulcers, and ubiquitous ulcers.
摘要翻译：通过近红外和漫反射光谱测量伤口愈合期间组织的光学变化显示与组织学变化相关。近红外吸收系数与血管生长随时间相关，漫反射光谱（DRS）数据与胶原浓度相关。伤口组织在较大深度的光学性质的变化也通过近红外波长的漫射光子密度波（DPDW）方法进行定量。用于半无限介质的扩散方程用于基于频域或时域装置的相位和幅度测量来计算吸收和散射系数。观察到与非伤口部位相比，吸收和散射系数的增加以及伤口的血液饱和度降低。这些变化与伤口的愈合阶段相关。用于收集关于伤口愈合状态的信息的方法可用于临床评估伤口愈合剂在患者（例如，糖尿病）中的功效以及用于检测伤口愈合进展的非侵入性方法，特别是慢性创伤由于糖尿病。该方法适用于缺血性环境，愈合状态受损，以及出现的地下组织恶化，如压力性溃疡，静脉溃疡和普遍存在的溃疡。

6. 发明申请

US20130034863A1 Apparatus and Methods for Detecting Inflammation Using Quantum Dots 审中-公开
标题翻译：使用量子点检测炎症的装置和方法
公开(公告)号：US20130034863A1
公开(公告)日：2013-02-07
申请号：US13145950
申请日：2010-01-22
申请人： Elisabeth S. Papazoglou , Sreekant Murthy , Sundar Babu Nadarajan , Sakya Sing Mohapatra
发明人： Elisabeth S. Papazoglou , Sreekant Murthy , Sundar Babu Nadarajan , Sakya Sing Mohapatra
IPC分类号： G01N21/64 , C09K11/08 , C12M1/42 , C09K11/88 , B82Y15/00
CPC分类号： G01N33/588 , B82Y15/00
摘要： Apparatus and methods for detecting an a biomarker indicative of an inflammatory condition, including a capillary tube adapted for one or more biomarkers to adhere to an interior surface thereof, a light source for energizing quantum dots conjugated with the biomarkers within the capillary tube, and a detection system for detecting and quantifying fluorescent energy emitted by the quantum dots in one or more predetermined wavelength ranges, each wavelength range being correlated to one and only one of the biomarkers. A method of stabilizing the fluorescence intensity of quantum dots is also disclosed.
摘要翻译：用于检测指示炎性病症的生物标志物的装置和方法，包括适于一种或多种生物标志物粘附到其内表面的毛细管，用于激发与毛细管内的生物标志物缀合的量子点的光源，以及用于检测和量化在一个或多个预定波长范围内由量子点发射的荧光能量的检测系统，每个波长范围与生物标记中的一个且仅一个相关联。还公开了一种稳定量子点的荧光强度的方法。

7. 发明申请

US20110124987A1 Methods for Measuring Changes in Optical Properties of Wound Tissue and Correlating Near Infrared Absorption (FNIR) and Diffuse Reflectance Spectroscopy Scattering (DRS) With Tissue Neovascularization and Collagen Concentration to Determine Whether Wound is Healing 有权
标题翻译：用于测量伤口组织和相关近红外吸收（FNIR）和弥漫性反射光谱散射（DRS）的组织新血管形成和胶原蛋白浓度以确定伤口是否愈合的光学性质变化的方法
公开(公告)号：US20110124987A1
公开(公告)日：2011-05-26
申请号：US12937590
申请日：2009-04-21
申请人： Elisabeth S. Papazoglou , Michael S. Weingarten , Leonid Zubkov , Michael T. Neidrauer , Linda Zhu , Kambiz Pourrezaei
发明人： Elisabeth S. Papazoglou , Michael S. Weingarten , Leonid Zubkov , Michael T. Neidrauer , Linda Zhu , Kambiz Pourrezaei
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/0059 , A61B5/0075 , A61B5/02007 , A61B5/14546 , A61B5/445 , G01N21/359 , G01N21/4738
摘要： Optical changes of tissue during wound healing measured by Near Infrared and Diffuse Reflectance Spectroscopy are shown to correlate with histologic changes. Near Infrared absorption coefficient correlated with blood vessel in-growth over time, while Diffuse Reflectance Spectroscopy (DRS) data correlated with collagen concentration. Changes of optical properties of wound tissue at greater depths are also quantified by Diffuse Photon Density Wave (DPDW) methodology at near infrared wavelengths. The diffusion equation for semi-infinite media is used to calculate the absorption and scattering coefficients based on measurements of phase and amplitude with a frequency domain or time domain device. An increase in the absorption and scattering coefficients and a decrease in blood saturation of the wounds compared to the non wounded sites was observed. The changes correlated with the healing stage of the wound. The methodologies used to collect information regarding the healing state of a wound may be used to clinically assess the efficacy of wound healing agents in a patient (e.g., a diabetic) and as a non-invasive method
摘要翻译：通过近红外和漫反射光谱测量伤口愈合期间组织的光学变化显示与组织学变化相关。近红外吸收系数与血管生长随时间相关，漫反射光谱（DRS）数据与胶原浓度相关。伤口组织在较大深度的光学性质的变化也通过近红外波长的漫射光子密度波（DPDW）方法进行定量。用于半无限介质的扩散方程用于基于频域或时域装置的相位和幅度测量来计算吸收和散射系数。观察到与非伤口部位相比，吸收和散射系数的增加以及伤口的血液饱和度降低。这些变化与伤口的愈合阶段相关。用于收集关于伤口愈合状态的信息的方法可以用于临床评估伤口愈合剂在患者（例如，糖尿病）中的功效和作为非侵入性方法

8. 发明申请

US20090137174A1 FLAME-RETARDANT POLYMERIC COMPOSITIONS 审中-公开
标题翻译：阻燃聚合物组合物
公开(公告)号：US20090137174A1
公开(公告)日：2009-05-28
申请号：US12266995
申请日：2008-11-07
申请人： Don Gary Barber , Elisabeth S. Papazoglou
发明人： Don Gary Barber , Elisabeth S. Papazoglou
IPC分类号： B32B27/04 , C08K3/34 , C08K5/06 , C08K5/3417 , C08K5/51
CPC分类号： C08K3/34 , C08K5/0066 , C08K5/02 , C08K5/06 , C08K5/3435 , Y10T442/2713 , C08L23/02
摘要： A flame-retarded polymeric composition is provided which contains a) a polyolefin, b) a mixture of a halogenated flame-retardant and zeolite, and optionally c) a synergist. Also provided is a flame and smoke-retarded polymeric composition containing a polyolefin and a mixture of a hydrated metal oxide and zeolite.
摘要翻译：提供了一种阻燃聚合物组合物，其包含a）聚烯烃，b）卤化阻燃剂和沸石的混合物，以及任选的c）增效剂。还提供了含有聚烯烃和水合金属氧化物和沸石的混合物的火焰和阻燃聚合物组合物。

9. 发明授权

US5216075A Impact resistant polyblends of polyamides, acid copolymers and anhydride functionalized elastomers 失效
标题翻译：聚酰胺，酸共聚物和非离子官能化弹性体的抗冲击聚苯乙烯
公开(公告)号：US5216075A
公开(公告)日：1993-06-01
申请号：US518898
申请日：1990-05-04
申请人： Elisabeth S. Papazoglou
发明人： Elisabeth S. Papazoglou
IPC分类号： C08L23/08 , C08L25/00 , C08L25/08 , C08L33/02 , C08L51/04 , C08L53/00 , C08L53/02 , C08L73/00 , C08L77/00
CPC分类号： C08L51/04 , C08L33/02 , C08L77/00
摘要： Moldable multi-phase polyblends having excellent impact properties are disclosed which comprise blends of a polyamide, a thermoplastic copolymer of an .alpha.,.beta.-unsaturated carboxylic acid and a monovinyl aromatic monomer, and an anhydride-functionalized elastomer. The functionalized elastomers are low in unsaturation, providing polyblends having good oxidative stability, and are .alpha.,.beta.-carboxylic acid anhydride adducts of EPDM-type rubbers, hydrogenated block or random copolymers of monovinyl aromatic monomers and conjugated dienes, or hydrogenated polymers of conjugated dienes. Optimum impact properties are achieved by combining the components of the polyblends using particular melt-blending procedures.

10. 发明申请

US20110208063A1 NON-CONTACT FREQUENCY DOMAIN NEAR INFRARED ABSORPTION (fNIR) DEVICE FOR ASSESSING TISSUE DAMAGE 审中-公开
标题翻译：非接触式频率域近红外吸收（fNIR）用于评估组织损伤的装置
公开(公告)号：US20110208063A1
公开(公告)日：2011-08-25
申请号：US13125116
申请日：2009-11-06
申请人： Elisabeth S. Papazoglou , Leonid Zubkov
发明人： Elisabeth S. Papazoglou , Leonid Zubkov
IPC分类号： A61B6/00
CPC分类号： A61B5/0059 , A61B5/0077 , A61B5/445 , A61B5/7228 , A61B2560/0223 , A61B2562/0242
摘要： A device for measuring the progress of healing of a wound over time includes at least one diode laser source that provides respective input wavelengths into at least one source fiber, a first optical switch that sequentially switches wavelengths among the respective input wavelengths into the at least one source fiber, a probe that does not touch the wound dunng use, the probe including the at least one source fiber and at least two detectors spaced thereon, an optical system that provides source light from the at least one source fiber to the wound and that detects light scattered by the wound surface and provides the scattered light to the detectors, and a processing unit responsive to outputs of the detectors for providing at least four independent measurements for calculation of an absorption coefficient/Ia and a scattering coefficient/I's of the light by the wound
摘要翻译：用于测量随着时间的伤口愈合进展的装置包括至少一个二极管激光源，其将相应的输入波长提供给至少一个源光纤;第一光开关，其顺序地将各个输入波长中的波长切换到至少一个所述探针包括所述至少一个源光纤和至少两个间隔开的检测器，所述探针包括至少一个源光纤和至少两个间隔开的检测器;光学系统，其将来自所述至少一个源光纤的光源提供给所述伤口; 检测由伤口表面散射的光并将散射光提供给检测器，以及响应于检测器的输出的处理单元，用于提供用于计算光的吸收系数/ Ia和散射系数/ I的至少四个独立测量值受伤

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