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1. 发明授权

US08962580B2 Chemical modifications of monomers and oligonucleotides with cycloaddition 有权
标题翻译：具有环加成的单体和寡核苷酸的化学修饰
公开(公告)号：US08962580B2
公开(公告)日：2015-02-24
申请号：US13120389
申请日：2009-09-23
申请人： Muthiah Manoharan , Kallanthottathil G. Rajeev , Takeshi Yamada , David Butler , Narayanannair K. Jayaprakash , Muthusamy Jayaraman , Shigeo Matsuda , Rajendra K. Pandey , Chang Geng Peng
发明人： Muthiah Manoharan , Kallanthottathil G. Rajeev , Takeshi Yamada , David Butler , Narayanannair K. Jayaprakash , Muthusamy Jayaraman , Shigeo Matsuda , Rajendra K. Pandey , Chang Geng Peng
IPC分类号： A61K48/00 , H04L29/06 , C07H21/00 , H04L29/08
CPC分类号： C12N15/113 , A61K31/713 , A61K47/544 , A61K47/64 , C07H21/00 , C12N2310/14 , C12N2310/141 , C12N2310/3513 , C12N2310/3515 , H04L65/602 , H04L67/36 , Y02A50/465
摘要： The invention features compounds of formula I or II: In one embodiment, the invention relates compounds and processes for conjugating ligand to oligonucleotide. The invention further relates to methods for treating various disorders and diseases such as viral infections, bacterial infections, parasitic infections, cancers, allergies, autoimmune diseases, immunodeficiencies and immunosuppression.
摘要翻译：本发明的特征在于式I或II化合物：在一个实施方案中，本发明涉及将配体与寡核苷酸缀合的化合物和方法。本发明还涉及治疗各种病症和疾病如病毒感染，细菌感染，寄生虫感染，癌症，过敏症，自身免疫疾病，免疫缺陷和免疫抑制的方法。

2. 发明申请

US20120035115A1 CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION 有权
标题翻译：单体和二聚体的化学修饰与循环
公开(公告)号：US20120035115A1
公开(公告)日：2012-02-09
申请号：US13120389
申请日：2009-09-23
申请人： Muthiah Manoharan , Kallanthottathil G. Rajeev , Takeshi Yamada , David Butler , K. Narayanannair Jayaprakash , Muthusamy Jayraman , Shigeo Matsuda , Rajendra K. Pandey , Chang Geng Peng
发明人： Muthiah Manoharan , Kallanthottathil G. Rajeev , Takeshi Yamada , David Butler , K. Narayanannair Jayaprakash , Muthusamy Jayraman , Shigeo Matsuda , Rajendra K. Pandey , Chang Geng Peng
IPC分类号： A61K38/14 , C07H19/10 , C07F9/6561 , C07H21/02 , A61K31/7072 , A61K31/675 , C07H1/00 , A61P31/12 , A61P31/04 , A61P33/00 , A61P35/00 , A61P37/08 , A61P37/06 , A61P37/04 , C07K9/00 , A61K31/7088
CPC分类号： C12N15/113 , A61K31/713 , A61K47/544 , A61K47/64 , C07H21/00 , C12N2310/14 , C12N2310/141 , C12N2310/3513 , C12N2310/3515 , H04L65/602 , H04L67/36 , Y02A50/465
摘要： The invention features compounds of formula I or II: In one embodiment, the invention relates compounds and processes for conjugating ligand to oligonucleotide. The invention further relates to methods for treating various disorders and diseases such as viral infections, bacterial infections, parasitic infections, cancers, allergies, autoimmune diseases, immunodeficiencies and immunosuppression.
摘要翻译：本发明的特征在于式I或II化合物：在一个实施方案中，本发明涉及将配体与寡核苷酸缀合的化合物和方法。本发明还涉及治疗各种病症和疾病如病毒感染，细菌感染，寄生虫感染，癌症，过敏症，自身免疫疾病，免疫缺陷和免疫抑制的方法。

3. 发明授权

US08981080B2 Silane-modified cationized polymeric compound and process for production thereof 有权
标题翻译：硅烷改性阳离子化聚合物及其制备方法
公开(公告)号：US08981080B2
公开(公告)日：2015-03-17
申请号：US13320787
申请日：2010-05-18
申请人： Takeshi Yamada , Youichirou Kohno , Yoko Osako , Yoshifumi Yamagata
发明人： Takeshi Yamada , Youichirou Kohno , Yoko Osako , Yoshifumi Yamagata
IPC分类号： C08B15/06 , D21C3/00 , D21C3/22 , C08B15/00
CPC分类号： C08B15/06
摘要： A process for producing a silane-modified cationized polymeric compound, the process including the steps of: (1) cationizing a water-soluble polymeric compound in a mixed solvent of a water-miscible organic solvent and water in the presence of an alkali to produce a slurry containing a cationized polymeric compound, (2) adding an aminosilane compound to the slurry or a cake produced therefrom, thereby treating the cationized polymeric compound with the aminosilane compound, (3) optionally adding an acid to the slurry obtained in step (1) or a product obtained in step (2), and (4) drying a product obtained in step (2) or a product obtained by performing step (3) after step (2), wherein the drying step (4) includes a primary drying treatment step of performing drying at a temperature of 50 to 140° C. under a degree of vacuum of 4.0 to 53.3 kPa, and a secondary drying treatment step of drying the product obtained following the primary drying treatment at a temperature of 90 to 155° C. The process enables a silane-modified cationized polymeric compound having excellent water dispersibility to be produced with good efficiency.
摘要翻译：一种制备硅烷改性阳离子化聚合物的方法，该方法包括以下步骤：（1）在碱存在下，将水溶性有机溶剂与水的混合溶剂中的水溶性高分子化合物阳离子化以产生含有阳离子化聚合物的浆料，（2）向浆料中添加氨基硅烷化合物或由其制备的饼，由此用氨基硅烷化合物处理阳离子化聚合物，（3）任选地向步骤（1）中获得的浆料中加入酸）或步骤（2）中获得的产物，和（4）在步骤（2）之后干燥步骤（2）中获得的产物或通过步骤（3）获得的产物，其中干燥步骤（4）干燥处理步骤，在真空度为4.0〜53.3kPa的条件下，在50〜140℃的温度下进行干燥，二次干燥处理工序在90〜155℃的温度下进行一次干燥处理后得到的产物 ℃ 该方法能够以高效率生产具有优异的水分散性的硅烷改性阳离子化聚合物。

4. 发明授权

US08722516B2 Laser processing method and method for manufacturing light-emitting device 有权
标题翻译：激光加工方法及其制造方法
公开(公告)号：US08722516B2
公开(公告)日：2014-05-13
申请号：US13233662
申请日：2011-09-15
申请人： Takeshi Yamada , Masaharu Hoshikawa , Yasunaga Nara
发明人： Takeshi Yamada , Masaharu Hoshikawa , Yasunaga Nara
IPC分类号： H01L21/00
CPC分类号： H01L33/0095 , B23K26/032 , B23K26/0622 , B23K26/0853 , B23K26/40 , B23K26/53 , B23K2101/40 , B23K2103/172 , B23K2103/50 , B28D5/0011
摘要： A plurality of modified parts are formed at a first formation pitch for a line arranged along the M-plane of a single-crystal sapphire substrate to construct a modified region and cause a fracture occurring from the modified region to reach a principal surface of the single-crystal sapphire substrate. A plurality of modified parts are formed at a second formation pitch narrower than the first formation pitch for a line arranged along the A-plane of the single-crystal sapphire substrate to construct a modified region and cause a fracture occurring from the modified region to reach the principal surface of the single-crystal sapphire substrate. Along the lines, a knife edge is pressed against a wafer from the side of the single-crystal sapphire substrate opposite from the principal surface of the single-crystal sapphire substrate where the fractures have reached, to cut the wafer along the lines.
摘要翻译：沿着单晶蓝宝石衬底的M面布置的线以第一形成间距形成多个改性部分，以构成改质区域，并使得从改质区域发生的断裂达到单面蓝宝石衬底的主面晶体蓝宝石衬底。多个改性部分以比单晶蓝宝石衬底的A平面布置的线的第一形成间距窄的第二形成间距形成，以构成改质区域，并使得从改质区域发生的断裂达到单晶蓝宝石衬底的主表面。沿着线条，将刀刃从单晶蓝宝石衬底的与单晶蓝宝石衬底的主要表面相对的侧面压到晶片上，在该晶圆的主表面上已达到裂缝，沿着线切割晶片。

5. 发明申请

US20130164480A1 ELASTIC LAMINATE SHEET 审中-公开
标题翻译：弹性层压片
公开(公告)号：US20130164480A1
公开(公告)日：2013-06-27
申请号：US13819984
申请日：2011-08-22
申请人： Hiroshi Sakurai , Takeshi Yamada , Hirofumi Hosokawa
发明人： Hiroshi Sakurai , Takeshi Yamada , Hirofumi Hosokawa
IPC分类号： B32B3/16
CPC分类号： B32B37/08 , B32B5/14 , B32B27/12 , B32B37/153 , B32B2307/51 , B32B2309/02 , B32B2309/14 , B32B2555/02 , Y10T428/187
摘要： An elastic laminate sheet comprising a laminate comprising an elastomer layer and a nonwoven fabric provided on at least one surface of the elastomer layer, wherein low elastic laminate part and high elastic laminate part are alternatingly provided in one direction to form the laminate, and the low elastic laminate part and the high elastic laminate part both have a first bonding region where the elastomer layer and the nonwoven fabric are bonded and a second bonding region where the elastomer and the nonwoven fabric are bonded more weakly than at the first bonding region, and a total surface area of the first bonding region in the low elastic laminate part is larger than a total surface area of the first bonding region in the high elastic laminate part, and a ratio of an elastic modulus of the low elastic laminate part to an elastic modulus of the high elastic laminate part is more than 1 and not more than 7.5. The elastic laminate sheet does not easily break even when repeatedly stretched and demonstrates sufficient retention capacity for practical use even when attached to a main body part of a hygienic article or the like.
摘要翻译：一种弹性层压片，其包括弹性体层和设置在所述弹性体层的至少一个表面上的无纺布的层压体，其中低弹性层压体部分和高弹性层压体部分沿一个方向交替设置以形成所述层压体，并且所述低弹性层压体部分和高弹性层压体部分均具有接合弹性体层和无纺布的第一接合区域和弹性体和非织造织物比第一接合区域更弱的第二接合区域，以及低弹性层叠体中的第一接合区域的总表面积比高弹性层叠体的第一接合区域的总面积大，低弹性层叠体的弹性模量与弹性模量的高弹性层压体部分大于1且不大于7.5。弹性层压片即使在重复拉伸时也不容易断裂，即使在附着于卫生用品等的主体部分时也能够实际使用。

6. 发明申请

US20130133624A1 TWO-CYCLE ENGINE 有权
标题翻译：双循环发动机
公开(公告)号：US20130133624A1
公开(公告)日：2013-05-30
申请号：US13813434
申请日：2011-08-04
申请人： Takayuki Hirose , Takeshi Yamada , Yasunori Ashikaga , Takayuki Yamada , Takahiro Kuge , Takahiro Takimoto , Mamoru Nomura
发明人： Takayuki Hirose , Takeshi Yamada , Yasunori Ashikaga , Takayuki Yamada , Takahiro Kuge , Takahiro Takimoto , Mamoru Nomura
IPC分类号： F02M51/06
CPC分类号： F02M51/06 , F02B25/04 , F02D19/061 , F02D19/0689 , F02D19/0692 , F02D19/10 , F02M21/0212 , F02M21/0275 , Y02T10/32 , Y02T10/36
摘要： Disclosed herein is a two-cycle engine that includes an exhaust port which is opened and closed at one end portion in a longitudinal direction of a cylinder; a scavenging port which is opened and closed at the other end portion in the longitudinal direction of the cylinder; and a fuel injection port which injects a fuel into the cylinder provided between the exhaust port and the scavenging port, wherein the fuel begins to be injected in a state in which at least any one of the exhaust port and the scavenging port is opened.
摘要翻译：这里公开了一种双冲程发动机，其包括在气缸的纵向方向上的一个端部处打开和关闭的排气口; 在气缸的长度方向的另一端部开闭的清扫口; 以及燃料喷射口，其将燃料喷射到设置在排气口和扫气口之间的气缸中，其中燃料开始以排气口和扫气口中的至少任一个打开的状态喷射。

7. 发明申请

US20120238701A1 AQUEOUS POLYURETHANE RESIN DISPERSION, PROCESS FOR PREPARING THE SAME AND USE THEREOF 审中-公开
标题翻译：水性聚氨酯树脂分散体，其制备方法和用途
公开(公告)号：US20120238701A1
公开(公告)日：2012-09-20
申请号：US13508934
申请日：2010-11-08
申请人： Takeshi Yamada , Masahiro Naiki
发明人： Takeshi Yamada , Masahiro Naiki
IPC分类号： C09D175/06
CPC分类号： C08G18/0823 , C08G18/12 , C08G18/44 , C09D5/02 , C09D175/04 , D06N3/14 , D06N3/146 , D06N2205/023 , D06N2209/14 , D06N2209/1642 , D06N2211/28
摘要： An object is to obtain an aqueous polyurethane resin dispersion which provides a coating film having high hardness, oleic acid resistance and solvent resistance.The aqueous polyurethane resin dispersion comprises a polyurethane resin obtained by reacting (a) a polyol compound, (b) a polyisocyanate compound, (c) an acidic group-containing polyol compound and (d) a chain-elongating agent being dispersed in an aqueous medium, wherein (a) the polyol compound comprises a polycarbonate polyol compound represented by the formula (1), a hydroxyl equivalent of (a) the polyol compound and (c) the acidic group-containing polyol compound is 180 to 400, and a total acid value of (a) the polyol compound, (b) the polyisocyanate compound and (c) the acidic group-containing polyol compound is 22 to 40 mg KOH/g.
摘要翻译：本发明的目的是获得提供具有高硬度，耐油酸性和耐溶剂性的涂膜的水性聚氨酯树脂分散体。水性聚氨酯树脂分散体包含通过使（a）多元醇化合物，（b）多异氰酸酯化合物，（c）含酸性基团的多元醇化合物和（d）分散在水性聚合物中的增链剂其中（a）多元醇化合物包含由式（1）表示的聚碳酸酯多元醇化合物，（a）多元醇化合物的羟基当量和（c）含酸性基团的多元醇化合物的摩尔比为180-400，和（a）多元醇化合物，（b）多异氰酸酯化合物和（c）含酸性基团的多元醇化合物的总酸值为22〜40mgKOH / g。

8. 发明授权

US07917271B2 Vehicle and traveling state determination method of vehicle 有权
标题翻译：车辆行驶状态判定方法
公开(公告)号：US07917271B2
公开(公告)日：2011-03-29
申请号：US11892252
申请日：2007-08-21
申请人： Takeshi Yamada
发明人： Takeshi Yamada
IPC分类号： G06F7/70 , G06G7/00 , G06G7/76 , B60Q1/00
CPC分类号： G01M17/007
摘要： When an accelerator opening Acc is smaller than a flat road threshold Aref1, an ECO indicator is illuminated, and when the accelerator opening Acc is equal to or larger than a climbing road threshold Aref2 larger than the flat road threshold Aref1, the ECO indicator is extinguished (S120 and S220), when the accelerator opening Acc is equal to or larger than the flat road threshold Aref1 and smaller than the climbing road threshold Aref2, the previous state of the ECO indicator is maintained until climbing road determination performed based on a vehicle speed V is finished, and when the climbing road determination is finished, the ECO indicator is illuminated or extinguished based on the result of the determination.
摘要翻译：当加速器开度Acc小于平均道路阈值Aref1时，ECO指示灯被点亮，并且当加速器开度Acc等于或大于比平均道路阈值Aref1大的上升道路阈值Aref2时，ECO指示符熄灭（S120和S220），当加速器开度Acc等于或大于平均道路阈值Aref1并且小于爬升道路阈值Aref2时，保持ECO指示器的先前状态，直到基于车速进行上升道路确定 V结束，当攀登道路确定结束时，根据确定结果，ECO指示灯被点亮或熄灭。

9. 发明申请

US20100259677A1 IMAGE DISPLAY SYSTEM 审中-公开
标题翻译：图像显示系统
公开(公告)号：US20100259677A1
公开(公告)日：2010-10-14
申请号：US12688627
申请日：2010-01-15
申请人： Kazuaki MATOBA , Takeshi Yamada , Yasutaka Kuroda , Susumu Nakagakiuchi
发明人： Kazuaki MATOBA , Takeshi Yamada , Yasutaka Kuroda , Susumu Nakagakiuchi
IPC分类号： H04N7/00
CPC分类号： H04N5/445 , H04N21/235 , H04N21/4122 , H04N21/431 , H04N21/435 , H04N21/488
摘要： An image display system according to the present invention includes a host terminal which is a terminal transmitting character code information, and an image display device connected to the host terminal through a network and displaying an image. The image display device includes: an input source selecting means as a first input means to which video signals are inputted, a network I/F means as a first network interface means for receiving the character code information transmitted from the host terminal, a character image generating means for generating a character image from the character code information in the network. I/F means, an image synthesis means synthesizing the video signals in the input source selecting means and the character image in the character image generating means, and an image display means displaying the image synthesized in the image synthesis means.
摘要翻译：根据本发明的图像显示系统包括作为终端发送字符代码信息的主机终端和通过网络连接到主机终端并显示图像的图像显示装置。图像显示装置包括：作为输入视频信号的第一输入装置的输入源选择装置，作为用于接收从主机终端发送的字符代码信息的第一网络接口装置的网络I / F装置，用于从网络中的字符码信息生成字符图像的生成装置。 I / F装置，合成在输入源选择装置中的视频信号和字符图像产生装置中的字符图像的图像合成装置，以及显示在图像合成装置中合成的图像的图像显示装置。

10. 发明授权

US07455008B2 Swash plate compressor 失效
标题翻译：斜盘式压缩机
公开(公告)号：US07455008B2
公开(公告)日：2008-11-25
申请号：US10570470
申请日：2004-08-06
申请人： Hajime Kurita , Takayuki Imai , Masakazu Murase , Masaki Ota , Tetsuhiko Fukanuma , Takeshi Yamada
发明人： Hajime Kurita , Takayuki Imai , Masakazu Murase , Masaki Ota , Tetsuhiko Fukanuma , Takeshi Yamada
IPC分类号： F01B3/02
CPC分类号： F04B27/1063 , F04B27/1054
摘要： A first swash plate 18 is coupled to a drive shaft 16 to be rotatable integrally with the drive shaft 16. Single head pistons 23 are coupled to the first swash plate 18 via shoes 25A, 25B. Rotation of the drive shaft 16 rotates the first swash plate 18, which causes the pistons 23 to reciprocate and compress refrigerant gas. The first swash plate 18 supports an annular second swash plate 51 to be rotatable relative to the first swash plate 18 via a ball bearing 52. The second swash plate 51 is arranged between the first swash plate 18and the shoes 25B that receive a compressive load to be slidable with respect to the first swash plate 18 and the shoes 25B. Therefore, the first swash plate reliably slides with respect to the second swash plate.
摘要翻译：第一斜盘18联接到驱动轴16以与驱动轴16一体旋转。单头活塞23经由靴子25A，25B联接到第一斜盘18.驱动轴16的旋转使第一斜盘18旋转，这使得活塞23往复运动并压缩制冷剂气体。第一斜盘18支撑环形的第二斜盘51，经由球轴承52相对于第一斜盘18可转动。第二斜盘51布置在第一旋转斜盘18和滚珠25B之间，该第一旋转斜盘18和第二斜板18B相对于第一斜盘18和滑靴25B相对于第一斜盘18可滑动。因此，第一斜盘可靠地相对于到第二个斜盘。

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