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1. 发明申请

US20100075343A1 NOVEL PEPTIDES 审中-公开
标题翻译：新款PEPTIDES
公开(公告)号：US20100075343A1
公开(公告)日：2010-03-25
申请号：US12524036
申请日：2007-11-29
申请人： Motoo Yamasaki , Noriyuki Takahashi , Naoto Minamino , Kazuki Sasaki , Toshifumi Takao , Yoshinori Satomi , Yoichi Ueta
发明人： Motoo Yamasaki , Noriyuki Takahashi , Naoto Minamino , Kazuki Sasaki , Toshifumi Takao , Yoshinori Satomi , Yoichi Ueta
IPC分类号： G01N33/53 , C07K14/00 , C07K7/06 , C07K7/08 , C07H21/00 , C12N15/63 , C12N5/00 , C12P21/00 , C07K16/00 , C12Q1/02
CPC分类号： C07K16/22 , A61K38/00 , C07K14/47 , G01N33/5008
摘要： The present invention provides novel peptides with energy-modulating activity or circulatory function-modulating activity. The peptides of the present invention have energy-modulating activity or circulatory function-modulating activity and thus are useful for treating food consumption disorders and diseases of the circulatory system.
摘要翻译：本发明提供具有能量调节活性或循环功能调节活性的新型肽。本发明的肽具有能量调节活性或循环功能调节活性，因此可用于治疗食物消耗障碍和循环系统的疾病。

2. 发明申请

US20100248255A1 NOVEL PEPTIDES 审中-公开
标题翻译：新款PEPTIDES
公开(公告)号：US20100248255A1
公开(公告)日：2010-09-30
申请号：US11997144
申请日：2006-07-28
申请人： Motoo Yamasaki , Noriyuki Takahashi , Naoto Minamino , Kazuki Sasaki , Toshifumi Takao , Yoshinori Satomi
发明人： Motoo Yamasaki , Noriyuki Takahashi , Naoto Minamino , Kazuki Sasaki , Toshifumi Takao , Yoshinori Satomi
IPC分类号： G01N33/53 , C07K14/00 , C07K7/08 , C07H21/04 , C07K16/00 , C12N15/63 , C12N5/00 , C12P21/06 , C12Q1/02
CPC分类号： C07K14/475 , A61K38/00 , C07K16/22 , G01N2800/325
摘要： The present invention provides novel peptides with circulation-modulating activity. These peptides are useful as circulation-modulating agents and vasopressors because of their circulation-modulating activity, and can be used for treating diseases of the circulatory system such as myocardial infarction, ischemic heart disease, cerebral infarction, or the like.
摘要翻译：本发明提供具有循环调节活性的新型肽。这些肽由于其循环调节活性而可用作循环调节剂和血管加压剂，并且可用于治疗循环系统的疾病，例如心肌梗塞，缺血性心脏病，脑梗死等。

3. 发明申请

US20100040621A1 Novel polpeptide and use thereof 审中-公开
标题翻译：新型多肽及其用途
公开(公告)号：US20100040621A1
公开(公告)日：2010-02-18
申请号：US11919140
申请日：2006-04-26
申请人： Masamitsu Nakazato , Toshifumi Takao
发明人： Masamitsu Nakazato , Toshifumi Takao
IPC分类号： C07K14/00 , C12N15/11 , C12N15/63 , C12N5/00 , C12P21/02 , C07K16/00 , G01N33/566 , C07H21/04 , A01K67/027 , A61K38/16 , A61K31/7105 , A61P3/10 , A61P3/00 , A61K39/395
CPC分类号： C07K16/26 , A61K38/00 , C07K14/575 , G01N33/74
摘要： The present invention provides various useful polypeptides and so on. In particular, a polypeptide comprising the amino acid sequence represented by SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8 or SEQ ID NO: 9, a compound or its salt that promotes the activity of said polypeptide, etc. can be utilized as a preventive/therapeutic agent for, e.g., renal edema, dysuria, hyponatremia, syndrome of inappropriate secretion of antidiuretic hormone, hypertension or the like. Furthermore, a compound or its salt that inhibits the activity of the polypeptide is useful as a preventive/therapeutic agent for, e.g., urine storage disorders, polyuria, diabetes insipidus, hypernatremia, metabolic alkalosis, hypokalemia, Cushing syndrome or the like. Moreover, the polypeptide comprising the amino acid sequence represented by SEQ ID NO: 7, SEQ ID NO: 8 or SEQ ID NO: 9 can be utilized as a preventive/therapeutic agent for anorexia, etc., an eating (appetite) stimulant, or the like.
摘要翻译：本发明提供各种有用的多肽等等。特别地，包含由SEQ ID NO：4，SEQ ID NO：5，SEQ ID NO：6，SEQ ID NO：7，SEQ ID NO：8或SEQ ID NO：9表示的氨基酸序列的多肽，化合物或其促进所述多肽的活性的盐等可以用作例如肾水肿，排尿困难，低钠血症，抗利尿激素不适的分泌综合征，高血压等的预防/治疗剂。此外，抑制多肽的活性的化合物或其盐可用作例如尿储存障碍，多尿，尿崩症，高钠血症，代谢性碱中毒，低钾血症，库兴综合征等的预防/治疗剂。此外，包含SEQ ID NO：7，SEQ ID NO：8或SEQ ID NO：9表示的氨基酸序列的多肽可以用作厌食症等的预防/治疗剂，食欲（食欲）兴奋剂，或类似物。

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