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1. 发明授权

US09439725B2 Ablation catheter with balloon 有权
标题翻译：消融导管与气球
公开(公告)号：US09439725B2
公开(公告)日：2016-09-13
申请号：US14123595
申请日：2012-06-08
申请人： Hiroyuki Harada , Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
发明人： Hiroyuki Harada , Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
IPC分类号： A61B18/12 , A61B18/14 , A61B18/00
CPC分类号： A61B18/1492 , A61B2018/0022 , A61B2018/00357 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00821
摘要： A balloon ablation catheter achieves reduction in diameter of the balloon upon balloon contraction and increased reliability of the thermocouple temperature sensor, which balloon ablation catheter is less likely to be influenced by the heating liquid discharged into the balloon and able to control the balloon surface temperature with high accuracy. The balloon ablation catheter includes a shaft wherein a lumen is formed; a balloon wherein the lumen communicates with the inside thereof; and a high-frequency-current-applying electrode formed by coiling a high-frequency-power-supplying lead wire around the shaft while sandwiching a temperature sensor lead wire between the high-frequency-power-supplying lead wire and the shaft such that the temperature sensor lead wire is fixed along the longitudinal direction of the shaft; wherein a thermocouple thermosensor is formed at the point where the high-frequency-power-supplying lead wire and the temperature sensor lead wire constituting the high-frequency-current-applying electrode contact with each other for the first time as seen from the posterior end side in the longitudinal direction.
摘要翻译：球囊消融导管在球囊收缩时实现球囊直径的减小，并且增加了热电偶温度传感器的可靠性，气球消融导管不太可能受到排放到球囊中的加热液体的影响，并且能够用高准确率。气囊消融导管包括其中形成内腔的轴; 气囊，其中内腔与其内部连通; 以及高频电流施加电极，其通过在高频供电引线和轴之间夹着温度传感器引线而将围绕轴的高频供电引线卷绕而形成，使得温度传感器引线沿轴的长度方向固定; 其特征在于，在构成所述高频电流施加电极的所述高频供电引线和所述温度传感器引线从所述后端观察时第一次形成热电偶热敏电阻侧纵向。

2. 发明授权

US08894588B2 Guidewire and ablation catheter system with balloon 有权
标题翻译：导丝和消融导管系统与气球
公开(公告)号：US08894588B2
公开(公告)日：2014-11-25
申请号：US13319701
申请日：2010-05-18
申请人： Akinori Matsukuma , Motoki Takaoka , Takahiro Yagi
发明人： Akinori Matsukuma , Motoki Takaoka , Takahiro Yagi
IPC分类号： A61B5/00 , A61M25/00 , A61B18/14 , A61M25/09 , A61B17/22 , A61B18/00
CPC分类号： A61M25/09 , A61B18/1492 , A61B2017/22038 , A61B2018/00285 , A61M2025/09133 , A61M2025/09183
摘要： Provided is a guide wire, wherein a deformed portion formed by bending and/or curving the guide wire is located in the region of 20-100 mm from the tip in the longitudinal direction of the guide wire, and in the deformed portion, the shortest distance between the central axis in the longitudinal direction of the guide wire and a point that is the farthest in the direction perpendicular to the central axis is longer than or equal to the minimum inside diameter of a lumen of a catheter shaft of an ablation catheter with a balloon used in combination with the guide wire, and shorter than or equal to 40 mm.
摘要翻译：本发明提供一种引导线，其中通过弯曲和/或弯曲导丝而形成的变形部分位于与引导件的纵向方向上的尖端相距20-100mm的区域中，并且在变形部分中，最短引导线的纵向方向上的中心轴与垂直于中心轴的方向最远的点之间的距离大于或等于消融导管的导管轴的内腔的最小内径，与导丝组合使用的气囊，并且小于或等于40mm。

3. 发明授权

US09393065B2 Stirring method and ablation catheter system with balloon 有权
标题翻译：用气球搅拌法和消融导管系统
公开(公告)号：US09393065B2
公开(公告)日：2016-07-19
申请号：US13260793
申请日：2010-03-30
申请人： Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
发明人： Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
IPC分类号： A61B18/04 , A61B18/00
CPC分类号： A61B18/04 , A61B2018/00577 , A61B2018/046
摘要： Provided is an ablation catheter system with a balloon which can improve the effect of therapy by ablation by eliminating variation in the surface temperature of a balloon in the ablation catheter with a balloon which cauterizes the tissue. An ablation catheter system with a balloon comprising a catheter shaft, a balloon fixed to the catheter shaft, a lumen which penetrates the catheter shaft in the direction of the long axis and communicates with the interior of the balloon, a heating electrode arranged in the balloon, a heating device which applies electrical energy to the heating electrode, and a vibration imparting device which imparts a vibration to the heating liquid by periodically repeating suction and ejection of the heating liquid from the lumen. Also provided is a stirring method for stirring the heating liquid by vibration wherein the vibration is imparted in such a manner that the value obtained by dividing the volume of the heating liquid being ejected toward the balloon by single ejection by the expansion volume of the balloon and then multiplying the quotient by 100 becomes 2-9.
摘要翻译：提供了一种具有气囊的消融导管系统，其可以通过消除烧蚀导管中的气球的表面温度的变化来改善烧蚀治疗的效果，其中烧灼组织的球囊。一种具有球囊的消融导管系统，包括导管轴，固定到导管轴的球囊，沿长轴方向穿透导管轴并与球囊内部连通的内腔，布置在球囊内的加热电极，向加热电极施加电能的加热装置，以及通过周期性地重复地从内腔抽吸和喷射加热液体而向加热液体施加振动的振动赋予装置。还提供了一种用于通过振动来搅拌加热液体的搅拌方法，其中施加振动，使得通过将通过气球的膨胀体积单次喷射朝向气球喷射的加热液体的体积所得到的值和然后将商乘以100变为2-9。

4. 发明授权

US09351784B2 Shaft for ablation catheter with balloon 有权
标题翻译：轴用消融导管与气球
公开(公告)号：US09351784B2
公开(公告)日：2016-05-31
申请号：US13260807
申请日：2010-03-30
申请人： Takahiro Yagi , Motoki Takaoka , Akinori Matsukuma
发明人： Takahiro Yagi , Motoki Takaoka , Akinori Matsukuma
IPC分类号： A61B18/04 , A61B18/14 , A61B18/00
CPC分类号： A61B18/04 , A61B18/1492 , A61B2018/00166 , A61B2018/0022 , A61B2018/00404 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61B2018/046 , A61B2018/1472
摘要： The stirring efficiency of a heating liquid which is supplied to the balloon of a balloon-equipped ablation catheter is increased to quickly uniformize the surface temperature of the balloon, and air is prevented from remaining in the balloon-equipped ablation catheter to enhance the safety of treatment which uses the balloon-equipped ablation catheter. A shaft for a balloon-equipped ablation catheter, consisting of a single pipe, wherein the shaft has two lumens which communicate from the distal end to the proximal end of the shaft, a first lumen being a guide wire passage lumen which is provided in order to allow a guide wire to pass therethrough, the second lumen being a liquid supply lumen which is provided in order to supply liquid to the inside of the balloon of the balloon-equipped ablation catheter.
摘要翻译：提供给装有球囊的消融导管的球囊的加热液体的搅拌效率增加，以使球囊的表面温度快速均匀化，并且防止空气残留在装有球囊的消融导管中以提高安全性使用装有气球的消融导管的治疗。一种用于球囊装备的消融导管的轴，由单个管组成，其中所述轴具有从所述轴的远端连接到所述近端的两个腔，第一腔是依次设置的导丝通道腔，以允许导丝通过其中，第二内腔是液体供应腔，其被设置用于将液体供应到装有球囊的消融导管的球囊的内部。

5. 发明申请

US20140114306A1 ABLATION CATHETER WITH BALLOON 有权
标题翻译：吸气管与气球
公开(公告)号：US20140114306A1
公开(公告)日：2014-04-24
申请号：US14123595
申请日：2012-06-08
申请人： Hiroyuki Harada , Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
发明人： Hiroyuki Harada , Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/0022 , A61B2018/00357 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00821
摘要： A balloon ablation catheter achieves reduction in diameter of the balloon upon balloon contraction and increased reliability of the thermocouple temperature sensor, which balloon ablation catheter is less likely to be influenced by the heating liquid discharged into the balloon and able to control the balloon surface temperature with high accuracy. The balloon ablation catheter includes a shaft wherein a lumen is formed; a balloon wherein the lumen communicates with the inside thereof; and a high-frequency-current-applying electrode formed by coiling a high-frequency-power-supplying lead wire around the shaft while sandwiching a temperature sensor lead wire between the high-frequency-power-supplying lead wire and the shaft such that the temperature sensor lead wire is fixed along the longitudinal direction of the shaft; wherein a thermocouple thermosensor is formed at the point where the high-frequency-power-supplying lead wire and the temperature sensor lead wire constituting the high-frequency-current-applying electrode contact with each other for the first time as seen from the posterior end side in the longitudinal direction.
摘要翻译：球囊消融导管在球囊收缩时实现球囊直径的减小，并且增加了热电偶温度传感器的可靠性，气球消融导管不太可能受到排放到球囊中的加热液体的影响，并且能够用高准确率。气囊消融导管包括其中形成内腔的轴; 气囊，其中内腔与其内部连通; 以及高频电流施加电极，其通过在高频供电引线和轴之间夹着温度传感器引线而将围绕轴的高频供电引线卷绕而形成，使得温度传感器引线沿轴的长度方向固定; 其特征在于，在构成所述高频电流施加电极的所述高频供电引线和所述温度传感器引线从所述后端观察时第一次形成热电偶热敏电阻侧纵向。

6. 发明申请

US20120065633A1 SHAFT FOR ABLATION CATHETER WITH BALLOON 有权
标题翻译：用于气球的导杆
公开(公告)号：US20120065633A1
公开(公告)日：2012-03-15
申请号：US13260807
申请日：2010-03-30
申请人： Takahiro Yagi , Motoki Takaoka , Akinori Matsukuma
发明人： Takahiro Yagi , Motoki Takaoka , Akinori Matsukuma
IPC分类号： A61B18/04
CPC分类号： A61B18/04 , A61B18/1492 , A61B2018/00166 , A61B2018/0022 , A61B2018/00404 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61B2018/046 , A61B2018/1472
摘要： The stirring efficiency of a heating liquid which is supplied to the balloon of a balloon-equipped ablation catheter is increased to quickly uniformize the surface temperature of the balloon, and air is prevented from remaining in the balloon-equipped ablation catheter to enhance the safety of treatment which uses the balloon-equipped ablation catheter. A shaft for a balloon-equipped ablation catheter, consisting of a single pipe, wherein the shaft has two lumens which communicate from the distal end to the proximal end of the shaft, a first lumen being a guide wire passage lumen which is provided in order to allow a guide wire to pass therethrough, the second lumen being a liquid supply lumen which is provided in order to supply liquid to the inside of the balloon of the balloon-equipped ablation catheter.
摘要翻译：提供给装有球囊的消融导管的球囊的加热液体的搅拌效率增加，以使球囊的表面温度快速均匀化，并且防止空气残留在装有球囊的消融导管中以提高安全性使用装有气球的消融导管的治疗。一种用于球囊装备的消融导管的轴，由单个管组成，其中所述轴具有从所述轴的远端连接到所述近端的两个腔，第一腔是依次设置的导丝通道腔，以允许导丝通过其中，第二内腔是液体供应腔，其被设置用于将液体供应到装有球囊的消融导管的球囊的内部。

7. 发明申请

US20120065624A1 GUIDEWIRE AND ABLATION CATHETER SYSTEM WITH BALLOON 有权
标题翻译：带气球的导轨和排气导管系统
公开(公告)号：US20120065624A1
公开(公告)日：2012-03-15
申请号：US13319701
申请日：2010-05-18
申请人： Akinori Matsukuma , Motoki Takaoka , Takahiro Yagi
发明人： Akinori Matsukuma , Motoki Takaoka , Takahiro Yagi
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61B18/1492 , A61B2017/22038 , A61B2018/00285 , A61M2025/09133 , A61M2025/09183
摘要： Provided is a guide wire, wherein a deformed portion formed by bending and/or curving the guide wire is located in the region of 20-100 mm from the tip in the longitudinal direction of the guide wire, and in the deformed portion, the shortest distance between the central axis in the longitudinal direction of the guide wire and a point that is the farthest in the direction perpendicular to the central axis is longer than or equal to the minimum inside diameter of a lumen of a catheter shaft of an ablation catheter with a balloon used in combination with the guide wire, and shorter than or equal to 40 mm.
摘要翻译：本发明提供一种引导线，其中通过弯曲和/或弯曲导丝而形成的变形部分位于与引导件的纵向方向上的尖端相距20-100mm的区域中，并且在变形部分中，最短引导线的纵向方向上的中心轴与垂直于中心轴的方向最远的点之间的距离大于或等于消融导管的导管轴的内腔的最小内径，与导丝组合使用的气囊，并且小于或等于40mm。

8. 发明申请

US20120059368A1 ABLATION CATHETER WITH BALLOON AND ABLATION CATHETER SYSTEM WITH BALLOON 有权
标题翻译：具有气球和气压导管系统的吸气管
公开(公告)号：US20120059368A1
公开(公告)日：2012-03-08
申请号：US13320053
申请日：2010-05-18
申请人： Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
发明人： Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
IPC分类号： A61B18/18 , A61B18/14
CPC分类号： A61B18/1492 , A61B18/082 , A61B18/1233 , A61B2018/00214 , A61B2018/0022 , A61B2018/00351 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00875 , A61B2018/046 , A61B2018/124
摘要： In order to perform balloon ablation and spot ablation by one ablation catheter without exchanging an ablation catheter body at the time of treatment by catheter ablation, an ablation catheter with a balloon is provided with a catheter shaft, a balloon which is mounted to the front end side in the longitudinal direction of the catheter shaft, a lumen which communicates with the balloon from the end face on the back end side in the abovementioned longitudinal direction, an in-balloon electrode and an in-balloon temperature sensor which are disposed in the balloon, and a front end electrode and a front end temperature sensor which are mounted in a front end region including the end face on the front end side in the abovementioned longitudinal direction.
摘要翻译：为了在通过导管消融治疗时不通过消融导管体进行一次消融导管进行球囊消融和斑点消融，具有球囊的消融导管设置有导管轴，气囊安装在前端在与上述长度方向的后端侧的端面与球囊连通的内腔，配置在气囊内的气囊内电极和气囊内温度传感器，以及前端电极和前端温度传感器，其安装在包括在前述纵向方向上的前端侧的端面的前端区域中。

9. 发明申请

US20120035604A1 STIRRING METHOD AND ABLATION CATHETER SYSTEM WITH BALLOON 有权
标题翻译：具有气泡的搅拌方法和排气导管系统
公开(公告)号：US20120035604A1
公开(公告)日：2012-02-09
申请号：US13260793
申请日：2010-03-30
申请人： Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
发明人： Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
IPC分类号： A61B18/04
CPC分类号： A61B18/04 , A61B2018/00577 , A61B2018/046
摘要： Provided is an ablation catheter system with a balloon which can improve the effect of therapy by ablation by eliminating variation in the surface temperature of a balloon in the ablation catheter with a balloon which cauterizes the tissue. An ablation catheter system with a balloon comprising a catheter shaft, a balloon fixed to the catheter shaft, a lumen which penetrates the catheter shaft in the direction of the long axis and communicates with the interior of the balloon, a heating electrode arranged in the balloon, a heating device which applies electrical energy to the heating electrode, and a vibration imparting device which imparts a vibration to the heating liquid by periodically repeating suction and ejection of the heating liquid from the lumen. Also provided is a stirring method for stirring the heating liquid by vibration wherein the vibration is imparted in such a manner that the value obtained by dividing the volume of the heating liquid being ejected toward the balloon by single ejection by the expansion volume of the balloon and then multiplying the quotient by 100 becomes 2-9.
摘要翻译：提供了一种具有气囊的消融导管系统，其可以通过消除烧蚀导管中的气球的表面温度的变化来改善烧蚀治疗的效果，其中烧灼组织的球囊。一种具有球囊的消融导管系统，包括导管轴，固定到导管轴的球囊，沿长轴方向穿透导管轴并与球囊内部连通的内腔，布置在球囊内的加热电极，向加热电极施加电能的加热装置，以及通过周期性地重复地从内腔抽吸和喷射加热液体而向加热液体施加振动的振动赋予装置。还提供了一种用于通过振动来搅拌加热液体的搅拌方法，其中施加振动，使得通过将通过气球的膨胀体积单次喷射朝向气球喷射的加热液体的体积所得到的值和然后将商乘以100变为2-9。

10. 发明授权

US09144458B2 Ablation catheter with balloon and ablation catheter system with balloon 有权
标题翻译：消融导管与球囊和消融导管系统与气球
公开(公告)号：US09144458B2
公开(公告)日：2015-09-29
申请号：US13320053
申请日：2010-05-18
申请人： Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
发明人： Motoki Takaoka , Akinori Matsukuma , Takahiro Yagi
IPC分类号： A61B18/14 , A61B18/08 , A61B18/00 , A61B18/12 , A61B18/04
CPC分类号： A61B18/1492 , A61B18/082 , A61B18/1233 , A61B2018/00214 , A61B2018/0022 , A61B2018/00351 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00875 , A61B2018/046 , A61B2018/124
摘要： In order to perform balloon ablation and spot ablation by one ablation catheter without exchanging an ablation catheter body at the time of treatment by catheter ablation, an ablation catheter with a balloon is provided with a catheter shaft, a balloon which is mounted to the front end side in the longitudinal direction of the catheter shaft, a lumen which communicates with the balloon from the end face on the back end side in the abovementioned longitudinal direction, an in-balloon electrode and an in-balloon temperature sensor which are disposed in the balloon, and a front end electrode and a front end temperature sensor which are mounted in a front end region including the end face on the front end side in the abovementioned longitudinal direction.
摘要翻译：为了在通过导管消融治疗时不通过消融导管体进行一次消融导管进行球囊消融和斑点消融，具有球囊的消融导管设置有导管轴，气囊安装在前端在与上述长度方向的后端侧的端面与球囊连通的内腔，配置在气囊内的气囊内电极和气囊内温度传感器，以及前端电极和前端温度传感器，其安装在包括在前述纵向方向上的前端侧的端面的前端区域中。

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