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1. 发明授权

US5743875A Catheter shaft with an oblong transverse cross-section 失效
公开(公告)号：US5743875A
公开(公告)日：1998-04-28
申请号：US742689
申请日：1996-11-04
申请人： Motasim M. Sirhan , Jovito L. Fernando, Sr. , Troy L. Thornton , Patrick K. Campbell , Eric Williams , Lawrence D. Wasicek
发明人： Motasim M. Sirhan , Jovito L. Fernando, Sr. , Troy L. Thornton , Patrick K. Campbell , Eric Williams , Lawrence D. Wasicek
IPC分类号： A61L29/04 , A61M25/00 , A61M29/02 , A61M29/00
CPC分类号： A61M25/104 , A61L29/041 , A61M25/0023 , A61M25/0043 , A61M2025/0004 , A61M2025/0034 , A61M2025/0037 , A61M2025/0039 , A61M2025/0063 , A61M2025/0177 , A61M2025/0183 , A61M2025/1063 , A61M2025/1097 , A61M25/0009 , A61M25/0021 , A61M25/0029
摘要： A balloon dilatation catheter having a catheter shaft with an oblong transverse cross-section with one transverse dimension in a first direction being significantly larger than a second transverse dimension in a direction perpendicular to the first direction. The first dimension is about 1.1 to about 3 times greater, preferably about 1.2 to about 2.5 times greater than the second dimension. In one embodiment, a length of the distal shaft section has inner and outer tubular members where about 30% to not more than about 90% of the inner periphery of the outer tubular member takes the shape of and is secured to the exterior of the inner tubular member. In another embodiment the flexible distal shaft section is an extruded section having an oval or elliptical transverse cross-section. Preferably a pseudoelastic hypotube of NiTi alloy defines at least part of the inflation lumen within the catheter shaft. In another embodiment of the invention the proximal shaft of the catheter has an inner and outer tubular member.

2. 发明授权

US6027475A Catheter shaft with an oblong transverse cross-section 失效
公开(公告)号：US6027475A
公开(公告)日：2000-02-22
申请号：US778662
申请日：1997-01-02
申请人： Motasim M. Sirhan , Jovito L. Fernando, Sr. , Troy L. Thornton , Patrick K. Campbell , Eric Williams , Lawrence D. Wasicek
发明人： Motasim M. Sirhan , Jovito L. Fernando, Sr. , Troy L. Thornton , Patrick K. Campbell , Eric Williams , Lawrence D. Wasicek
IPC分类号： A61L29/04 , A61M25/00 , A61M29/02 , A61M29/00
CPC分类号： A61M25/104 , A61L29/041 , A61M25/0023 , A61M25/0043 , A61M2025/0004 , A61M2025/0034 , A61M2025/0037 , A61M2025/0039 , A61M2025/0063 , A61M2025/0177 , A61M2025/0183 , A61M2025/1063 , A61M2025/1097 , A61M25/0009 , A61M25/0021 , A61M25/0029
摘要： A balloon dilatation catheter having a catheter shaft with an oblong transverse cross-section with one transverse dimension in a first direction being significantly larger than a second transverse dimension in a direction perpendicular to the first direction. The first dimension is about 1.1 to about 3 times greater, preferably about 1.2 to about 2.5 times greater than the second dimension. In one embodiment, a length of the distal shaft section has inner and outer tubular members where about 30% to not more than about 90% of the inner periphery of the outer tubular member takes the shape of and is secured to the exterior of the inner tubular member. In another embodiment the flexible distal shaft section is an extruded section having an oval or elliptical transverse cross-section. Preferably a pseudoelastic hypotube of NiTi alloy defines at least part of the inflation lumen within the catheter shaft. In another embodiment of the invention the proximal shaft of the catheter has an inner and outer tubular member.

3. 发明授权

US6013069A Catheter shaft with an oblong transverse cross-section 失效
标题翻译：导管轴长方形横截面
公开(公告)号：US6013069A
公开(公告)日：2000-01-11
申请号：US63874
申请日：1998-04-21
申请人： Motasim M. Sirhan , Jovito L. Fernando, Sr. , Troy L. Thornton , Patrick K. Campbell , Eric Williams , Lawrence D. Wasicek
发明人： Motasim M. Sirhan , Jovito L. Fernando, Sr. , Troy L. Thornton , Patrick K. Campbell , Eric Williams , Lawrence D. Wasicek
IPC分类号： A61L29/04 , A61M25/00 , A61M29/02 , A61M29/00
CPC分类号： A61M25/104 , A61L29/041 , A61M25/0023 , A61M25/0043 , A61M2025/0004 , A61M2025/0034 , A61M2025/0037 , A61M2025/0039 , A61M2025/0063 , A61M2025/0177 , A61M2025/0183 , A61M2025/1063 , A61M2025/1097 , A61M25/0009 , A61M25/0021 , A61M25/0029
摘要： A balloon dilatation catheter having a catheter shaft with an oblong transverse cross-section with one transverse dimension in a first direction being significantly larger than a second transverse dimension in a direction perpendicular to the first direction. The first dimension is about 1.1 to about 3 times greater, preferably about 1.2 to about 2.5 times greater than the second dimension. In one embodiment, a length of the distal shaft section has inner and outer tubular members where about 30% to not more than about 90% of the inner periphery of the outer tubular member takes the shape of and is secured to the exterior of the inner tubular member. In another embodiment the flexible distal shaft section is an extruded section having an oval or elliptical transverse cross-section. Preferably a pseudoelastic hypotube of NiTi alloy defines at least part of the inflation lumen within the catheter shaft. In another embodiment of the invention the proximal shaft of the catheter has an inner and outer tubular member.
摘要翻译：具有导管轴的球囊扩张导管，其具有在第一方向上具有一个横向尺寸的长圆形横截面，其显着大于在垂直于第一方向的方向上的第二横向尺寸。第一尺寸比第二尺寸大1.1倍至3倍，优选约1.2至约2.5倍。在一个实施例中，远侧轴部分的长度具有内部和外部管状部件，其中外部管状部件的内周边的约30％至不超过约90％的形状为固定在外部管状部件的外部管状构件。在另一个实施例中，柔性远端轴部分是具有椭圆形或椭圆形横截面的挤压部分。优选地，NiTi合金的假弹性海波管限定了导管轴内的充气腔的至少一部分。在本发明的另一个实施例中，导管的近侧轴具有内部和外部管状构件。

4. 发明授权

US5571094A Guidewire replacement device 失效
公开(公告)号：US5571094A
公开(公告)日：1996-11-05
申请号：US168571
申请日：1993-12-16
申请人： Motasim M. Sirhan
发明人： Motasim M. Sirhan
IPC分类号： A61M25/01 , A61M25/09 , A61M29/02 , A61M25/00
CPC分类号： A61M25/0172 , A61M25/104 , A61M2025/0063 , A61M2025/0183
摘要： A guidewire replacement device having an elongated catheter shaft with an inner lumen extending within the catheter shaft, a proximal guidewire port spaced at least 1 cm from the distal end of the catheter which is in fluid communication with the inner lumen and a distal guidewire port in the distal end of the catheter which is also in fluid communication with the inner lumen. The proximal end of an in-place guidewire is inserted through the distal guidewire port and advanced through the inner lumen until the proximal end of the guidewire extends through the proximal guidewire port. The exchange device is advanced over the guidewire until the distal end of the exchange device is seated within the proximal guidewire port in the readily exchangeable dilatation catheter. With the distal end of the exchange device well seated within the proximal guidewire port of the dilatation catheter, the in-place guidewire can be withdrawn from the patient. A replacement guidewire is advanced through the inner lumen of the exchange device until it exits the distal guidewire port of the exchange device into the inner guidewire receiving lumen of the dilatation catheter. Once the replacement guidewire is properly placed, the exchange device can then be withdrawn from the patient.

5. 发明授权

US06451043B1 Method of using a readily exchangeable perfusion dilatation catheter 失效
标题翻译：使用易于更换的灌注扩张导管的方法
公开(公告)号：US06451043B1
公开(公告)日：2002-09-17
申请号：US08751353
申请日：1996-11-18
申请人： Peter R. McInnes , Motasim M. Sirhan
发明人： Peter R. McInnes , Motasim M. Sirhan
IPC分类号： A61M2510
CPC分类号： A61M25/104 , A61M25/09 , A61M2025/0063 , A61M2025/0183 , A61M2025/107 , A61M2025/1097
摘要： A perfusion-type dilatation catheter which can be rapidly exchanged for another catheter without the need for exchange wires or guidewire extension wire. The dilatation catheter has an elongated catheter body with a distal guidewire port in the distal end of the catheter and a proximal guidewire port at least 10 cm but not more than 50 cm from the distal port. The catheter body has a first inflation lumen which extends from the proximal end of the catheter body to the interior of a dilatation balloon adjacent the distal end of the catheter body. A second, much shorter inner lumen is disposed between the proximal and distal guidewire ports and is adapted to slidably receive a guidewire. A plurality of perfusion ports are provided both proximal and distal to the balloon which are in fluid communication with the second inner lumen so that when the balloon is inflated within a patient's vascular system, blood will flow through the proximal perfusion ports and the second inner lumen and out the distal perfusion ports to minimize ischemic conditions distal to the catheter. A stiffening member is disposed within. the catheter body proximal to the proximal guidewire port to provide improved pushability. The distal portion of the inflation lumen should have a transverse cross-sectional area of about 3 to about 20×10−5 inch2 and should not be greater than one-third the cross-sectional area of the perfusion lumen.
摘要翻译：一种灌注式扩张导管，可以快速更换另一种导管，无需更换电线或导丝延长线。扩张导管具有细长的导管主体，导管主体具有在导管的远端中的远端导丝端口，并且距离远端端口至少10厘米但不超过50厘米的近端导丝端口。导管主体具有从导管主体的近端延伸到邻近导管主体远端的扩张球囊的内部的第一充气腔。第二，更短的内腔设置在近端和远端导丝端口之间，并且适于滑动地容纳导丝。多个灌注端口被提供在球囊的近端和远端，其与第二内腔流体连通，使得当气囊在患者的血管系统内被充气时，血液将流过近端灌注端口和第二内腔并远离灌注口，以尽量减少导管远端的缺血状况。一个加强件被放置在内部。导管主体靠近近端导丝端口以提供改进的可推动性。充气腔的远端部分应具有约3至约20×10 -5英寸2的横截面积，并且不应大于灌注腔的横截面面积的三分之一。

6. 发明授权

US5516336A Readily exchangeable perfusion dilatation catheter 失效
公开(公告)号：US5516336A
公开(公告)日：1996-05-14
申请号：US183574
申请日：1994-01-18
申请人： Peter R. McInnes , Motasim M. Sirhan
发明人： Peter R. McInnes , Motasim M. Sirhan
IPC分类号： A61M29/02 , A61M25/10
CPC分类号： A61M25/104 , A61M2025/0063 , A61M2025/0183 , A61M2025/107 , A61M2025/1097 , A61M25/09
摘要： A perfusion-type dilatation catheter which can be rapidly exchanged for another catheter without the need for exchange wires or guidewire extension wires. The dilatation catheter has an elongated catheter body with a distal guidewire port in the distal end of the catheter and a proximal guidewire port at least 10 cm but not more than 50 cm from the distal port. The catheter body has a first inflation lumen which extends from the proximal end of the catheter body to the interior of a dilatation balloon adjacent the distal end of the catheter body. A second, much shorter inner lumen is disposed between the proximal and distal guidewire ports and is adapted to slidably receive a guidewire. A plurality of perfusion ports are provided both proximal and distal to the balloon which are in fluid communication with the second inner lumen so that when the balloon is inflated within a patient's vascular system, blood will flow through the proximal perfusion ports and the second inner lumen and out the distal perfusion ports to minimize ischemic conditions distal to the catheter. A stiffening member is disposed within the catheter body proximal to the proximal guidewire port to provide improved pushability. The distal portion of the inflation lumen should have a transverse cross-sectional area of about 3 to about 20.times.10.sup.-5 inch.sup.2 and should not be greater than one-third the cross-sectional area of the perfusion lumen.

7. 发明授权

US5496275A Low profile dilatation catheter 失效
标题翻译：低调扩张导管
公开(公告)号：US5496275A
公开(公告)日：1996-03-05
申请号：US192065
申请日：1994-02-04
申请人： Motasim M. Sirhan , Jovito L. Fernando
发明人： Motasim M. Sirhan , Jovito L. Fernando
IPC分类号： A61M25/00 , A61M29/02 , A61M29/00
CPC分类号： A61M25/104 , A61M25/0043 , A61M2025/0004 , A61M2025/0034 , A61M2025/0039 , A61M2025/0063 , A61M2025/0177 , A61M2025/0183 , A61M2025/1063 , A61M2025/1097 , A61M25/0009 , A61M25/0021 , A61M25/0029
摘要： An intravascular catheter, such as a balloon dilatation catheter, which has a distal section wherein a small dimensioned distal section of an outer tubular member is bonded to an inner tubular member over a significant portion thereof to provide a catheter shaft having small transverse dimensions and improved flexibility with little or no loss is pushability. The catheter construction can be employed in a wide variety of catheters.
摘要翻译：一种血管内导管，例如球囊扩张导管，其具有远端部分，其中外部管状部件的小尺寸的远侧部分在其重要部分上结合到内部管状部件，以提供具有小的横向尺寸的导管轴并且改进灵活性很少或没有损失是可推性。导管结构可用于各种导管。

8. 发明授权

US5533968A Low profile catheter with expandable outer tubular member 失效
标题翻译：具有可扩张的外管状构件的低剖面导管
公开(公告)号：US5533968A
公开(公告)日：1996-07-09
申请号：US250809
申请日：1994-05-27
申请人： Ketan P. Muni , Motasim M. Sirhan
发明人： Ketan P. Muni , Motasim M. Sirhan
IPC分类号： A61F2/958 , A61L29/04 , A61M25/00 , A61M29/02 , A61M29/00
CPC分类号： A61M25/104 , A61L29/041 , A61M25/0029 , A61M25/0043 , A61M25/1027 , A61M2025/0004 , A61M2025/0034 , A61M2025/0039 , A61M2025/0063 , A61M2025/0079 , A61M2025/0177 , A61M2025/0183 , A61M2025/1059 , A61M2025/1063 , A61M2025/1079 , A61M2025/1084 , A61M2025/1097 , A61M25/0009 , A61M25/0021 , A61M25/10 , A61M25/1029
摘要： An intravascular catheter such as a dilatation catheter for angioplasty with a catheter shaft having an outer tubular member with an expandable distal section which expands elasticly upon the introduction of fluid under a pressure within a first pressure range to a larger diameter and which contracts by elastic recoil upon the withdrawal of the inflation fluid. The expandable distal section is relatively noncompliant at pressures above the first pressure range. Preferably, the dilatation catheter has an inflatable member or balloon disposed distal to the expandable distal section which is formed of the same polymeric material as the expandable distal section and is in fluid communication with the expandable inner lumen within the expandable distal section. In one preferred embodiment the catheter has a distal section which includes an outer tubular member bonded or otherwise secured (e.g. heat bonding or adhesive bonding) to an inner tubular member over a length to provide a catheter shaft having small transverse dimensions and improved flexibility with no loss in pushability. The unbonded or unsecured portion of the outer tubular member is expandable and when expanded forms with the inner tubular member an inflation lumen in fluid communication with the interior of the balloon.
摘要翻译：一种血管内导管，例如用于血管成形术的扩张导管，其具有导管轴，所述导管轴具有外管状构件，所述外管状构件具有可扩张的远端部分，所述外管状构件在第一压力范围内的压力下引入流体时弹性膨胀并且通过弹性反冲撤回通胀流体后。可膨胀的远端部分在高于第一压力范围的压力下是相对不符合的。优选地，扩张导管具有可膨胀构件或球囊，其设置在可扩张远端部分的远侧，该可膨胀远端部分由与可扩张远侧部分相同的聚合物材料形成并且与可扩张远端部分内的可扩张内腔流体连通。在一个优选实施例中，导管具有远端部分，该远端部分包括外部管状部件，该外部管状部件在一段长度上与内部管状部件接合或以其它方式固定（例如热粘合或粘合），以提供具有小横向尺寸和改善柔性的导管轴，可推力丧失。外管状构件的未粘合或不固定的部分是可膨胀的，并且当与内管状构件膨胀时，膨胀腔与气囊的内部流体连通。

9. 发明授权

US5195971A Perfusion type dilatation catheter 失效
标题翻译：灌注型扩张导管
公开(公告)号：US5195971A
公开(公告)日：1993-03-23
申请号：US833537
申请日：1992-02-10
申请人： Motasim M. Sirhan
发明人： Motasim M. Sirhan
IPC分类号： A61M29/02
CPC分类号： A61M25/104 , A61M2025/1079 , A61M2025/1095
摘要： A dilatation catheter is described wherein a primary perfusion port is provided adjacent the proximal end of the inflatable member having a transverse cross-sectional area which is dimensioned to provide the bulk of the perfusion flow through the catheter. The primary perfusion port is offset from the guidewire receiving lumen which extends through the catheter shaft.
摘要翻译：描述了一种扩张导管，其中主要灌注端口邻近可膨胀构件的近端设置，具有横向横截面积，该横截面面积的尺寸被设计成提供通过导管的大部分灌注流。主要灌注口从延伸穿过导管轴的导丝接收腔偏移。

10. 发明授权

US5709658A Rapid exchange type over-the-wire catheter 失效
公开(公告)号：US5709658A
公开(公告)日：1998-01-20
申请号：US602681
申请日：1996-02-16
申请人： Motasim M. Sirhan , Robert F. Kotmel , Susan M. Feltovich
发明人： Motasim M. Sirhan , Robert F. Kotmel , Susan M. Feltovich
IPC分类号： A61M29/02 , A61M29/00
CPC分类号： A61M25/104 , A61M2025/0183
摘要： An intraluminal catheter, particularly a dilatation catheter for PTCA procedures, which is adapted for rapid exchange during an intraluminal procedure and which also allows for the exchange of the guidewire without loss of access to the intraluminal region about the distal end of the catheter. The catheter has a main guidewire lumen which extends essentially the length of the catheter and a guidewire extension lumen which extends proximally from the main guidewire lumen and is at least in part offset and parallel to the main guidewire lumen. A portion of the catheter shaft which defines at least part of the main guidewire lumen has a first slit from the proximal end of the catheter to the intersection between the extension lumen and the main guidewire lumen and a second lumen which extends from a proximal guidewire port in the guidewire extension lumen to a port in the distal end of the catheter. Also disclosed is an adapter having a slit which is continuous with the slit in the proximal extremity of the catheter shaft which facilitates separation of the guidewire and the catheter when the adapter is fixed to the proximal end of the catheter shaft.

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