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1. 发明授权

US06511508B1 Surgical correction of human eye refractive errors by active composite artificial muscle implants 失效
$Surgical correction of human eye refractive errors by active composite artificial muscle implants$
标题翻译：通过活性复合人造肌植入手术矫正人眼屈光不正
公开(公告)号：US06511508B1
公开(公告)日：2003-01-28
申请号：US09633023
申请日：2000-08-04
申请人： Mohsen Shahinpoor , Parsa Shahinpoor , David Soltanpour
发明人： Mohsen Shahinpoor , Parsa Shahinpoor , David Soltanpour
IPC分类号： A61F214
CPC分类号： A61F2/147 , A61B17/04 , A61F2002/0894 , A61N2/02
摘要： Surgical correction of human eye refractive errors such as presbyopia, hyperopia, myopia, and stigmatism by using transcutaneously inductively energized artificial muscle implants to either actively change the axial length and the anterior curvatures of the eye globe. This brings the retina/macula region to coincide with the focal point. The implants use transcutaneously inductively energized scleral constrictor bands equipped with composite artificial muscle structures. The implants can induce enough accommodation of a few diopters, to correct presbyopia, hyperopia, and myopia on demand. In the preferred embodiment, the implant comprises an active sphinctering smart band to encircle the sclera, preferably implanted under the conjunctiva and under the extraocular muscles to uniformly constrict the eye globe, similar to a scleral buckle band for surgical correction of retinal detachment, to induce active temporary myopia (hyperopia) by increasing (decreasing) the active length of the globe. In another embodiment, multiple and specially designed constrictor bands can be used to enable surgeons to correct stigmatism. The composite artificial muscles are either resilient composite shaped memory alloy-silicone rubber implants in the form of endless active scleral bands, electroactive ionic polymeric artificial muscle structures, electrochemically contractile endless bands of ionic polymers such as polyacrylonitrile (PAN), thermally contractile liquid crystal elastomer artificial muscle structures, magnetically deployable structures or solenoids or other deployable structures equipped with smart materials such as preferably piezocerams, piezopolymers, electroactive and eletrostrictive polymers, magnetostrictive materials, and electro or magnetorheological materials.
摘要翻译：通过使用经皮诱导的人工肌肉植入物来主动改变眼球的轴向长度和前曲率，进行人眼屈光不正的手术矫正，例如老花眼，远视，近视和耻骨。这使得视网膜/黄斑区域与焦点相一致。植入物使用配备有复合人造肌肉结构的经皮诱导的巩膜收缩带。植入物可以诱导足够的几个屈光度适应，根据需要矫正老花眼，远视和近视。在优选实施例中，植入物包括活动性括约肌智能带，以包围巩膜，优选植入在结膜下和眼外肌下方以均匀地收缩眼球，类似于用于手术矫正视网膜脱离的巩膜带扣诱导通过增加（减少）全球活跃的长度来激活临时近视（远视）。在另一个实施例中，可以使用多个和特别设计的收缩带来使外科医生能够矫正假象。复合人造肌是弹性复合形状记忆合金 - 硅橡胶植入物，其形式为无限活性巩膜带，电活性离子聚合物人造肌结构，电化学收缩的离子聚合物如聚丙烯腈（PAN），热收缩液晶弹性体人造肌肉结构，磁性可展开结构或螺线管或其他配备有智能材料的可部署结构，例如优选压电陶瓷，压电聚合物，电活性和电致伸缩聚合物，磁致伸缩材料和电磁流变材料。

2. 发明申请

US20120116505A1 SYSTEM AND DEVICE FOR CORRECTING HYPEROPIA, MYOPIA AND PRESBYOPIA 审中-公开
标题翻译：用于校正HYPEROPIA，MYOPIA和PRESBYOPIA的系统和设备
公开(公告)号：US20120116505A1
公开(公告)日：2012-05-10
申请号：US13353319
申请日：2012-01-19
申请人： Mohsen Shahinpoor , David Soltanpour , Parsa Shahinpoor
发明人： Mohsen Shahinpoor , David Soltanpour , Parsa Shahinpoor
IPC分类号： A61F2/14
CPC分类号： A61F2/147
摘要： The present invention includes an ophthalmic device and system of mounting for correcting hyperopia, myopia and presbyopia. The present invention includes a limbus ring mountable in an encircling relation to a central optic zone of a cornea on a limbus annulus surrounding the cornea. In the limbus ring defines a substantially annular toroid defining a first average diameter that is selectable and has a hydrophilic coating disposed thereon. The inner radius of the limbus ring is selectable such that, upon mounting on the limbus annulus, the limbus ring causes the limbus annulus to contract or expand thereby causing the curvature of the cornea and the eye length to increase or decrease. The mounting system of the present invention is adapted to receive a limbus ring and further adapted to selectively place the limbus ring on a limbus annulus.
摘要翻译：本发明包括眼科装置和用于矫正远视，近视和远视的安装系统。本发明包括一个角膜缘环，其可围绕着角膜的角膜缘环上的角膜的中心光学区域环绕安装。在角膜缘环中限定了基本上环形的环形，其限定了可选择的第一平均直径并且具有设置在其上的亲水性涂层。角膜缘环的内半径是可选择的，使得在安装在角膜缘环上时，边缘环使得角膜缘环收缩或膨胀，从而导致角膜的弯曲和眼睛的长度增加或减小。本发明的安装系统适于接收边缘环，还适于选择性将角膜缘环放置在角膜缘环上。

3. 发明授权

US07090696B2 Surgical correction of human eye refractive errors by active composite artificial muscle implants 有权
$Surgical correction of human eye refractive errors by active composite artificial muscle implants$
标题翻译：通过活性复合人造肌植入手术矫正人眼屈光不正
公开(公告)号：US07090696B2
公开(公告)日：2006-08-15
申请号：US10345583
申请日：2003-01-16
申请人： Mohsen Shahinpoor , Parsa Shahinpoor , David Soltanpour
发明人： Mohsen Shahinpoor , Parsa Shahinpoor , David Soltanpour
IPC分类号： A61F2/14
CPC分类号： A61F2/147 , A61B17/04 , A61F2002/0894 , A61N2/02
摘要： Correction of eye refractive errors like presbyopia, hyperopia, myopia, and astigmatism using either pre-tensioned or transcutaneously energized artificial muscle implants to change the axial length and anterior curvatures of the eye globe by bringing the retina/macula region to coincide with the focal point. The implants are scleral constrictor bands, segments or ribs for inducing accommodation of a few diopters, to correct refractive errors on demand or automatically. The implant comprises an active sphinctering band encircling the sclera, implanted under the conjunctiva and under the extraocular muscles to uniformly constrict the eye globe, to induce active temporary myopia (hyperopia) by increasing(decreasing) the length and curvature of the globe. Multiple and specially designed constrictor bands enable surgeons to correct astigmatism. The artificial muscles comprise materials such as composite magnetic shape memory (MSM), heat shrink, shape memory alloy-silicone rubber, electroactive ionic polymeric artificial muscles or etectrochemically contractile ionic polymers bands.
摘要翻译：使用预张紧或经皮激发的人造肌植入物矫正眼睛屈光不正，如老花眼，远视，近视和散光，以通过使视网膜/黄斑区域与焦点重合来改变眼球的轴向长度和前曲率。植入物是巩膜收缩带，段或肋，用于诱导几个屈光度的适应，以按需或自动地校正屈光不正。植入物包括环绕巩膜的活动括约肌带，植入结膜下和眼外肌下，以均匀地收缩眼球，通过增加（减小）球体的长度和曲率来诱发活动的临时近视（远视）。多个专门设计的收缩带使外科医生能矫正散光。人造肌肉包括诸如复合磁形状记忆（MSM），热收缩，形状记忆合金 - 硅橡胶，电活性离子聚合物人造肌或电化学收缩离子聚合物带的材料。

4. 发明申请

US20060167422A1 Heat Shrink Scleral Band With Custom-Made Buckle For Retinal Detachment Surgery 审中-公开
标题翻译：热收缩巩膜带定制扣环视网膜脱离术
公开(公告)号：US20060167422A1
公开(公告)日：2006-07-27
申请号：US10707662
申请日：2003-12-30
申请人： Mohsen Shahinpoor , David Soltanpour , Parsa Shahinpoor
发明人： Mohsen Shahinpoor , David Soltanpour , Parsa Shahinpoor
IPC分类号： A61M35/00 , A61F2/16
CPC分类号： A61F9/00727
摘要： Discussed is a method and apparatus of correcting retinal detachments by heat-shrinking a specially designed scleral band equipped with a snap-on custom-made buckle for scleral indentation over the retinal tear region. The heat shrink band is made from a heat shrink material such as a polymer or an alloy and is equipped with a custom-made buckle to perfectly fit the topological geometry of the retinal detachment region over the underlying choroid and the sclera, the conjunctiva and within the Tenon's space wherein the band is heat shrunk to create a perfect buckle over the retinal tear region to reattach the retina to the choroid and cause absorption of the subretinal fluid. Conventional, laser, microwave, Joule or radio-frequency (RF) heating means are also discussed.
摘要翻译：讨论了通过热收缩专门设计的巩膜带的矫正视网膜脱离的方法和装置，所述巩膜带配备有卡扣定制带扣，用于视网膜撕裂区域上的巩膜压痕。热收缩带由诸如聚合物或合金的热收缩材料制成，并且配备有定制的扣环，以完美地适应视网膜脱离区域在下面的脉络膜和巩膜，结膜上和内部的视网膜脱离区域的拓扑几何形状 Tenon的空间，其中带被热收缩以在视网膜撕裂区域上产生完美的扣环，以将视网膜重新附着到脉络膜并引起视网膜下液体的吸收。还讨论了传统的激光，微波，焦耳或射频（RF）加热装置。

5. 发明申请

US20080177383A1 System and Device for Correcting Hyperopia and Presbyopia 有权
标题翻译：用于矫正远视和老花眼的系统和装置
公开(公告)号：US20080177383A1
公开(公告)日：2008-07-24
申请号：US11626774
申请日：2007-01-24
申请人： Mohsen Shahinpoor , David Soltanpour , Parsa Shahinpoor
发明人： Mohsen Shahinpoor , David Soltanpour , Parsa Shahinpoor
IPC分类号： A61F2/14
CPC分类号： A61F2/147
摘要： The present invention includes an ophthalmic device and system of mounting for correcting hyperopia and presbyopia. The present invention includes a limbus ring mountable in an encircling relation to a central optic zone of a cornea on a limbus annulus surrounding the cornea. In the limbus ring defines a substantially annular toroid defining a first average diameter that is selectable and has a hydrophilic coating disposed thereon. The inner radius of the limbus ring is selectable such that, upon mounting on the limbus annulus, the limbus ring causes the limbus annulus to contract thereby causing the curvature of the cornea and the eye length to increase. The mounting system of the present invention is adapted to receive a limbus ring and further adapted to selectively place the limbus ring on a limbus annulus.
摘要翻译：本发明包括用于矫正远视和老花眼的眼科装置和安装系统。本发明包括一个角膜缘环，其可围绕着角膜的角膜缘环上的角膜的中心光学区域环绕安装。在角膜缘环中限定了基本上环形的环形，其限定了可选择的第一平均直径并且具有设置在其上的亲水性涂层。角膜缘环的内半径是可选择的，使得在安装在边缘环上时，边缘环会导致角膜缘环收缩，从而导致角膜的弯曲和眼睛的长度增加。本发明的安装系统适于接收边缘环，还适于选择性将角膜缘环放置在角膜缘环上。

6. 发明授权

US06682500B2 Synthetic muscle based diaphragm pump apparatuses 失效
公开(公告)号：US06682500B2
公开(公告)日：2004-01-27
申请号：US09841191
申请日：2001-04-25
申请人： David Soltanpour , Mohsen Shahinpoor
发明人： David Soltanpour , Mohsen Shahinpoor
IPC分类号： A61M500
CPC分类号： A61F9/00781 , A61F9/0017 , A61M1/0023 , A61M5/14276 , A61M5/14586 , A61M5/14593 , A61M2205/0244 , A61M2205/0283 , A61M2210/0612 , F04B43/04 , F04B43/043 , Y10S977/733
摘要： Implantable, pressure adjustable diaphragm pump systems which are scalable and are characterized by a common type of actuating mechanism. The pumps may be inductively and transcutaneously powered via adjacent, mutually inductive electromagnetic coils. Alternatively the pumps may be effectively “self” powered using a synthetic muscle attached to a local bending or twisting force. The pumps may be used in a range of applications from mechanical applications to medical applications such as intraocular pressure control for glaucoma patients, bodily fluid drainage control, and drug delivery systems. These pump systems each include a pumping chamber having an anterior end attached to an implantable influent conduit. In the case of an ocular pressure control device, the influent conduit is inserted into the anterior chamber of the eye. A flexing ionic polymer conductor composite IPCC synthetic muscle, which is a type of ionic polymer metal composite (IPMC) synthetic muscle, functions as the primary actuator. The posterior end of the pumping chamber is connected to an effluent or drainage conduit, which may drain bodily fluids or dispense drugs to an area of the body. A key feature of the invention is the self or secondary power generation system in the form of a much larger piece of IPCC synthetic muscle which, in the case of glaucoma prevention systems, may be placed on the globe surface (sclera) of the eye and attached to and secured by the extraocular muscles of the eye. An alternative external power system includes a biocompatible induction coil with gold wire armature that can be transcutanously activated, adjusted, and computer-interrogated and controlled by a surgeon. The device of the invention is further equipped with a pair of adjustable variable flow valves placed at the juncture of the inlet and effluent conduits with the pumping chamber. The valves are used to regulate fluid flow through the pumping chamber. A pressure regulating system including a pressure sensor and pump controlling microprocessor may also be used with the inventive system.

7. 发明授权

US08123803B2 System and device for correcting hyperopia and presbyopia 有权
标题翻译：用于矫正远视和老花眼的系统和装置
公开(公告)号：US08123803B2
公开(公告)日：2012-02-28
申请号：US11626774
申请日：2007-01-24
申请人： Mohsen Shaninpoor , David Soltanpour , Parsa Shahinpoor
发明人： Mohsen Shaninpoor , David Soltanpour , Parsa Shahinpoor
IPC分类号： A61F2/14
CPC分类号： A61F2/147
摘要： The present invention includes an ophthalmic device and system of mounting for correcting hyperopia and presbyopia. The present invention includes a limbus ring mountable in an encircling relation to a central optic zone of a cornea on a limbus annulus surrounding the cornea. In the limbus ring defines a substantially annular toroid defining a first average diameter that is selectable and has a hydrophilic coating disposed thereon. The inner radius of the limbus ring is selectable such that, upon mounting on the limbus annulus, the limbus ring causes the limbus annulus to contract thereby causing the curvature of the cornea and the eye length to increase. The mounting system of the present invention is adapted to receive a limbus ring and further adapted to selectively place the limbus ring on a limbus annulus.
摘要翻译：本发明包括用于矫正远视和老花眼的眼科装置和安装系统。本发明包括一个角膜缘环，其可围绕着角膜的角膜缘环上的角膜的中心光学区域环绕安装。在角膜缘环中限定了基本上环形的环形，其限定了可选择的第一平均直径并且具有设置在其上的亲水性涂层。角膜缘环的内半径是可选择的，使得在安装在边缘环上时，边缘环会导致角膜缘环收缩，从而导致角膜的弯曲和眼睛的长度增加。本发明的安装系统适于接收边缘环，还适于选择性将角膜缘环放置在角膜缘环上。

8. 发明授权

US07850951B2 Synthetic muscle-based multi-powered active contact lens 失效
标题翻译：合成肌肉多动力隐形眼镜
公开(公告)号：US07850951B2
公开(公告)日：2010-12-14
申请号：US11358530
申请日：2006-02-21
申请人： Mohsen Shahinpoor , David Soltanpour
发明人： Mohsen Shahinpoor , David Soltanpour
IPC分类号： A61K8/721
CPC分类号： G02C7/04 , G02B1/043
摘要： A novel active contact lens system configured to allow the wearer to alter the corrective features of the contact lens by means of a biasing force. The biasing force can, for example, be different eye drop solutions having different pH levels.
摘要翻译：一种新颖的主动隐形眼镜系统，其被配置为允许穿戴者借助于偏压力改变隐形眼镜的矫正特征。例如，偏置力可以是具有不同pH水平的不同的滴眼液。

9. 发明授权

US07625404B2 Surgical correction of ptosis by polymeric artificial muscles 有权
标题翻译：聚合人造肌的下垂手术矫正
公开(公告)号：US07625404B2
公开(公告)日：2009-12-01
申请号：US11318665
申请日：2005-12-24
申请人： Mohsen Shahinpoor , David Soltanpour
发明人： Mohsen Shahinpoor , David Soltanpour
IPC分类号： A61F2/14 , A61F2/08 , A61F2/00
CPC分类号： A61F2/08 , A61F2002/0894
摘要： A surgical procedure is described for the restoration of eyelid function in individuals suffering from ptosis or upper eyelid droop syndrome that makes a patient unable to voluntarily fully raise an eyelid. The surgical procedure includes implantation and suturing of eye drop (pH) activated and actuated fibrous contractile and expansive artificial muscles such as pH active hydrogels of polyacrylonitrile (PAN) artificial muscles that are surgically implanted and sutured under the superior palpebral conjunctiva in a serpentine parallel configuration with respect to the tarsal (meibomian) glands of the upper eyelid and anchored to the tissues of superior fornix.
摘要翻译：描述了用于恢复患有上睑下垂或上眼睑下垂综合征的个体中的眼睑功能的外科手术，其使患者不能自愿完全抬起眼睑。外科手术包括植入和缝合眼药水（pH）激活和致动的纤维收缩和膨胀人造肌肉，例如聚丙烯腈（PAN）人造肌肉的pH活性水凝胶，其以蜿蜒平行配置手术植入和缝合在上睑结膜下相对于上眼睑的睑板腺（睑板腺）腺，并锚固于上穹窿的组织。

10. 发明申请

US20070150058A1 Surgical correction of ptosis polymeric artificial muscles 有权
标题翻译：下垂聚合人工肌肉的外科矫正
公开(公告)号：US20070150058A1
公开(公告)日：2007-06-28
申请号：US11318665
申请日：2005-12-24
申请人： Mohsen Shahinpoor , David Soltanpour
发明人： Mohsen Shahinpoor , David Soltanpour
IPC分类号： A61F2/08
CPC分类号： A61F2/08 , A61F2002/0894
摘要： A surgical procedure is described for the restoration of eyelid function in individuals suffering from ptosis or upper eyelid droop syndrome that makes a patient unable to voluntarily fully raise an eyelid. The surgical procedure includes implantation and suturing of eye drop (pH) activated and actuated fibrous contractile and expansive artificial muscles such as pH active hydrogels of polyacrylonitrile (PAN) artificial muscles that are surgically implanted and sutured under the superior palpebral conjunctiva in a serpentine parallel configuration with respect to the tarsal (meibomian) glands of the upper eyelid and anchored to the tissues of superior fornix.
摘要翻译：描述了用于恢复患有上睑下垂或上眼睑下垂综合征的个体中的眼睑功能的外科手术，其使患者不能自愿完全抬起眼睑。外科手术包括植入和缝合眼药水（pH）激活和致动的纤维收缩和膨胀人造肌肉，例如聚丙烯腈（PAN）人造肌肉的pH活性水凝胶，其以蜿蜒平行配置手术植入和缝合在上睑结膜下相对于上眼睑的睑板腺（睑板腺）腺，并锚固于上穹窿的组织。

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