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1. 发明申请

US20120009657A1 NOVEL FUSION CARBONIC ANHYDRASE/CELLULOSE BINDING POLYPEPTIDE ENCODED BY A NOVEL HYBRID GENE, AND METHOD OF CREATING AND USING THE SAME 审中-公开
标题翻译：由新型混合基因编码的新型融合碳纳米管/纤维素结合多肽及其制造和使用方法
公开(公告)号：US20120009657A1
公开(公告)日：2012-01-12
申请号：US13191497
申请日：2011-07-27
申请人： Mohammed . Ataai , Robert Dilmore , Yee Soong , Richard Koepsel , Zhu Liu
发明人： Mohammed . Ataai , Robert Dilmore , Yee Soong , Richard Koepsel , Zhu Liu
IPC分类号： B01D53/62
CPC分类号： C12N9/88 , B01D53/62 , B01D53/84 , B01D2255/804 , B01D2257/504 , C07K2319/20 , C12Y402/01001 , Y02A50/2358 , Y02C10/02 , Y02C10/04 , Y02P20/152 , Y02P20/59
摘要： The invention relates a novel hybrid carbonic anhydrase catalyst with the potential to contribute significantly to meeting targeted reductions in greenhouse gas emissions. In a preferred embodiment of the present invention at least a portion of a cellulose binding domain (CBD) of a protein is fused to another protein, carbonic anhydrase, (CA) to create a new multifunctional protein which can bind tightly to cellulose while maintaining its native catalytic ability to process CO2. The resulting CA-CBD hybrid polypeptide can be immobilized to a cellulose support and used to cost-effectively capture CO2 from gas streams and other CO2-rich environs.
摘要翻译：本发明涉及一种新的混合碳酸酐酶催化剂，其潜力可大大有助于实现温室气体排放的有针对性的减少。在本发明的优选实施方案中，蛋白质的纤维素结合结构域（CBD）的至少一部分与另一种蛋白质碳酸酐酶（CA）融合以产生新的多功能蛋白质，其可以与纤维素紧密结合，同时保持其天然催化能力来处理二氧化碳。所得到的CA-CBD杂合多肽可以固定在纤维素载体上，并用于从气流和其他富含CO 2的环境中成本有效地捕获CO 2。

2. 发明申请

US20110045557A1 Novel Fusion Carbonic Anhydrase/Cellulose Binding Polypeptide Encoded by a Novel Hybrid Gene, and Method of Creating and Using the Same 审中-公开
标题翻译：由新型杂合基因编码的新型融合碳酸酐酶/纤维素结合多肽及其制备和使用方法
公开(公告)号：US20110045557A1
公开(公告)日：2011-02-24
申请号：US11829359
申请日：2007-07-27
申请人： Mohammed Ataai , Robert Dilmore , Yee Soong , Richard Koepsel , Zhu Liu
发明人： Mohammed Ataai , Robert Dilmore , Yee Soong , Richard Koepsel , Zhu Liu
IPC分类号： C12P7/62 , C12N9/02 , C07H21/04 , C12N15/63 , C12N11/12
CPC分类号： C12N9/88 , B01D53/62 , B01D53/84 , B01D2255/804 , B01D2257/504 , C07K2319/20 , C12Y402/01001 , Y02A50/2358 , Y02C10/02 , Y02C10/04 , Y02P20/152 , Y02P20/59
摘要： The invention relates a novel hybrid carbonic anhydrase catalyst with the potential to contribute significantly to meeting targeted reductions in greenhouse gas emissions. In a preferred embodiment of the present invention at least a portion of a cellulose binding domain (CBD) of a protein is fused to another protein, carbonic anhydrase, (CA) to create a new multi-functional protein which can bind tightly to cellulose while maintaining its native catalytic ability to process CO2. The resulting CA-CBD hybrid polypeptide can be immobilized to a cellulose support and used to cost-effectively capture CO2 from gas streams and other CO2-rich environs.
摘要翻译：本发明涉及一种新的混合碳酸酐酶催化剂，其潜力可大大有助于实现温室气体排放的有针对性的减少。在本发明的优选实施方案中，蛋白质的纤维素结合结构域（CBD）的至少一部分与另一种蛋白质碳酸酐酶（CA）融合，以产生可与纤维素紧密结合的新的多功能蛋白质，同时保持其天然催化能力来处理二氧化碳。所得到的CA-CBD杂合多肽可以固定在纤维素载体上，并用于从气流和其他富含CO 2的环境中成本有效地捕获CO 2。

3. 发明申请

US20130058910A1 DECONTAMINATION OF CHEMICAL AND BIOLOGICAL AGENTS 审中-公开
标题翻译：化学和生物代谢物的去除
公开(公告)号：US20130058910A1
公开(公告)日：2013-03-07
申请号：US13406508
申请日：2012-02-27
申请人： Richard Koepsel , Gabriel Amitai , Alan J. Russell , Hironobu Murata
发明人： Richard Koepsel , Gabriel Amitai , Alan J. Russell , Hironobu Murata
IPC分类号： A62D3/30 , A01P1/00 , C08F220/56 , A01N37/46
CPC分类号： C08F220/54 , A01N33/12 , A01N33/24 , A01N63/02 , A62D3/02 , A62D2101/02 , A62D2101/04 , D01D5/0007 , D01F1/103 , D01F6/70 , C08F220/52 , A01N25/34 , A01N59/00 , A01N59/08 , A01N59/12
摘要： A system includes at least one oxidase. at least one haloperoxidase; at least a first polymer including groups exhibiting nucleophilic activity for organophosphorus compounds, and a source of halide ions to serve as a substrate for haloperoxidase-catalyzed generation of halogens. The source of halide ions may, for example, include salt crystals or a salt in an extended release system. In a number of embodiments, the first polymer includes halide ions.
摘要翻译：系统包括至少一种氧化酶。至少一种卤代过氧化物酶; 至少包括对有机磷化合物显示亲核活性的基团的第一聚合物，以及用作卤代过氧化物酶催化产生卤素的底物的卤离子源。卤离子源可以例如在延长释放系统中包括盐晶体或盐。在许多实施方案中，第一聚合物包括卤离子。

4. 发明申请

US20080286319A9 Antimicrobial surfaces and methods for preparing antimicrobial surfaces 审中-公开
标题翻译：抗微生物表面和制备抗菌表面的方法
公开(公告)号：US20080286319A9
公开(公告)日：2008-11-20
申请号：US10887029
申请日：2004-07-07
申请人： Alan Russell , Richard Koepsel , Sang Lee , Krzysztof Matyjaszewski
发明人： Alan Russell , Richard Koepsel , Sang Lee , Krzysztof Matyjaszewski
IPC分类号： A01N25/34
CPC分类号： A01N33/12 , A01N57/34 , A61L2/232
摘要： The present invention relates to biocidal articles. In an embodiment the biocidal article comprises a plurality of polymers having biocidally active groups. The polymers are attached to a surface and may have a polydispersity less than 3. The biocidally active groups may comprise at least one of a quaternary ammonium salt, a quaternary phosphonium salt or a chloroamine. The attached polymers may be any microstructure, topology or composition, such as, a homopolymer, block copolymer, multiblock copolymer, a random copolymer, graft polymer, a branched or a hyperbranched polymer, and a gradient copolymer. The present invention also comprises a process for the preparation of a biocidal article. Embodiments of the process comprise polymerizing radically polymerizable monomers from an initiator attached to a surface, wherein at least a portion of the monomers comprise a group capable of being converted to a biocidally active group, and converting the group to the biocidally active group.
摘要翻译：本发明涉及杀生物制品。在一个实施方案中，杀生物制品包含多个具有生物活性基团的聚合物。聚合物连接到表面并且可以具有小于3的多分散性。生物活性基团可以包含季铵盐，季鏻盐或氯胺中的至少一种。连接的聚合物可以是任何微结构，拓扑结构或组合物，例如均聚物，嵌段共聚物，多嵌段共聚物，无规共聚物，接枝聚合物，支链或超支化聚合物和梯度共聚物。本发明还包括制备杀生物制品的方法。该方法的实施方案包括将可自由基聚合的单体从附着于表面的引发剂聚合，其中至少一部分单体包含能够转化为生物活性基团的基团，并将该基团转化为生物活性基团。

5. 发明申请

US20070232699A1 Self assembled nanostructures and mehods for preparing the same 失效
标题翻译：自组装纳米结构和制备方法
公开(公告)号：US20070232699A1
公开(公告)日：2007-10-04
申请号：US11237838
申请日：2005-09-27
申请人： Alan Russell , Richard Koepsel , Sang Lee
发明人： Alan Russell , Richard Koepsel , Sang Lee
IPC分类号： A61K31/16 , C07C237/16
CPC分类号： C07C233/38 , A61K9/1274 , A61K31/14 , A61K31/16 , B82Y5/00 , Y02A50/473 , Y10S977/712 , Y10S977/797 , Y10S977/882 , Y10T428/2982
摘要： The present invention provides amphiphilic diacetylene compounds, and compositions and self-assembled nanotubes containing the same. Also provided are methods of producing the compounds, compositions, and nanotubes of the invention, and methods of destroying or inhibiting the growth or proliferation of microorganisms using the nanotubes of the present invention.
摘要翻译：本发明提供两亲性乙炔化合物，以及含有该双乙炔化合物的组合物和自组装纳米管。还提供了制备本发明的化合物，组合物和纳米管的方法，以及使用本发明的纳米管破坏或抑制微生物生长或增殖的方法。

6. 发明申请

US20060008490A1 Antimicrobial surfaces and methods for preparing antimicrobial surfaces 审中-公开
标题翻译：抗微生物表面和制备抗菌表面的方法
公开(公告)号：US20060008490A1
公开(公告)日：2006-01-12
申请号：US10887029
申请日：2004-07-07
申请人： Alan Russell , Richard Koepsel , Sang Lee , Krzysztof Matyjaszewski
发明人： Alan Russell , Richard Koepsel , Sang Lee , Krzysztof Matyjaszewski
IPC分类号： A01N25/34
CPC分类号： A01N33/12 , A01N57/34 , A61L2/232
摘要： The present invention relates to biocidal articles. In an embodiment the biocidal article comprises a plurality of polymers having biocidally active groups. The polymers are attached to a surface and may have a polydispersity less than 3. The biocidally active groups may comprise at least one of a quaternary ammonium salt, a quaternary phosphonium salt or a chloroamine. The attached polymers may be any microstructure, topology or composition, such as, a homopolymer, block copolymer, multiblock copolymer, a random copolymer, graft polymer, a branched or a hyperbranched polymer, and a gradient copolymer. The present invention also comprises a process for the preparation of a biocidal article. Embodiments of the process comprise polymerizing radically polymerizable monomers from an initiator attached to a surface, wherein at least a portion of the monomers comprise a group capable of being converted to a biocidally active group, and converting the group to the biocidally active group.
摘要翻译：本发明涉及杀生物制品。在一个实施方案中，杀生物制品包含多个具有生物活性基团的聚合物。聚合物连接到表面并且可以具有小于3的多分散性。生物活性基团可以包含季铵盐，季鏻盐或氯胺中的至少一种。连接的聚合物可以是任何微结构，拓扑结构或组合物，例如均聚物，嵌段共聚物，多嵌段共聚物，无规共聚物，接枝聚合物，支链或超支化聚合物和梯度共聚物。本发明还包括制备杀生物制品的方法。该方法的实施方案包括将可自由基聚合的单体从附着于表面的引发剂聚合，其中至少一部分单体包含能够转化为生物活性基团的基团，并将该基团转化为生物活性基团。

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