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1. 发明授权

US4985362A Process of purifying tPA 失效
标题翻译：净化tPA的过程
公开(公告)号：US4985362A
公开(公告)日：1991-01-15
申请号：US97678
申请日：1987-09-17
申请人： Mitsuyoshi Morii , Masaharu Ohoka , Toshihiko Suzuki , Katsuyuki Suzuki , Nobuhiro Kawashima , Noriko Morii , Kunizou Mori
发明人： Mitsuyoshi Morii , Masaharu Ohoka , Toshihiko Suzuki , Katsuyuki Suzuki , Nobuhiro Kawashima , Noriko Morii , Kunizou Mori
IPC分类号： C07K16/00 , C07K1/18 , C12N9/64 , C12N9/72
CPC分类号： C12N9/6459 , C12Y304/21069 , Y10S435/815
摘要： Tissue plasminogen activator (tPA) species having a molecular weight of about 70,000 daltons is isolated in a purified form from a crude tPA preparation containing various tPA species having different molecular weights by bringing the crude tPA preparation into contact with a cation exchanger in advance and separating the desired tPA species selectively from the cation exchanger by means of the salt gradient elution method.
摘要翻译：分子量约70,000道尔顿的组织纤溶酶原激活物（tPA）物质以纯化形式从包含不同分子量的各种tPA物质的粗制tPA制剂中分离，通过使粗制tPA制剂预先与阳离子交换剂接触并分离通过盐梯度洗脱法选择性地从阳离子交换剂中选择所需的tPA种类。

2. 发明授权

US4978620A Process for separating single-chain TPA and double-chain from each other 失效
标题翻译：单链TPA和双链分离的方法
公开(公告)号：US4978620A
公开(公告)日：1990-12-18
申请号：US183757
申请日：1988-04-07
申请人： Mitsuyoshi Morii , Masaharu Ohoka , Toshihiko Suzuki , Katsuyuki Suzuki , Nobuhiro Kawashima , Noriko Morii , Kunizo Mori
发明人： Mitsuyoshi Morii , Masaharu Ohoka , Toshihiko Suzuki , Katsuyuki Suzuki , Nobuhiro Kawashima , Noriko Morii , Kunizo Mori
IPC分类号： C12N9/64 , A61K38/00 , C12N9/72
CPC分类号： C12N9/6459 , C12Y304/21069 , A61K38/00 , Y10S435/815
摘要： The distinction of tissue plasminogen activator, especially, the separation of its single-chain species and double-chain species is effected by using the Erythrina trypsin inhibitor which occurs in seeds of a plant of the Erythrina species.

3. 发明授权

US4898825A Methods for purification of single-chain and double-chain tissue plasminogen activator 失效
标题翻译：纯化单链和双链组织纤溶酶原激活物的方法
公开(公告)号：US4898825A
公开(公告)日：1990-02-06
申请号：US43746
申请日：1987-04-29
申请人： Mitsuyoshi Morii , Masaharu Ohoka , Toshihiko Suzuki , Katsuyuki Suzuki , Nobuhiro Kawashima , Noriko Morii , Kunizo Mori
发明人： Mitsuyoshi Morii , Masaharu Ohoka , Toshihiko Suzuki , Katsuyuki Suzuki , Nobuhiro Kawashima , Noriko Morii , Kunizo Mori
IPC分类号： A61K38/00 , C12N9/72
CPC分类号： C12N9/6459 , C12Y304/21069 , A61K38/00 , Y10S435/814 , Y10S435/815
摘要： A mixture containing a single-chain tissue plasminogen activator (tPA) and/or double-chain tPA is brought into close contact with a column carrying an immobilized Erythrina trypsin inhibitor as an affinity agent. Adsorbed protiens are eluted with eluents having different pHs with or without arginine or benzamidine, so that single-chain tPA is obtained in the eluent with a pH at least 4.5 and double-chain tPA is obtained in the eluent with a pH lower than 4.5.
摘要翻译：将含有单链组织纤溶酶原激活剂（tPA）和/或双链tPA的混合物与携带固定化的Erythrina胰蛋白酶抑制剂的柱作为亲和剂紧密接触。吸附的质子用具有或不具有精氨酸或苄脒的不同pH的洗脱液洗脱，使得在洗脱液中获得单链tPA，pH至少为4.5，并且在pH低于4.5的洗脱液中获得双链tPA。

4. 发明授权

US5110736A Purificaiton procedure of tPA from crude preparations 失效
标题翻译： TPA从原料制备中的纯化程序
公开(公告)号：US5110736A
公开(公告)日：1992-05-05
申请号：US602387
申请日：1990-10-24
申请人： Mitsuyoshi Morii , Masaharu Ohoka , Nobuhiro Kawashima , Noriko Morii , Toshihiko Suzuki
发明人： Mitsuyoshi Morii , Masaharu Ohoka , Nobuhiro Kawashima , Noriko Morii , Toshihiko Suzuki
IPC分类号： C12N9/64 , C12N9/72 , C12R1/91
CPC分类号： C12N9/6459 , C12Y304/21069
摘要： Crude tPA containing, as an impurity, a protein which is reactive with an anti-human tPA antibody and has a molecular weight of 110,000.+-.20,000 daltons is purified by bringing the crude tPA into close contact with an affinity reagent containing an immobilized Kunitz inhibitor which is produced in seeds of Erythrina latissima and other Erythrina plants and acts as an inhibitor on trypsin, plasmin and tPA but does not act on urokinase, so that tPA is collected selectively.
摘要翻译：作为杂质含有与抗人tPA抗体反应并具有110,000 +/- 20,000道尔顿的分子量的蛋白质的粗tPA通过使粗制tPA与含有固定化的Kunitz的亲和试剂紧密接触来纯化抑制剂，其在鸢尾花和其他红藻属植物的种子中产生，并且作为胰蛋白酶，纤溶酶和tPA的抑制剂，但不对尿激酶起作用，从而选择性地收集tPA。

5. 发明授权

US09427213B2 Breast measurement apparatus 有权
标题翻译：乳房测量仪
公开(公告)号：US09427213B2
公开(公告)日：2016-08-30
申请号：US13880569
申请日：2011-10-18
申请人： Toshihiko Suzuki , Yutaka Yamashita , Yukio Ueda , Etsuko Yamaki , Daisuke Yamashita , Kenji Yoshimoto , Harumi Sakahara , Hiroyuki Ogura , Hatsuko Nasu
发明人： Toshihiko Suzuki , Yutaka Yamashita , Yukio Ueda , Etsuko Yamaki , Daisuke Yamashita , Kenji Yoshimoto , Harumi Sakahara , Hiroyuki Ogura , Hatsuko Nasu
IPC分类号： A61B5/00 , A61B8/08 , A61B8/00 , A61B8/14 , A61B10/00
CPC分类号： A61B8/5261 , A61B5/0035 , A61B5/0073 , A61B5/0091 , A61B5/4312 , A61B5/6835 , A61B5/708 , A61B5/72 , A61B5/7425 , A61B8/0825 , A61B8/14 , A61B8/406 , A61B8/4227 , A61B8/4281 , A61B8/4416 , A61B8/4444 , A61B8/4455 , A61B8/4477 , A61B8/5207 , A61B10/0041 , A61B2562/146
摘要： A breast measurement apparatus comprises a receptacle for surrounding a breast; a plurality of optical fibers for irradiating the breast with examination light and detecting transmitted scattered light from the breast; an inner image generation unit for generating an optical CT image concerning the breast according to a detection signal of the transmitted scattered light; an ultrasonic probe, arranged so as to face the inside of the receptacle, for scanning the breast with an ultrasonic wave and receiving a reflected wave from the breast; an image generation unit for generating an ultrasonic image concerning the breast according to the reflected wave; and a mechanism for injecting and discharging a liquid interface agent into and from the inside of the receptacle.
摘要翻译：乳房测量装置包括用于围绕乳房的容器; 多个光纤，用于用检查光照射乳房，并检测来自乳房的透射散射光; 内部图像生成单元，根据所发送的散射光的检测信号生成与乳房相关的光学CT图像; 超声波探头，布置成面向容器的内部，用于以超声波扫描乳房并从乳房接收反射波; 图像生成单元，其根据反射波生成与乳房相关的超声波图像; 以及用于将液体界面剂注入和排出到容器的内部的机构。

6. 发明授权

US08896409B2 Non-linear resistive element and manufacturing method thereof 有权
标题翻译：非线性电阻元件及其制造方法
公开(公告)号：US08896409B2
公开(公告)日：2014-11-25
申请号：US13822030
申请日：2011-10-05
申请人： Hideyuki Okinaka , Naoyuki Tsukamoto , Toshihiko Suzuki , Hiroyuki Otsuki
发明人： Hideyuki Okinaka , Naoyuki Tsukamoto , Toshihiko Suzuki , Hiroyuki Otsuki
IPC分类号： H01C7/10 , H01C7/12 , H01C7/112
CPC分类号： H01C7/12 , H01C7/10 , H01C7/1006 , H01C7/112 , Y02E60/13
摘要： Provided is a technique to secure compositional or microstructural uniformity of a ceramic sintered body while increasing the area of the ceramic sintered boy, thus improving basic performance including non-linearity, maximum withstand energy and aging characteristics. A plurality of small varistor pieces 11 and insulating resin are kneaded and extruded for shaping, whereby a sheet-form varistor layer 13 can be formed where a plurality of small varistor pieces 11 are spaced from one another and are aligned on the same plane, and the adjacent small varistor pieces 11 are bonded via insulating resin.
摘要翻译：提供了一种在增加陶瓷烧结体的面积的同时保证陶瓷烧结体的组成或微结构均匀性的技术，从而提高包括非线性，最大耐受能量和老化特性的基本性能。多个小变阻器片11和绝缘树脂被捏合和挤压成形，由此可以形成片状可变电阻层13，其中多个小压敏电阻片11彼此间隔开并排列在同一平面上，并且相邻的小变阻器片11通过绝缘树脂接合。

7. 发明授权

US08577161B2 Reproduction apparatus 有权
标题翻译：繁殖装置
公开(公告)号：US08577161B2
公开(公告)日：2013-11-05
申请号：US13492275
申请日：2012-06-08
申请人： Toshihiko Suzuki
发明人： Toshihiko Suzuki
IPC分类号： G06K9/46
CPC分类号： H04N5/772 , H04N5/783 , H04N5/907 , H04N9/8042 , H04N9/8211
摘要： A reproduction apparatus includes a reproduction unit that reproduces plural moving image data having different frame rates from a recording medium, an output unit that outputs the reproduced moving image data to a display device, a setting unit that sets one of a first and a second reproduction modes, and a control unit that controls the output unit to select some of frames of the reproduced moving image data and output moving image data of the selected frames according to an instruction for high-speed reproduction. In the first reproduction mode, the control unit selects frames at a predetermined frame interval according to reproduction speed for the high-speed reproduction. In the second reproduction mode, the control unit selects frames at a frame interval determined based on the reproduction speed for the high-speed reproduction and a frame rate of the reproduced moving image data.
摘要翻译：再现装置包括从记录介质再现具有不同帧速率的多个运动图像数据的再现单元，将再现的运动图像数据输出到显示装置的输出单元，设置单元，其将第一和第二再现模式和控制单元，其控制输出单元根据用于高速再现的指令来选择再现的运动图像数据的一些帧并输出所选择的帧的运动图像数据。在第一再现模式中，控制单元根据用于高速再现的再现速度以预定的帧间隔选择帧。在第二重放模式中，控制单元以基于高速再现的再现速度和再现的运动图像数据的帧速率所确定的帧间隔来选择帧。

8. 发明申请

US20130100449A1 METHOD AND DEVICE FOR MEASURING SCATTERING-ABSORPTION BODY 有权
标题翻译：用于测量散射吸收体的方法和装置
公开(公告)号：US20130100449A1
公开(公告)日：2013-04-25
申请号：US13695362
申请日：2011-03-29
申请人： Etsuko Yamaki , Yutaka Yamashita , Motoki Oda , Hiroaki Suzuki , Toshihiko Suzuki , Hiroshi Watanabe , Shunsaku Koga
发明人： Etsuko Yamaki , Yutaka Yamashita , Motoki Oda , Hiroaki Suzuki , Toshihiko Suzuki , Hiroshi Watanabe , Shunsaku Koga
IPC分类号： G01N21/17
CPC分类号： G01N21/17 , A61B5/14546 , A61B5/1455 , A61B2562/0242 , G01N21/359 , G01N21/49
摘要： Light irradiates one light incident position on the surface of a scattering-absorption body. The light that propagates through the interior of the scattering-absorption body is detected at one light detecting position on the surface of the scattering-absorption body. On the basis of a light detection signal, a temporal profile of the light intensity of the detected light is acquired, and on the basis of the temporal profile, an mean optical path length of the light in the interior of the scattering-absorption body and information relating to the amount of substance to be measured in a region to be measured are calculated. The information relating to the amount of substance to be measured is corrected on the basis of the mean optical path length, such that the longer the mean optical path length, the greater the amount of substance to be measured is.
摘要翻译：光照射散射吸收体表面上的一个光入射位置。在散射吸收体的表面的一个光检测位置处检测通过散射吸收体的内部传播的光。基于光检测信号，获取检测光的光强度的时间分布，并且基于时间分布，散射吸收体内部的光的平均光路长度和计算与要测量的区域中的待测物质量有关的信息。基于平均光程长度校正与被测量物质量有关的信息，使得平均光程长度越长，待测物质量越多。

9. 发明授权

US07844156B2 Optical waveguide film and optical transmitter and receiver module 有权
标题翻译：光波导薄膜和光发射机和接收模块
公开(公告)号：US07844156B2
公开(公告)日：2010-11-30
申请号：US12366371
申请日：2009-02-05
申请人： Shigemi Ohtsu , Akira Fujii , Kazutoshi Yatsuda , Masahiro Igusa , Toshihiko Suzuki , Keishi Shimizu
发明人： Shigemi Ohtsu , Akira Fujii , Kazutoshi Yatsuda , Masahiro Igusa , Toshihiko Suzuki , Keishi Shimizu
IPC分类号： G02B6/10
CPC分类号： G02B6/43 , G02B6/4214
摘要： An optical waveguide includes: an optical waveguide core through which light propagates, at least one end portion of the optical waveguide core in a longitudinal direction thereof having an inclined surface; a reflective layer provided on the inclined surface and formed by a metal layer of silver or a silver alloy; a protective layer disposed to cover the reflective layer; and a cladding portion enclosing the optical waveguide core and having a lower refractive index than that of the optical waveguide core.
摘要翻译：光波导包括：光传播的光波导芯，光波导芯的纵向方向的至少一端部具有倾斜面; 反射层，设置在倾斜表面上，由银或银合金的金属层形成; 设置成覆盖反射层的保护层; 以及包围光波导芯并且折射率低于光波导芯的折射率的包层部。

10. 发明授权

US07806402B2 Bill discriminating and counting apparatus 有权
标题翻译：票据识别和计数装置
公开(公告)号：US07806402B2
公开(公告)日：2010-10-05
申请号：US11664995
申请日：2004-10-12
申请人： Tomoyasu Sato , Atsushi Suzuki , Toshihiko Suzuki
发明人： Tomoyasu Sato , Atsushi Suzuki , Toshihiko Suzuki
IPC分类号： B65H1/06
CPC分类号： B65H5/062 , B65H5/002 , B65H29/001 , B65H2301/141 , B65H2701/1912 , G07D11/0003 , G07D11/0018 , G07D11/003
摘要： A bill discriminating and counting apparatus in which a plurality of bills with different sizes are filled between side hopper members and fed into a transport path by a feeding mechanism. The feeding mechanism comprises a plurality of rollers disposed in a bilaterally symmetrical state. The plurality of rollers are arranged so that, when a distance between the side hopper members is adjusted according to the longitudinal dimension of a bill with the maximum dimension in the longitudinal direction and a bill with the minimum dimension in the longitudinal direction is disposed at a position where the bill is brought into contact with one of the side hopper members, at least a part of the rollers installed on the opposite side of the side hopper member where the bill is brought into contact therewith is brought into contact with the bill. Also, the feeding mechanism comprises a guide member guiding the bill to the inlet of the transport path. The guide member comprises a guide surfaces formed so that the opening area thereof is gradually increased toward the both ends thereof, and the guide surfaces are formed so that the opening area thereof is converged to zero from the insert port toward the inlet of the transport path.
摘要翻译：一种纸币识别和计数装置，其中将多个不同尺寸的纸币填充在侧料斗构件之间并通过进给机构供给到输送路径中。进给机构包括以双边对称状态设置的多个辊。多个辊被布置成使得当根据纵向方向上具有最大尺寸的纸币的纵向尺寸来调节侧料斗构件之间的距离，并且在纵向方向上具有最小尺寸的纸币设置在使纸币与一个侧面料斗构件接触的位置，安装在侧面料斗构件的与纸币接触的相反侧的至少一部分辊与纸币接触。而且，进给机构包括将纸币引导到输送路径的入口的引导部件。引导构件包括形成为使得其开口面积朝向其两端逐渐增加的引导表面，并且引导表面形成为使得其开口面积从插入口朝向输送路径的入口收敛到零。

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